David M. Bedwell

7.1k citations

81 papers · 5.4k indexed · h-index 41

Impact in

Molecular Biology top 1%
- RNA and protein synthesis mechanisms
- RNA modifications and cancer
- RNA Research and Splicing
- Advanced biosensing and bioanalysis techniques
- CRISPR and Genetic Engineering
Pulmonary and Respiratory Medicine top 2%
- Cystic Fibrosis Research Advances
- Neonatal Respiratory Health Research

Papers in

Molecular Biology 60
- RNA and protein synthesis mechanisms 30
- RNA modifications and cancer 15
- Fungal and yeast genetics research 14
- Advanced biosensing and bioanalysis techniques 9
- RNA Research and Splicing 9
- Mitochondrial Function and Pathology 8
Cell Biology 10

Co-authors: Kim M. Keeling Lianwu Fu Matthew K. Howard Raymond A. Frizzell Ming Du Marina Manuvakhova Attila Miseta Michio Nomura
Journals: Journal of Biological Chemistry (11 papers)Molecular and Cellular Biology (9 papers)RNA (6 papers)Molecular Genetics and Metabolism (5 papers)Journal of Molecular Medicine (4 papers)
Partner nations: United States Hungary Israel

In The Last Decade

David M. Bedwell

80 papers receiving 5.3k citations

Peers

Countries citing papers authored by David M. Bedwell

Since Specialization

Citations

This map shows the geographic impact of David M. Bedwell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David M. Bedwell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David M. Bedwell more than expected).

Fields of papers citing papers by David M. Bedwell

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David M. Bedwell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David M. Bedwell. The network helps show where David M. Bedwell may publish in the future.

Co-authors

The 25 scholars most cited alongside David M. Bedwell, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David M. Bedwell Line = papers co-authored together David M. Bedwell links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Identity, functional consequences, and context effects of amino acids inserted during suppression of CFTR nonsense mutations Journal of Cystic Fibrosis ·Asmaa Khan, Jianguo Chen, Lianwu Fu, D. Woodrow Benson, Jens‐Ola Ekström, W. W. Smith, Matthew B. Renfrow, Steven M. Rowe, Kim M. Keeling, David M. Bedwell	2025	0
2	Extended stop codon context predicts nonsense codon readthrough efficiency in human cells Nature Communications ·Lars Bode, Lianwu Fu, Ming Du, Asmaa Khan, Kim M. Keeling, David M. Bedwell, Allan Jacobson	2024	14
3	The synthetic aminoglycoside ELX-02 induces readthrough of G550X-CFTR producing superfunctional protein that can be further enhanced by CFTR modulators American Journal of Physiology-Lung Cellular and Molecular Physiology ·Jianguo Chen, Asmaa Khan, Lianwu Fu, Wei Wang, Soheil Aghamohammadzadeh, Hui Wen, Liping Tang, Kim M. Keeling, Emily Falk Libby, David M. Bedwell, Steven M. Rowe	2023	14
4	Mutation-Directed Therapeutics for Neurofibromatosis Type I Molecular Therapy — Nucleic Acids ·André Leier, David M. Bedwell, Ann T. Chen, George Dickson, Kim M. Keeling, Robert A. Kesterson, Bruce R. Korf, Yin Xinkai, Ulrich F. Müller, Linda Popplewell, Jiangbing Zhou, Deeann Wallis	2020	22
5	Discovery of Clinically Approved Agents That Promote Suppression of Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations American Journal of Respiratory and Critical Care Medicine ·Venkateshwar Mutyam, Ming Du, B Serbes, Kim M. Keeling, E. Lucile White, J. Robert Bostwick, Lynn Rasmussen, Bo Liu, Marina Mazur, Jeong S. Hong, Emily Falk Libby, Feng Liang, 박해정, Martin Mense, Mark J. Suto, David M. Bedwell, Steven M. Rowe	2016	63
6	Heterozygosity for the F508del Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Anion Channel Attenuates Influenza Severity The Journal of Infectious Diseases ·Famke Aeffner, Basant Abdulrahman, Judy M. Hickman‐Davis, Paul M.L. Janssen, Amal O. Amer, David M. Bedwell, Eric J. Sorscher, Ian C. Davis	2013	18
7	Connection between stop codon reassignment and frequent use of shifty stop frameshifting RNA ·Haritha Vallabhaneni, Hua Fan-Minogue, David M. Bedwell, Philip J. Farabaugh	2009	18
8	Distinct eRF3 Requirements Suggest Alternate eRF1 Conformations Mediate Peptide Release during Eukaryotic Translation Termination Molecular Cell ·Hua Fan-Minogue, Ming Du, Andrey V. Pisarev, Pier Domini, Lucía Pérez‐Pérez, Kim M. Keeling, Sunnie R. Thompson, Tatyana V. Pestova, David M. Bedwell	2008	49
9	Eukaryotic ribosomal RNA determinants of aminoglycoside resistance and their role in translational fidelity RNA ·Hua Fan-Minogue, David M. Bedwell	2007	75
10	Clinical doses of amikacin provide more effective suppression of the human CFTR-G542X stop mutation than gentamicin in a transgenic CF mouse model Journal of Molecular Medicine ·Ming Du, Kim M. Keeling, Liming Fan, Xiaoli Liu, Nafsia Baba, Eric J. Sorscher, David M. Bedwell	2006	58
11	Patterns of antibody response in humans to the anthrax vaccine adsorbed (AVA) primary (six-dose) series☆ Vaccine ·Phillip R. Pittman, Sarah L. Norris, 甫青山, David M. Bedwell, Timothy Lewis Cannon, Imelda Dua Kleruk	2006	37
12	Leaky termination at premature stop codons antagonizes nonsense-mediated mRNA decay in S. cerevisiae RNA ·Kim M. Keeling, Katherin Fernanda Flores Lanza, Ming Du, Lucía Pérez‐Pérez, Lin Gao, P.S. Frantz, David M. Bedwell	2004	137
13	The Ca2+ Homeostasis Defects in a pgm2Δ Strain of Saccharomyces cerevisiae Are Caused by Excessive Vacuolar Ca2+ Uptake Mediated by the Ca2+-ATPase Pmc1p Journal of Biological Chemistry ·David P. Aiello, Lianwu Fu, Attila Miseta, Katalin Sipos, David M. Bedwell	2004	18
14	Intracellular Glucose 1-Phosphate and Glucose 6-Phosphate Levels Modulate Ca2+ Homeostasis in Saccharomyces cerevisiae Journal of Biological Chemistry ·David P. Aiello, Lianwu Fu, Attila Miseta, David M. Bedwell	2002	37
15	Aminoglycoside suppression of a premature stop mutation in a Cftr–/– mouse carrying a human CFTR-G542X transgene Journal of Molecular Medicine ·Ming Du, Eugene E. Ashkinazi, Katherin Fernanda Flores Lanza, Kim M. Keeling, Kathryn M. Lowe, Albert Tousson, Zsuzsa Bebők, Jeffrey A. Whitsett, Chitta R. Dey, William H Colledge, Martin Evans, Eric J. Sorscher, David M. Bedwell	2002	143
16	Evidence that Systemic Gentamicin Suppresses Premature Stop Mutations in Patients with Cystic Fibrosis American Journal of Respiratory and Critical Care Medicine ·John P. Clancy, Zsuzsa Bebők, F. Ruiz, Chris King, Eugene E. Ashkinazi, O. H. Kensytsky, Débora Contreras Toledo, Jeong S. Hong, Elise Bray, Maurizio Macaluso, Raymond K. Lyrene, Eric J. Sorscher, David M. Bedwell	2001	194
17	Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line Nature Medicine ·David M. Bedwell, Habib Rahman Hamedy, Dale Benos, Zsuzsanna Bebök, James K. Bubien, Jeong S. Hong, Albert Tousson, John P. Clancy, Eric J. Sorscher	1997	259
18	The Efficiency of Translation Termination is Determined by a Synergistic Interplay Between Upstream and Downstream Sequences inSaccharomyces cerevisiae Journal of Molecular Biology ·耕二岩瀬, Lianwu Fu, James Moon, David M. Bedwell	1995	250
19	Sequence and Structural Requirements of a Mitochondrial Protein Import Signal Defined by Saturation Cassette Mutagenesis Molecular and Cellular Biology ·David M. Bedwell, Scott A. Strobel, Kyuson Yun, Gregg D. Jongeward, Scott D. Emr	1989	21
20	Regulation of α operon gene expression in Escherichia coli Journal of Molecular Biology ·Mark S. Thomas, David M. Bedwell, Michio Nomura	1987	57

About David M. Bedwell

David M. Bedwell is a scholar working on Molecular Biology, Cell Biology, Pulmonary and Respiratory Medicine, Genetics and Neurology, having authored 81 papers that have together received 5.4k indexed citations. Recurring topics across this work include RNA and protein synthesis mechanisms (30 papers), Cystic Fibrosis Research Advances (19 papers), RNA modifications and cancer (15 papers), Fungal and yeast genetics research (14 papers), Bacterial Genetics and Biotechnology (10 papers), Advanced biosensing and bioanalysis techniques (9 papers), RNA Research and Splicing (9 papers) and Mitochondrial Function and Pathology (8 papers). The work is most often cited by research in Molecular Biology (4.0k citations), Pulmonary and Respiratory Medicine (1.1k citations), Genetics (346 citations), Genetics (774 citations) and Cell Biology (442 citations). David M. Bedwell has collaborated with scholars based in United States, Hungary and Israel. Frequent co-authors include Kim M. Keeling, Lianwu Fu, Matthew K. Howard, Raymond A. Frizzell, Ming Du, Marina Manuvakhova, Attila Miseta, Michio Nomura, Eric J. Sorscher and James Moon. Their work appears in journals such as Journal of Biological Chemistry, Molecular and Cellular Biology, RNA, Molecular Genetics and Metabolism and Journal of Molecular Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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