Christopher D. Lima

14.5k total citations · 3 hit papers
119 papers, 11.4k citations indexed

About

Christopher D. Lima is a scholar working on Molecular Biology, Oncology and Genetics. According to data from OpenAlex, Christopher D. Lima has authored 119 papers receiving a total of 11.4k indexed citations (citations by other indexed papers that have themselves been cited), including 112 papers in Molecular Biology, 24 papers in Oncology and 10 papers in Genetics. Recurrent topics in Christopher D. Lima's work include Ubiquitin and proteasome pathways (41 papers), RNA Research and Splicing (41 papers) and RNA and protein synthesis mechanisms (38 papers). Christopher D. Lima is often cited by papers focused on Ubiquitin and proteasome pathways (41 papers), RNA Research and Splicing (41 papers) and RNA and protein synthesis mechanisms (38 papers). Christopher D. Lima collaborates with scholars based in United States, Netherlands and Germany. Christopher D. Lima's co-authors include David Reverter, Stewart Shuman, Elena Mossessova, Laurent Cappadocia, Quansheng Liu, Kurt Januszyk, L. María Lois, Ali A. Yunus, Allan D. Capili and Elizabeth V. Wasmuth and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Christopher D. Lima

119 papers receiving 11.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

2010 922 citations Christopher D. Lima et al. profile →
Ulp1-SUMO Crystal Structure and Genetic Analysis Reveal Conserved Interactions and a Regulatory Element Essential for Cell Growth in Yeast

2000 586 citations Christopher D. Lima et al. profile →
Ubiquitin-like Protein Conjugation: Structures, Chemistry, and Mechanism

2017 412 citations Christopher D. Lima et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Christopher D. Lima United States	61	10.0k	2.3k	1.1k	1.0k	864	119	11.4k
Florian Gnad Germany	37	11.3k 1.1×	1.9k 0.9×	785 0.7×	909 0.9×	775 0.9×	54	13.6k
M. Groll Germany	61	12.2k 1.2×	4.2k 1.9×	1.4k 1.3×	892 0.9×	986 1.1×	254	14.5k
Rachel E. Klevit United States	62	10.7k 1.1×	2.0k 0.9×	1000 0.9×	2.3k 2.2×	731 0.8×	185	12.8k
Frauke Melchior Germany	52	11.3k 1.1×	3.1k 1.4×	944 0.8×	1.1k 1.1×	1.2k 1.4×	86	12.6k
Ulrich Hübscher Switzerland	60	10.2k 1.0×	1.8k 0.8×	607 0.5×	2.0k 1.9×	443 0.5×	224	12.1k
Ronald Frank Germany	46	6.6k 0.7×	764 0.3×	1.0k 0.9×	784 0.8×	962 1.1×	170	9.8k
Huib Ovaa Netherlands	68	11.7k 1.2×	4.4k 1.9×	1.9k 1.6×	906 0.9×	2.7k 3.1×	236	15.3k
Elena Conti Germany	63	11.2k 1.1×	922 0.4×	337 0.3×	702 0.7×	672 0.8×	174	13.3k
Stephen J. Smerdon United Kingdom	50	9.1k 0.9×	1.4k 0.6×	394 0.3×	826 0.8×	885 1.0×	99	11.3k

Countries citing papers authored by Christopher D. Lima

Since Specialization

Citations

This map shows the geographic impact of Christopher D. Lima's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher D. Lima with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher D. Lima more than expected).

Fields of papers citing papers by Christopher D. Lima

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher D. Lima. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher D. Lima. The network helps show where Christopher D. Lima may publish in the future.

Co-authorship network of co-authors of Christopher D. Lima

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher D. Lima. A scholar is included among the top collaborators of Christopher D. Lima based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher D. Lima. Christopher D. Lima is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kochańczyk, Tomasz, et al.. (2024). Structural basis for transthiolation intermediates in the ubiquitin pathway. Nature. 633(8028). 216–223. 14 indexed citations

Kochańczyk, Tomasz, М. Л. Фишман, & Christopher D. Lima. (2024). Chemical Tools for Probing the Ub/Ubl Conjugation Cascades. ChemBioChem. 26(1). e202400659–e202400659. 3 indexed citations

Puno, M Rhyan & Christopher D. Lima. (2022). Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex. Cell. 185(12). 2132–2147.e26. 30 indexed citations

Ginn, John D., Xiuju Jiang, Mayako Michino, et al.. (2021). Whole Cell Active Inhibitors of Mycobacterial Lipoamide Dehydrogenase Afford Selectivity over the Human Enzyme through Tight Binding Interactions. ACS Infectious Diseases. 7(2). 435–444. 5 indexed citations

Zinder, John C., et al.. (2021). Substrate discrimination and quality control require each catalytic activity of TRAMP and the nuclear RNA exosome. Proceedings of the National Academy of Sciences. 118(14). 10 indexed citations

Zinder, John C. & Christopher D. Lima. (2019). Reconstitution of S. cerevisiae RNA Exosome Complexes Using Recombinantly Expressed Proteins. Methods in molecular biology. 2062. 427–448. 1 indexed citations

Januszyk, Kurt, Quansheng Liu, & Christopher D. Lima. (2011). Activities of human RRP6 and structure of the human RRP6 catalytic domain. RNA. 17(8). 1566–1577. 82 indexed citations

Carvalho, Luiz Pedro S. de, Hong Zhao, Caitlyn Dickinson, et al.. (2010). Activity-Based Metabolomic Profiling of Enzymatic Function: Identification of Rv1248c as a Mycobacterial 2-Hydroxy-3-oxoadipate Synthase. Chemistry & Biology. 17(4). 323–332. 86 indexed citations

Gu, Meigang, Kanagalaghatta R. Rajashankar, & Christopher D. Lima. (2010). Structure of the Saccharomyces cerevisiae Cet1-Ceg1 mRNA Capping Apparatus. Structure. 18(2). 216–227. 26 indexed citations

10.

Lima, Christopher D., et al.. (2008). Chapter 10 Reconstitution of RNA Exosomes from Human and Saccharomyces cerevisiae. Methods in enzymology on CD-ROM/Methods in enzymology. 448. 185–210. 23 indexed citations

11.

Yunus, Ali A. & Christopher D. Lima. (2008). Purification of SUMO Conjugating Enzymes and Kinetic Analysis of Substrate Conjugation. Methods in molecular biology. 497. 167–186. 38 indexed citations

12.

Capili, Allan D. & Christopher D. Lima. (2007). Taking it step by step: mechanistic insights from structural studies of ubiquitin/ubiquitin-like protein modification pathways. Current Opinion in Structural Biology. 17(6). 726–735. 92 indexed citations

13.

Song, Li, Samita Bhattacharya, Ali A. Yunus, Christopher D. Lima, & Christian Schindler. (2006). Stat1 and SUMO modification. Blood. 108(10). 3237–3244. 40 indexed citations

14.

Gu, Meigang & Christopher D. Lima. (2005). Processing the message: structural insights into capping and decapping mRNA. Current Opinion in Structural Biology. 15(1). 99–106. 85 indexed citations

15.

Yunus, Ali A. & Christopher D. Lima. (2005). Purification and Activity Assays for Ubc9, the Ubiquitin‐Conjugating Enzyme for the Small Ubiquitin‐like Modifier SUMO. Methods in enzymology on CD-ROM/Methods in enzymology. 398. 74–87. 21 indexed citations

16.

Rajashankar, Kanagalaghatta R., Ruslana Bryk, R. Kniewel, et al.. (2005). Crystal Structure and Functional Analysis of Lipoamide Dehydrogenase from Mycobacterium tuberculosis. Journal of Biological Chemistry. 280(40). 33977–33983. 29 indexed citations

17.

Reverter, David, et al.. (2004). Structure of a Complex between Nedd8 and the Ulp/Senp Protease Family Member Den1. Journal of Molecular Biology. 345(1). 141–151. 73 indexed citations

18.

Jiao, Xinfu, et al.. (2004). Functional analysis of mRNA scavenger decapping enzymes. RNA. 10(9). 1412–1422. 71 indexed citations

19.

Hemelaar, Joris, Anna Borodovsky, Benedikt M. Kessler, et al.. (2003). Specific and Covalent Targeting of Conjugating and Deconjugating Enzymes of Ubiquitin-Like Proteins. Molecular and Cellular Biology. 24(1). 84–95. 176 indexed citations

20.

Lima, Christopher D.. (2003). CUE'd up for Monoubiquitin. Cell. 113(5). 554–556. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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