Edwin Klein

8.7k citations

83 papers · 5.4k indexed · 1 hit paper · h-index 36

Impact in

Infectious Diseases top 0.2%
- Tuberculosis Research and Epidemiology
Immunology top 2%
- Immune Cell Function and Interaction
- Immune responses and vaccinations
- Immunodeficiency and Autoimmune Disorders

Papers in ⓘ

Infectious Diseases 32
- Tuberculosis Research and Epidemiology 28
Surgery 39
- Infectious Diseases and Tuberculosis 18
- Xenotransplantation and immune response 11

Co-authors: JoAnne L. Flynn (27 shared papers)Philana Ling Lin (23 shared papers)Natalya V. Serbina (2 shared papers)Saverio Capuano (6 shared papers)Carl R. Fuhrman (5 shared papers)Amy Myers (5 shared papers)Clifton E. Barry (5 shared papers)Santosh Pawar (3 shared papers)
Journals: Infection and Immunity (7 papers)Xenotransplantation (4 papers)The Journal of Immunology (3 papers)Critical Care Medicine (3 papers)PLoS Pathogens (3 papers)
Partner nations: United States China Italy

In The Last Decade

Edwin Klein

81 papers receiving 5.3k citations

Hit Papers

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Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates 2008 · 498 citations

Peers

Countries citing papers authored by Edwin Klein

Since Specialization

Citations

This map shows the geographic impact of Edwin Klein's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edwin Klein with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edwin Klein more than expected).

Fields of papers citing papers by Edwin Klein

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edwin Klein. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edwin Klein. The network helps show where Edwin Klein may publish in the future.

Co-authors

The 25 scholars most cited alongside Edwin Klein, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Edwin Klein Line = papers co-authored together Edwin Klein links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 83 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates Infection and Immunity ·Laura E. Via, Philana Ling Lin, Sonja M. Ray, José Carrillo, Shannon Sedberry Allen, Seok Yong Eum, Kimberly L. Taylor, Edwin Klein, Ujjini H. Manjunatha, Jacqueline Gonzales, Eun Gae Lee, Seung Kyu Park, James A. Raleigh, Sang Nae Cho, David N. McMurray, JoAnne L. Flynn, Clifton E. Barry Hit paper breakdown →	2008	498
2	Mice deficient in CD4 T cells have only transiently diminished levels of IFN-gamma, yet succumb to tuberculosis. PubMed ·Amy Myers Caruso, Natalya V. Serbina, Edwin Klein, K J Triebold, B R Bloom, JoAnne L. Flynn	1999	396
3	Mice Deficient in CD4 T Cells Have Only Transiently Diminished Levels of IFN-γ, Yet Succumb to Tuberculosis The Journal of Immunology ·Amy Myers Caruso, Natalya V. Serbina, Edwin Klein, K J Triebold, Barry R. Bloom, JoAnne L. Flynn	1999	363
4	ExperimentalMycobacterium tuberculosisInfection of Cynomolgus Macaques Closely Resembles the Various Manifestations of HumanM. tuberculosisInfection Infection and Immunity ·Saverio Capuano, Denise A. Croix, Santosh Pawar, Angelica Zinovik, Amy Myers, Philana Ling Lin, Stephanie J. Bissel, Carl R. Fuhrman, Edwin Klein, JoAnne L. Flynn	2003	351
5	Quantitative Comparison of Active and Latent Tuberculosis in the Cynomolgus Macaque Model Infection and Immunity ·Philana Ling Lin, Mark Rodgers, Le'Kneitah P. Smith, Matthew Bigbee, Amy Myers, Carolyn Bigbee, Ion Chiosea, Saverio Capuano, Carl R. Fuhrman, Edwin Klein, JoAnne L. Flynn	2009	312
6	Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms The Journal of Immunology ·Joshua T. Mattila, Olabisi Ojo, Diane Kepka‐Lenhart, Simeone Marino, Jin Hee Kim, Seok Yong Eum, Laura E. Via, Clifton E. Barry, Edwin Klein, Denise E. Kirschner, Sidney M. Morris, Philana Ling Lin, JoAnne L. Flynn	2013	262
7	The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection Journal of Clinical Investigation ·Philana Ling Lin, Jes Dietrich, Esterlina V. Tan, Rodolfo M. Abalos, Jasmin Burgos, Carolyn Bigbee, Matthew Bigbee, Leslie Milk, Hannah P. Gideon, Mark Rodgers, Catherine Cochran, Kristi M. Guinn, David R. Sherman, Edwin Klein, Christopher Janssen, JoAnne L. Flynn, Peter Andersen	2011	200
8	Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model Arthritis & Rheumatism ·Philana Ling Lin, Amy Myers, Le'Kneitah P. Smith, Carolyn Bigbee, Matthew Bigbee, Carl R. Fuhrman, Heather Grieser, Ion Chiosea, Nikolai N. Voitenek, Saverio Capuano, Edwin Klein, JoAnne L. Flynn	2010	191
9	Early Events in Mycobacterium tuberculosis Infection in Cynomolgus Macaques Infection and Immunity ·Philana Ling Lin, Santosh Pawar, Amy Myers, Amarendra Pegu, Carl R. Fuhrman, Todd A. Reinhart, Saverio Capuano, Edwin Klein, JoAnne L. Flynn	2006	178
10	Pig kidney graft survival in a baboon for 136 days: longest life‐supporting organ graft survival to date Xenotransplantation ·Hayato Iwase, Hong Liu, Martin Wijkstrom, Huidong Zhou, Jagjit Singh, Hidetaka Hara, Mohamed Ezzelarab, Cassandra Long, Edwin Klein, Robert A. Wagner, Carol J. Phelps, David Ayares, Ron Shapiro, Abhinav Humar, David K. C. Cooper	2015	170
11	Immunological and physiological observations in baboons with life‐supporting genetically engineered pig kidney grafts Xenotransplantation ·Hayato Iwase, Hidetaka Hara, Mohamed Ezzelarab, Tao Li, Zhongqiang Zhang, Bingsi Gao, Hong Liu, Cassandra Long, Yi Wang, Amy Cassano, Edwin Klein, Carol J. Phelps, David Ayares, Abhinav Humar, Martin Wijkstrom, David K. C. Cooper	2017	163
12	Radiologic Responses in Cynomolgus Macaques for Assessing Tuberculosis Chemotherapy Regimens Antimicrobial Agents and Chemotherapy ·Philana Ling Lin, Teresa Coleman, Jonathan Carney, Brian J. Lopresti, Jaime Tomko, Dan Fillmore, Véronique Dartois, Charles A. Scanga, L. James Frye, Christopher Janssen, Edwin Klein, Clifton E. Barry, JoAnne L. Flynn	2013	129
13	Reactivation of Latent Tuberculosis in Cynomolgus Macaques Infected with SIV Is Associated with Early Peripheral T Cell Depletion and Not Virus Load PLoS ONE ·Collin R. Diedrich, Joshua T. Mattila, Edwin Klein, Chris Janssen, Jia Yao Phuah, Timothy J. Sturgeon, Ronald C. Montelaro, Philana Ling Lin, JoAnne L. Flynn	2010	125
14	CD4 T Cell Depletion Exacerbates Acute Mycobacterium tuberculosis While Reactivation of Latent Infection Is Dependent on Severity of Tissue Depletion in Cynomolgus Macaques AIDS Research and Human Retroviruses ·Philana Ling Lin, Tara Rutledge, Angela M. Green, Matthew Bigbee, Carl R. Fuhrman, Edwin Klein, JoAnne L. Flynn	2012	105
15	Impact of Thrombocytopenia on Survival of Baboons with Genetically Modified Pig Liver Transplants: Clinical Relevance American Journal of Transplantation ·Burcin Ekser, Cassandra Long, Gabriel J. Echeverri, Hidetaka Hara, Mohamed Ezzelarab, C.-C. Lin, Michael E. de Vera, Robert A. Wagner, Edwin Klein, Roman F. Wolf, David Ayares, David K. C. Cooper, Bruno Gridelli	2009	104
16	Early Changes by ¹⁸ Fluorodeoxyglucose Positron Emission Tomography Coregistered with Computed Tomography Predict Outcome after Mycobacterium tuberculosis Infection in Cynomolgus Macaques Infection and Immunity ·M. Teresa Coleman, Pauline Maiello, Jaime Tomko, L. James Frye, Daniel Fillmore, Christopher Janssen, Edwin Klein, Philana Ling Lin	2014	100
17	PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis Science Translational Medicine ·M. Teresa Coleman, Ray Y. Chen, Myungsun Lee, Philana Ling Lin, Lori E. Dodd, Pauline Maiello, Laura E. Via, Youngran Kim, Gwendolyn A. Marriner, Véronique Dartois, Charles A. Scanga, Christopher Janssen, Jing Wang, Edwin Klein, Sang Nae Cho, Clifton E. Barry, JoAnne L. Flynn	2014	94
18	Non-human primates: a model for tuberculosis research Tuberculosis ·JoAnne L. Flynn, Saverio Capuano, Denise A. Croix, Santosh Pawar, Anna Myers, Angelica Zinovik, Edwin Klein	2003	93
19	Metronidazole prevents reactivation of latentMycobacterium tuberculosisinfection in macaques Proceedings of the National Academy of Sciences ·Philana Ling Lin, Véronique Dartois, Paul Johnston, Christopher Janssen, Laura E. Via, Michael Goodwin, Edwin Klein, Clifton E. Barry, JoAnne L. Flynn	2012	90
20	PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis PLoS Pathogens ·Philana Ling Lin, Pauline Maiello, Hannah P. Gideon, M. Teresa Coleman, Anthony M. Cadena, Mark Rodgers, Robert W. Gregg, Melanie O’Malley, Jaime Tomko, Daniel Fillmore, L. James Frye, Tara Rutledge, Robert M. DiFazio, Christopher Janssen, Edwin Klein, Peter Andersen, Sarah M. Fortune, JoAnne L. Flynn	2016	89

About Edwin Klein

Edwin Klein is a scholar working on Infectious Diseases, Surgery, Epidemiology, Critical Care and Intensive Care Medicine and Emergency Medicine, having authored 83 papers that have together received 5.4k indexed citations. Recurring topics across this work include Tuberculosis Research and Epidemiology (28 papers), Mycobacterium research and diagnosis (24 papers), Infectious Diseases and Tuberculosis (18 papers), Xenotransplantation and immune response (11 papers), Immune Cell Function and Interaction (6 papers), Cardiac Arrest and Resuscitation (6 papers), Animal Genetics and Reproduction (6 papers) and Virus-based gene therapy research (4 papers). The work is most often cited by research in Infectious Diseases (3.2k citations), Immunology (1.5k citations), Epidemiology (2.3k citations), Surgery (1.8k citations) and Virology (181 citations). Edwin Klein has collaborated with scholars based in United States, China and Italy. Frequent co-authors include JoAnne L. Flynn, Philana Ling Lin, Natalya V. Serbina, Saverio Capuano, Carl R. Fuhrman, Amy Myers, Clifton E. Barry, Santosh Pawar, B R Bloom and Laura E. Via. Their work appears in journals such as Infection and Immunity, Xenotransplantation, The Journal of Immunology, Critical Care Medicine and PLoS Pathogens.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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