Chyi‐Ying A. Chen

5.0k citations

19 papers · 4.2k indexed · 1 hit paper · h-index 17

Molecular Biology top 2%
Cancer Research top 2%
Immunology top 5%
Oncology top 10%
Genetics top 10%

Co-authors: Ann‐Bin Shyu Nianhua Xu Nader Ezzeddine Nahum Sonenberg Christophe F. Grosset Hélène Jacquemin‐Sablon Jeffrey T. Chang Thomas R. Sundermeier
Topics: RNA Research and Splicing (18 papers)RNA and protein synthesis mechanisms (13 papers)RNA modifications and cancer (8 papers)
Cited by: Cancer Research Molecular Biology Immunology
Journals: Cell Nucleic Acids Research Molecular Cell
Partner nations: United States Canada Switzerland

In The Last Decade

Chyi‐Ying A. Chen

19 papers receiving 4.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

AU-rich elements: characterization and importance in mRNA degradation

1995 1.7k citations Chyi‐Ying A. Chen, Ann‐Bin Shyu Trends in Biochemical Sciences profile →

Peers

Countries citing papers authored by Chyi‐Ying A. Chen

Since Specialization

Citations

This map shows the geographic impact of Chyi‐Ying A. Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Chyi‐Ying A. Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Chyi‐Ying A. Chen more than expected).

Fields of papers citing papers by Chyi‐Ying A. Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Chyi‐Ying A. Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Chyi‐Ying A. Chen. The network helps show where Chyi‐Ying A. Chen may publish in the future.

Co-authorship network of co-authors of Chyi‐Ying A. Chen

This figure shows the co-authorship network connecting the top 25 collaborators of Chyi‐Ying A. Chen. A scholar is included among the top collaborators of Chyi‐Ying A. Chen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Chyi‐Ying A. Chen. Chyi‐Ying A. Chen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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19 of 19 papers shown

#	Work	Indexed citations
1	Antagonistic actions of two human Pan3 isoforms on global mRNA turnover 2017 ·RNA ·Chyi‐Ying A. Chen,Yueqiang Zhang,Yu Xiang,Leng Han,Ann‐Bin Shyu	12
2	MiR-26 down-regulates TNF-α/NF-κB signalling and IL-6 expression by silencing HMGA1 and MALT1 2016 ·Nucleic Acids Research ·Chyi‐Ying A. Chen,Jeffrey T. Chang,(unknown),Ann‐Bin Shyu	83
3	Emerging Themes in Regulation of Global mRNA Turnover in cis 2016 ·Trends in Biochemical Sciences ·Chyi‐Ying A. Chen,Ann‐Bin Shyu	33
4	Emerging mechanisms of mRNP remodeling regulation 2014 ·Wiley Interdisciplinary Reviews - RNA ·Chyi‐Ying A. Chen,Ann‐Bin Shyu	14
5	Mechanisms of deadenylation‐dependent decay 2010 ·Wiley Interdisciplinary Reviews - RNA ·Chyi‐Ying A. Chen,Ann‐Bin Shyu	234
6	Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation 2009 ·Molecular Cell ·Marc R. Fabian,Géraldine Mathonnet,Thomas R. Sundermeier,Hansruedi Mathys,(unknown),Yuri V. Svitkin,Fabiola V. Rivas,Martin Jínek,James A. Wohlschlegel,Jennifer A. Doudna,Chyi‐Ying A. Chen,Ann‐Bin Shyu,John R. Yates,Gregory J. Hannon,Witold Filipowicz,Thomas F. Duchaîne,Nahum Sonenberg	305
7	Chapter 17 Messenger RNA Half‐Life Measurements in Mammalian Cells 2008 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Chyi‐Ying A. Chen,Nader Ezzeddine,Ann‐Bin Shyu	199
8	Coordinated Changes in mRNA Turnover, Translation, and RNA Processing Bodies in Bronchial Epithelial Cells following Inflammatory Stimulation 2008 ·Molecular and Cellular Biology ·(unknown),Zhenping Zhong,Chyi‐Ying A. Chen,Zhenfang Xia,Song Ling,Michael R. Blackburn,Ann‐Bin Shyu	39
9	Functional dissection of hnRNP D suggests that nuclear import is required before hnRNP D can modulate mRNA turnover in the cytoplasm 2004 ·RNA ·Chyi‐Ying A. Chen,Nianhua Xu,Wenmiao Zhu,Ann‐Bin Shyu	28
10	Highly Selective Actions of HuR in Antagonizing AU-Rich Element-Mediated mRNA Destabilization 2002 ·Molecular and Cellular Biology ·Chyi‐Ying A. Chen,Nianhua Xu,Ann‐Bin Shyu	151
11	Versatile Role for hnRNP D Isoforms in the Differential Regulation of Cytoplasmic mRNA Turnover 2001 ·Molecular and Cellular Biology ·Nianhua Xu,Chyi‐Ying A. Chen,Ann‐Bin Shyu	154
12	A Mechanism for Translationally Coupled mRNA Turnover 2000 ·Cell ·Christophe F. Grosset,Chyi‐Ying A. Chen,Nianhua Xu,Nahum Sonenberg,Hélène Jacquemin‐Sablon,Ann‐Bin Shyu	263
13	Transcriptional Pulsing Approaches for Analysis of mRNA Turnover in Mammalian Cells 1999 ·Methods ·Paul T. Loflin,Chyi‐Ying A. Chen,Nianhua Xu,Ann‐Bin Shyu	66
14	Modulation of the Fate of Cytoplasmic mRNA by AU-Rich Elements: Key Sequence Features Controlling mRNA Deadenylation and Decay 1997 ·Molecular and Cellular Biology ·Nianhua Xu,Chyi‐Ying A. Chen,Ann‐Bin Shyu	313
15	Functional Characterization of a Non-AUUUA AU-Rich Element from the c-jun Proto-Oncogene mRNA: Evidence for a Novel Class of AU-Rich Elements 1996 ·Molecular and Cellular Biology ·(unknown),Chyi‐Ying A. Chen,Ann‐Bin Shyu	126
16	mRNA Decay Mediated by Two Distinct AU-Rich Elements from c- fos and Granulocyte-Macrophage Colony-Stimulating Factor Transcripts: Different Deadenylation Kinetics and Uncoupling from Translation 1995 ·Molecular and Cellular Biology ·Chyi‐Ying A. Chen,Nianhua Xu,Ann‐Bin Shyu	251
17	AU-rich elements: characterization and importance in mRNA degradationbreakdown → 1995 ·Trends in Biochemical Sciences ·Chyi‐Ying A. Chen,Ann‐Bin Shyu	1682
18	Selective Degradation of Early-Response-Gene mRNAs: Functional Analyses of Sequence Features of the AU-Rich Elements 1994 ·Molecular and Cellular Biology ·Chyi‐Ying A. Chen,Ann‐Bin Shyu	225
19	Two Cellular Proteins Bind Specifically to a Purine-Rich Sequence Necessary for the Destabilization Function of a c-fos Protein-Coding Region Determinant of mRNA Instability 1992 ·Molecular and Cellular Biology ·Chyi‐Ying A. Chen,Yun You,Ann‐Bin Shyu	24

About Chyi‐Ying A. Chen

Chyi‐Ying A. Chen is a scholar working on Molecular Biology, Cancer Research and Cardiology and Cardiovascular Medicine, having authored 19 papers that have together received 4.2k indexed citations. Recurring topics across this work include RNA Research and Splicing (18 papers), RNA and protein synthesis mechanisms (13 papers) and RNA modifications and cancer (8 papers). The work is most often cited by research in Cancer Research (775 citations), Molecular Biology (3.5k citations) and Immunology (533 citations). Chyi‐Ying A. Chen has collaborated with scholars based in United States, Canada and Switzerland. Frequent co-authors include Ann‐Bin Shyu, Nianhua Xu, Nader Ezzeddine, Nahum Sonenberg, Christophe F. Grosset, Hélène Jacquemin‐Sablon, Jeffrey T. Chang, Thomas R. Sundermeier, Martin Jínek and Thomas F. Duchaîne. Their work appears in journals such as Cell, Nucleic Acids Research and Molecular Cell.

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