Duncan Sproul

5.0k citations

35 papers · 2.9k indexed · h-index 21

Impact in

Molecular Biology top 2%
- Epigenetics and DNA Methylation
- Genomics and Chromatin Dynamics
- RNA modifications and cancer
- RNA Research and Splicing
- Cancer-related gene regulation
- Nuclear Structure and Function
- RNA and protein synthesis mechanisms
Aging top 5%

Papers in

Aging 1
Molecular Biology 32
- Epigenetics and DNA Methylation 23
- Genomics and Chromatin Dynamics 11
- RNA modifications and cancer 8
- Cancer-related gene regulation 8
- RNA Research and Splicing 3
- CRISPR and Genetic Engineering 3

Co-authors: Wendy A. Bickmore Nick Gilbert Richard R. Meehan David J. Harrison Shelagh Boyle J. Michael Dixon Colm E. Nestor Bernard Ramsahoye
Journals: Genome biology (4 papers)Nature Communications (3 papers)Nucleic Acids Research (3 papers)Proceedings of the National Academy of Sciences (2 papers)PLoS Genetics (2 papers)
Partner nations: United Kingdom United States Netherlands

In The Last Decade

Duncan Sproul

32 papers receiving 2.9k citations

Peers

Countries citing papers authored by Duncan Sproul

Since Specialization

Citations

This map shows the geographic impact of Duncan Sproul's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Duncan Sproul with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Duncan Sproul more than expected).

Fields of papers citing papers by Duncan Sproul

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Duncan Sproul. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Duncan Sproul. The network helps show where Duncan Sproul may publish in the future.

Co-authors

The 25 scholars most cited alongside Duncan Sproul, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Duncan Sproul Line = papers co-authored together Duncan Sproul links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Discovery and Characterization of Uracil Derivatives Targeting the Set-and-Ring Domain of UHRF1 Journal of Chemical Information and Modeling ·Ifigeneia Akrani, Danai Driva, Efstratios Tsakalidis, Nandini Mozumdar, Danai Mavridi, Anthi Panara, Kalypso Epiphaniou, Maria Chalkiadaki, A.F. Wright, Maria Halabalaki, Angeliki Tsoka, Grigoris Zoidis, Constantinos E. Vorgias, Duncan Sproul, Evagelos Gikas, Skirmantas Kriaučionis, Emmanuel Mikros, Vassilios Myrianthopoulos	2025	0
2	Using human disease mutations to understand de novo DNA methyltransferase function Biochemical Society Transactions ·Willow Rolls, Marcus D. Wilson, Duncan Sproul	2024	1
3	DNMT3B PWWP mutations cause hypermethylation of heterochromatin EMBO Reports ·Francesca Taglini, Ioannis Kafetzopoulos, Willow Rolls, Kamila Irena Musialik, Heng Yang Lee, Yujie Zhang, Mattia Marenda, Lyndsay Kerr, Hannah Finan, Cristina Rubio-Ramon, Philippe Gautier, Hannah Wapenaar, Dhananjay Kumar, Hazel Davidson‐Smith, Jimi Wills, Laura C. Murphy, Ann Wheeler, Marcus D. Wilson, Duncan Sproul	2024	6
4	The N-terminal region of DNMT3A engages the nucleosome surface to aid chromatin recruitment EMBO Reports ·Hannah Wapenaar, Gillian Clifford, Willow Rolls, Maud Pasquier, Hayden Burdett, Yujie Zhang, Gauri Deák, Juan Zou, Christos Spanos, Mark R D Taylor, J Mills, James A. Watson, Dhananjay Kumar, Richard Clark, Alakta Das, Devisree Valsakumar, Janice Bramham, Philipp Voigt, Duncan Sproul, Marcus D. Wilson	2024	5
5	Germline de novo mutations in families with Mendelian cancer syndromes caused by defects in DNA repair Nature Communications ·Kitty Sherwood, Joseph C. Ward, Ignacio Soriano, Lynn Martin, Archie Campbell, Raheleh Rahbari, Ioannis Kafetzopoulos, Duncan Sproul, Andrew Green, Julian R. Sampson, Alan Donaldson, Kai‐Ren Ong, Karl Heinimann, Maartje Nielsen, Huw Thomas, Andrew Latchford, Claire Palles, Ian Tomlinson	2023	7
6	In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma Cancer Research ·Nicholas T. Younger, Mollie L. Wilson, Anabel Martinez Lyons, Edward J. Jarman, Alison Meynert, Graeme R. Grimes, Konstantinos Gournopanos, Scott H. Waddell, Peter A. Tennant, David H. Wilson, Rachel V. Guest, Stephen J. Wigmore, Juan Carlos Acosta, Timothy J. Kendall, Martin S. Taylor, Duncan Sproul, Pleasantine Mill, Luke Boulter	2022	7
7	De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands Nature Communications ·Roza Masalmeh, Francesca Taglini, Cristina Rubio-Ramon, Kamila Irena Musialik, Jonathan Higham, Hazel Davidson‐Smith, Ioannis Kafetzopoulos, Kamila Pawlicka, Hannah Finan, Richard Clark, Jimi Wills, Andrew J. Finch, Lee Murphy, Duncan Sproul	2021	31
8	Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions Genome biology ·John Cole, Neil Robertson, Mohammed Rather, John P. Thomson, Tony McBryan, Duncan Sproul, Tina Wang, Claire Brock, William Clark, Trey Ideker, Richard R. Meehan, Richard A. Miller, Holly M. Brown‐Borg, Peter D. Adams	2017	130
9	Estrogen-induced chromatin decondensation and nuclear re-organization linked to regional epigenetic regulation in breast cancer Genome biology ·Sehrish Rafique, Jeremy Thomas, Duncan Sproul, Wendy A. Bickmore	2015	34
10	FOXA1 repression is associated with loss of BRCA1 and increased promoter methylation and chromatin silencing in breast cancer Oncogene ·Chun Gong, Kazunari Fujino, Lara J. Monteiro, Ana Gomes, Rinske Drost, Hazel Davidson‐Smith, Satoru Takeda, US Khoo, Jos Jonkers, Duncan Sproul, Eric W.‐F. Lam	2014	32
11	Genomic insights into cancer-associated aberrant CpG island hypermethylation Briefings in Functional Genomics ·Duncan Sproul, Richard R. Meehan	2013	91
12	Expression of a large LINE-1-driven antisense RNA is linked to epigenetic silencing of the metastasis suppressor gene TFPI-2 in cancer Nucleic Acids Research ·Hazel A. Cruickshanks, Natasha Vafadar-Isfahani, Donncha S. Dunican, Andy Lee, Duncan Sproul, Jonathan N. Lund, Richard R. Meehan, Cristina Tufarelli	2013	48
13	DNA methylation reprogramming in cancer: Does it act by re‐configuring the binding landscape of Polycomb repressive complexes? BioEssays ·James P. Reddington, Duncan Sproul, Richard R. Meehan	2013	28
14	Diversity of Matriptase Expression Level and Function in Breast Cancer PLoS ONE ·Arkadiusz Welman, Duncan Sproul, Peter Mullen, Morwenna Muir, Andrew Kinnaird, David J. Harrison, Dana Faratian, Valerie G. Brunton, Margaret C. Frame	2012	21
15	Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes Genome Research ·Colm E. Nestor, Raffaele Ottaviano, James P. Reddington, Duncan Sproul, Diana Reinhardt, Donncha S. Dunican, Elad Katz, J. Michael Dixon, David J. Harrison, Richard R. Meehan	2011	326
16	Modelling genetic and clinical heterogeneity in epithelial ovarian cancers Carcinogenesis ·Kate Lawrenson, Duncan Sproul, Barbara Grün, Maria Notaridou, Elizabeth Benjamin, Ian Jacobs, Dimitra Dafou, Andrew H. Sims, Simon A. Gayther	2011	27
17	Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination Molecular Cell ·Ragnhild Eskeland, Martin Leeb, Graeme R. Grimes, Clémence Kress, Shelagh Boyle, Duncan Sproul, Nick Gilbert, Yuhong Fan, Arthur I. Skoultchi, Anton Wutz, Wendy A. Bickmore	2010	418
18	Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells PLoS Genetics ·Lee Finlan, Duncan Sproul, Inga Thomson, Shelagh Boyle, Elizabeth Kerr, Paul Perry, Bauke Ylstra, Jonathan R. Chubb, Wendy A. Bickmore	2008	448
19	The role of chromatin structure in regulating the expression of clustered genes Nature Reviews Genetics ·Duncan Sproul, Nick Gilbert, Wendy A. Bickmore	2005	230
20	Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes. Genome Biology ·Liam P. Keegan, Anne Leroy, Duncan Sproul, Mary A. O’Connell	2004	123

About Duncan Sproul

Duncan Sproul is a scholar working on Aging, Molecular Biology, Cancer Research, Immunology and Allergy and Genetics, having authored 35 papers that have together received 2.9k indexed citations. Recurring topics across this work include Epigenetics and DNA Methylation (23 papers), Genomics and Chromatin Dynamics (11 papers), RNA modifications and cancer (8 papers), Cancer-related gene regulation (8 papers), Genetic Syndromes and Imprinting (4 papers), RNA Research and Splicing (3 papers), CRISPR and Genetic Engineering (3 papers) and Genetics and Neurodevelopmental Disorders (3 papers). The work is most often cited by research in Molecular Biology (2.5k citations), Aging (53 citations), Cancer Research (382 citations), Genetics (450 citations) and Immunology (165 citations). Duncan Sproul has collaborated with scholars based in United Kingdom, United States and Netherlands. Frequent co-authors include Wendy A. Bickmore, Nick Gilbert, Richard R. Meehan, David J. Harrison, Shelagh Boyle, J. Michael Dixon, Colm E. Nestor, Bernard Ramsahoye, Jonathan R. Chubb and Bauke Ylstra. Their work appears in journals such as Genome biology, Nature Communications, Nucleic Acids Research, Proceedings of the National Academy of Sciences and PLoS Genetics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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