Ewart de Bruijn

7.8k citations

35 papers · 4.3k indexed · 2 hit papers · h-index 24

Co-authors: Wigard P. Kloosterman Ronald H.A. Plasterk Erno Wienholds Sakari Kauppinen Edwin Cuppen Eugène Berezikov H. Robert Horvitz Ezequiel Alvarez-Saavedra
Topics: Cancer Genomics and Diagnostics (11 papers)Genetic factors in colorectal cancer (7 papers)CRISPR and Genetic Engineering (7 papers)
Cited by: Cancer Research Molecular Biology Aging
Journals: Nature Science Nucleic Acids Research
Partner nations: Netherlands United Kingdom United States

In The Last Decade

Ewart de Bruijn

33 papers receiving 4.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

MicroRNA Expression in Zebrafish Embryonic Development

2005 1.3k citations Erno Wienholds, Wigard P. Kloosterman et al. Science profile →
A systematic genome-wide analysis of zebrafish protein-coding gene function

2013 445 citations Ross Kettleborough, Elisabeth M. Busch‐Nentwich et al. Nature profile →

Peers

Countries citing papers authored by Ewart de Bruijn

Since Specialization

Citations

This map shows the geographic impact of Ewart de Bruijn's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ewart de Bruijn with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ewart de Bruijn more than expected).

Fields of papers citing papers by Ewart de Bruijn

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ewart de Bruijn. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ewart de Bruijn. The network helps show where Ewart de Bruijn may publish in the future.

Co-authorship network of co-authors of Ewart de Bruijn

This figure shows the co-authorship network connecting the top 25 collaborators of Ewart de Bruijn. A scholar is included among the top collaborators of Ewart de Bruijn based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ewart de Bruijn. Ewart de Bruijn is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A multi-platform reference for somatic structural variation detection 2022 ·Cell Genomics ·Jose Espejo Valle-Inclán,Nicolle Besselink,Ewart de Bruijn,Daniel Cameron,Jana Ebler,Joachim Kutzera,Stef van Lieshout,Tobias Marschall,Marcel Nelen,Peter Priestley,Ivo Renkens,Margaretha G.M. Roemer,Markus J. van Roosmalen,Aaron M. Wenger,Bauke Ylstra,Remond J.A. Fijneman,Wigard P. Kloosterman,Edwin Cuppen	17
2	Clinical Validation of Whole Genome Sequencing for Cancer Diagnostics 2021 ·Journal of Molecular Diagnostics ·Paul Roepman,Ewart de Bruijn,Stef van Lieshout,(unknown),Mirjam C. Boelens,Hendrikus J. Dubbink,Willemina R.R. Geurts-Giele,Floris H. Groenendijk,Manon M. H. Huibers,Mariëtte E.G. Kranendonk,Margaretha G.M. Roemer,Kris G. Samsom,Marloes Steehouwer,Wendy W.J. de Leng,Alexander Hoischen,Bauke Ylstra,Kim Monkhorst,Jacobus J. M. van der Hoeven,Edwin Cuppen	39
3	Micro-costing diagnostics in oncology: from single-gene testing to whole- genome sequencing 2021 ·Expert Review of Pharmacoeconomics & Outcomes Research ·(unknown),Bastiaan B.J. Tops,Elisabeth M. P. Steeghs,Veerle M.H. Coupé,Katrien Grünberg,Eiko K. de Jong,Ed Schuuring,Stefan M. Willems,Marjolijn J. L. Ligtenberg,Valesca P. Retèl,(unknown),Ewart de Bruijn,Edwin Cuppen,Geert Frederix	23
4	Analytical demands to use whole-genome sequencing in precision oncology 2021 ·Seminars in Cancer Biology ·Manja Meggendorfer,Vaidehi Jobanputra,Kazimierz O. Wrzeszczyński,Paul Roepman,Ewart de Bruijn,Edwin Cuppen,Reinhard Büttner,Carlos Caldas,Sean M. Grimmond,Charles G. Mullighan,Olivier Elemento,Richard Rosenquist,Anna Schuh,Torsten Haferlach	27
5	1189O Validation of whole genome sequencing in routine clinical practice 2020 ·Annals of Oncology ·Kim Monkhorst,Kris G. Samsom,Luuk J. Schipper,Paul Roepman,Linda J.W. Bosch,Ewart de Bruijn,Louisa R. Hoes,(unknown),(unknown),Lizet van der Kolk,Tineke E. Buffart,(unknown),Emile E. Voest,Edwin Cuppen,Gerrit A. Meijer	5
6	Mapping and phasing of structural variation in patient genomes using nanopore sequencing 2017 ·Nature Communications ·(unknown),Markus J. van Roosmalen,Ivo Renkens,Marleen M. Nieboer,Sjors Middelkamp,Joep de Ligt,Giulia Pregno,Daniela Giachino,Giorgia Mandrile,Jose Espejo Valle-Inclán,Jerome Korzelius,Ewart de Bruijn,Edwin Cuppen,Michael E. Talkowski,Tobias Marschall,Jeroen de Ridder,Wigard P. Kloosterman	249
7	Large-Scale Identification of Coregulated Enhancer Networks in the Adult Human Brain 2014 ·Cell Reports ·Marit W. Vermunt,Peter Reinink,Jeroen Korving,Ewart de Bruijn,(unknown),Onur Başak,Geert Geeven,Pim W. Toonen,Nico Lansu,Charles Meunier,Sebastiaan van Heesch,Hans Clevers,Wouter de Laat,Edwin Cuppen,Menno P. Creyghton	59
8	A systematic genome-wide analysis of zebrafish protein-coding gene functionbreakdown → 2013 ·Nature ·Ross Kettleborough,Elisabeth M. Busch‐Nentwich,Steven Harvey,Christopher M. Dooley,Ewart de Bruijn,Fredericus J. M. van Eeden,Ian M. Sealy,Richard White,Colin Herd,Isaäc J. Nijman,(unknown),(unknown),Catherine M. Scahill,Richard J. Gibbons,Neha Wali,Samantha Carruthers,Amanda Hall,Jennifer Yen,Edwin Cuppen,Derek L. Stemple	445
9	Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel 2012 ·Genome biology ·Marieke Simonis,Santosh S. Atanur,Sam Linsen,Victor Guryev,(unknown),Laurence Gamé,Nico Lansu,Ewart de Bruijn,Sebastiaan van Heesch,Steven J.M. Jones,Michal Pravenec,Timothy J. Aitman,Edwin Cuppen	22
10	Primary Colorectal Cancers and Their Subsequent Hepatic Metastases Are Genetically Different: Implications for Selection of Patients for Targeted Treatment 2011 ·Clinical Cancer Research ·Joost S.P. Vermaat,Isaäc J. Nijman,Marco J. Koudijs,(unknown),Stefan Scherer,Michal Mokrý,Wijnand Roessingh,Nico Lansu,Ewart de Bruijn,Richard van Hillegersberg,P. J. van Diest,Edwin Cuppen,Emile E. Voest	119
11	High-Throughput Target-Selected Gene Inactivation in Zebrafish 2011 ·Methods in cell biology ·Ross Kettleborough,Ewart de Bruijn,Fredericus J. M. van Eeden,Edwin Cuppen,Derek L. Stemple	36
12	Single Nucleotide Polymorphism (SNP) Panels for Rapid Positional Cloning in Zebrafish 2011 ·Methods in cell biology ·Matthew D. Clark,Victor Guryev,Ewart de Bruijn,Isaäc J. Nijman,Masazumi Tada,Catherine Wilson,Panos Deloukas,John H. Postlethwait,Edwin Cuppen,Derek L. Stemple	6
13	Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germline† 2011 ·Human Molecular Genetics ·Wigard P. Kloosterman,Victor Guryev,(unknown),Karen Duran,Ewart de Bruijn,(unknown),Tom G.W. Letteboer,(unknown),Ron Hochstenbach,Martin Poot,Edwin Cuppen	225
14	Efficient Double Fragmentation ChIP-seq Provides Nucleotide Resolution Protein-DNA Binding Profiles 2010 ·PLoS ONE ·Michal Mokrý,Pantelis Hatzis,Ewart de Bruijn,Jan Köster,Rogier Versteeg,Jurian Schuijers,Marc van de Wetering,Victor Guryev,Hans Clevers,Edwin Cuppen	34
15	Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples 2010 ·Nature Methods ·Isaäc J. Nijman,Michal Mokrý,Ruben van Boxtel,Pim W. Toonen,Ewart de Bruijn,Edwin Cuppen	55
16	Mismatch repair deficiency does not enhance ENU mutagenesis in the zebrafish germ line 2008 ·Mutagenesis ·Harma Feitsma,Ewart de Bruijn,José van de Belt,Isaäc J. Nijman,Edwin Cuppen	8
17	MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system 2007 ·Genome biology ·Marika Kapsimali,Wigard P. Kloosterman,Ewart de Bruijn,Frédéric Rosa,Ronald H.A. Plasterk,Stephen W. Wilson	326
18	Cloning and expression of new microRNAs from zebrafish 2006 ·Nucleic Acids Research ·Wigard P. Kloosterman,Florian Steiner,Eugène Berezikov,Ewart de Bruijn,José van de Belt,Mark Verheul,Edwin Cuppen,Ronald H.A. Plasterk	146
19	MicroRNA Expression in Zebrafish Embryonic Developmentbreakdown → 2005 ·Science ·Erno Wienholds,Wigard P. Kloosterman,Eric A. Miska,Ezequiel Alvarez-Saavedra,Eugène Berezikov,Ewart de Bruijn,H. Robert Horvitz,Sakari Kauppinen,Ronald H.A. Plasterk	1284
20	Effective use of a neutrophic ACTH_4–9 analogue in the treatment of a peripheral demyelinating syndrome (experimental allergic neuritis) 1994 ·Brain ·Henricus J. Duckers,Joost Verhaagen,Ewart de Bruijn,W.H. Gispen	15

About Ewart de Bruijn

Ewart de Bruijn is a scholar working on Cancer Research, Pathology and Forensic Medicine and Molecular Biology, having authored 35 papers that have together received 4.3k indexed citations. Recurring topics across this work include Cancer Genomics and Diagnostics (11 papers), Genetic factors in colorectal cancer (7 papers) and CRISPR and Genetic Engineering (7 papers). The work is most often cited by research in Cancer Research (2.4k citations), Molecular Biology (3.2k citations) and Aging (49 citations). Ewart de Bruijn has collaborated with scholars based in Netherlands, United Kingdom and United States. Frequent co-authors include Wigard P. Kloosterman, Ronald H.A. Plasterk, Erno Wienholds, Sakari Kauppinen, Edwin Cuppen, Eugène Berezikov, H. Robert Horvitz, Ezequiel Alvarez-Saavedra, Eric A. Miska and Isaäc J. Nijman. Their work appears in journals such as Nature, Science and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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