Derek S. Tan

5.6k total citations · 1 hit paper
85 papers, 4.0k citations indexed

About

Derek S. Tan is a scholar working on Molecular Biology, Organic Chemistry and Pharmacology. According to data from OpenAlex, Derek S. Tan has authored 85 papers receiving a total of 4.0k indexed citations (citations by other indexed papers that have themselves been cited), including 49 papers in Molecular Biology, 45 papers in Organic Chemistry and 17 papers in Pharmacology. Recurrent topics in Derek S. Tan's work include Chemical Synthesis and Analysis (19 papers), Synthetic Organic Chemistry Methods (17 papers) and Microbial Natural Products and Biosynthesis (16 papers). Derek S. Tan is often cited by papers focused on Chemical Synthesis and Analysis (19 papers), Synthetic Organic Chemistry Methods (17 papers) and Microbial Natural Products and Biosynthesis (16 papers). Derek S. Tan collaborates with scholars based in United States, Germany and Nepal. Derek S. Tan's co-authors include Renato A. Bauer, Christopher F. Stratton, Jacqueline Wurst, Xuequan Lu, David Y. Gin, Luis E. N. Quadri, Julián A. Ferreras, Todd A. Wenderski, Stuart L. Schreiber and Shiying Shang and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Derek S. Tan

83 papers receiving 4.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Diversity-oriented synthesis: exploring the intersections between chemistry and biology

2005 517 citations Derek S. Tan Nature Chemical Biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Derek S. Tan United States	37	2.2k	2.1k	695	311	266	85	4.0k
Sankaranarayanan Murugesan India	32	1.1k 0.5×	1.7k 0.8×	332 0.5×	334 1.1×	449 1.7×	204	3.4k
Jiyong Hong United States	33	1.8k 0.8×	1.4k 0.7×	467 0.7×	515 1.7×	96 0.4×	95	3.4k
Diogo Santos‐Martins United States	16	2.7k 1.2×	1.0k 0.5×	474 0.7×	421 1.4×	1.1k 4.2×	30	5.0k
Warren R. J. D. Galloway United Kingdom	26	1.9k 0.9×	2.0k 1.0×	350 0.5×	157 0.5×	219 0.8×	68	3.6k
Kenneth F. Bastow United States	49	3.5k 1.6×	3.4k 1.7×	1.2k 1.7×	575 1.8×	94 0.4×	188	7.5k
Courtney C. Aldrich United States	42	3.1k 1.4×	1.5k 0.7×	1.5k 2.1×	271 0.9×	186 0.7×	164	5.0k
Jérôme Eberhardt United States	11	2.0k 0.9×	740 0.4×	371 0.5×	315 1.0×	856 3.2×	19	3.9k
Zhenyuan Miao China	34	1.9k 0.9×	2.6k 1.3×	475 0.7×	505 1.6×	236 0.9×	109	4.4k
Xiayang Qiu United States	34	2.4k 1.1×	804 0.4×	396 0.6×	624 2.0×	266 1.0×	61	4.9k
Deborah L. Zink United States	40	2.3k 1.0×	1.8k 0.9×	2.3k 3.3×	202 0.6×	117 0.4×	138	4.9k

Countries citing papers authored by Derek S. Tan

Since Specialization

Citations

This map shows the geographic impact of Derek S. Tan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Derek S. Tan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Derek S. Tan more than expected).

Fields of papers citing papers by Derek S. Tan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Derek S. Tan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Derek S. Tan. The network helps show where Derek S. Tan may publish in the future.

Co-authorship network of co-authors of Derek S. Tan

This figure shows the co-authorship network connecting the top 25 collaborators of Derek S. Tan. A scholar is included among the top collaborators of Derek S. Tan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Derek S. Tan. Derek S. Tan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Buglino, John A., et al.. (2025). Chalkophore-mediated respiratory oxidase flexibility controls M. tuberculosis virulence. eLife. 14. 1 indexed citations

Du, Tim, Derek S. Tan, George G. Zhanel, et al.. (2025). Surveillance of Clostridioides difficile in Canadian retail meat and genomic linkages to community-associated human clinical infections in Canada. Canadian Journal of Microbiology. 71. 1–7.

Buglino, John A., et al.. (2025). Chalkophore-mediated respiratory oxidase flexibility controls M. tuberculosis virulence. eLife. 14. 1 indexed citations

Kochańczyk, Tomasz, et al.. (2024). Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature. 633(8028). 216–223. 14 indexed citations

Tan, Derek S., et al.. (2023). Direct conversion of amino acids to oxetanol bioisosteres via photoredox catalysis. Chemical Science. 14(38). 10524–10531. 10 indexed citations

Bourne, Christopher M., Megan M. Dacek, Thomas J. Gardner, et al.. (2023). Host Interactions with Engineered T-cell Micropharmacies. Cancer Immunology Research. 11(9). 1253–1265. 3 indexed citations

Gardner, Thomas J., Christopher M. Bourne, Dinali Wijewarnasuriya, et al.. (2021). Engineering CAR-T cells to activate small-molecule drugs in situ. Nature Chemical Biology. 18(2). 216–225. 58 indexed citations

Zhao, Shibin, Justyna Adamiak, Vincent Bonifay, et al.. (2020). Defining new chemical space for drug penetration into Gram-negative bacteria. Nature Chemical Biology. 16(12). 1293–1302. 83 indexed citations

Karimov, Rashad R., Derek S. Tan, & David Y. Gin. (2018). Synthesis of the hexacyclic triterpene core of the jujuboside saponins via tandem Wolff rearrangement–intramolecular ketene hetero-Diels–Alder reaction. Tetrahedron. 74(26). 3370–3383. 8 indexed citations

10.

Tan, Derek S., et al.. (2017). Family-level stereoselective synthesis and biological evaluation of pyrrolomorpholine spiroketal natural product antioxidants. Chemical Science. 8(5). 3687–3693. 12 indexed citations

11.

Davis, Tony D., et al.. (2016). Design, synthesis, and biological evaluation of α-hydroxyacyl-AMS inhibitors of amino acid adenylation enzymes. Bioorganic & Medicinal Chemistry Letters. 26(21). 5340–5345. 9 indexed citations

12.

Ji, Cheng, Indrajeet Sharma, Debarshi Pratihar, et al.. (2016). Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosa. ACS Chemical Biology. 11(11). 3061–3067. 43 indexed citations

13.

Evans, Christopher E. B., Indrajeet Sharma, Kanagalaghatta R. Rajashankar, et al.. (2015). Mechanism of MenE Inhibition by Acyl-Adenylate Analogues and Discovery of Novel Antibacterial Agents. Biochemistry. 54(42). 6514–6524. 25 indexed citations

14.

Fernández‐Tejada, Alberto, Constantine George, Nagavarakishore Pillarsetty, et al.. (2014). Development of a minimal saponin vaccine adjuvant based on QS-21. Nature Chemistry. 6(7). 635–643. 75 indexed citations

15.

Wenderski, Todd A., Christopher F. Stratton, Renato A. Bauer, Felix Kopp, & Derek S. Tan. (2014). Principal Component Analysis as a Tool for Library Design: A Case Study Investigating Natural Products, Brand-Name Drugs, Natural Product-Like Libraries, and Drug-Like Libraries. Methods in molecular biology. 1263. 225–242. 39 indexed citations

16.

Olsen, Shaun K., Allan D. Capili, Xuequan Lu, Derek S. Tan, & Christopher D. Lima. (2010). Active site remodelling accompanies thioester bond formation in the SUMO E1. Nature. 463(7283). 906–912. 160 indexed citations

17.

Ferreras, Julián A., Karen Stirrett, Xuequan Lu, et al.. (2008). Mycobacterial Phenolic Glycolipid Virulence Factor Biosynthesis: Mechanism and Small-Molecule Inhibition of Polyketide Chain Initiation. Chemistry & Biology. 15(1). 51–61. 72 indexed citations

18.

Tan, Derek S., et al.. (2005). Enantioselective synthesis of erythro-4-deoxyglycals as scaffolds for target- and diversity-oriented synthesis: new insights into glycal reactivity. Organic & Biomolecular Chemistry. 3(5). 798–798. 36 indexed citations

19.

Tan, Derek S.. (2005). Diversity-oriented synthesis: exploring the intersections between chemistry and biology. Nature Chemical Biology. 1(2). 74–84. 517 indexed citations breakdown →

20.

Ferreras, Julián A., Jae‐Sang Ryu, Federico A. Di Lello, Derek S. Tan, & Luis E. N. Quadri. (2005). Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis. Nature Chemical Biology. 1(1). 29–32. 236 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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