Dene E. Ryan

10.7k total citations · 2 hit papers
106 papers, 9.5k citations indexed

About

Dene E. Ryan is a scholar working on Pharmacology, Molecular Biology and Oncology. According to data from OpenAlex, Dene E. Ryan has authored 106 papers receiving a total of 9.5k indexed citations (citations by other indexed papers that have themselves been cited), including 79 papers in Pharmacology, 44 papers in Molecular Biology and 31 papers in Oncology. Recurrent topics in Dene E. Ryan's work include Pharmacogenetics and Drug Metabolism (77 papers), Drug Transport and Resistance Mechanisms (27 papers) and Metabolomics and Mass Spectrometry Studies (22 papers). Dene E. Ryan is often cited by papers focused on Pharmacogenetics and Drug Metabolism (77 papers), Drug Transport and Resistance Mechanisms (27 papers) and Metabolomics and Mass Spectrometry Studies (22 papers). Dene E. Ryan collaborates with scholars based in United States, Switzerland and Poland. Dene E. Ryan's co-authors include Wayne Levin, Paul E. Thomas, Thomas K. H. Chang, Linda M. Reik, Alexander W. Wood, Anthony Y.H. Lu, Stelvio M. Bandiera, Susan West, Allan H. Conney and John E. Shively and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Biochemistry.

In The Last Decade

Dene E. Ryan

106 papers receiving 8.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

An improved staining procedure for the detection of the peroxidase activity of cytochrome P-450 on sodium dodecyl sulfate polyacrylamide gels

1976 952 citations Paul E. Thomas, Dene E. Ryan et al. profile →
Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene.

1979 516 citations Dene E. Ryan, Thomas K. H. Chang et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Dene E. Ryan United States	51	6.0k	3.7k	2.3k	1.4k	1.3k	106	9.5k
Laurence S. Kaminsky United States	51	5.6k 0.9×	3.0k 0.8×	2.6k 1.1×	1.1k 0.8×	1.1k 0.9×	157	9.6k
Anthony Y.H. Lu United States	48	5.4k 0.9×	3.0k 0.8×	2.4k 1.0×	872 0.6×	1.2k 0.9×	122	8.8k
Thomas K. H. Chang United States	59	6.4k 1.1×	3.9k 1.1×	3.0k 1.3×	1.1k 0.8×	1.3k 1.0×	222	12.1k
Tetsuya Kamataki Japan	56	7.9k 1.3×	5.5k 1.5×	4.0k 1.7×	2.0k 1.4×	1.4k 1.1×	364	13.7k
Ronald W. Estabrook United States	56	5.3k 0.9×	5.0k 1.3×	1.8k 0.8×	669 0.5×	1.5k 1.1×	135	10.7k
Paul E. Thomas United States	49	3.9k 0.6×	3.0k 0.8×	1.6k 0.7×	1.1k 0.8×	846 0.6×	154	8.4k
Yasushi Yamazoe Japan	53	5.0k 0.8×	3.7k 1.0×	2.4k 1.1×	1.8k 1.2×	913 0.7×	313	9.7k
M.D. Burke United Kingdom	42	5.2k 0.9×	3.3k 0.9×	2.2k 1.0×	1.6k 1.1×	941 0.7×	132	9.7k
Brian G. Lake United Kingdom	52	4.1k 0.7×	3.5k 1.0×	1.9k 0.8×	1.7k 1.2×	895 0.7×	291	9.6k
Brian Burchell United Kingdom	62	5.4k 0.9×	5.6k 1.5×	3.2k 1.4×	758 0.5×	662 0.5×	227	12.6k

Countries citing papers authored by Dene E. Ryan

Since Specialization

Citations

This map shows the geographic impact of Dene E. Ryan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dene E. Ryan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dene E. Ryan more than expected).

Fields of papers citing papers by Dene E. Ryan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dene E. Ryan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dene E. Ryan. The network helps show where Dene E. Ryan may publish in the future.

Co-authorship network of co-authors of Dene E. Ryan

This figure shows the co-authorship network connecting the top 25 collaborators of Dene E. Ryan. A scholar is included among the top collaborators of Dene E. Ryan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Dene E. Ryan. Dene E. Ryan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Greenfeder, Scott, Gordon Powers, David J. Shuster, et al.. (1995). Insertion of a Structural Domain of Interleukin (IL)-1β Confers Agonist Activity to the IL-1 Receptor Antagonist. Journal of Biological Chemistry. 270(38). 22460–22466. 26 indexed citations

Ryan, Dene E., Thomas K. H. Chang, Wayne Levin, et al.. (1993). Monoclonal Antibodies of Differentiating Specificities as Probes of Cytochrome P450h (2C11). Archives of Biochemistry and Biophysics. 301(2). 282–293. 12 indexed citations

Ryan, Dene E. & Wayne Levin. (1990). Purification and characterization of hepatic microsomal cytochrome P-450. Pharmacology & Therapeutics. 45(2). 153–239. 335 indexed citations

Parkinson, A., Thomas K. H. Chang, Dene E. Ryan, et al.. (1988). Induction of rat liver microsomal cytochrome P-450 isozymes and epoxide hydrolase by a series of 4′-substituted-2,3,4,5-tetrachlorobiphenyls. Toxicology. 53(2-3). 289–300. 10 indexed citations

Kutty, R. Krishnan, et al.. (1988). Rat liver cytochrome P-450b, P-420b, and P-420c are degraded to biliverdin by heme oxygenase. Archives of Biochemistry and Biophysics. 260(2). 638–644. 75 indexed citations

Chang, Thomas K. H., Stelvio M. Bandiera, S L Maines, Dene E. Ryan, & Wayne Levin. (1987). Regulation of rat liver cytochrome P450j, a high affinity N-nitrosodimethylamine demethylase (NDMAD). Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States). 2 indexed citations

Wrighton, Steven, Paul E. Thomas, Dene E. Ryan, & Wayne Levin. (1987). Purification and characterization of ethanol-inducible human hepatic cytochrome P-450HLj. Archives of Biochemistry and Biophysics. 258(1). 292–297. 97 indexed citations

Levin, Wayne, Paul E. Thomas, Dene E. Ryan, & Alexander W. Wood. (1987). Isozyme specificity of testosterone 7α-hydroxylation in rat hepatic microsomes: Is cytochrome P-450a the sole catalyst?. Archives of Biochemistry and Biophysics. 258(2). 630–635. 36 indexed citations

Thomas, Paul E., et al.. (1987). Regulation of cytochrome P-450j, a high-affinity N-nitrosodimethylamine demethylase, in rat hepatic microsomes. Biochemistry. 26(8). 2280–2289. 187 indexed citations

10.

Pantuck, Eugene J., Carol B. Pantuck, Dene E. Ryan, & Allan H. Conney. (1985). Inhibition and Stimulation of Enflurane Metabolism in the Rat Following a Single Dose or Chronic Administration of Ethanol. Anesthesiology. 62(3). 255–262. 15 indexed citations

11.

Safe, Stephen, Stelvio M. Bandiera, T. Sawyer, et al.. (1985). PCBs: structure–function relationships and mechanism of action. Environmental Health Perspectives. 60. 47–56. 46 indexed citations

12.

Parkinson, Andrew, Paul E. Thomas, Dene E. Ryan, et al.. (1983). Differential time course of induction of rat liver microsomal cytochrome P-450 isozymes and epoxide hydrolase by Aroclor 1254. Archives of Biochemistry and Biophysics. 225(1). 203–215. 64 indexed citations

13.

Vyas, Kamlesh P., Wayne Levin, Haruhiko Yagi, et al.. (1982). Stereoselective metabolism of the (+)- and (-)-enantiomers of trans-1,2-dihydroxy-1,2-dihydrochrysene to bay-region 1,2-diol-3,4-epoxide diastereomers by rat liver enzymes.. Molecular Pharmacology. 22(1). 182–189. 25 indexed citations

14.

Vlasuk, G P, Curtis J. Omiecinski, Edward Bresnick, et al.. (1982). Multiple, immunoidentical forms of phenobarbital-induced rat liver cytochromes P-450 are encoded by different mRNAs.. Journal of Biological Chemistry. 257(8). 4023–4026. 61 indexed citations

15.

Bresnick, Edward, et al.. (1981). Administration of 3-methylcholanthrene to rats increases the specific hybridizable mRNA coding for cytochrome P-450c.. Proceedings of the National Academy of Sciences. 78(7). 4083–4087. 42 indexed citations

16.

Nordqvist, Marianne, Dhiren R. Thakker, Kamlesh P. Vyas, et al.. (1981). Metabolism of Chrysene and Phenanthrene to Bay-Region Diol Epoxides by Rat Liver Enzymes. Molecular Pharmacology. 19(1). 168–178. 86 indexed citations

17.

Nordqvist, Marianne, Dhiren R. Thakker, Wayne Levin, et al.. (1979). The Highly Tumorigenic 3,4-Dihydrodiol Is a Principal Metabolite Formed from Dibenzo[a,h]anthracene by Liver Enzymes. Molecular Pharmacology. 16(2). 643–655. 30 indexed citations

18.

Thomas, Paul E., et al.. (1979). Preparation of monospecific antibodies against two forms of rat liver cytochrome P-450 and quantitation of these antigens in microsomes. Archives of Biochemistry and Biophysics. 192(2). 524–532. 164 indexed citations

19.

Wood, Alexander W., Wayne Levin, Paul E. Thomas, et al.. (1978). Metabolic activation of dibenzo(a,h)anthracene and its dihydrodiols to bacterial mutagens.. PubMed. 38(7). 1967–73. 52 indexed citations

20.

Lu, Anthony Y.H., Susan West, Dene E. Ryan, & Wayne Levin. (1973). CHARACTERIZATION OF PARTIALLY PURIFIED CYTOCHROMES P-450 AND P-448 FROM RAT LIVER MICROSOMES. Drug Metabolism and Disposition. 1(1). 29–39. 19 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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