William R. Skach

7.3k citations

87 papers · 5.3k indexed · 1 hit paper · h-index 42

Molecular Biology top 2%
Pulmonary and Respiratory Medicine top 1%
Cell Biology top 1%
Genetics top 5%
Epidemiology top 10%

Co-authors: A.S. Verkman Tonghui Ma Hajime Hasegawa Jeffrey L. Brodsky Vishwanath R. Lingappa Arthur E. Johnson Zhongying Yang Michael A. Matthay
Topics: Cystic Fibrosis Research Advances (23 papers)RNA and protein synthesis mechanisms (22 papers)Ion Transport and Channel Regulation (19 papers)
Cited by: Cell Biology Molecular Biology Pulmonary and Respiratory Medicine
Journals: Science Cell Journal of Biological Chemistry
Partner nations: United States United Kingdom Canada

In The Last Decade

William R. Skach

87 papers receiving 5.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations

2016 422 citations William R. Skach et al. Molecular Biology of the Cell profile →

Peers

Countries citing papers authored by William R. Skach

Since Specialization

Citations

This map shows the geographic impact of William R. Skach's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William R. Skach with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William R. Skach more than expected).

Fields of papers citing papers by William R. Skach

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William R. Skach. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William R. Skach. The network helps show where William R. Skach may publish in the future.

Co-authorship network of co-authors of William R. Skach

This figure shows the co-authorship network connecting the top 25 collaborators of William R. Skach. A scholar is included among the top collaborators of William R. Skach based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William R. Skach. William R. Skach is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Engineered transfer RNAs for suppression of premature termination codons 2019 ·Nature Communications ·John D. Lueck,Jae Seok Yoon,Alfredo Perales‐Puchalt,(unknown),Daniel T. Infield,Mark A. Behlke,(unknown),David B. Weiner,William R. Skach,Paul B. McCray,Christopher A. Ahern	105
2	Translational tuning optimizes nascent protein folding in cells 2015 ·Science ·Soo Jung Kim,Jae Seok Yoon,Hideki Shishido,Zhongying Yang,(unknown),José M. Barral,William R. Skach	157
3	Cotranslational Stabilization of Sec62/63 within the ER Sec61 Translocon Is Controlled by Distinct Substrate-Driven Translocation Events 2015 ·Molecular Cell ·Brian J. Conti,Prasanna K. Devaraneni,Zhongying Yang,Larry L. David,William R. Skach	79
4	Endoplasmic Reticulum Protein Quality Control Is Determined by Cooperative Interactions between Hsp/c70 Protein and the CHIP E3 Ligase 2013 ·Journal of Biological Chemistry ·Yoshihiro Matsumura,Juro Sakai,William R. Skach	56
5	Mechanisms of CFTR Folding at the Endoplasmic Reticulum 2012 ·Frontiers in Pharmacology ·Soo Jung Kim,William R. Skach	88
6	Role of Hsc70 binding cycle in CFTR folding and endoplasmic reticulum–associated degradation 2011 ·Molecular Biology of the Cell ·Yoshihiro Matsumura,Larry L. David,William R. Skach	36
7	Stepwise Insertion and Inversion of a Type II Signal Anchor Sequence in the Ribosome-Sec61 Translocon Complex 2011 ·Cell ·Prasanna K. Devaraneni,Brian J. Conti,Yoshihiro Matsumura,Zhongying Yang,Arthur E. Johnson,William R. Skach	84
8	Cellular mechanisms of membrane protein folding 2009 ·Nature Structural & Molecular Biology ·William R. Skach	100
9	Sequence-specific Retention and Regulated Integration of a Nascent Membrane Protein by the Endoplasmic Reticulum Sec61 Translocon 2008 ·Molecular Biology of the Cell ·(unknown),Zhongying Yang,Yoshihiro Matsumura,Arthur E. Johnson,William R. Skach	45
10	Control of Translocation through the Sec61 Translocon by Nascent Polypeptide Structure within the Ribosome 2008 ·Journal of Biological Chemistry ·Colin J. Daniel,Brian J. Conti,Arthur E. Johnson,William R. Skach	31
11	Global Organization and Function of Mammalian Cytosolic Proteasome Pools: Implications for PA28 and 19S Regulatory Complexes 2006 ·Molecular Biology of the Cell ·(unknown),Eric J. Carlson,Fredrick J. Larabee,Ashley L. McCormack,Klaus Früh,William R. Skach	67
12	Aberrant Folding of a Mutant Stat5b Causes Growth Hormone Insensitivity and Proteasomal Dysfunction 2005 ·Journal of Biological Chemistry ·Dennis J. Chia,(unknown),Teresa M. Buck,Vivian Hwa,Ron G. Rosenfeld,William R. Skach,Ujwal Shinde,Peter Rotwein	24
13	Reticulocyte Lysate as a Model System to Study Endoplasmic Reticulum Membrane Protein Degradation 2005 ·Humana Press eBooks ·Eric J. Carlson,Nathan Bays,Larry L. David,William R. Skach	15
14	Sequential triage of transmembrane segments by Sec61α during biogenesis of a native multispanning membrane protein 2005 ·Nature Structural & Molecular Biology ·Heather Sadlish,(unknown),Arthur E. Johnson,William R. Skach	123
15	Evidence for stabilization of aquaporin-2 folding mutants by N-linked glycosylation in endoplasmic reticulum 2004 ·American Journal of Physiology-Cell Physiology ·Teresa M. Buck,(unknown),William R. Skach	42
16	Defects in processing and trafficking of the cystic fibrosis transmembrane conductance regulator 2000 ·Kidney International ·William R. Skach	78
17	Novel mutations in 13 probands with galactokinase deficiency 2000 ·Human Mutation ·Vladimir O. Kolosha,(unknown),Carlos de Céspedes,R Gitzelmann,(unknown),(unknown),(unknown),(unknown),Neil R.M. Buist,Thomas A. Tedesco,William R. Skach,(unknown),Dolena Ledee,Kristen Huang,Dwight Stambolian	31
18	Coupled Translocation Events Generate Topological Heterogeneity at the Endoplasmic Reticulum Membrane 1998 ·Molecular Biology of the Cell ·(unknown),(unknown),Yun Lu,Alvina Bragin,William R. Skach	33
19	Identification of a cDNA for Ca++-Independent Phospholipase A2 of Lung Lamellar Bodies/Lysosomes 1997 ·CHEST Journal ·Aron B. Fisher,Sheldon I. Feinstein,Tae‐Suk Kim,Chandra Dodia,William R. Skach	2
20	Distinct biogenesis mechanisms for the water channels MIWC and CHIP28 at the endoplasmic reticulum 1995 ·Biochemistry ·Lanbo Shi,William R. Skach,Tonghui Ma,A.S. Verkman	44

About William R. Skach

William R. Skach is a scholar working on Cell Biology, Molecular Biology and Pulmonary and Respiratory Medicine, having authored 87 papers that have together received 5.3k indexed citations. Recurring topics across this work include Cystic Fibrosis Research Advances (23 papers), RNA and protein synthesis mechanisms (22 papers) and Ion Transport and Channel Regulation (19 papers). The work is most often cited by research in Cell Biology (1.0k citations), Molecular Biology (3.9k citations) and Pulmonary and Respiratory Medicine (1.4k citations). William R. Skach has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include A.S. Verkman, Tonghui Ma, Hajime Hasegawa, Jeffrey L. Brodsky, Vishwanath R. Lingappa, Arthur E. Johnson, Zhongying Yang, Michael A. Matthay, Alfred N. Van Hoek and Antonio Frigeri. Their work appears in journals such as Science, Cell and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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