Denise E. Kirschner

15.6k total citations · 3 hit papers
170 papers, 11.3k citations indexed

About

Denise E. Kirschner is a scholar working on Infectious Diseases, Epidemiology and Immunology. According to data from OpenAlex, Denise E. Kirschner has authored 170 papers receiving a total of 11.3k indexed citations (citations by other indexed papers that have themselves been cited), including 88 papers in Infectious Diseases, 61 papers in Epidemiology and 51 papers in Immunology. Recurrent topics in Denise E. Kirschner's work include Tuberculosis Research and Epidemiology (80 papers), Mycobacterium research and diagnosis (44 papers) and HIV Research and Treatment (30 papers). Denise E. Kirschner is often cited by papers focused on Tuberculosis Research and Epidemiology (80 papers), Mycobacterium research and diagnosis (44 papers) and HIV Research and Treatment (30 papers). Denise E. Kirschner collaborates with scholars based in United States, France and Italy. Denise E. Kirschner's co-authors include Simeone Marino, J. Christian J. Ray, Ian B. Hogue, Jennifer J. Linderman, John C. Panetta, JoAnne L. Flynn, Alan S. Perelson, Rob J. de Boer, Glenn F. Webb and Martin J. Blaser and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nature Medicine.

In The Last Decade

Denise E. Kirschner

167 papers receiving 10.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A methodology for performing global uncertainty and sensitivity analysis in systems biology

2008 2.1k citations Simeone Marino, J. Christian J. Ray et al. Journal of Theoretical Biology profile →
Dynamics of HIV infection of CD4+ T cells

1993 740 citations Denise E. Kirschner et al. Mathematical Biosciences profile →
Modeling immunotherapy of the tumor - immune interaction

1998 678 citations Denise E. Kirschner et al. profile →

Peers

Countries citing papers authored by Denise E. Kirschner

Since Specialization

Citations

This map shows the geographic impact of Denise E. Kirschner's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Denise E. Kirschner with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Denise E. Kirschner more than expected).

Fields of papers citing papers by Denise E. Kirschner

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Denise E. Kirschner. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Denise E. Kirschner. The network helps show where Denise E. Kirschner may publish in the future.

Co-authorship network of co-authors of Denise E. Kirschner

This figure shows the co-authorship network connecting the top 25 collaborators of Denise E. Kirschner. A scholar is included among the top collaborators of Denise E. Kirschner based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Denise E. Kirschner. Denise E. Kirschner is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Forum on immune digital twins: a meeting report 2024 ·npj Systems Biology and Applications ·Reinhard Laubenbacher, (unknown), Gary An, Filippo Castiglione, Stephen Eubank, Luís L. Fonseca, James A. Glazier, Tomáš Helikar, (unknown), Denise E. Kirschner, Paul Macklin, Borna Mehrad, Bethany B. Moore, (unknown), Ilya Shmulevich, Amber M. Smith, Isabel Voigt, Thomas E. Yankeelov, Tjalf Ziemssen	6
2	Calibration methods to fit parameters within complex biological models 2023 ·Frontiers in Applied Mathematics and Statistics ·Pariksheet Nanda, Denise E. Kirschner	5
3	To Sobol or not to Sobol? The effects of sampling schemes in systems biology applications 2021 ·Mathematical Biosciences ·Marissa Renardy, Louis R. Joslyn, Jess A. Millar, Denise E. Kirschner	69
4	Multi-scale models of lung fibrosis 2020 ·Matrix Biology ·(unknown), Stephanie Evans, Riley T. Hannan, Thomas H. Barker, Jason H. T. Bates, Catherine A. Bonham, Bethany B. Moore, Denise E. Kirschner, Shayn M. Peirce	21
5	A computational model tracks whole-lung Mycobacterium tuberculosis infection and predicts factors that inhibit dissemination 2020 ·PLoS Computational Biology ·Timothy Wessler, Louis R. Joslyn, H. Jacob Borish, Hannah P. Gideon, JoAnne L. Flynn, Denise E. Kirschner, Jennifer J. Linderman	20
6	IL-10 Impairs Local Immune Response in Lung Granulomas and Lymph Nodes during Early Mycobacterium tuberculosis Infection 2019 ·The Journal of Immunology ·Eileen A. Wong, Stephanie Evans, (unknown), (unknown), Pauline Maiello, (unknown), Anthony M. Cadena, Edwin Klein, (unknown), Alexander G. White, (unknown), (unknown), Jaime Tomko, Joshua T. Mattila, Hannah P. Gideon, Philana Ling Lin, Keith A. Reimann, Denise E. Kirschner, JoAnne L. Flynn	46
7	Deletion of TGF-β1 Increases Bacterial Clearance by Cytotoxic T Cells in a Tuberculosis Granuloma Model 2017 ·Frontiers in Immunology ·Hayley Warsinske, Elsje Pienaar, Jennifer J. Linderman, Joshua T. Mattila, Denise E. Kirschner	48
8	Systems biology approaches for understanding cellular mechanisms of immunity in lymph nodes during infection 2011 ·Journal of Theoretical Biology ·Henry Mirsky, Mark J. Miller, Jennifer J. Linderman, Denise E. Kirschner	33
9	Characterizing the Dynamics of CD4+ T Cell Priming within a Lymph Node 2010 ·The Journal of Immunology ·Jennifer J. Linderman, Thomas W. Riggs, Manjusha Pande, Mark J. Miller, Simeone Marino, Denise E. Kirschner	48
10	TNF and IL-10 are major factors in modulation of the phagocytic cell environment in lung and lymph node in tuberculosis: A next-generation two-compartmental model 2010 ·Journal of Theoretical Biology ·Simeone Marino, Amy Myers, JoAnne L. Flynn, Denise E. Kirschner	71
11	Synergy between Individual TNF-Dependent Functions Determines Granuloma Performance for Controlling Mycobacterium tuberculosis Infection 2009 ·The Journal of Immunology ·J. Christian J. Ray, JoAnne L. Flynn, Denise E. Kirschner	123
12	Chemokine and Cytokine Mediated Loss of Regulatory T Cells in Lymph Nodes during Pathogenic Simian Immunodeficiency Virus Infection 2008 ·The Journal of Immunology ·Shulin Qin, Yongjun Sui, Adam C. Soloff, Beth A. Fallert Junecko, Denise E. Kirschner, Michael Murphey‐Corb, Simon C. Watkins, Patrick M. Tarwater, James E. Pease, Simon M. Barratt‐Boyes, Todd A. Reinhart	36
13	Virologic and Immunologic Events in Hilar Lymph Nodes During Simian Immunodeﬁciency Virus Infection - Development of Polarized Inﬂammation 2008 ·Deep Blue (University of Michigan) ·Beth A. Fallert, (unknown), Todd M. Schaefer, Melanie E. Pfeifer, Sonali Sanghavi, Simon C. Watkins, Michael Murphey‐Corb, Patrick M. Tarwater, Denise E. Kirschner, Todd A. Reinhart	1
14	Contribution of CD8+ T cells to control of Mycobacterium tuberculosis infection. 2006 ·The Journal of Immunology ·(unknown), (unknown), (unknown), Denise E. Kirschner	1
15	Multiple mechanisms allow Mycobacterium tuberculosis to continuously inhibit MHC class II-mediated antigen presentation by macrophages 2005 ·Proceedings of the National Academy of Sciences ·Stewart T. Chang, Jennifer J. Linderman, Denise E. Kirschner	66
16	Dendritic Cell Trafficking and Antigen Presentation in the Human Immune Response to Mycobacterium tuberculosis 2004 ·The Journal of Immunology ·Simeone Marino, Santosh Pawar, Craig L. Fuller, Todd A. Reinhart, JoAnne L. Flynn, Denise E. Kirschner	100
17	The Effects of Different HIV Type 1 Strains on Human Thymic Function 2002 ·AIDS Research and Human Retroviruses ·Ping Ye, Athena P. Kourtis, Denise E. Kirschner	10
18	Reevaluation of T Cell Receptor Excision Circles as a Measure of Human Recent Thymic Emigrants 2002 ·The Journal of Immunology ·Ping Ye, Denise E. Kirschner	97
19	A Model to Predict Cell-Mediated Immune Regulatory Mechanisms During Human Infection with Mycobacterium tuberculosis 2001 ·The Journal of Immunology ·Janis Wigginton, Denise E. Kirschner	185
20	Revisiting Early Models of the host-pathogen interactions in HIV infection 2000 ·Deep Blue (University of Michigan) ·David S. Covert, Denise E. Kirschner	13

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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