Dennis Ruff

439 citations

19 papers · 366 indexed · h-index 10

Impact in

Endocrinology, Diabetes and Metabolism top 10%
- Diabetes Treatment and Management
- Hormonal Regulation and Hypertension
- Diabetes Management and Research
Pharmacology
- Inflammatory mediators and NSAID effects

Papers in

Endocrinology, Diabetes and Metabolism 7
- Hormonal Regulation and Hypertension 4
- Diabetes Treatment and Management 3
Cardiology and Cardiovascular Medicine 7
- Blood Pressure and Hypertension Studies 4
- Renin-Angiotensin System Studies 2

Co-authors: Anne Turnage David R. Powell Joel Freiman Phillip Banks Arthur Sands Kenny Frazier Brian Zambrowicz Ike Ogbaa
Journals: Hypertension (2 papers)Clinical Therapeutics (2 papers)Endocrine Research (1 paper)Journal of Hypertension (1 paper)Diabetes (1 paper)
Partner nations: United States Switzerland Canada

In The Last Decade

Dennis Ruff

18 papers receiving 344 citations

Peers

Countries citing papers authored by Dennis Ruff

Since Specialization

Citations

This map shows the geographic impact of Dennis Ruff's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dennis Ruff with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dennis Ruff more than expected).

Fields of papers citing papers by Dennis Ruff

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dennis Ruff. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dennis Ruff. The network helps show where Dennis Ruff may publish in the future.

Co-authors

The 25 scholars most cited alongside Dennis Ruff, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Dennis Ruff Line = papers co-authored together Dennis Ruff links everyone, so they are left out of the graph.

All Works

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19 of 19 papers shown

#	Work
1	A phase I randomized, double‐blind, single subcutaneous dose escalation study to determine the safety, tolerability, and pharmacokinetics of rezafungin in healthy adult subjects Clinical and Translational Science ·Kenan Gu, Dennis Ruff, Cassandra Key, Marissa Thompson, Shoshanna Jiang, Taylor Sandison, Shawn Flanagan	2022	3
2	Two‐Part Phase 1 Multiple‐Ascending‐Dose Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of TRV734 in Healthy Adults Clinical Pharmacology in Drug Development ·Kimberly A. Ramos, Ian E. James, Franck Skobieranda, David G. Soergel, Dennis Ruff, Michael J. Fossler	2021	5
3	A First‐in‐Human Clinical Study With TRV734, an Orally Bioavailable G‐Protein–Biased Ligand at the μ‐Opioid Receptor Clinical Pharmacology in Drug Development ·Ian E. James, Franck Skobieranda, David G. Soergel, Kimberly A. Ramos, Dennis Ruff, Michael J. Fossler	2019	20
4	Rapid Dose Escalation Study of Praliciguat, a Soluble Guanylate Cyclase Stimulator, in Patients with Diabetes and Hypertension Diabetes ·John P. Hanrahan, James Wakefield, Phebe Wilson, Daniel P. Zimmer, Marina Mihova, Jennifer Chickering, Dennis Ruff, Michael L. Hall, Mark G. Currie, G. Todd Milne, Albert T. Profy	2018	1
5	A Randomized, Placebo‐Controlled, Multiple‐Ascending‐Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Soluble Guanylate Cyclase Stimulator Praliciguat in Healthy Subjects Clinical Pharmacology in Drug Development ·John P. Hanrahan, James Wakefield, Phebe Wilson, Marina Mihova, Jennifer Chickering, Dennis Ruff, Michael Hall, G. Todd Milne, Mark G. Currie, Albert T. Profy	2018	25
6	Multiple-Ascending-Dose Study of the Soluble Guanylate Cyclase Stimulator, IW-1701, in Healthy Subjects Blood ·Robert S. Mittleman, Phebe Wilson, Kristine Sykes, Marina Mihova, Jennifer Chickering, Dennis Ruff, Michael Hall, Todd Milne, Mark G. Currie, Yueh‐tyng Chien	2017	5
7	Abstract P493: Multiple-ascending-dose Study of IW-1973, a Soluble Guanylate Cyclase Stimulator Hypertension ·John P. Hanrahan, James Wakefield, Phebe Wilson, Marina Mihova, Jennifer Chickering, Dennis Ruff, Michael Hall, Todd Milne, Mark G. Currie, Albert T. Profy	2017	1
8	FIRST-IN-HUMAN SINGLE-ASCENDING-DOSE STUDY OF IW-1973, A NEW SOLUBLE GUANYLATE CYCLASE STIMULATOR Journal of the American College of Cardiology ·John P. Hanrahan, Albert T. Profy, Bernard J. Lavins, Dennis Ruff, Gabrielle Poirier, James Wakefield, Phebe Wilson, Michael Hall, Mark G. Currie	2016	3
9	Does GLP-1 suppress its own basal secretion? Endocrine Research ·Dariush Elahi, Dennis Ruff, Olga D. Carlson, Graydon S. Meneilly, Joel F. Habener, Josephine M. Egan	2015	9
10	Effects of LX4211, a Dual SGLT1/SGLT2 Inhibitor, Plus Sitagliptin on Postprandial Active GLP-1 and Glycemic Control in Type 2 Diabetes Clinical Therapeutics ·Brian Zambrowicz, Zhi‐Ming Ding, Ike Ogbaa, Kenny Frazier, Phillip Banks, Anne Turnage, Joel Freiman, Melinda Smith, Dennis Ruff, Arthur Sands, David R. Powell	2013	65
11	Effects of LX4211, a Dual Sodium-Dependent Glucose Cotransporters 1 and 2 Inhibitor, on Postprandial Glucose, Insulin, Glucagon-like Peptide 1, and Peptide Tyrosine Tyrosine in a Dose-Timing Study in Healthy Subjects Clinical Therapeutics ·Brian Zambrowicz, Ike Ogbaa, Kenny Frazier, Phillip Banks, Anne Turnage, Joel Freiman, Kristi A. Boehm, Dennis Ruff, David R. Powell, Arthur Sands	2013	52
12	Absence of an effect of T89 on the steady-state pharmacokinetics and pharmacodynamics of warfarin in healthy volunteers The Journal of Clinical Pharmacology ·Ping Wang, He Sun, Liu Yang, Lingyan Li, Jing Hao, Dennis Ruff, Zhi‐Xin Guo	2013	10
13	A randomized, placebo‐controlled, single and multiple dose study of intravenous thymosin β4 in healthy volunteers Annals of the New York Academy of Sciences ·Dennis Ruff, David Crockford, Gino Girardi, Yuxin Zhang	2010	36
14	Pharmacokinetics of Lumiracoxib in Plasma and Synovial Fluid Clinical Pharmacokinetics ·Graham Scott, Christiane Rordorf, Christine Reynolds, Jyoti Kalbag, Michael Looby, Slavica Milosavljev, Margaret L. Weaver, J P Huff, Dennis Ruff	2004	55
15	One-Year Study of Felodipine or Placebo for Stage 1 Isolated Systolic Hypertension Hypertension ·Henry R. Black, W.J. Elliott, Michael A. Weber, William H. Frishman, Joel A. Strom, Philip R. Liebson, Clara T. Hwang, Dennis Ruff, Rafael J. Montoro, Vincent DeQuattro, Danyi Zhang, Margo Schleman, Michael Klibaner	2001	22
16	Effective dose range of Candesartan cilexetil for systemic hypertension The American Journal of Cardiology ·T.Phillip Bell, Vincent DeQuattro, Kenneth C. Lasseter, Dennis Ruff, Joy Hardison, Daniel J. Cushing, Anne E Kezer, Eric L. Michelson	1999	12
17	Efficacy and tolerability of tasosartan, a novel angiotensin II receptor blocker: Results from a 10-week, double-blind, placebo-controlled, dose-titration study American Heart Journal ·Joel M. Neutel, Vardaman M. Buckalew, Steven G. Chrysant, William J. Mroczek, Dennis Ruff, Michael A. Weber	1999	9
18	Comparative effects of combination drug therapy regimens commencing with either losartan potassium, an angiotensin II receptor antagonist, or enalapril maleate for the treatment of severe hypertension Journal of Hypertension ·Dennis Ruff, Lisa P. Gazdick, Rayanne S. Berman, Allan I. Goldberg, Charles S. Sweet	1996	30
19	Pseudomembranous Colitis Following Low Dose Trimethoprim-Sulfamethoxazole The Journal of Urology ·Dennis Ruff, John S. Jaffe, Richard London, Joseph A. Candio	1985	3

About Dennis Ruff

Dennis Ruff is a scholar working on Endocrinology, Diabetes and Metabolism, Cardiology and Cardiovascular Medicine, Geriatrics and Gerontology, Physiology and Pharmacology, having authored 19 papers that have together received 366 indexed citations. Recurring topics across this work include Nitric Oxide and Endothelin Effects (5 papers), Hormonal Regulation and Hypertension (4 papers), Blood Pressure and Hypertension Studies (4 papers), Neuropeptides and Animal Physiology (3 papers), Diabetes Treatment and Management (3 papers), Pancreatic function and diabetes (2 papers), Renin-Angiotensin System Studies (2 papers) and Pharmaceutical Practices and Patient Outcomes (1 paper). The work is most often cited by research in Endocrinology, Diabetes and Metabolism (163 citations), Pharmacology (76 citations), Cardiology and Cardiovascular Medicine (100 citations), Biochemistry (20 citations) and Surgery (102 citations). Dennis Ruff has collaborated with scholars based in United States, Switzerland and Canada. Frequent co-authors include Anne Turnage, David R. Powell, Joel Freiman, Phillip Banks, Arthur Sands, Kenny Frazier, Brian Zambrowicz, Ike Ogbaa, David Crockford and Yuxin Zhang. Their work appears in journals such as Hypertension, Clinical Therapeutics, Endocrine Research, Journal of Hypertension and Diabetes.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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