David Ayares

15.6k total citations · 4 hit papers
243 papers, 9.0k citations indexed

About

David Ayares is a scholar working on Surgery, Genetics and Molecular Biology. According to data from OpenAlex, David Ayares has authored 243 papers receiving a total of 9.0k indexed citations (citations by other indexed papers that have themselves been cited), including 215 papers in Surgery, 139 papers in Genetics and 57 papers in Molecular Biology. Recurrent topics in David Ayares's work include Xenotransplantation and immune response (211 papers), Animal Genetics and Reproduction (89 papers) and Virus-based gene therapy research (65 papers). David Ayares is often cited by papers focused on Xenotransplantation and immune response (211 papers), Animal Genetics and Reproduction (89 papers) and Virus-based gene therapy research (65 papers). David Ayares collaborates with scholars based in United States, China and Germany. David Ayares's co-authors include David K. C. Cooper, Hidetaka Hara, Mohamed Ezzelarab, Suyapa Ball, Carol J. Phelps, Cassandra Long, Todd Vaught, Yifan Dai, Hayato Iwase and Jeremy Boone and has published in prestigious journals such as Nature, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

David Ayares

235 papers receiving 8.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cloned pigs produced by nuclear transfer from adult somatic cells

2000 955 citations Todd Vaught, Raymond Page et al. profile →
Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs

2002 576 citations Todd Vaught, Jeremy Boone et al. profile →
Genetically Modified Porcine-to-Human Cardiac Xenotransplantation

2022 365 citations Bartley P. Griffith, Corbin E. Goerlich et al. New England Journal of Medicine profile →
Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

2016 330 citations Muhammad M. Mohiuddin, Avneesh K. Singh et al. profile →

Peers

Countries citing papers authored by David Ayares

Since Specialization

Citations

This map shows the geographic impact of David Ayares's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Ayares with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Ayares more than expected).

Fields of papers citing papers by David Ayares

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Ayares. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Ayares. The network helps show where David Ayares may publish in the future.

Co-authorship network of co-authors of David Ayares

This figure shows the co-authorship network connecting the top 25 collaborators of David Ayares. A scholar is included among the top collaborators of David Ayares based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David Ayares. David Ayares is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Genetically engineered pig heart transplantation in non-human primates 2025 ·Communications Medicine ·Avneesh K. Singh, Corbin E. Goerlich, Tianshu Zhang, Billeta Lewis, Alena Hershfeld, Gheorghe Braileanu, (unknown), Kathryn Rice, Faith Sentz, Sarah R. Mudd, Patrick Odonkor, Erik Strauss, Brittney Williams, Allen Burke, Anuj Gupta, Cinthia B. Drachenberg, David Ayares, Bartley P. Griffith, Muhammad M. Mohiuddin	5
2	Novel factors potentially initiating acute antibody‐mediated rejection in pig kidney xenografts despite an efficient immunosuppressive regimen 2024 ·Xenotransplantation ·(unknown), (unknown), Ivy A. Rosales, Ahmad Karadagi, Toshihide Tomosugi, David Ayares, Seth Lederman, Robert B. Colvin, Tatsuo Kawai, Richard N. Pierson, Takaaki Kobayashi, David K. C. Cooper	8
3	Physiological basis for xenotransplantation from genetically modified pigs to humans 2024 ·Physiological Reviews ·Leigh Peterson, Magdi H. Yacoub, David Ayares, Kazuhiko Yamada, Daniel Eisenson, Bartley P. Griffith, Muhammad M. Mohiuddin, W.H. Eyestone, J. Craig Venter, Ryszard T. Smoleński, Martine Rothblatt	18
4	Renin-angiotensin-aldosterone system function in the pig-to-baboon kidney xenotransplantation model 2023 ·American Journal of Transplantation ·Christophe Hansen‐Estruch, Mohamed H. Bikhet, (unknown), Akemi Katsurada, Ryousuke Satou, Weijian Shao, David Ayares, Raman Venkataramanan, David K. C. Cooper, Eric Judd, L. Gabriel Navar	17
5	De novo membranous nephropathy in a pig-to-baboon kidney xenograft: A new xenograft glomerulopathy 2023 ·American Journal of Transplantation ·Ivy A. Rosales, (unknown), (unknown), (unknown), Martin K. Selig, (unknown), A. Bernard Collins, David Ayares, David K.C. Cooper, Robert B. Colvin	6
6	The road to the first FDA‐approved genetically engineered pig heart transplantation into human 2022 ·Xenotransplantation ·Avneesh K. Singh, Bartley P. Griffith, Corbin E. Goerlich, David Ayares, Muhammad M. Mohiuddin	7
7	Genetically Modified Porcine-to-Human Cardiac Xenotransplantation breakdown → 2022 ·New England Journal of Medicine ·Bartley P. Griffith, Corbin E. Goerlich, Avneesh K. Singh, Martine Rothblatt, Christine L. Lau, Aakash Shah, Marc I. Lorber, Alison Grazioli, Kapil Saharia, Susie N. Hong, Susan Joseph, David Ayares, Muhammad M. Mohiuddin	365
8	The growth of xenotransplanted hearts can be reduced with growth hormone receptor knockout pig donors 2021 ·Journal of Thoracic and Cardiovascular Surgery ·Corbin E. Goerlich, Bartley P. Griffith, Peter Hanna, Susie N. Hong, David Ayares, Avneesh K. Singh, Muhammad M. Mohiuddin	56
9	Evidence that sensitization to triple‐knockout pig cells will not be detrimental to subsequent allotransplantation 2021 ·Xenotransplantation ·Hidetaka Hara, (unknown), Zheng‐Yu Wang, Abhijit Jagdale, Mohamed H. Bikhet, Takayuki Yamamoto, Hayato Iwase, David Ayares, David K. C. Cooper	12
10	Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies 2020 ·Xenotransplantation ·Arne Hinrichs, (unknown), Nikolai Klymiuk, Andreas Blutke, Elisabeth Kemter, Matthias Längin, Maik Dahlhoff, Barbara Keßler, Mayuko Kurome, Valeri Zakhartchenko, (unknown), David Ayares, Martin Bidlingmaier, Florian Flenkenthaler, Martin Hrabě de Angelis, Georg J. Arnold, Bruno Reichart, Thomas Fröhlich, Eckhard Wolf	55
11	P‐ and E‐selectin receptor antagonism prevents human leukocyte adhesion to activated porcine endothelial monolayers and attenuates porcine endothelial damage 2018 ·Xenotransplantation ·Christopher Laird, (unknown), (unknown), (unknown), Xiangfei Cheng, William E. Fogler, John L. Magnani, Dawn Parsell, Arielle Cimeno, Carol J. Phelps, David Ayares, Lars Burdorf, Agnes M. Azimzadeh, Richard N. Pierson	19
12	Cardiac xenografts show reduced survival in the absence of transgenic human thrombomodulin expression in donor pigs 2018 ·Xenotransplantation ·Avneesh K. Singh, Joshua L. Chan, Laura DiChiacchio, (unknown), Philip C. Corcoran, Billeta Lewis, Marvin L. Thomas, Allen Burke, David Ayares, Keith A. Horvath, Muhammad M. Mohiuddin	49
13	Synthetic liver function is detectable in transgenic porcine livers perfused with human blood 2017 ·Xenotransplantation ·Arielle Cimeno, (unknown), (unknown), Carol J. Phelps, David Ayares, (unknown), Christopher Laird, Richard N. Pierson, Agnes M. Azimzadeh, Rolf N. Barth, John C. LaMattina	12
14	Transgenic expression of human leukocyte antigen‐E attenuates GalKO.hCD46 porcine lung xenograft injury 2017 ·Xenotransplantation ·Christopher Laird, Lars Burdorf, (unknown), (unknown), Xiangfei Cheng, Gheorghe Braileanu, Wenji Sun, (unknown), Arielle Cimeno, Dawn Parsell, Edward So, Andrea Bähr, Nikolai Klymiuk, Carol J. Phelps, David Ayares, Agnes M. Azimzadeh, Richard N. Pierson	36
15	Encouraging experience using multi‐transgenic xenografts in a pig‐to‐baboon cardiac xenotransplantation model 2017 ·Xenotransplantation ·Joshua L. Chan, Avneesh K. Singh, Philip C. Corcoran, Marvin L. Thomas, Billeta Lewis, David Ayares, Todd Vaught, Keith A. Horvath, Muhammad M. Mohiuddin	25
16	Abstract 14062: Cardiac Xenotransplantation-Associated Consumptive Thrombocytopenia is Attenuated With Use of Anti-CD40 Antibody Co-Stimulation Blockade 2016 ·Circulation ·Joshua L. Chan, Avneesh K. Singh, Marvin L. Thomas, David Ayares, Keith A. Horvath, Muhammad M. Mohiuddin	1
17	The role of genetically engineered pigs in xenotransplantation research 2016 ·PMC ·David K. C. Cooper, Burcin Ekser, Jagdeece Ramsoondar, Carol J. Phelps, David Ayares	2
18	Expression Levels of Growth-Regulating Imprinted Genes in Cloned Piglets 2007 ·Cloning and Stem Cells ·Le Jiang, (unknown), Liangxue Lai, Melissa Samuel, David Ayares, Randall S. Prather, Xiuchun Tian	24
19	Preimplantation Screening for Transgenesis Using an Embryonic Specific Promoter and Green Fluorescent Protein 2001 ·PubMed ·(unknown), (unknown), Amy S. Garst, Jeremy Boone, (unknown), Carol J. Phelps, David Ayares, Raymond Page	7
20	Repair of Single-Stranded DNA Nicks, Gaps, and Loops in Mammalian Cells 1987 ·Molecular and Cellular Biology ·David Ayares, Doina Ganea, Lavanya Chekuri, Colin Campbell, Raju Kucherlapati	13

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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