David V. Schaffer

27.6k total citations · 8 hit papers
284 papers, 21.0k citations indexed

About

David V. Schaffer is a scholar working on Molecular Biology, Genetics and Biomedical Engineering. According to data from OpenAlex, David V. Schaffer has authored 284 papers receiving a total of 21.0k indexed citations (citations by other indexed papers that have themselves been cited), including 196 papers in Molecular Biology, 97 papers in Genetics and 52 papers in Biomedical Engineering. Recurrent topics in David V. Schaffer's work include Virus-based gene therapy research (89 papers), RNA Interference and Gene Delivery (59 papers) and CRISPR and Genetic Engineering (58 papers). David V. Schaffer is often cited by papers focused on Virus-based gene therapy research (89 papers), RNA Interference and Gene Delivery (59 papers) and CRISPR and Genetic Engineering (58 papers). David V. Schaffer collaborates with scholars based in United States, South Korea and Russia. David V. Schaffer's co-authors include Melissa A. Kotterman, Brian K. Kaspar, John G. Flannery, Kevin E. Healy, James T. Koerber, Ravi S. Kane, Deniz Dalkara, Krishanu Saha, Albert J. Keung and Adam P. Arkin and has published in prestigious journals such as Nature, Cell and Chemical Reviews.

In The Last Decade

David V. Schaffer

276 papers receiving 20.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Substrate Modulus Directs Neural Stem Cell Behavior

2008 862 citations Krishanu Saha, Albert J. Keung et al. profile →
A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons

2016 830 citations David V. Schaffer et al. profile →
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

2002 643 citations Brian K. Kaspar, David V. Schaffer et al. profile →
Engineering adeno-associated viruses for clinical gene therapy

2014 599 citations David V. Schaffer et al. profile →
In Vivo–Directed Evolution of a New Adeno-Associated Virus for Therapeutic Outer Retinal Gene Delivery from the Vitreous

2013 555 citations Deniz Dalkara, Leah C. Byrne et al. profile →
The influence of hydrogel modulus on the proliferation and differentiation of encapsulated neural stem cells

2009 540 citations David V. Schaffer et al. profile →
Biophysical regulation of epigenetic state and cell reprogramming

2013 386 citations David V. Schaffer et al. profile →
Viral Vectors for Gene Therapy: Translational and Clinical Outlook

2015 351 citations David V. Schaffer et al. profile →

Peers

Countries citing papers authored by David V. Schaffer

Since Specialization

Citations

This map shows the geographic impact of David V. Schaffer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David V. Schaffer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David V. Schaffer more than expected).

Fields of papers citing papers by David V. Schaffer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David V. Schaffer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David V. Schaffer. The network helps show where David V. Schaffer may publish in the future.

Co-authorship network of co-authors of David V. Schaffer

This figure shows the co-authorship network connecting the top 25 collaborators of David V. Schaffer. A scholar is included among the top collaborators of David V. Schaffer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David V. Schaffer. David V. Schaffer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Nickase fidelity drives EvolvR-mediated diversification in mammalian cells 2025 ·Nature Communications ·(unknown), (unknown), (unknown), Jianguo Guan, (unknown), David V. Schaffer, John E. Dueber	1
2	Dynamic light-responsive RhoA activity regulates mechanosensitive stem cell fate decision in 3D matrices 2024 ·Biomaterials Advances ·Jieung Baek, Sanjay Kumar, David V. Schaffer	2
3	Substrate stress relaxation regulates neural stem cell fate commitment 2024 ·Proceedings of the National Academy of Sciences ·(unknown), Camille Fulmore, David V. Schaffer, Sanjay Kumar	10
4	Effects of Molecular Size on Resolution in Charge Detection Mass Spectrometry 2022 ·Analytical Chemistry ·Conner C. Harper, Zachary M. Miller, Hyun‐Cheol Lee, Amanda J. Bischoff, Matthew B. Francis, David V. Schaffer, Evan R. Williams	21
5	Apodization Specific Fitting for Improved Resolution, Charge Measurement, and Data Analysis Speed in Charge Detection Mass Spectrometry 2022 ·Journal of the American Society for Mass Spectrometry ·Zachary M. Miller, Conner C. Harper, Hyun‐Cheol Lee, Amanda J. Bischoff, Matthew B. Francis, David V. Schaffer, Evan R. Williams	19
6	scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution 2021 ·eLife ·Bilge Esin Öztürk, Molly Johnson, Michael Kleyman, (unknown), Jing He, (unknown), (unknown), Meike Visel, Valérie Dufour, Simone Iwabe, (unknown), Geoffrey K. Aguirre, José‐Alain Sahel, David V. Schaffer, Andreas R. Pfenning, John G. Flannery, William A. Beltran, William R. Stauffer, Leah C. Byrne	41
7	High-Throughput Discovery of Targeted, Minimally Complex Peptide Surfaces for Human Pluripotent Stem Cell Culture 2021 ·ACS Biomaterials Science & Engineering ·(unknown), (unknown), Caroline Sugnaux, (unknown), (unknown), Douglas S. Clark, Kevin E. Healy, David V. Schaffer	6
8	High-throughput 3D screening for differentiation of hPSC-derived cell therapy candidates 2020 ·Science Advances ·(unknown), Xiaoping Bao, (unknown), (unknown), (unknown), Jonathan S. Dordick, Douglas S. Clark, David V. Schaffer	6
9	The Spectrin-Actin-Based Periodic Cytoskeleton as a Conserved Nanoscale Scaffold and Ruler of the Neural Stem Cell Lineage 2018 ·Cell Reports ·(unknown), Rui Yan, Li Wan, Nicole Repina, David V. Schaffer, Ke Xu	29
10	Microelastic mapping of the rat dentate gyrus 2016 ·Royal Society Open Science ·Tomás Luque, Michael S. Kang, David V. Schaffer, Sanjay Kumar	26
11	A Global Assessment of Stem Cell Engineering 2014 ·Tissue Engineering Part A ·Jeanne F. Loring, Todd C. McDevitt, Sean P. Palecek, David V. Schaffer, Peter W. Zandstra, Robert M. Nerem	5
12	Mutual Information Analysis Reveals Coevolving Residues in Tat That Compensate for Two Distinct Functions in HIV-1 Gene Expression 2012 ·Journal of Biological Chemistry ·Siddharth S. Dey, Yuhua Xue, Marcin P. Joachimiak, Gregory D. Friedland, John Burnett, Qiang Zhou, Adam P. Arkin, David V. Schaffer	9
13	In vivo imaging of ganglion cell physiology in macaque fovea using a calcium indicator 2012 ·Journal of Vision ·Lu Yin, B. Masella, Deniz Dalkara, John G. Flannery, David V. Schaffer, David R. Williams, William H. Merigan	2
14	Developing Photoreceptor Targeted AAV Variant by Directed Evolution 2011 ·Investigative Ophthalmology & Visual Science ·Deniz Dalkara, R. R. Klimczak, Meike Visel, (unknown), David V. Schaffer, John G. Flannery	2
15	Protocols for Adult Stem Cells 2010 ·Methods in molecular biology ·Irina M. Conboy, David V. Schaffer, Mary Helen Barcellos‐Hoff, Song Li	6
16	Combinatorial Latency Reactivation for HIV-1 Subtypes and Variants 2010 ·Journal of Virology ·John Burnett, Kwang‐il Lim, (unknown), John J. Rossi, David V. Schaffer, Adam P. Arkin	91
17	Akt Increases Sox2 Expression in Adult Hippocampal Neural Progenitor Cells, but Increased Sox2 Does Not Promote Proliferation 2010 ·Stem Cells and Development ·Joseph Peltier, Anthony Conway, Albert J. Keung, David V. Schaffer	25
18	Directed evolution of adeno-associated virus to an infectious respiratory virus 2009 ·Proceedings of the National Academy of Sciences ·Katherine J. D. A. Excoffon, James T. Koerber, David D. Dickey, Matthew Murtha, Shaf Keshavjee, Brian K. Kaspar, Joseph Zabner, David V. Schaffer	135
19	Computational Models of the Notch Network Elucidate Mechanisms of Context-dependent Signaling 2009 ·PLoS Computational Biology ·Smita Agrawal, Colin Archer, David V. Schaffer	55
20	Signal dynamics in Sonic hedgehog tissue patterning 2006 ·Development ·Krishanu Saha, David V. Schaffer	91

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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