Esther Castellano

2.4k total citations · 1 hit paper
20 papers, 1.7k citations indexed

About

Esther Castellano is a scholar working on Molecular Biology, Oncology and Immunology. According to data from OpenAlex, Esther Castellano has authored 20 papers receiving a total of 1.7k indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Molecular Biology, 9 papers in Oncology and 3 papers in Immunology. Recurrent topics in Esther Castellano's work include Protein Kinase Regulation and GTPase Signaling (9 papers), PI3K/AKT/mTOR signaling in cancer (8 papers) and Cancer-related Molecular Pathways (5 papers). Esther Castellano is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (9 papers), PI3K/AKT/mTOR signaling in cancer (8 papers) and Cancer-related Molecular Pathways (5 papers). Esther Castellano collaborates with scholars based in Spain, United Kingdom and Italy. Esther Castellano's co-authors include Julian Downward, Eugenio Santos, Jelena Urosevic, Mariano Barbacid, Carmen G. Lechuga, Eleanor Y. M. Sum, Luis Miguel Pedrero Esteban, Matthias Drosten, Carmen Guerra and Miguel Murillo and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Clinical Investigation and Nature Communications.

In The Last Decade

Esther Castellano

19 papers receiving 1.7k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

RAS Interaction with PI3K: More Than Just Another Effector Pathway

2011 549 citations Esther Castellano, Julian Downward Genes & Cancer profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Esther Castellano Spain	16	1.3k	458	243	223	172	20	1.7k
Christine Tan United States	10	1.2k 0.9×	487 1.1×	243 1.0×	187 0.8×	143 0.8×	17	1.9k
Jiyun Yoo South Korea	23	1.2k 0.9×	413 0.9×	245 1.0×	200 0.9×	143 0.8×	53	1.8k
Muling Mao United States	14	1.3k 1.0×	501 1.1×	222 0.9×	227 1.0×	120 0.7×	16	1.7k
Barbara Nicke Germany	14	1.1k 0.9×	397 0.9×	212 0.9×	293 1.3×	131 0.8×	24	1.5k
Maurizio Orlandini Italy	26	1.3k 1.0×	493 1.1×	217 0.9×	185 0.8×	94 0.5×	66	1.9k
Verline Justilien United States	21	1.3k 1.0×	475 1.0×	328 1.3×	261 1.2×	161 0.9×	31	1.7k
Florian J. Sulzmaier United States	16	959 0.8×	492 1.1×	312 1.3×	370 1.7×	126 0.7×	25	1.7k
Reyno Delrosario United States	17	1.1k 0.9×	655 1.4×	372 1.5×	239 1.1×	147 0.9×	20	1.7k
Kiran Mahajan United States	24	1.5k 1.1×	495 1.1×	273 1.1×	197 0.9×	384 2.2×	38	1.9k
Landon J. Inge United States	21	1.1k 0.8×	433 0.9×	307 1.3×	128 0.6×	242 1.4×	41	1.7k

Countries citing papers authored by Esther Castellano

Since Specialization

Citations

This map shows the geographic impact of Esther Castellano's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Esther Castellano with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Esther Castellano more than expected).

Fields of papers citing papers by Esther Castellano

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Esther Castellano. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Esther Castellano. The network helps show where Esther Castellano may publish in the future.

Co-authorship network of co-authors of Esther Castellano

This figure shows the co-authorship network connecting the top 25 collaborators of Esther Castellano. A scholar is included among the top collaborators of Esther Castellano based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Esther Castellano. Esther Castellano is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Baltanás, Fernando C., Rósula García‐Navas, Enrico Patrucco, et al.. (2025). SOS1 inhibitor BI-3406 shows in vivo antitumor activity akin to genetic ablation and synergizes with a KRAS ^G12D inhibitor in KRAS LUAD. Proceedings of the National Academy of Sciences. 122(11). e2422943122–e2422943122. 1 indexed citations

Castellano, Esther, et al.. (2025). Fibre tracing in biomedical images: An objective comparison between seven algorithms. PLoS ONE. 20(4). e0320006–e0320006. 1 indexed citations

Voisin, Mathieu-Benoı̂t, Juan F. De Paz, Vinothini Rajeeve, et al.. (2025). RAS–p110α signalling in macrophages is required for effective inflammatory response and resolution of inflammation. eLife. 13.

Baltanás, Fernando C., et al.. (2023). Critical requirement of SOS1 for tumor development and microenvironment modulation in KRASG12D-driven lung adenocarcinoma. Nature Communications. 14(1). 5856–5856. 15 indexed citations

Castellano, Esther, et al.. (2021). The Importance of Being PI3K in the RAS Signaling Network. Genes. 12(7). 1094–1094. 65 indexed citations

Vicente‐Manzanares, Miguel, et al.. (2021). The Crossroads between RAS and RHO Signaling Pathways in Cellular Transformation, Motility and Contraction. Genes. 12(6). 819–819. 54 indexed citations

Castellano, Esther, et al.. (2017). PI3K: A Crucial Piece in the RAS Signaling Puzzle. Cold Spring Harbor Perspectives in Medicine. 8(6). a031450–a031450. 53 indexed citations

Castellano, Esther, Míriam Molina‐Arcas, Philip East, et al.. (2016). RAS signalling through PI3-Kinase controls cell migration via modulation of Reelin expression. Nature Communications. 7(1). 11245–11245. 53 indexed citations

Godin-Heymann, Nadia, Sebastian Brabetz, Miguel Murillo, et al.. (2015). Tumour-suppression function of KLF12 through regulation of anoikis. Oncogene. 35(25). 3324–3334. 32 indexed citations

10.

Murillo, Miguel, Santiago Zelenay, Emma Nye, et al.. (2014). RAS interaction with PI3K p110α is required for tumor-induced angiogenesis. Journal of Clinical Investigation. 124(8). 3601–3611. 66 indexed citations

11.

Castellano, Esther, Clare Sheridan, May Zaw Thin, et al.. (2013). Requirement for Interaction of PI3-Kinase p110α with RAS in Lung Tumor Maintenance. Cancer Cell. 24(5). 617–630. 139 indexed citations

12.

Sheridan, Clare, Esther Castellano, May Zaw Thin, et al.. (2013). Abstract A54: Requirement for interaction of PI 3-kinase p110alpha with Ras in lung tumor maintenance. Cancer Research. 73(19_Supplement). A54–A54. 5 indexed citations

13.

Castellano, Esther & Eugenio Santos. (2011). Functional Specificity of Ras Isoforms: So Similar but So Different. Genes & Cancer. 2(3). 216–231. 211 indexed citations

14.

Castellano, Esther & Julian Downward. (2011). RAS Interaction with PI3K: More Than Just Another Effector Pathway. Genes & Cancer. 2(3). 261–274. 549 indexed citations breakdown →

15.

Iborra, Salvador, Manuel Soto, Luiz Stark Aroeira, et al.. (2011). H-ras and N-ras are dispensable for T-cell development and activation but critical for protective Th1 immunity. Blood. 117(19). 5102–5111. 33 indexed citations

16.

Castellano, Esther & Julian Downward. (2010). Role of RAS in the Regulation of PI 3-Kinase. Current topics in microbiology and immunology. 346. 143–169. 98 indexed citations

17.

Drosten, Matthias, Eleanor Y. M. Sum, Jelena Urosevic, et al.. (2010). Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival. The EMBO Journal. 29(6). 1091–1104. 243 indexed citations

18.

Castellano, Esther, Carmen Guerrero, Alejandro Núñez, Javier De Las Rivas, & Eugenio Santos. (2009). Serum-dependent transcriptional networks identify distinct functional roles for H-Ras and N-Ras during initial stages of the cell cycle. Genome biology. 10(11). R123–R123. 15 indexed citations

19.

Castellano, Esther, et al.. (2006). Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl. Experimental Cell Research. 312(6). 938–948. 35 indexed citations

20.

Castellano, Esther, Javier De Las Rivas, Carmen Guerrero, & Eugenio Santos. (2006). Transcriptional networks of knockout cell lines identify functional specificities of H-Ras and N-Ras: significant involvement of N-Ras in biotic and defense responses. Oncogene. 26(6). 917–933. 32 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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