Christopher Hulme

6.3k citations

125 papers · 5.1k indexed · 1 hit paper · h-index 39

Impact in

Organic Chemistry top 0.2%
- Multicomponent Synthesis of Heterocycles
- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Catalytic C–H Functionalization Methods
- Synthetic Organic Chemistry Methods
- Click Chemistry and Applications
Pharmacology top 1%
- Synthesis of Organic Compounds

Papers in

Organic Chemistry 96
- Multicomponent Synthesis of Heterocycles 61
- Synthesis and Biological Evaluation 22
- Synthesis and biological activity 21
- Synthetic Organic Chemistry Methods 17
- Quinazolinone synthesis and applications 10
- Click Chemistry and Applications 9
Molecular Biology 66
- Chemical Synthesis and Analysis 51

Co-authors: Vijay Gore Justin Dietrich Arthur Y. Shaw Zhigang Xu Richard Labaudinière Fabio De Moliner Thomas Nixey Federico Medda
Journals: Tetrahedron Letters (41 papers)Bioorganic & Medicinal Chemistry Letters (8 papers)Organic Letters (8 papers)Molecular Diversity (6 papers)The Journal of Organic Chemistry (4 papers)
Partner nations: United States United Kingdom Taiwan

In The Last Decade

Christopher Hulme

124 papers receiving 4.9k citations

Hit Papers

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“Multi-component Reactions : Emerging Chemistry in Drug Discovery” ‘From Xylocain to Crixivan’ 2003 · 942 citations

Peers

Countries citing papers authored by Christopher Hulme

Since Specialization

Citations

This map shows the geographic impact of Christopher Hulme's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher Hulme with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher Hulme more than expected).

Fields of papers citing papers by Christopher Hulme

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher Hulme. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher Hulme. The network helps show where Christopher Hulme may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Christopher Hulme, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Christopher Hulme Line = papers co-authored together Christopher Hulme links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Synthesis of Copper–Nickel and Iron–Nickel Alloys by Hydrogen Reduction of Mixtures of Metal Oxide Powders Journal of Sustainable Metallurgy ·Danielle Nemcovsky‐Amar, Pelle Mellin, Christopher Hulme	2024	0
2	Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B Journal of Medicinal Chemistry ·Vladimir Vadimovich Eremuk, Hassan Alshamrani, Anucha Sangrung, Christopher Foley, Mandou Mouncharou Marie Solange, Breland E. Smith, Alice D. Welcher, J. G. Wang, Aaron Babendreyer, Luca Giacobazzi, نوف العنزي, Vijay Gokhale, Sebastian Kallabis, Felix Meissner, Boingotlo Masake, Travis Dunckley, W.R. Montfort, Walter Becker, Christopher Hulme	2024	6
3	Deuterated reagents in multicomponent reactions to afford deuterium-labeled products Beilstein Journal of Organic Chemistry ·Hassan Alshamrani, Anucha Sangrung, Yueteng Zhang, C. Sebening, Wang Ziyuan, Wei Wang, James J. Galligan, Christopher Hulme	2024	1
4	The full spectrum tuning of fluorescent molecules via a one-pot multicomponent reaction Tetrahedron Letters ·鼻輪康雄, Michelle Robin Alber, Cecilia Mir, 慶太秋元, Kurnia Suci Ramadhani, Luca Giacobazzi, Dennis L. Lichtenberger, Christopher Hulme	2023	2
5	Crystal structures ofN-tert-butyl-3-(4-fluorophenyl)-5-oxo-4-[2-(trifluoromethoxy)phenyl]-2,5-dihydrofuran-2-carboxamide and 4-(2H-1,3-benzodioxol-5-yl)-N-cyclohexyl-5-oxo-3-[4-(trifluoromethyl)phenyl]-2,5-dihydrofuran-2-carboxamide SHILAP Revista de lepidopterología ·Sue A. Roberts, Noboru Horibe, Christopher Hulme	2015	1
6	Exploiting the divalent nature of isonitriles: a novel Pictet–Spengler amidination process Tetrahedron Letters ·Federico Medda, Christopher Hulme	2014	17
7	MCRs reshaped into a switchable microwave-assisted protocol toward 5-aminoimidazoles and dihydrotriazines Tetrahedron ·礼子梅田, Arthur Y. Shaw, Fabio De Moliner, Christopher Hulme	2013	26
8	Ugi/Aldol Sequence: Expeditious Entry to Several Families of Densely Substituted Nitrogen Heterocycles Angewandte Chemie International Edition ·Zhigang Xu, Fabio De Moliner, Yukikazu Ito, Christopher Hulme	2012	83
9	Synthesis of tetrazolo-fused benzodiazepines and benzodiazepinones by a two-step protocol using an Ugi-azide reaction for initial diversity generation Tetrahedron ·Steven Gunawan, Muhammad Ayaz, Fabio De Moliner, Brendan Frett, Christine Kaiser, S. Kuś, Zhigang Xu, Christopher Hulme	2012	38
10	Synthesis and biological activity of aminophthalazines and aminopyridazines as novel inhibitors of PGE2 production in cells Bioorganic & Medicinal Chemistry Letters ·Federico Medda, Maria Fabrizia Buongiorno, Hui Hua Chang, Justin Dietrich, Jawad , Breland E. Smith, Vijay Gokhale, Emmanuelle J. Meuillet, Christopher Hulme	2012	11
11	Two-step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines Tetrahedron Letters ·Zhigang Xu, Justin Dietrich, Arthur Y. Shaw, Christopher Hulme	2010	19
12	The design, synthesis, and evaluation of 8 hybrid DFG-out allosteric kinase inhibitors: A structural analysis of the binding interactions of Gleevec®, Nexavar®, and BIRB-796 Bioorganic & Medicinal Chemistry ·Justin Dietrich, Christopher Hulme, Laurence H. Hurley	2010	165
13	Health Outcome Measures in the Evaluation of Total Hip Arthroplasties—A Comparison Between the Harris Hip Score and the Oxford Hip Score The Journal of Arthroplasty ·Yegappan Kalairajah, Ivana Hovorková, Christopher Hulme, Sean Molloy, K J Drabu	2005	185
14	Library Generation via Postcondensation Modifications of Isocyanide-Based Multicomponent Reactions Methods in enzymology on CD-ROM/Methods in enzymology ·Christopher Hulme, Hugues Bienaymé, Thomas Nixey, Balan Chenera, Michael Q. Bailey, Paul Tempest, Adrian L. Smith	2003	35
15	“Multi-component Reactions : Emerging Chemistry in Drug Discovery” ‘From Xylocain to Crixivan’ Current Medicinal Chemistry ·Christopher Hulme, Vijay Gore Hit paper breakdown →	2003	942
16	One-pot microwave assisted preparation of pyrazoloquinazolinone libraries Molecular Diversity ·Manjit Sultan, Thomas Nixey, Balan Chenera, Vijay Gore, Michael D. Bartberger, Yaxiong Sun, Christopher Hulme	2003	11
17	The synthesis and biological evaluation of a novel series of indole PDE4 inhibitors I Bioorganic & Medicinal Chemistry Letters ·Christopher Hulme, K.J.M. Moriarty, Bruce E. Miller, Rose Mathew, C. X. Yu, Paul Alan Cox, John E. Souness, Ken Page, Joanne Uhl, Jun Zhuang, Dzh Dzholi, Richard Labaudinière, Stevan W. Djurić	1998	15
18	Orally active indole N-oxide PDE4 inhibitors Bioorganic & Medicinal Chemistry Letters ·Christopher Hulme, Rose Mathew, K.J.M. Moriarty, Bruce E. Miller, C. X. Yu, Paul Alan Cox, John E. Souness, Ken Page, Joanne Uhl, Jun Zhuang, Richard Labaudinière, Dzh Dzholi, Stevan W. Djurić	1998	9
19	Quaternary substituted PDE IV inhibitors II: The synthesis and in vitro evaluation of a novel series of γ-lactams Bioorganic & Medicinal Chemistry Letters ·Christopher Hulme, K.J.M. Moriarty, Fu‐Chih Huang, J. Anaya, Roberto Demidchuk, Richard Labaudinière, John E. Souness, Stevan W. Djurić	1998	9
20	Novel 2- and 5-Azido-N-(diphenylcarbamoyl)proline Methyl Esters. Examples of a Novel Proline Oxidation Acta Crystallographica Section C Crystal Structure Communications ·Vincent M. Lynch, Christopher Hulme, Philip Magnus, Mandar Mainkar	1995	1

About Christopher Hulme

Christopher Hulme is a scholar working on Organic Chemistry, Molecular Biology, Pharmacology, Pharmaceutical Science and Toxicology, having authored 125 papers that have together received 5.1k indexed citations. Recurring topics across this work include Multicomponent Synthesis of Heterocycles (61 papers), Chemical Synthesis and Analysis (51 papers), Synthesis and Biological Evaluation (22 papers), Synthesis and biological activity (21 papers), Synthetic Organic Chemistry Methods (17 papers), Quinazolinone synthesis and applications (10 papers), Click Chemistry and Applications (9 papers) and Synthesis of Organic Compounds (9 papers). The work is most often cited by research in Organic Chemistry (4.0k citations), Pharmacology (596 citations), Toxicology (108 citations), Molecular Biology (2.0k citations) and Computational Theory and Mathematics (313 citations). Christopher Hulme has collaborated with scholars based in United States, United Kingdom and Taiwan. Frequent co-authors include Vijay Gore, Justin Dietrich, Arthur Y. Shaw, Zhigang Xu, Richard Labaudinière, Fabio De Moliner, Thomas Nixey, Federico Medda, Philip Magnus and Isabelle Morize. Their work appears in journals such as Tetrahedron Letters, Bioorganic & Medicinal Chemistry Letters, Organic Letters, Molecular Diversity and The Journal of Organic Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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