Eefjan Breukink

14.1k citations

160 papers · 10.9k indexed · 3 hit papers · h-index 58

Impact in

Microbiology top 0.05%
- Antimicrobial Peptides and Activities
Molecular Medicine top 0.2%
- Antibiotic Resistance in Bacteria

Papers in

Microbiology 39
- Antimicrobial Peptides and Activities 36
Molecular Medicine 11

Co-authors: Ben de Kruijff Oscar P. Kuipers Cindy van Kraaij Waldemar Vollmer Hans‐Georg Sahl R.A. Demel I. Wiedemann Gabriele Bierbaum
Journals: Journal of Biological Chemistry (16 papers)Biochemistry (15 papers)Biochimica et Biophysica Acta (BBA) - Biomembranes (7 papers)ChemBioChem (6 papers)Molecular Microbiology (5 papers)
Partner nations: Netherlands United Kingdom France

In The Last Decade

Eefjan Breukink

159 papers receiving 10.6k citations

Hit Papers

align trajectories log scale

Lipid II as a target for antibiotics 2006 · 553 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2006 Nature Reviews Drug Discovery
2001 Journal of Biological Chemistry
1999 Science

Peers

Countries citing papers authored by Eefjan Breukink

Since Specialization

Citations

This map shows the geographic impact of Eefjan Breukink's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eefjan Breukink with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eefjan Breukink more than expected).

Fields of papers citing papers by Eefjan Breukink

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eefjan Breukink. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eefjan Breukink. The network helps show where Eefjan Breukink may publish in the future.

Co-authors

The 25 scholars most cited alongside Eefjan Breukink, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Eefjan Breukink Line = papers co-authored together Eefjan Breukink links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The enigmatic mode of action of the lantibiotic epilancin 15X Biochimica et Biophysica Acta (BBA) - Biomembranes ·Xiaoqi Wang, Yang Xu, Nathaniel I. Martin, Eefjan Breukink	2024	4
2	Outer membrane lipoprotein NlpI scaffolds peptidoglycan hydrolases within multi‐enzyme complexes in Escherichia coli The EMBO Journal ·Manuel Banzhaf, Hamish C. L. Yau, Jolanda Verheul, Adam Lodge, George Kritikos, André Mateus, Baptiste Cordier, Ann Kristin Hov, Frank Stein, Morgane Wartel, Manuel Pazos, Alexandra S. Solovyova, Eefjan Breukink, Sven van Teeffelen, Mikhail M. Savitski, Tanneke den Blaauwen, Athanasios Typas, Waldemar Vollmer	2020	63
3	The bacterial cell division protein fragment EFtsN binds to and activates the major peptidoglycan synthase PBP1b Journal of Biological Chemistry ·Adrien Boes, Frédéric Kerff, R. Herman, Thierry Touzé, Eefjan Breukink, Mohammed Terrak	2020	13
4	Peptidoglycan Remodeling Enables Escherichia coli To Survive Severe Outer Membrane Assembly Defect mBio ·N. K. More, Alessandra M. Martorana, Jacob Biboy, Christian Otten, Matthias Winkle, Carlos K. Gurnani Serrano, Alejandro Montón Silva, Lisa Atkinson, Hamish C. L. Yau, Eefjan Breukink, Tanneke den Blaauwen, Waldemar Vollmer, Alessandra Polissi	2019	118
5	Regulation of the Peptidoglycan Polymerase Activity of PBP1b by Antagonist Actions of the Core Divisome Proteins FtsBLQ and FtsN mBio ·Adrien Boes, Samir Olatunji, Eefjan Breukink, Mohammed Terrak	2019	58
6	Mechanisms of Incorporation for D-Amino Acid Probes That Target Peptidoglycan Biosynthesis ACS Chemical Biology ·Erkin Kuru, Atanas Radkov, Xin Meng, Alexander J. F. Egan, Laura Álvarez, Mandy Dowson-Day, Garrett Booher, Eefjan Breukink, David I. Roper, Felipe Cava, Waldemar Vollmer, Yves V. Brun, Michael S. VanNieuwenhze	2019	107
7	The Fluorescent D-Amino Acid NADA as a Tool to Study the Conditional Activity of Transpeptidases in Escherichia coli Frontiers in Microbiology ·Alejandro Montón Silva, Christian Otten, Jacob Biboy, Eefjan Breukink, Michael S. VanNieuwenhze, Waldemar Vollmer, Tanneke den Blaauwen	2018	18
8	Site‐Specific Immobilization of the Peptidoglycan Synthase PBP1B on a Surface Plasmon Resonance Chip Surface ChemBioChem ·Inge L. van't Veer, Nadia Leloup, Alexander J. F. Egan, B.J.C. Janssen, Nathaniel I. Martin, Waldemar Vollmer, Eefjan Breukink	2016	13
9	Antibacterial photodynamic therapy: overview of a promising approach to fight antibiotic-resistant bacterial infections Journal of Clinical and Translational Research ·Yao Liu, Rong Qin, Sebastian A. J. Zaat, Eefjan Breukink, Michal Heger	2015	271
10	In vitro Reconstitution of Peptidoglycan Assembly from the Gram-Positive Pathogen Streptococcus pneumoniae ACS Chemical Biology ·André Zapun, Jules Philippe, Katherine A. Abrahams, Luca Signor, David I. Roper, Eefjan Breukink, Thierry Vernet	2013	59
11	Turning Defense into Offense: Defensin Mimetics as Novel Antibiotics Targeting Lipid II PLoS Pathogens ·Kristen M. Varney, Alexandre M. J. J. Bonvin, Marzena Pazgier, Jakob J Malin, Wenbo Yu, Eugene N. Ateh, Taiji Oashi, Wuyuan Lu, Jing Huang, Marlies Diepeveen-de Buin, Joseph Bryant, Eefjan Breukink, Alexander D. MacKerell, Erik P. H. de Leeuw	2013	50
12	Calcium-Dependent Complex Formation Between PBP2 and Lytic Transglycosylase SltB1 of Pseudomonas aeruginosa Microbial Drug Resistance ·Ioulia Nikolaidis, Thierry Izoré, Viviana Job, Nicole M. Thielens, Eefjan Breukink, Andréa Dessen	2012	23
13	Reduction of Clostridium sporogenes spore outgrowth in natural sausage casings using nisin Food Microbiology ·Joris J. Wijnker, Erik A. W. S. Weerts, Eefjan Breukink, J.H. Houben, Len J.A. Lipman	2011	34
14	Functional interaction of human neutrophil peptide‐1 with the cell wall precursor lipid II FEBS Letters ·Erik de Leeuw, Changqing Li, Pengyun Zeng, Chong Li, Marlies Diepeveen-de Buin, Weiyue Lu, (unknown), Eefjan Breukink, Wuyuan Lu	2010	183
15	Regulation of Peptidoglycan Synthesis by Outer-Membrane Proteins Cell ·Athanasios Typas, Manuel Banzhaf, H. Bart van den Berg van Saparoea, Jolanda Verheul, Jacob Biboy, Robert J. Nichols, Matylda Zietek, Katrin Beilharz, Kai Kannenberg, Moritz von Rechenberg, Eefjan Breukink, Tanneke den Blaauwen, Carol A. Gross, Waldemar Vollmer	2010	293
16	Specific Labeling of Peptidoglycan Precursors as a Tool for Bacterial Cell Wall Studies ChemBioChem ·Vincent van Dam, Nick K. Olrichs, Eefjan Breukink	2009	29
17	Natamycin Blocks Fungal Growth by Binding Specifically to Ergosterol without Permeabilizing the Membrane Journal of Biological Chemistry ·Yvonne M. te Welscher, Hendrik H. ten Napel, Miriam Masià Balagué, Cleiton Martins Souza, Howard Riezman, Ben de Kruijff, Eefjan Breukink	2007	200
18	Lipid II as a target for antibiotics Nature Reviews Drug Discovery ·Eefjan Breukink, Ben de Kruijff Hit paper breakdown →	2006	553
19	Specific interaction of the lantibiotic nisin with lipid II leads to highly efficient pore formation Biophysical Journal ·Eefjan Breukink, Boyan B. Bonev, I. Wiedemann, Hans‐Georg SAHL, Alan G. Watts, Ben de Kruijff	2001	5
20	Influence of the Signal Sequence and Chaperone SecB on the Interaction between Precursor Protein prePhoE and Phospholipids European Journal of Biochemistry ·Anne L. J. Van Raalte, R.A. Demel, Geerten Verberkmoes, Eefjan Breukink, Rob C. A. Keller, Ben de Kruijff	1996	7

About Eefjan Breukink

Eefjan Breukink is a scholar working on Microbiology, Molecular Medicine, Genetics, Food Science and Molecular Biology, having authored 160 papers that have together received 10.9k indexed citations. Recurring topics across this work include Bacterial Genetics and Biotechnology (57 papers), Bacteriophages and microbial interactions (37 papers), Antimicrobial Peptides and Activities (36 papers), Probiotics and Fermented Foods (35 papers), Biochemical and Structural Characterization (27 papers), RNA and protein synthesis mechanisms (21 papers), Lipid Membrane Structure and Behavior (20 papers) and Glycosylation and Glycoproteins Research (19 papers). The work is most often cited by research in Microbiology (2.6k citations), Molecular Medicine (1.1k citations), Food Science (2.9k citations), Molecular Biology (6.7k citations) and Genetics (2.7k citations). Eefjan Breukink has collaborated with scholars based in Netherlands, United Kingdom and France. Frequent co-authors include Ben de Kruijff, Oscar P. Kuipers, Cindy van Kraaij, Waldemar Vollmer, Hans‐Georg Sahl, R.A. Demel, Ben de Kruijff, I. Wiedemann, Gabriele Bierbaum and Alexandre M. J. J. Bonvin. Their work appears in journals such as Journal of Biological Chemistry, Biochemistry, Biochimica et Biophysica Acta (BBA) - Biomembranes, ChemBioChem and Molecular Microbiology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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