Michael A. Brehm

13.8k citations

161 papers · 8.4k indexed · 3 hit papers · h-index 52

Impact in

Immunology top 0.2%
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
Virology top 1%
- HIV Research and Treatment

Papers in

Immunology 95
- Immune Cell Function and Interaction 66
- T-cell and B-cell Immunology 45
- Immunotherapy and Immune Responses 38
- Immune Response and Inflammation 12
Virology 7

Co-authors: Dale L. Greiner Leonard D. Shultz Raymond M. Welsh Liisa K. Selin J. Víctor García Keith A. Daniels Aldo A. Rossini Sonal Jangalwe
Journals: The Journal of Immunology (25 papers)Blood (6 papers)Journal of Virology (6 papers)Cancer Research (5 papers)The FASEB Journal (5 papers)
Partner nations: United States Germany Australia

In The Last Decade

Michael A. Brehm

155 papers receiving 8.4k citations

Hit Papers

align trajectories log scale

Humanized mouse models for immuno-oncology research 2023 · 212 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2023 Nature Reviews Clinical Oncology
2016 Annual Review of Pathology Mechanisms of Disease
2012 Nature reviews. Immunology

Peers

Countries citing papers authored by Michael A. Brehm

Since Specialization

Citations

This map shows the geographic impact of Michael A. Brehm's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael A. Brehm with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael A. Brehm more than expected).

Fields of papers citing papers by Michael A. Brehm

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael A. Brehm. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael A. Brehm. The network helps show where Michael A. Brehm may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Michael A. Brehm, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael A. Brehm Line = papers co-authored together Michael A. Brehm links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	IRF2 loss is associated with reduced MHC I pathway transcripts in subsets of most human cancers and causes resistance to checkpoint immunotherapy in human and mouse melanomas Journal of Experimental & Clinical Cancer Research ·Gülce Sarı, Karthik Dhatchinamoorthy, Seham Moteeb Al-Motairi, Lydia Masako Ferreira, Michael A. Brehm, Kenneth L. Rock	2024	4
2	The role of quiescent thymic progenitors in TAL/LMO2-induced T-ALL chemotolerance Leukemia ·Kevin W. O’Connor, D. V. Karpova, K. Acht, Baokang Niu, Saikia Md Shakeel Iqbal, Justine E. Roderick, Keshab Kumar Karna, Rafaela De MendonÃƒÆ’Ã‚Â§a, Kai Hu, Haibo Liu, Rui Li, Michael A. Brehm, Lihua Julie Zhu, David J. Curtis, Cédric S. Tremblay, Michelle A. Kelliher	2024	4
3	Nuclear factor kappa B-dependent persistence of Salmonella Typhi and Paratyphi in human macrophages mBio ·Ana Paula Garbuio Cavalheiro, Songlin Li, Barría Flores, Joyce E. Karlinsey, Stephen J. Libby, А. А. Кнорре, Simon Grimble, Buthainah Saleh Alshamri, Dennis C. Ko, Michael A. Brehm, Dale L. Greiner, Leonard D. Shultz, Ferric C. Fang	2024	5
4	The co-receptor Neuropilin-1 enhances proliferation in inv(16) acute myeloid leukemia via VEGF signaling Leukemia ·Mahesh Hegde, Jorge L. M. Rodrigues, Roger Mulet‐Lazaro, Mayumi Sugita, Russell J. Parkinson, Kai Hu, Claudia Gebhard, Mónica L. Guzmán, John H. Bushweller, Lihua Julie Zhu, Michael A. Brehm, Scot A. Wolfe, Ruud Delwel, Lucio H. Castilla	2024	2
5	CDK4/6 Inhibition Sensitizes Intracranial Tumors to PD-1 Blockade in Preclinical Models of Brain Metastasis Clinical Cancer Research ·Naema Nayyar, Magali de Sauvage, Jane Chuprin, Emily Sullivan, Mohini Singh, Consuelo Torrini, Jörg Schülke, H. Mohler, Keith A. Daniels, Christopher Alvarez‐Breckenridge, А.И. Нетрусов, Michael A. Brehm, Priscilla K. Brastianos	2023	15
6	Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer Science Translational Medicine ·Elena Olegovna Chebakova, M. Zinge, Fernando Lúcio da, Peter Chhoy, Hira Lal Goel, Sanjana M Kamath, Lihua Julie Zhu, Rui Li, P.S. Luke, سیما جوینی پور, Hubert Pakula, И. Ш. Насибуллаев, Massimo Loda, Zhong Jiang, Michael A. Brehm, Arthur M. Mercurio	2023	29
7	PSGL-1 Blockade Induces Classical Activation of Human Tumor-associated Macrophages Cancer Research Communications ·Kevin Kauffman, Denise Manfra, Erin Oakley, Mohammad Zafari, J.M. Thomson, Ryan Phennicie, Elisabeth H. Vollmann, V. O. Nagibina, 立夫万, M. Slezáková, Jeanne Graziano, Elizabeth K. Culyba, Joseph Wahle, Carola H. Ries, Michael A. Brehm, Dolores Paulina Ramírez Flores, Igor Feldman, Tatiana I. Novobrantseva	2023	8
8	Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response Science Advances ·Joshua C. Doloff, Minglin Ma, Atieh Sadraei, Hok Hei Tam, Shady Farah, Jennifer Hollister‐Lock, Arturo J. Vegas, Omid Veiseh, Ma Luisa Baeza, Amanda Rakoski, Stephanie Aresta-Dasilva, Andrew Bader, Celine Vynssca, Gordon C. Weir, Michael A. Brehm, Leonard D. Shultz, Róbert Langer, Dale L. Greiner, Daniel G. Anderson	2023	12
9	An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis Molecular Therapy ·Batuhan Yenilmez, Satoshi Aizawa, Mark Kelly, Dimas Echeverria, LELI, Lawrence M. Lifshitz, Julia F. Alterman, Matthew Hassler, Surbhi Kansal, R. E. Koeler, Nicholas McHugh, Anna Brenske, Jacquelyn Sousa, Meixia Pan, Xianlin Han, Michael A. Brehm, Anastasia Khvorova, Michael Czech	2021	29
10	Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death Blood ·Justine E. Roderick, Rafaela De MendonÃƒÆ’Ã‚Â§a, JC Wilson, Kevin W. O’Connor, Katherine Tang, Boyao Zhang, Michael A. Brehm, Dale L. Greiner, Jun Yu, Lihua Julie Zhu, Michael R. Green, Michelle A. Kelliher	2020	9
11	Human Anti–HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1 The Journal of Immunology ·P. Vidhayasekaran, Mark Duval, Claudia Carbone, Smita Jaiswal, Aaron Wallace, Paulo Aparecido Dias da Silva Silva, Ann Dauphin, Michael A. Brehm, Dale L. Greiner, Leonard D. Shultz, Jeremy Luban, Lisa A. Cavacini	2018	6
12	Humanized nonobese diabetic- scid IL2rγ ^null mice are susceptible to lethal Salmonella Typhi infection Proceedings of the National Academy of Sciences ·Stephen J. Libby, Michael A. Brehm, Dale L. Greiner, Leonard D. Shultz, Michael McClelland, Kelly D. Smith, Brad T. Cookson, Joyce E. Karlinsey, Traci L. Kinkel, Steffen Porwollik, Rocı́o Canals, Lisa A. Cummings, Ferric C. Fang	2010	98
13	NOD-scid IL2rγnull Mouse Model of Human Skin Transplantation and Allograft Rejection Transplantation ·Waldemar J. Racki, Laurence Covassin, Michael A. Brehm, Muhammad Nuramzan Iftari, Ronald A. Ignotz, Raymond M. Dunn, Joseph Laning, Chenchen Zhou, Aldo A. Rossini, Leonard D. Shultz, Dale L. Greiner	2010	57
14	TLR Agonists Abrogate Costimulation Blockade-Induced Prolongation of Skin Allografts The Journal of Immunology ·Thomas B. Thornley, Michael A. Brehm, Thomas G. Markees, Leonard D. Shultz, John P. Mordes, Raymond M. Welsh, Aldo A. Rossini, Dale L. Greiner	2006	106
15	Tec Kinases Itk and Rlk Are Required for CD8+ T Cell Responses to Virus Infection Independent of Their Role in CD4+ T Cell Help The Journal of Immunology ·Mohd Ezuan Abdul Jalil, Michael A. Brehm, Raymond M. Welsh, Leslie J. Berg	2006	44
16	Partial versus Full Allogeneic Hemopoietic Chimerization Is a Preferential Means to Inhibit Type 1 Diabetes as the Latter Induces Generalized Immunosuppression The Journal of Immunology ·David Serreze, Melissa Osborne, Yi‐Guang Chen, Harold D. Chapman, Todd Pearson, Michael A. Brehm, Dale L. Greiner	2006	19
17	Rapid Production of TNF-α following TCR Engagement of Naive CD8 T Cells The Journal of Immunology ·Michael A. Brehm, Keith A. Daniels, Raymond M. Welsh	2005	83
18	Preapoptotic Phenotype of Viral Epitope-Specific CD8 T Cells Precludes Memory Development and Is an Intrinsic Property of the Epitope The Journal of Immunology ·Annas Bin Adil, Michael A. Brehm, Raymond M. Welsh	2004	15
19	Direct Visualization of Cross-Reactive Effector and Memory Allo-Specific CD8 T Cells Generated in Response to Viral Infections The Journal of Immunology ·Michael A. Brehm, Thomas G. Markees, Keith A. Daniels, Dale L. Greiner, Aldo A. Rossini, Raymond M. Welsh	2003	117
20	Dynamics of Memory T Cell Proliferation Under Conditions of Heterologous Immunity and Bystander Stimulation The Journal of Immunology ·Sung-Kwon Kim, Michael A. Brehm, Raymond M. Welsh, Liisa K. Selin	2002	76

About Michael A. Brehm

Michael A. Brehm is a scholar working on Immunology, Virology, Genetics, Hematology and Oncology, having authored 161 papers that have together received 8.4k indexed citations. Recurring topics across this work include Immune Cell Function and Interaction (66 papers), T-cell and B-cell Immunology (45 papers), Immunotherapy and Immune Responses (38 papers), Virus-based gene therapy research (23 papers), Diabetes and associated disorders (17 papers), Pancreatic function and diabetes (17 papers), CAR-T cell therapy research (14 papers) and Immune Response and Inflammation (12 papers). The work is most often cited by research in Immunology (4.4k citations), Virology (513 citations), Transplantation (184 citations), Oncology (1.8k citations) and Hematology (543 citations). Michael A. Brehm has collaborated with scholars based in United States, Germany and Australia. Frequent co-authors include Dale L. Greiner, Leonard D. Shultz, Raymond M. Welsh, Liisa K. Selin, J. Víctor García, Keith A. Daniels, Aldo A. Rossini, Sonal Jangalwe, Laurie L. Kenney and Lisa Burzenski. Their work appears in journals such as The Journal of Immunology, Blood, Journal of Virology, Cancer Research and The FASEB Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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