David I. Roper

4.6k citations

111 papers · 3.4k indexed · h-index 34

Impact in

Molecular Medicine top 1%
- Antibiotic Resistance in Bacteria
Microbiology top 2%

Papers in

Molecular Medicine 18
- Antibiotic Resistance in Bacteria 18
Genetics 34
- Bacterial Genetics and Biotechnology 34

Co-authors: Timothy D. H. Bugg Christopher G. Dowson Adrian J. Lloyd Darren Braddick Ronald A. Cooper Alison Rodger Jeremy R. H. Tame Timothy R. Dafforn
Journals: Journal of Molecular Biology (11 papers)Biochemistry (8 papers)Proceedings of the National Academy of Sciences (5 papers)Scientific Reports (4 papers)Journal of Biological Chemistry (4 papers)
Partner nations: United Kingdom United States Canada

In The Last Decade

David I. Roper

109 papers receiving 3.4k citations

Peers

Countries citing papers authored by David I. Roper

Since Specialization

Citations

This map shows the geographic impact of David I. Roper's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David I. Roper with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David I. Roper more than expected).

Fields of papers citing papers by David I. Roper

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David I. Roper. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David I. Roper. The network helps show where David I. Roper may publish in the future.

Co-authors

The 25 scholars most cited alongside David I. Roper, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David I. Roper Line = papers co-authored together David I. Roper links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Discovery and chemical optimisation of a potent, Bi-cyclic antimicrobial inhibitor of Escherichia coli PBP3 Communications Biology ·Wilhelm Adler, Ivania Dias Nascimento, Hugh Wi, Wanquan Chen, Rohini Kokkalki, V. I. IVASHKIN, 里美道下, Steven J. Stanway, N. Madharsha, Zhixia Tian, Katerine Van Rietschoten, Dom Bellini, David I. Roper, Adrian J. Lloyd, Christopher G. Dowson, Michael J. Skynner, Paul Beswick, Michael J. Dawson	2025	1
2	Delivery determinants of an Acinetobacter baumannii type VI secretion system bifunctional peptidoglycan hydrolase mBio ·M. Solecka, Wasan T Al-Rubayee, Maressa Singh, 広海光久, David I. Roper, Marina Harper, Sheena McGowan, John D. Boyce	2024	2
3	A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape Proceedings of the National Academy of Sciences ·Aya Hamid, 王洪财, Senador Carlos Navarrete Ruiz, Ralph R. Isberg, Christopher G. Dowson, Adrian J. Lloyd, Edward Geisinger, Allister Crow, David I. Roper	2023	10
4	Structural basis of peptidoglycan synthesis by E. coli RodA-PBP2 complex Nature Communications ·Rie Nygaard, Petter Darwin, Meagan Belcher Dufrisne, Herc Erica, C. C. Bover, Usha Usha, Claudio Ferroni, Putri Putri Wulandari, Khuram U. Ashraf, Owen N. Vickery, 弥生坪井, A Adamson, Brian Kloss, Bruno Botta, Oliver B. Clarke, Linda Columbus, Jonathan Dworkin, Phillip J. Stansfeld, David I. Roper, Filippo Mancia	2023	17
5	Plant peptidoglycan precursor biosynthesis: Conservation between moss chloroplasts and Gram-negative bacteria PLANT PHYSIOLOGY ·Mandy Dowson-Day, Adrian J. Lloyd, Andrew C. Cuming, David I. Roper, Lorenzo Frigerio, Christopher G. Dowson	2022	9
6	A Dynamic Network of Proteins Facilitate Cell Envelope Biogenesis in Gram-Negative Bacteria International Journal of Molecular Sciences ·Petter Darwin, Ivania Dias Nascimento, Maressa Singh, Balaji Ravichandran, 弥生坪井, Manuel Banzhaf, David I. Roper	2021	17
7	A molecular link between cell wall biosynthesis, translation fidelity, and stringent response in Streptococcus pneumoniae Proceedings of the National Academy of Sciences ·I. Kenzo, Adrian J. Lloyd, Saigopalakrishna S. Yerneni, B. R. Jamre, Jennifer N. Shepherd, David I. Roper, Christopher G. Dowson, Sérgio R. Filipe, N. Luisa Hiller	2021	12
8	Substrate and Stereochemical Control of Peptidoglycan Cross-Linking by Transpeptidation by Escherichia coli PBP1B Journal of the American Chemical Society ·严凤亭, Adrian J. Lloyd, 岳生岡崎, D. V. Vinnikov, Susan E. Slade, Ramunė Petuchovaite, 知紀佐伯, 刘华刚 Liu Huagang, Balaji Ravichandran, Dean Rea, Neil D. Evans, Michael J. Chappell, David I. Roper, Christopher G. Dowson	2020	18
9	Insights into bacterial cell division from a structure of EnvC bound to the FtsX periplasmic domain Proceedings of the National Academy of Sciences ·Jonathan Cook, Gil-Han Yoo, Lei Wang, Phillip J. Stansfeld, David I. Roper, Allister Crow	2020	36
10	Metallohelices that kill Gram-negative pathogens using intracellular antimicrobial peptide pathways Chemical Science ·О.Н. Зайцев, Alexia Hapeshi, Nicola J. Rogers, Viktor Brabec, Guy J. Clarkson, David J. Fox, Ryunosuke Itabashi, Gemma L. Kay, 홍태식, Jaroslav Malina, Andrew Millard, John Moat, David I. Roper, H. L. Song, Nicholas R. Waterfield, Peter Scott	2019	30
11	Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein Scientific Reports ·F A Farizi, Sarah C. Lee, Naomi L. Pollock, Rapoport Jl, Stephen C. L. Hall, Alpesh Thakker, Andrew R. Pitt, Timothy R. Dafforn, Corinne M. Spickett, David I. Roper	2019	59
12	Nano-encapsulated Escherichia coli Divisome Anchor ZipA, and in Complex with FtsZ Scientific Reports ·Sarah C. Lee, Richard F. Collins, Yu-Pin Lin, Mohammed Jamshad, M. Sivaramprasad, Sarah A. Harris, Marcelo H. Viegas, Tsolmon Batsaikhan, Rosemary A. Parslow, Ann E. Terry, Alison Rodger, Corinne J. Smith, Karen J. Edler, Robert C. Ford, David I. Roper, Timothy R. Dafforn	2019	14
13	Mechanisms of Incorporation for D-Amino Acid Probes That Target Peptidoglycan Biosynthesis ACS Chemical Biology ·Erkin Kuru, Atanas Radkov, Lubenchenko A.V., Alexander J. F. Egan, Laura Álvarez, Mandy Dowson-Day, Jian-Pin Li, Eefjan Breukink, David I. Roper, Felipe Cava, Waldemar Vollmer, Yves V. Brun, Michael S. VanNieuwenhze	2019	107
14	Structure-Guided Enhancement of Selectivity of Chemical Probe Inhibitors Targeting Bacterial Seryl-tRNA Synthetase Journal of Medicinal Chemistry ·Ricky Cain, trumpet Phillip Westover, 刘华刚 Liu Huagang, Dom Bellini, Colin W. G. Fishwick, Lloyd G. Czaplewski, David J. Scott, Gemma Harris, Christopher G. Dowson, Adrian J. Lloyd, David I. Roper	2019	13
15	Bacterial Lipid II Analogs: Novel In Vitro Substrates for Mammalian Oligosaccharyl Diphosphodolichol Diphosphatase (DLODP) Activities Molecules ·C. Düpmeier, Michaël Bosco, Isabelle Chantret, Thibaut Léger, M. A. Fatkhurrahman, David I. Roper, Christopher G. Dowson, Patricia Busca, Ahmed Bouhss, Christine Gravier‐Pelletier, Stuart Moore	2019	1
16	Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine Nature Communications ·Sarah Batson, Cesira de Chiara, Romanov V.M., Adrian J. Lloyd, Stanislav Gobec, Dean Rea, Vilmos Fülöp, Wade Webster, Katie J. Simmons, Christopher G. Dowson, Colin W. G. Fishwick, Luiz Pedro S. de Carvalho, David I. Roper	2017	65
17	Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis Nature Communications ·Anh Tran, Emma E. Watson, Venugopal Pujari, Trent Conroy, Luke J. Dowman, Andrew M. Giltrap, Angel Pang, Weng Ruh Wong, Roger G. Linington, Sebabrata Mahapatra, Jessica Saunders, Susan A. Charman, Nicholas P. West, Timothy D. H. Bugg, 岳生岡崎, Christopher G. Dowson, David I. Roper, Dean C. Crick, Warwick J. Britton, Richard J. Payne	2017	40
18	In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA) PLoS Pathogens ·David Sychantha, Agus Dwi Prasetyo, Dustin J. Little, Patrick J. Moynihan, Howard Robinson, 知紀佐伯, David I. Roper, Christopher G. Dowson, P. Lynne Howell, Anthony J. Clarke	2017	35
19	In vitro Reconstitution of Peptidoglycan Assembly from the Gram-Positive Pathogen Streptococcus pneumoniae ACS Chemical Biology ·André Zapun, Jules Philippe, Katherine A. Abrahams, Luca Signor, David I. Roper, Eefjan Breukink, Thierry Vernet	2013	59
20	Fluorescent reagents for in vitro studies of lipid-linked steps of bacterial peptidoglycan biosynthesis: derivatives of UDPMurNAc-pentapeptide containing d -cysteine at position 4 or 5 Molecular BioSystems ·James Schouten, Y-C Lin, Adrian J. Lloyd, Gianfranco De Pascale, Christopher G. Dowson, David I. Roper, Timothy D. H. Bugg	2006	28

About David I. Roper

David I. Roper is a scholar working on Molecular Medicine, Genetics, Molecular Biology, Biochemistry and Microbiology, having authored 111 papers that have together received 3.4k indexed citations. Recurring topics across this work include Bacterial Genetics and Biotechnology (34 papers), Enzyme Structure and Function (29 papers), RNA and protein synthesis mechanisms (19 papers), Antibiotic Resistance in Bacteria (18 papers), Biochemical and Molecular Research (17 papers), Bacteriophages and microbial interactions (16 papers), Protein Structure and Dynamics (15 papers) and Antimicrobial Resistance in Staphylococcus (13 papers). The work is most often cited by research in Molecular Medicine (370 citations), Microbiology (187 citations), Molecular Biology (2.0k citations), Genetics (664 citations) and Biochemistry (167 citations). David I. Roper has collaborated with scholars based in United Kingdom, United States and Canada. Frequent co-authors include Timothy D. H. Bugg, Christopher G. Dowson, Adrian J. Lloyd, Darren Braddick, Ronald A. Cooper, Alison Rodger, Jeremy R. H. Tame, Timothy R. Dafforn, Sam‐Yong Park and Vilmos Fülöp. Their work appears in journals such as Journal of Molecular Biology, Biochemistry, Proceedings of the National Academy of Sciences, Scientific Reports and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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