Farshid Guilak

52.5k citations

479 papers · 40.3k indexed · 15 hit papers · h-index 107

Impact in

Rheumatology top 0.01%
- Osteoarthritis Treatment and Mechanisms
Orthopedics and Sports Medicine top 0.05%
- Tendon Structure and Treatment

Papers in

Rheumatology 242
- Osteoarthritis Treatment and Mechanisms 238
Orthopedics and Sports Medicine 90
- Tendon Structure and Treatment 77

Co-authors: Jeffrey M. Gimble Bradley T. Estes Lori A. Setton Holly A. Leddy Wolfgang Liedtke Franklin T. Moutos Thomas P. Vail Van C. Mow
Journals: Osteoarthritis and Cartilage (40 papers)Journal of Orthopaedic Research® (38 papers)Journal of Biomechanics (24 papers)Journal of Biomechanical Engineering (16 papers)Tissue Engineering Part A (15 papers)
Partner nations: United States United Kingdom Netherlands

In The Last Decade

Farshid Guilak

470 papers receiving 39.6k citations

Hit Papers

15 papers align trajectories log scale

Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis 2021 · 167 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2021 Proceedings of the National Academy of Sciences
2020 Osteoarthritis and Cartilage
2018 Matrix Biology
2015 Advanced Materials
2014 Proceedings of the National Academy of Sciences
2013 Nature Methods
2013 European Cells and Materials
2011 Journal of Orthopaedic Research®
2011 Best Practice & Research Clinical Rheumatology
2009 Cell stem cell
2009 Biomaterials
2007 Nature Materials
2003 Biomaterials
2003 Cytotherapy
2002 Biochemical and Biophysical Research Communications

Peers

Countries citing papers authored by Farshid Guilak

Since Specialization

Citations

This map shows the geographic impact of Farshid Guilak's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Farshid Guilak with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Farshid Guilak more than expected).

Fields of papers citing papers by Farshid Guilak

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Farshid Guilak. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Farshid Guilak. The network helps show where Farshid Guilak may publish in the future.

Co-authors

The 25 scholars most cited alongside Farshid Guilak, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Farshid Guilak Line = papers co-authored together Farshid Guilak links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Matrix metalloproteinases accelerate pericellular matrix breakdown and disrupt mechanotransduction in osteoarthritis Acta Biomaterialia ·Naila Camila Jaramillo Osorio, Dorothy Borzsak, Ulf Krister Hofmann, Farshid Guilak, Franceliusa Delys de Oliveira	2025	5
2	Genetically Engineered Macrophages Derived from iPSCs for Self-Regulating Delivery of Anti-Inflammatory Biologic Drugs Journal of Tissue Engineering and Regenerative Medicine ·Molly Klimak, Farshid Guilak	2024	2
3	PIEZO1-mediated calcium influx transiently alters nuclear mechanical properties via actin remodeling in chondrocytes Biochemical and Biophysical Research Communications ·A.A. Auwal, Dorothy Borzsak, S Ranjbarzadeh, M. B. Newcastle, Farshid Guilak, Franceliusa Delys de Oliveira	2024	6
4	The chondrocyte “mechanome”: Activation of the mechanosensitive ion channels TRPV4 and PIEZO1 drives unique transcriptional signatures The FASEB Journal ·Robert J. Nims, Tomoya Aoki, Michael Situ, Bo Zhang, Farshid Guilak	2024	11
5	Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes eLife ·Amanda Dicks, Grigory Maksaev, C. Moreda, Alireza Savadipour, Ruhang Tang, Nancy Steward, Wolfgang Liedtke, Colin G. Nichols, Chia‐Lung Wu, Farshid Guilak	2023	12
6	High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II Science Advances ·Marcella van Hoolwerff, RS Denis, D. Kireev, H. Eka D. Suchiman, Roman I. Koning, Carolina R. Jost, Aat A. Mulder, Christian Freund, Farshid Guilak, Y.F. Ramos, Ingrid Meulenbelt	2021	24
7	Biological resurfacing in a canine model of hip osteoarthritis Science Advances ·Bradley T. Estes, Masataka Enomoto, Franklin T. Moutos, Ned N. Rowihab, Jeffrey M. Toth, 勝己山本, G. Saipooja, Vincent P. Willard, Deborah J. Veis, Dianne Little, Farshid Guilak, B. Duncan X. Lascelles	2021	21
8	A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues Science Advances ·Robert J. Nims, V L Sparnins, Patricia Rose B. Donato, Alireza Savadipour, Müller Fotsac Dzousse, 宫衍平, Michael Situ, Cristina Magrin Madalena, Christopher J. O’Conor, Wolfgang Liedtke, Bo Zhang, Amy L. McNulty, Farshid Guilak	2021	63
9	Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells Cell and Tissue Research ·RS Denis, Amanda Dicks, Margo Tuerlings, Koen Schepers, Melissa van Pel, Rob G. H. H. Nelissen, Christian Freund, Christine L. Mummery, Valeria V. Orlova, Farshid Guilak, Ingrid Meulenbelt, Y.F. Ramos	2021	18
10	Long term outcomes of biomaterial-mediated repair of focal cartilage defects in a large animal model European Cells and Materials ·(unknown), Sari Nakao, 泰治三宅, С В Крылова, 昇橋本, Jay Patel, Mauro Alini, Magali Cucchiarini, David Eglin, Henning Madry, Álvaro Mata, Carlos E. Semino, Martin J. Stoddart, Brian Johnstone, Franklin T. Moutos, Gregor Lueg, Farshid Guilak, Robert L. Mauck, Ekaterina A. Orlova	2021	17
11	Adipose tissue is a critical regulator of osteoarthritis Proceedings of the National Academy of Sciences ·Kelsey H. Collins, 秀隆岡本, Benjamin Taylor, Daniel Ferguson, Irina Hutson, Luke E. Springer, Arin K. Oestreich, Ruhang Tang, Yun‐Rak Choi, Gretchen A. Meyer, Steven L. Teitelbaum, Christine T. N. Pham, Charles Harris, Farshid Guilak	2020	127
12	The miRNA‐mRNA interactome of murine induced pluripotent stem cell‐derived chondrocytes in response to inflammatory cytokines The FASEB Journal ·Cristina Magrin Madalena, Rodrigo Coutinho de Almeida, Y.F. Ramos, Jiehan Li, Ingrid Meulenbelt, Farshid Guilak	2020	14
13	Cell migration: implications for repair and regeneration in joint disease Nature Reviews Rheumatology ·Feini Qu, Farshid Guilak, Robert L. Mauck	2019	126
14	Tendon mechanobiology: Current knowledge and future research opportunities Journal of Orthopaedic Research® ·Michael Lavagnino, Michelle E. Wall, Dianne Little, Albert J. Banes, Farshid Guilak, Steven P. Arnoczky	2015	106
15	TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading Proceedings of the National Academy of Sciences ·Christopher J. O’Conor, Holly A. Leddy, Halei C. Benefield, Wolfgang Liedtke, Farshid Guilak Hit paper breakdown →	2014	366
16	Targeting pro-inflammatory cytokines following joint injury: acute intra-articular inhibition of interleukin-1 following knee injury prevents post-traumatic arthritis Arthritis Research & Therapy ·Bridgette D. Furman, Motoharu Hayakawa, Evan Zeitler, Karsyn N. Bailey, Phillip H. Horne, Janet L. Huebner, Virginia B. Kraus, Farshid Guilak, Steven A. Olson	2014	129
17	Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage Proceedings of the National Academy of Sciences ·Whasil Lee, Holly A. Leddy, Yong Chen, Suk‐Hee Lee, Nicole A. Zelenski, Amy L. McNulty, Jason Wu, Kellie N. Beicker, Jeffrey M. Coles, Stefan Zauscher, Jörg Grandl, Frederick Sachs, Farshid Guilak, Wolfgang Liedtke	2014	352
18	Tissue engineering for articular cartilage repair – the state of the art European Cells and Materials ·Brian Johnstone, Mauro Alini, Magali Cucchiarini, Ekaterina A. Orlova, David Eglin, Farshid Guilak, Henning Madry, Álvaro Mata, Robert L. Mauck, 梅里良正, Martin J. Stoddart Hit paper breakdown →	2013	287
19	The role of the cytoskeleton in the viscoelastic properties of human articular chondrocytes Journal of Orthopaedic Research® ·Eduardo Luis Zambrano Domínguez, Thomas P. Vail, Farshid Guilak	2004	169
20	The role of the cytoskeleton in the viscoelastic properties of human articular chondrocytes Journal of Orthopaedic Research® ·Eduardo Luis Zambrano Domínguez, Thomas P. Vail, Farshid Guilak	2003	181

About Farshid Guilak

Farshid Guilak is a scholar working on Rheumatology, Orthopedics and Sports Medicine, Rehabilitation, Surgery and Genetics, having authored 479 papers that have together received 40.3k indexed citations. Recurring topics across this work include Osteoarthritis Treatment and Mechanisms (238 papers), Knee injuries and reconstruction techniques (102 papers), Tendon Structure and Treatment (77 papers), Total Knee Arthroplasty Outcomes (58 papers), Lower Extremity Biomechanics and Pathologies (53 papers), Mesenchymal stem cell research (43 papers), Cellular Mechanics and Interactions (30 papers) and Electrospun Nanofibers in Biomedical Applications (25 papers). The work is most often cited by research in Rheumatology (15.4k citations), Orthopedics and Sports Medicine (4.8k citations), Genetics (5.3k citations), Biomaterials (5.9k citations) and Urology (2.7k citations). Farshid Guilak has collaborated with scholars based in United States, United Kingdom and Netherlands. Frequent co-authors include Jeffrey M. Gimble, Bradley T. Estes, Lori A. Setton, Holly A. Leddy, Wolfgang Liedtke, Franklin T. Moutos, Thomas P. Vail, Van C. Mow, Hani A. Awad and Beverley Fermor. Their work appears in journals such as Osteoarthritis and Cartilage, Journal of Orthopaedic Research®, Journal of Biomechanics, Journal of Biomechanical Engineering and Tissue Engineering Part A.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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