John E. Souness

1.6k total citations
27 papers, 1.2k citations indexed

About

John E. Souness is a scholar working on Molecular Biology, Physiology and Organic Chemistry. According to data from OpenAlex, John E. Souness has authored 27 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 9 papers in Physiology and 7 papers in Organic Chemistry. Recurrent topics in John E. Souness's work include Phosphodiesterase function and regulation (20 papers), Phenothiazines and Benzothiazines Synthesis and Activities (6 papers) and Asthma and respiratory diseases (6 papers). John E. Souness is often cited by papers focused on Phosphodiesterase function and regulation (20 papers), Phenothiazines and Benzothiazines Synthesis and Activities (6 papers) and Asthma and respiratory diseases (6 papers). John E. Souness collaborates with scholars based in United States, United Kingdom and Mexico. John E. Souness's co-authors include S. R. Rao, Carol A. Sargent, David Aldous, Malcolm N. Palfreyman, Jan‐Anders Karlsson, Lorna Wood, Nicholas C. Turner, Adrian Tomkinson, Roy Jordan and David Raeburn and has published in prestigious journals such as FEBS Letters, Journal of Medicinal Chemistry and British Journal of Pharmacology.

In The Last Decade

John E. Souness

27 papers receiving 1.1k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
John E. Souness United States 17 919 400 316 280 227 27 1.2k
Miriam Burman United States 17 812 0.9× 299 0.7× 295 0.9× 211 0.8× 239 1.1× 28 1.1k
Laura Lucarini Italy 22 649 0.7× 153 0.4× 133 0.4× 281 1.0× 116 0.5× 55 1.2k
Peppi Prasit United States 21 592 0.6× 234 0.6× 189 0.6× 242 0.9× 120 0.5× 44 1.2k
Iain G. Dougall United Kingdom 17 528 0.6× 235 0.6× 118 0.4× 98 0.3× 84 0.4× 29 939
Marie‐Claude Carrière Canada 13 275 0.3× 210 0.5× 407 1.3× 215 0.8× 55 0.2× 14 927
Robert W. Bonser United Kingdom 17 697 0.8× 274 0.7× 106 0.3× 58 0.2× 284 1.3× 28 1.1k
Ralph Mosley United States 12 698 0.8× 218 0.5× 183 0.6× 172 0.6× 58 0.3× 15 1.2k
N.H. Wilson United Kingdom 17 422 0.5× 311 0.8× 595 1.9× 119 0.4× 111 0.5× 34 1.2k
Hélène Jûteau Canada 13 346 0.4× 188 0.5× 522 1.7× 654 2.3× 44 0.2× 22 1.4k
Steven Hockman United States 15 761 0.8× 176 0.4× 159 0.5× 60 0.2× 82 0.4× 23 1.0k

Countries citing papers authored by John E. Souness

Since Specialization
Citations

This map shows the geographic impact of John E. Souness's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John E. Souness with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John E. Souness more than expected).

Fields of papers citing papers by John E. Souness

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John E. Souness. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John E. Souness. The network helps show where John E. Souness may publish in the future.

Co-authorship network of co-authors of John E. Souness

This figure shows the co-authorship network connecting the top 25 collaborators of John E. Souness. A scholar is included among the top collaborators of John E. Souness based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John E. Souness. John E. Souness is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Collis, Alan, Martyn Foster, Frank Halley, et al.. (2001). RPR203494 a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency. Bioorganic & Medicinal Chemistry Letters. 11(5). 693–696. 33 indexed citations
2.
Souness, John E., David Aldous, & Carol A. Sargent. (2000). Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors. Immunopharmacology. 47(2-3). 127–162. 205 indexed citations
3.
4.
Hulme, Christopher, K.J.M. Moriarty, Bruce E. Miller, et al.. (1998). The synthesis and biological evaluation of a novel series of indole PDE4 inhibitors I. Bioorganic & Medicinal Chemistry Letters. 8(14). 1867–1872. 15 indexed citations
5.
Hulme, Christopher, Rose Mathew, K.J.M. Moriarty, et al.. (1998). Orally active indole N-oxide PDE4 inhibitors. Bioorganic & Medicinal Chemistry Letters. 8(21). 3053–3058. 9 indexed citations
6.
Hulme, Christopher, K.J.M. Moriarty, Fu‐Chih Huang, et al.. (1998). Quaternary substituted PDE IV inhibitors II: The synthesis and in vitro evaluation of a novel series of γ-lactams. Bioorganic & Medicinal Chemistry Letters. 8(4). 399–404. 9 indexed citations
7.
Regan, John R., Joseph G. Bruno, Daniel McGarry, et al.. (1998). 2-Substituted-4-methoxybenzimidazole-based PDE4 inhibitors. Bioorganic & Medicinal Chemistry Letters. 8(19). 2737–2742. 8 indexed citations
8.
Souness, John E. & S. R. Rao. (1997). Proposal for Pharmacologically Distinct Conformers of PDE4 Cyclic AMP Phosphodiesterases. Cellular Signalling. 9(3-4). 227–236. 149 indexed citations
9.
10.
Souness, John E., Miriam Griffin, Karen Ebsworth, et al.. (1996). Evidence that cyclic AMP phosphodiesterase inhibitors suppress TNFα generation from human monocytes by interacting with a ‘low‐affinity’ phosphodiesterase 4 conformer. British Journal of Pharmacology. 118(3). 649–658. 104 indexed citations
11.
12.
Raeburn, David, Stephen L. Underwood, S.A. Lewis, et al.. (1994). Anti‐inflammatory and bronchodilator properties of RP 73401, a novel and selective phosphodiesterase type IV inhibitor. British Journal of Pharmacology. 113(4). 1423–1431. 83 indexed citations
13.
Souness, John E., et al.. (1994). Possible role of cyclic AMP phosphodiesterases in the actions of ibudilast on eosinophil thromboxane generation and airways smooth muscle tone. British Journal of Pharmacology. 111(4). 1081–1088. 45 indexed citations
14.
Raeburn, David, John E. Souness, Adrian Tomkinson, & Jan‐Anders Karlsson. (1993). Isozyme-selective cyclic nucleotide phosphodiesterase inhibitors: Biochemistry, pharmacology and therapeutic potential in asthma. Birkhäuser Basel eBooks. 40. 9–32. 34 indexed citations
15.
Turner, Nicholas C., et al.. (1993). The effect of cyclic AMP and cyclic GMP phosphodiesterase inhibitors on the superoxide burst of guinea‐pig peritoneal macrophages. British Journal of Pharmacology. 108(4). 876–883. 57 indexed citations
16.
Souness, John E., et al.. (1992). Inhibition of pig aortic smooth muscle cell DNA synthesis by selective type III and type IV cyclic AMP phosphodiesterase inhibitors. Biochemical Pharmacology. 44(5). 857–866. 68 indexed citations
17.
18.
Souness, John E., et al.. (1991). Characterization of guinea-pig eosinophil phosphodiesterase activity. Biochemical Pharmacology. 42(4). 937–945. 90 indexed citations
19.
20.
Souness, John E., et al.. (1987). Characterization of 5′-N ethylcarboxamido[3H]adenosine binding to pig aorta smooth muscle membranes. Biochemical Pharmacology. 36(21). 3621–3627. 13 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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