Donald S. Backos

6.2k citations

68 papers · 4.2k indexed · 1 hit paper · h-index 30

Impact in

Geriatrics and Gerontology top 1%
- Sirtuins and Resveratrol in Medicine
Cellular and Molecular Neuroscience top 2%
- Neuroscience and Neuropharmacology Research

Papers in

Geriatrics and Gerontology 5
- Sirtuins and Resveratrol in Medicine 5
Toxicology 3

Co-authors: Philip Reigan Christopher J. Matheson José A. Esteban Christopher C. Franklin Steffanie L. Furtek Nashaat Z. Gerges Tyler C. Brown Terrance J. Kavanagh
Journals: Journal of Biological Chemistry (6 papers)Bioorganic & Medicinal Chemistry (6 papers)Molecular Pharmacology (4 papers)Free Radical Biology and Medicine (4 papers)Cell Metabolism (2 papers)
Partner nations: United States United Kingdom China

In The Last Decade

Donald S. Backos

66 papers receiving 4.2k citations

Hit Papers

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Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo 2016 · 455 citations

Peers

Countries citing papers authored by Donald S. Backos

Since Specialization

Citations

This map shows the geographic impact of Donald S. Backos's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Donald S. Backos with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Donald S. Backos more than expected).

Fields of papers citing papers by Donald S. Backos

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Donald S. Backos. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Donald S. Backos. The network helps show where Donald S. Backos may publish in the future.

Co-authors

The 25 scholars most cited alongside Donald S. Backos, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Donald S. Backos Line = papers co-authored together Donald S. Backos links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Endocrine-Disrupting Activities of Flavones on Steroid Receptors: Structural Requirements and Synthesis of Novel Flavone with Improved Estrogenic Activity Biomedicines ·Steven K. Nordeen, Vijay Kumar, B J Bona, Joshua Batson, Donald S. Backos, Michael F. Wempe	2025	1
2	Statin therapy inhibits fatty acid synthase via dynamic protein modifications Nature Communications ·Alec Trub, Gregory R. Wagner, Kristin A. Anderson, Scott B. Crown, Guofang Zhang, J. Will Thompson, Olga Ilkayeva, Robert D. Stevens, Paul A. Grimsrud, Rhushikesh A. Kulkarni, Donald S. Backos, Jordan L. Meier, Matthew D. Hirschey	2022	18
3	Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice Journal of Biological Chemistry ·Dhaval P. Bhatt, Christine A. Mills, Kristin A. Anderson, Bárbara J. Henriques, Tânia G. Lucas, Sara Francisco, Juan Liu, Olga Ilkayeva, Alexander E. Adams, Shreyas Kulkarni, Donald S. Backos, Michael B. Major, Paul A. Grimsrud, Cláudio M. Gomes, Matthew D. Hirschey	2022	13
4	Characterization of a Primordial Major Capsid-Scaffolding Protein Complex in Icosahedral Virus Shell Assembly Journal of Molecular Biology ·Christal R. Davis, Donald S. Backos, Marc C. Morais, Mair E. A. Churchill, Carlos E. Catalano	2022	4
5	N-Substituted pyrrolopyrimidines and purines as p90 ribosomal S6 protein kinase-2 (RSK2) inhibitors Bioorganic & Medicinal Chemistry ·Kimberly A. Casalvieri, Christopher J. Matheson, Becka M. Warfield, Donald S. Backos, Philip Reigan	2021	8
6	Computational Modeling of NLRP3 Identifies Enhanced ATP Binding and Multimerization in Cryopyrin-Associated Periodic Syndromes Frontiers in Immunology ·Jenny Mae Samson, Dinoop Ravindran Menon, Prasanna K. Vaddi, Nazanin Kalani Williams, Joanne Domenico, Zili Zhai, Donald S. Backos, Mayumi Fujita	2020	9
7	Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors European Journal of Medicinal Chemistry ·Christopher J. Matheson, Kimberly A. Casalvieri, Donald S. Backos, Mohammed Minhajuddin, Craig T. Jordan, Philip Reigan	2020	20
8	Molecular docking of substituted pteridinones and pyrimidines to the ATP-binding site of the N-terminal domain of RSK2 and associated MM/GBSA and molecular field datasets SHILAP Revista de lepidopterología ·Kimberly A. Casalvieri, Christopher J. Matheson, Donald S. Backos, Philip Reigan	2020	23
9	Isoxazolo[3,4-d]pyridazinones positively modulate the metabotropic glutamate subtypes 2 and 4 Bioorganic & Medicinal Chemistry ·Christina Gates, Donald S. Backos, Philip Reigan, Hye Jin Kang, Chris Koerner, Joseph Mirzaei, Nicholas R. Natale	2018	1
10	Compensatory Expression of Nur77 and Nurr1 Regulates NF-κB–Dependent Inflammatory Signaling in Astrocytes Molecular Pharmacology ·Katriana A. Popichak, Sean L. Hammond, Julie A. Moreno, Maryam F. Afzali, Donald S. Backos, Richard D. Slayden, Stephen Safe, Ronald B. Tjalkens	2018	45
11	Chronic Ethanol Metabolism Inhibits Hepatic Mitochondrial Superoxide Dismutase via Lysine Acetylation Alcoholism Clinical and Experimental Research ·Mohammed A. Assiri, Samantha R. Roy, Peter S. Harris, Hadi Ali, Yongliang Liang, Colin T. Shearn, David J. Orlicky, James R. Roede, Matthew D. Hirschey, Donald S. Backos, Kristofer S. Fritz	2017	25
12	SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion Cell Metabolism ·Kristin A. Anderson, Frank K. Huynh, Kelsey H. Fisher‐Wellman, J. Darren Stuart, Brett S. Peterson, Jonathan D. Douros, Gregory R. Wagner, J. Will Thompson, Andreas S. Madsen, Michelle Green, R. Michael Sivley, Olga Ilkayeva, Robert D. Stevens, Donald S. Backos, John A. Capra, Christian A. Olsen, Jonathan E. Campbell, Deborah M. Muoio, Paul A. Grimsrud, Matthew D. Hirschey	2017	256
13	Dimeric isoxazolyl-1,4-dihydropyridines have enhanced binding at the multi-drug resistance transporter Bioorganic & Medicinal Chemistry ·Scott A. Steiger, Chun Li, Donald S. Backos, Philip Reigan, Nicholas R. Natale	2017	14
14	Targeting WEE1 Kinase in Cancer Trends in Pharmacological Sciences ·Christopher J. Matheson, Donald S. Backos, Philip Reigan	2016	306
15	Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH Journal of Biological Chemistry ·Andreas S. Madsen, Christian Dybdahl Andersen, Mohammad Daoud, Kristin A. Anderson, Jonas S. Laursen, Saswati Chakladar, Frank K. Huynh, Ana R. Colaço, Donald S. Backos, Peter Fristrup, Matthew D. Hirschey, Christian A. Olsen	2016	83
16	Oxidative stress-mediated aldehyde adduction of GRP78 in a mouse model of alcoholic liver disease: functional independence of ATPase activity and chaperone function Free Radical Biology and Medicine ·James J. Galligan, Kristofer S. Fritz, Donald S. Backos, Colin T. Shearn, Rebecca L. Smathers, Hua Jiang, Kenneth N. Maclean, Philip Reigan, Dennis R. Petersen	2014	41
17	Increased carbonylation of the lipid phosphatase PTEN contributes to Akt2 activation in a murine model of early alcohol-induced steatosis Free Radical Biology and Medicine ·Colin T. Shearn, Rebecca L. Smathers, Donald S. Backos, Philip Reigan, David J. Orlicky, Dennis R. Petersen	2013	63
18	Identification of Functionally Relevant Lysine Residues That Modulate Human Farnesoid X Receptor Activation Molecular Pharmacology ·An–Qiang Sun, Yuhuan Luo, Donald S. Backos, Shuhua Xu, Natarajan Balasubramaniyan, Philip Reigan, Frederick J. Suchy	2013	7
19	Post-Translational Oxidative Modification and Inactivation of Mitochondrial Complex I in Epileptogenesis Journal of Neuroscience ·Kristen Ryan, Donald S. Backos, Philip Reigan, Manisha Patel	2012	76
20	Manipulation of cellular GSH biosynthetic capacity via TAT-mediated protein transduction of wild-type or a dominant-negative mutant of glutamate cysteine ligase alters cell sensitivity to oxidant-induced cytotoxicity Toxicology and Applied Pharmacology ·Donald S. Backos, Chad Brocker, Christopher C. Franklin	2009	6

About Donald S. Backos

Donald S. Backos is a scholar working on Geriatrics and Gerontology, Toxicology, Biochemistry, Molecular Biology and Physiology, having authored 68 papers that have together received 4.2k indexed citations. Recurring topics across this work include Neuroscience and Neuropharmacology Research (8 papers), Sirtuins and Resveratrol in Medicine (5 papers), Computational Drug Discovery Methods (5 papers), Adipose Tissue and Metabolism (5 papers), Melanoma and MAPK Pathways (4 papers), Endoplasmic Reticulum Stress and Disease (4 papers), CRISPR and Genetic Engineering (4 papers) and DNA and Nucleic Acid Chemistry (4 papers). The work is most often cited by research in Geriatrics and Gerontology (326 citations), Cellular and Molecular Neuroscience (794 citations), Molecular Biology (2.3k citations), Cell Biology (475 citations) and Biochemistry (204 citations). Donald S. Backos has collaborated with scholars based in United States, United Kingdom and China. Frequent co-authors include Philip Reigan, Christopher J. Matheson, José A. Esteban, Christopher C. Franklin, Steffanie L. Furtek, Nashaat Z. Gerges, Tyler C. Brown, Terrance J. Kavanagh, Collin C. White and Isaac Mohar. Their work appears in journals such as Journal of Biological Chemistry, Bioorganic & Medicinal Chemistry, Molecular Pharmacology, Free Radical Biology and Medicine and Cell Metabolism.

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