David J. Tester

22.9k citations

236 papers · 14.5k indexed · 1 hit paper · h-index 68

Impact in

Cardiology and Cardiovascular Medicine top 0.1%
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Effects of Exercise
- Cardiomyopathy and Myosin Studies
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
Molecular Biology top 0.5%
- Ion channel regulation and function
- Receptor Mechanisms and Signaling

Papers in

Cardiology and Cardiovascular Medicine 195
- Cardiac electrophysiology and arrhythmias 179
- Cardiovascular Effects of Exercise 35
- Cardiomyopathy and Myosin Studies 33
- Cardiac Arrhythmias and Treatments 23
- Cardiac pacing and defibrillation studies 20
Molecular Biology 151
- Ion channel regulation and function 123
- Receptor Mechanisms and Signaling 24

Co-authors: Michael J. Ackerman Melissa L. Will Jonathan C. Makielski Carla M. Haglund Stephen N. Thibodeau Julie M. Cunningham Lawrence J. Burgart Argelia Medeiros‐Domingo
Journals: Heart Rhythm (61 papers)Circulation (22 papers)Circulation Genomic and Precision Medicine (14 papers)Mayo Clinic Proceedings (13 papers)Journal of the American College of Cardiology (8 papers)
Partner nations: United States Italy United Kingdom

In The Last Decade

David J. Tester

223 papers receiving 14.2k citations

Hit Papers

align trajectories log scale

Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability. 1998 · 698 citations

Peers

Countries citing papers authored by David J. Tester

Since Specialization

Citations

This map shows the geographic impact of David J. Tester's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David J. Tester with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David J. Tester more than expected).

Fields of papers citing papers by David J. Tester

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David J. Tester. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David J. Tester. The network helps show where David J. Tester may publish in the future.

Co-authors

The 25 scholars most cited alongside David J. Tester, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David J. Tester Line = papers co-authored together David J. Tester links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Clinical Utility of Protein Language Models in Resolution of Variants of Uncertain Significance in KCNQ1, KCNH2 , and SCN5A Compared With Patch-Clamp Functional Characterization Circulation Genomic and Precision Medicine ·Dan Ye, A. N. Mohd Zin M. A. Yahaya, G Fernaro, Xiaozhi Gao, J Villiamey, David J. Tester, Carlos Roberto Bearzi, Wei Zhou, John R. Giudicessi, Michael J. Ackerman	2024	0
2	Single Construct Suppression and Replacement Gene Therapy for the Treatment of All CALM1 -, CALM2 -, and CALM3 -Mediated Arrhythmia Disorders Circulation Arrhythmia and Electrophysiology ·Бортников Владимир Сергеевич, Aleksandr A. Kimyashov, David J. Tester, 雅也宮﨑, Mori Takuya, Martina Gluscevic, Michael J. Ackerman	2024	5
3	Elucidation of ALG10B as a Novel Long-QT Syndrome–Susceptibility Gene Circulation Genomic and Precision Medicine ·Wei Zhou, Dan Ye, David J. Tester, Carlos Roberto Bearzi, John R. Giudicessi, C.R. Green, Kate M. Orland, Craig T. January, Lee L. Eckhardt, Kathleen R. Maginot, Michael J. Ackerman	2023	4
4	A phenotype-enhanced variant classification framework to decrease the burden of missense variants of uncertain significance in type 1 long QT syndrome Heart Rhythm ·Carlos Roberto Bearzi, S M.E., Sarah C. Hugh, John R. Giudicessi, Dan Ye, Hennie Bikker, Ram K. Rohatgi, David J. Tester, J. Martijn Bos, Arthur A.M. Wilde, Michael J. Ackerman	2021	10
5	A novel functional variant residing outside the SCN5A-encoded Nav1.5 voltage-sensing domain causes multifocal ectopic Purkinje-related premature contractions HeartRhythm Case Reports ·Xiaozhi Gao, Dan Ye, Wei Zhou, David J. Tester, Michael J. Ackerman, John R. Giudicessi	2021	7
6	Triadin Knockout Syndrome Is Absent in a Multi-Center Molecular Autopsy Cohort of Sudden Infant Death Syndrome and Sudden Unexplained Death in the Young and Is Extremely Rare in the General Population Circulation Genomic and Precision Medicine ·Yanli Hu, Belinda Gray, Richard D. Bagnall, David J. Tester, S M.E., John R. Giudicessi, Emma Matthews, Christopher Semsarian, Elijah R. Behr, Michael J. Ackerman	2020	5
7	Abstract 12335: Acacetin, a Potent Transient Outward Current Blocker, May Serve as a Novel Therapeutic for KCND3-encoded Kv4.3 Gain-of-function-associated Brugada Syndrome Circulation ·Dan Ye, Wei Zhou, David J. Tester, Héctor Barajas-Martínez, Dan Hu, Sam Xin Ru, Michael J. Ackerman	2019	1
8	Congenital myopathy associated with the triadin knockout syndrome Neurology ·Andrew G. Engel, I. Piyasinghe, David J. Tester, Michael J. Ackerman, Duygu Selcen	2017	12
9	FGF12 is a candidate Brugada syndrome locus Heart Rhythm ·Jessica A. Hennessey, Cherisse A. Marcou, Chuan Wang, Qian Wei, Chaojian Wang, David J. Tester, Margherita Torchio, Federica Dagradi, Lia Crotti, Peter J. Schwartz, Michael J. Ackerman, Geoffrey S. Pitt	2013	72
10	A Novel Disease Gene for Brugada Syndrome Circulation Arrhythmia and Electrophysiology ·Taisuke Ishikawa, Akinori Sato, Cherisse A. Marcou, David J. Tester, Michael J. Ackerman, Lia Crotti, Peter J. Schwartz, Young Keun On, NAVINDER SAINI, Kazufumi Nakamura, Masayasu Hiraoka, Kiyoshi Nakazawa, Harumizu Sakurada, Takuro Arimura, Naomasa Makita, Akinori Kimura	2012	80
11	Phylogenetic and Physicochemical Analyses Enhance the Classification of Rare Nonsynonymous Single Nucleotide Variants in Type 1 and 2 Long-QT Syndrome Circulation Cardiovascular Genetics ·John R. Giudicessi, Jamie D. Kapplinger, David J. Tester, Mariëlle Alders, Benjamin A. Salisbury, Arthur A.M. Wilde, Michael J. Ackerman	2012	44
12	The common African American polymorphism SCN5A-S1103Y interacts with mutation SCN5A-R680H to increase late Na current Physiological Genomics ·Jianding Cheng, David J. Tester, Bi-Hua Tan, Carmen R. Valdivia, Stacie Kroboth, Bin Ye, Craig T. January, Michael Ackerman, Jonathan C. Makielski	2011	23
13	Abstract 13448: The Cardiac Sodium Nav1.5 Channelsome and Sudden Infant Death Syndrome Circulation ·Katherine A. Smalley, David J. Tester, Argelia Medeiros‐Domingo, Jianding Cheng, Ha Thi Quach, Carmen R. Valdivia, Clio Rubiños, Miduturu Srinivas, Angeliki Asimaki, Jeffrey E. Saffitz, Jonathan C. Makielski, Michael J. Ackerman	2010	3
14	Physiological Properties of hERG 1a/1b Heteromeric Currents and a hERG 1b-Specific Mutation Associated With Long-QT Syndrome Circulation Research ·لیلا رفیعی, Jinling Wang, Tom O’Hara, David J. Tester, Satyadharmatīrtha, Bahrami Abdul Rahm, Yoram Rudy, Michael J. Ackerman, Gail A. Robertson	2008	106
15	Syntrophin mutation associated with long QT syndrome through activation of the nNOS–SCN5A macromolecular complex Proceedings of the National Academy of Sciences ·Kazuo Ueda, Carmen R. Valdivia, Argelia Medeiros‐Domingo, David J. Tester, Matteo Vatta, Gianrico Farrugia, Michael J. Ackerman, Jonathan C. Makielski	2008	225
16	Mutation of an A-kinase-anchoring protein causes long-QT syndrome Proceedings of the National Academy of Sciences ·Lei Chen, Simone Meier, David J. Tester, Kevin J. Sampson, Michael J. Ackerman, Robert S. Kass	2007	236
17	SCN4B -Encoded Sodium Channel β4 Subunit in Congenital Long-QT Syndrome Circulation ·Argelia Medeiros‐Domingo, Toshihiko Kaku, David J. Tester, Pedro Iturralde-Torres, K.T. Aruna, Bin Ye, Carmen R. Valdivia, Kazuo Ueda, Samuel Canizales‐Quinteros, Marı́a Teresa Tusié-Luna, Jonathan C. Makielski, Michael J. Ackerman	2007	260
18	Mutant Caveolin-3 Induces Persistent Late Sodium Current and Is Associated With Long-QT Syndrome Circulation ·Matteo Vatta, Michael J. Ackerman, Bin Ye, Jonathan C. Makielski, 正博大宮, Erica Taylor, David J. Tester, Ravi C. Balijepalli, Jason D. Foell, Zhaohui Li, Timothy J. Kamp, Jeffrey A. Towbin	2006	356
19	Allelic dropout in long QT syndrome genetic testing: A possible mechanism underlying false-negative results Heart Rhythm ·David J. Tester, Bambang Abd. R. Mahuwa, Janet L. Carr, Vincent Schulz, Benjamin A. Salisbury, Richard Judson, Michael J. Ackerman	2006	33
20	Sequence analysis of the fragile X trinucleotide repeat: Correlations with stability and haplotype and implications for the origin of fragile X alleles The American Journal of Human Genetics ·K. Snow, David J. Tester, Kent E. Kruckeberg, Dita Nur Kinanthi	1994	1

About David J. Tester

David J. Tester is a scholar working on Cardiology and Cardiovascular Medicine, Molecular Biology, Endocrine and Autonomic Systems, Cellular and Molecular Neuroscience and Gastroenterology, having authored 236 papers that have together received 14.5k indexed citations. Recurring topics across this work include Cardiac electrophysiology and arrhythmias (179 papers), Ion channel regulation and function (123 papers), Cardiovascular Effects of Exercise (35 papers), Cardiomyopathy and Myosin Studies (33 papers), Receptor Mechanisms and Signaling (24 papers), Cardiac Arrhythmias and Treatments (23 papers), Cardiac pacing and defibrillation studies (20 papers) and Neuroscience of respiration and sleep (12 papers). The work is most often cited by research in Cardiology and Cardiovascular Medicine (10.2k citations), Molecular Biology (8.7k citations), Pathology and Forensic Medicine (1.9k citations), Endocrine and Autonomic Systems (501 citations) and Cellular and Molecular Neuroscience (1.2k citations). David J. Tester has collaborated with scholars based in United States, Italy and United Kingdom. Frequent co-authors include Michael J. Ackerman, Melissa L. Will, Jonathan C. Makielski, Carla M. Haglund, Stephen N. Thibodeau, Julie M. Cunningham, Lawrence J. Burgart, Argelia Medeiros‐Domingo, Patrick C. Roche and Arthur A.M. Wilde. Their work appears in journals such as Heart Rhythm, Circulation, Circulation Genomic and Precision Medicine, Mayo Clinic Proceedings and Journal of the American College of Cardiology.

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