Darryl Shibata

21.4k citations

188 papers · 15.8k indexed · 6 hit papers · h-index 55

Impact in

Pathology and Forensic Medicine top 0.05%
- Genetic factors in colorectal cancer
- Lymphoma Diagnosis and Treatment
Cancer Research top 0.1%
- Cancer Genomics and Diagnostics

Papers in

Cancer Research 85
- Cancer Genomics and Diagnostics 82
Pathology and Forensic Medicine 95
- Genetic factors in colorectal cancer 72
- Lymphoma Diagnosis and Treatment 25

Co-authors: Manuel Perucho Norman Arnheim Miguel A. Peinado Sergei Malkhosyan Yurij Ionov Martin Wj Simon Tavaré Kathleen Forrester
Journals: Proceedings of the National Academy of Sciences (9 papers)Blood (8 papers)American Journal Of Pathology (8 papers)Cancer Research (5 papers)Carcinogenesis (5 papers)
Partner nations: United States United Kingdom Finland

In The Last Decade

Darryl Shibata

185 papers receiving 15.3k citations

Hit Papers

6 papers align trajectories log scale

A Big Bang model of human colorectal tumor growth 2015 · 666 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2015 Nature Genetics
2012 Science
1993 Nature
1992 Proceedings of the National Academy of Sciences
1988 Cell
1988 The Journal of Experimental Medicine

Peers

Countries citing papers authored by Darryl Shibata

Since Specialization

Citations

This map shows the geographic impact of Darryl Shibata's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Darryl Shibata with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Darryl Shibata more than expected).

Fields of papers citing papers by Darryl Shibata

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Darryl Shibata. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Darryl Shibata. The network helps show where Darryl Shibata may publish in the future.

Co-authors

The 25 scholars most cited alongside Darryl Shibata, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Darryl Shibata Line = papers co-authored together Darryl Shibata links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Fluctuating DNA methylation tracks cancer evolution at clinical scale Nature ·Calum Gabbutt, Martí Duran‐Ferrer, Heather E. Grant, Diego Mallo, Ferran Nadeu, Jacob Househam, Neus Villamor, Madlen Müller, Simon Heath, Emanuele Raineri, Olga Krali, Jessica Nordlund, Thorsten Zenz, (unknown), Elı́as Campo, Armando López‐Guillermo, Jude Fitzgibbon, C. Barnes, Darryl Shibata, José I. Martı́n-Subero, Trevor A. Graham	2025	2
2	Developmental hematopoietic stem cell variation explains clonal hematopoiesis later in life Nature Communications ·Jesse Kreger, Jazlyn A. Mooney, Darryl Shibata, Adam L. MacLean	2024	2
3	Gattaca: Base-Pair Resolution Mutation Tracking for Somatic Evolution Studies using Agent-based Models Molecular Biology and Evolution ·Ryan O. Schenck, Gabriel Brosula, Jeffrey West, Simon J. Leedham, Darryl Shibata, Alexander R.A. Anderson	2022	3
4	Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues Nature Biotechnology ·Calum Gabbutt, Ryan O. Schenck, Daniel J. Weisenberger, Christopher Kimberley, Alison Berner, Jacob Househam, Eszter Lakatos, Mark Robertson‐Tessi, Isabel Rodríguez Martín, Roshani Patel, Susan K. Clark, Andrew Latchford, C. Barnes, Simon J. Leedham, Alexander R.A. Anderson, Trevor A. Graham, Darryl Shibata	2022	27
5	Evolutionary Stem Cell Poker and Cancer Risks: the Paradox of the Large and Small Intestines Current Pathobiology Reports ·Darryl Shibata	2018	1
6	Single cell lineage tracing reveals a role for TgfβR2 in intestinal stem cell dynamics and differentiation Proceedings of the National Academy of Sciences ·Jared M. Fischer, Peter Calabrese, Ashleigh Miller, Nina M. Muñoz, William M. Grady, Darryl Shibata, R. Michael Liskay	2016	18
7	Induced pluripotent stem cell models of Zellweger spectrum disorder show impaired peroxisome assembly and cell type-specific lipid abnormalities Stem Cell Research & Therapy ·Xiao Ming Wang, Wing Yik, Peilin Zhang, Wange Lu, Ning Huang, Bo Ram Kim, Darryl Shibata, Madison Zitting, Robert H. Chow, Ann B. Moser, Steven J. Steinberg, Joseph G. Hacia	2015	11
8	Single-Molecule Genomic Data Delineate Patient-Specific Tumor Profiles and Cancer Stem Cell Organization Cancer Research ·Andrea Sottoriva, Inmaculada Spiteri, Darryl Shibata, Christina Curtis, Simon Tavaré	2012	50
9	Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer Science ·Antonija Kreso, Catherine O′Brien, Peter van Galen, Olga I. Gan, Faiyaz Notta, Andrew Brown, Karen Ng, Jing Ma, Erno Wienholds, Cyrille F. Dunant, Aaron Pollett, Steven Gallinger, John D. McPherson, Charles G. Mullighan, Darryl Shibata, John E. Dick Hit paper breakdown →	2012	557
10	Heterogeneity and Randomness of DNA Methylation Patterns in Human Embryonic Stem Cells DNA and Cell Biology ·Albert G. Tsai, Debbie M. Chen, Mayin Lin, John Hsieh, Cindy Yen Okitsu, Alexander Taghva, Darryl Shibata, Chih‐Lin Hsieh	2012	7
11	A simple algebraic cancer equation: calculating how cancers may arise with normal mutation rates BMC Cancer ·Peter Calabrese, Darryl Shibata	2010	44
12	Modeling DNA Methylation in a Population of Cancer Cells Statistical Applications in Genetics and Molecular Biology ·Kimberly D. Siegmund, Paul Marjoram, Darryl Shibata	2008	11
13	The Fuzzy Math of Solid Tumor Stem Cells: A Perspective Cancer Research ·Scott E. Kern, Darryl Shibata	2007	77
14	Stem Cell Chronicles: Autobiographies Within Genomes Stem Cell Reviews and Reports ·Darryl Shibata, Simon Tavaré	2007	6
15	Smad3 Deficiency Promotes Tumorigenesis in the Distal Colon of ApcMin/+ Mice Cancer Research ·Nicole M. Sodir, Xuan Chen, Ryan J. Park, Andrea E. Nickel, Peter S. Conti, Rex Moats, James R. Bading, Darryl Shibata, Peter W. Laird	2006	69
16	Counting Divisions in a Human Somatic Cell Tree: How, What and Why Cell Cycle ·Darryl Shibata, Simon Tavaré	2006	39
17	Generation and Characterization of Endonuclease G Null Mice Molecular and Cellular Biology ·Ryan A. Irvine, Noritaka Adachi, Darryl Shibata, Geoffrey D. Cassell, Kefei Yu, Zarir E. Karanjawala, Chih-Lin Hsieh, Michael R. Lieber	2004	83
18	Colorectal Adenoma and Cancer Divergence American Journal Of Pathology ·Jen‐Lan Tsao, Simon Tavaré, Reijo Salovaara, Jeremy R. Jass, Lauri A. Aaltonen, Darryl Shibata	1999	50
19	Nodal benign and malignant monocytoid B cells with and without follicular lymphomas: A comparative study of follicular colonization, light chain restriction, bcl-2, and t(14; 18) in 39 cases Human Pathology ·Antonio M. Hernández, Bharat N. Nathwani, Doyen Nguyen, Darryl Shibata, Wen Chuan, Peter W. Nichols, Clive R. Taylor	1995	18
20	Follicular Small Lymphocytic Lymphoma The American Journal of Surgical Pathology ·K L Chang, Daniel A. Arber, Darryl Shibata, Henry Rappaport, L. Weiss	1994	5

About Darryl Shibata

Darryl Shibata is a scholar working on Cancer Research, Pathology and Forensic Medicine, Oncology, Genetics and Molecular Biology, having authored 188 papers that have together received 15.8k indexed citations. Recurring topics across this work include Cancer Genomics and Diagnostics (82 papers), Genetic factors in colorectal cancer (72 papers), Epigenetics and DNA Methylation (35 papers), Viral-associated cancers and disorders (25 papers), Lymphoma Diagnosis and Treatment (25 papers), Colorectal Cancer Screening and Detection (14 papers), Colorectal Cancer Treatments and Studies (14 papers) and Cancer Cells and Metastasis (12 papers). The work is most often cited by research in Pathology and Forensic Medicine (6.6k citations), Cancer Research (4.8k citations), Oncology (7.4k citations), Molecular Biology (6.2k citations) and Genetics (1.8k citations). Darryl Shibata has collaborated with scholars based in United States, United Kingdom and Finland. Frequent co-authors include Manuel Perucho, Norman Arnheim, Miguel A. Peinado, Sergei Malkhosyan, Yurij Ionov, Martin Wj, Simon Tavaré, Kathleen Forrester, John J. Martin and Concepción Almoguera. Their work appears in journals such as Proceedings of the National Academy of Sciences, Blood, American Journal Of Pathology, Cancer Research and Carcinogenesis.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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