David M. Shepherd

4.6k citations

93 papers · 3.8k indexed · 1 hit paper · h-index 29

Impact in

Immunology top 1%
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- Immune Response and Inflammation
Biological Psychiatry top 5%

Papers in

Biological Psychiatry 4
Immunology 32
- T-cell and B-cell Immunology 18
- Immunotherapy and Immune Responses 12
- Immune Cell Function and Interaction 9
- Immune Response and Inflammation 7

Co-authors: Alejandro Aruffo Michael Roy Randolph J. Noelle Jenna M. Benson R J Noelle J A Ledbetter Ivan Stamenkovic G.B. West
Journals: Journal of Pharmacy and Pharmacology (10 papers)Nature (8 papers)The Journal of Immunology (8 papers)Toxicological Sciences (7 papers)Canadian Journal of Microbiology (5 papers)
Partner nations: United States United Kingdom Canada

In The Last Decade

David M. Shepherd

91 papers receiving 3.5k citations

Hit Papers

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A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells. 1992 · 698 citations

Peers

Countries citing papers authored by David M. Shepherd

Since Specialization

Citations

This map shows the geographic impact of David M. Shepherd's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David M. Shepherd with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David M. Shepherd more than expected).

Fields of papers citing papers by David M. Shepherd

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David M. Shepherd. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David M. Shepherd. The network helps show where David M. Shepherd may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David M. Shepherd, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David M. Shepherd Line = papers co-authored together David M. Shepherd links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Aryl hydrocarbon receptor signaling modifies Toll-like receptor-regulated responses in human dendritic cells Archives of Toxicology ·Sarah Y. Kado, W. L. William Chang, Abdoljabbar Asadi, 李秀豪, David M. Shepherd, Christoph F. A. Vogel	2016	50
2	Acute Exposure to Crystalline Silica Reduces Macrophage Activation in Response to Bacterial Lipoproteins Frontiers in Immunology ·Gillian Beamer, In Sil Jang, Forrest Jessop, David M. Shepherd, Celine A. Beamer	2016	19
3	In vitro Exposure to the Herbicide Atrazine Inhibits T Cell Activation, Proliferation, and Cytokine Production and Significantly Increases the Frequency of Foxp3+ Regulatory T Cells Toxicological Sciences ·Alain Puech, Tiffany R. Emmons, Nhu Thi Huynh Truong, Radu Macarie, David M. Shepherd, Scott A. Wetzel	2014	28
4	Aryl Hydrocarbon Receptor (AhR) Regulates Silica-Induced Inflammation But Not Fibrosis Toxicological Sciences ·Celine A. Beamer, In Sil Jang, David M. Shepherd	2012	38
5	Inhibition of TLR Ligand- and Interferon Gamma-Induced Murine Microglial Activation by Panax Notoginseng Journal of Neuroimmune Pharmacology ·Celine A. Beamer, David M. Shepherd	2011	17
6	Echinacea purpurea extracts modulate murine dendritic cell fate and function Food and Chemical Toxicology ·Jenna M. Benson, I. E. Starobin, Yanisleidy Orozco Roque, Cynthia A. Wenner, Chieko Fukushima, Nadja B. Cech, David M. Shepherd	2010	36
7	Functional and phenotypic effects of AhR activation in inflammatory dendritic cells Toxicology and Applied Pharmacology ·Jaishree Bankoti, A. Cailar, Jolanda Vehar, David M. Shepherd	2010	109
8	Anti-Inflammatory Effects of Natural Product Formulations on Murine Macrophages Journal of Dietary Supplements ·Jenna M. Benson, E. Bernhardt, Natalie Cooper, А.А. Гладышева, Jerry R. Smith, David M. Shepherd	2010	2
9	Panax notoginseng attenuates LPS-induced pro-inflammatory mediators in RAW264.7 cells Journal of Ethnopharmacology ·Yanisleidy Orozco Roque, Séverine Navarro, Jerry R. Smith, David M. Shepherd	2006	152
10	CTIP1 and CTIP2 are differentially expressed during mouse embryogenesis Gene Expression Patterns ·Mark Leid, Jane E. Ishmael, Dorina Avram, David M. Shepherd, Valérie Fraulob, Pascal Dollé	2004	121
11	Anti-CD40 Treatment of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-Exposed C57Bl/6 Mice Induces Activation of Antigen Presenting Cells Yet Fails to Overcome TCDD-Induced Suppression of Allograft Immunity Toxicology and Applied Pharmacology ·David M. Shepherd, Linda B. Steppan, Olaf R. Hedstrom, Nancy I. Kerkvliet	2001	23
12	The Effects of TCDD on the Activation of Ovalbumin (OVA)-Specific DO11.10 Transgenic CD4+ T cells in Adoptively Transferred Mice Toxicological Sciences ·David M. Shepherd	2000	50
13	Disruption of CD154:CD40 Blocks Generation of Allograft Immunity Without Affecting APC Activation The Journal of Immunology ·David M. Shepherd, Nancy I. Kerkvliet	1999	33
14	In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39. The Journal of Experimental Medicine ·Teresa M. Foy, David M. Shepherd, Fiona H. Durie, Alejandro Aruffo, J A Ledbetter, Randolph J. Noelle	1993	308
15	In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions. The Journal of Experimental Medicine ·Alfons J. van den Eertwegh, Randolph J. Noelle, Michael Roy, David M. Shepherd, Alejandro Aruffo, J A Ledbetter, W J Boersma, Eric Claassen	1993	218
16	Cognate interactions between helper T cells and B cells. V. Reconstitution of T helper cell function using purified plasma membranes from activated Th1 and Th2 T helper cells and lymphokines The Journal of Immunology ·Randolph J. Noelle, John R. Daum, William C. Bartlett, Jesse McCann, David M. Shepherd	1991	76
17	Ferrous fumarate fortification of a chocolate drink powder British Journal Of Nutrition ·Richard F. Hurrell, Manju B. Reddy, Sandra A. Dassenko, James D. Cook, David M. Shepherd	1991	61
18	Early Diagnosis of Tyrosinemia Type II American Journal of Ophthalmology ·David G. Heidemann, Steven P. Dunn, Erawati V. Bawle, David M. Shepherd	1989	7
19	Gastric mucosal histamine and histamine methytltransferase in patients with duodenal ulcer. Gut ·N. R. Peden, Helen Callachan, David M. Shepherd, K. G. Wormsley	1982	19
20	CHEMISTRY OF COUMARIN ANTICOAGULANT DRUGS British Medical Bulletin ·R. B. Hunter, David M. Shepherd	1955	6

About David M. Shepherd

David M. Shepherd is a scholar working on Biological Psychiatry, Immunology, Clinical Biochemistry, Biochemistry and Physiology, having authored 93 papers that have together received 3.8k indexed citations. Recurring topics across this work include T-cell and B-cell Immunology (18 papers), Immunotherapy and Immune Responses (12 papers), Polyamine Metabolism and Applications (11 papers), Enzyme function and inhibition (9 papers), Immune Cell Function and Interaction (9 papers), Immune Response and Inflammation (7 papers), Amino Acid Enzymes and Metabolism (6 papers) and Metabolism and Genetic Disorders (6 papers). The work is most often cited by research in Immunology (1.8k citations), Biological Psychiatry (124 citations), Immunology and Allergy (176 citations), Biotechnology (202 citations) and Pharmacology (202 citations). David M. Shepherd has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include Alejandro Aruffo, Michael Roy, Randolph J. Noelle, Jenna M. Benson, R J Noelle, J A Ledbetter, Ivan Stamenkovic, G.B. West, Celine A. Beamer and J A Ledbetter. Their work appears in journals such as Journal of Pharmacy and Pharmacology, Nature, The Journal of Immunology, Toxicological Sciences and Canadian Journal of Microbiology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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