Christopher Bebbington

2.1k citations

35 papers · 1.7k indexed · h-index 20

Impact in

Immunology top 5%
- Immune Cell Function and Interaction
- Mast cells and histamine
- Immunotherapy and Immune Responses
Immunology and Allergy top 5%

Papers in

Immunology and Allergy 5
Immunology 13
- Mast cells and histamine 9

Co-authors: Helene M. Finney A. Neil C. Weir Alastair D. G. Lawson Geoffrey Yarranton Nenad Tomas̆ević John Leung Rustom Falahati Mark Baer
Journals: Blood (10 papers)Journal of Allergy and Clinical Immunology (4 papers)Gastroenterology (2 papers)Human Molecular Genetics (1 paper)International Archives of Allergy and Immunology (1 paper)
Partner nations: United States Australia Italy

In The Last Decade

Christopher Bebbington

33 papers receiving 1.6k citations

Peers

Countries citing papers authored by Christopher Bebbington

Since Specialization

Citations

This map shows the geographic impact of Christopher Bebbington's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher Bebbington with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher Bebbington more than expected).

Fields of papers citing papers by Christopher Bebbington

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher Bebbington. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher Bebbington. The network helps show where Christopher Bebbington may publish in the future.

Co-authors

The 25 scholars most cited alongside Christopher Bebbington, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Christopher Bebbington Line = papers co-authored together Christopher Bebbington links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Discovery, Function, and Therapeutic Targeting of Siglec-8 Cells ·Bradford A. Youngblood, John Leung, Rustom Falahati, J.C. Williams, Julia Schanin, Emily C. Brock, Bhupinder Singh, Alan T. Chang, Jeremy A. O’Sullivan, Robert P. Schleimer, Nenad Tomas̆ević, Christopher Bebbington, Bruce S. Bochner	2020	62
2	A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation Mucosal Immunology ·Julia Schanin, Simon Gebremeskel, Wouter Korver, Rustom Falahati, M. A. Iliescu, Tatt Jhong Haw, Prema M. Nair, Gang Liu, Nicole G. Hansbro, Philip M. Hansbro, Dinara Kasradze, Emily C. Brock, Alan Xu, Richard G. Doty, John Leung, Christopher Bebbington, Nenad Tomas̆ević, Bradford A. Youngblood	2020	60
3	AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice International Archives of Allergy and Immunology ·Bradford A. Youngblood, Emily C. Brock, John Leung, Rustom Falahati, Paul Bryce, Jessica Bright, J.C. Williams, Leonard D. Shultz, Dale L. Greiner, Michael A. Brehm, Christopher Bebbington, Nenad Tomas̆ević	2019	84
4	Siglec-8 antibody reduces eosinophils and mast cells in a transgenic mouse model of eosinophilic gastroenteritis JCI Insight ·Bradford A. Youngblood, Emily C. Brock, John Leung, Rustom Falahati, Bruce S. Bochner, Henrik Rasmussen, Kathryn A. Peterson, Christopher Bebbington, Nenad Tomas̆ević	2019	79
5	Sialic acid–binding immunoglobulin-like lectin (Siglec) 8 in patients with eosinophilic disorders: Receptor expression and targeting using chimeric antibodies Journal of Allergy and Clinical Immunology ·Fanny Legrand, Yun Cao, Joshua B. Wechsler, Xiang Zhu, Nives Zimmermann, Shakuntala Rampertaap, 吉男小南, Kyungmee Gug, Bradford A. Youngblood, Emily C. Brock, Michelle Makiya, Nenad Tomas̆ević, Christopher Bebbington, Irina Marić, Dean D. Metcalfe, Bruce S. Bochner, Amy D. Klion	2018	45
6	352 - AK002, a First-in-Class, Humanized, Non-Fucosylated IGG1 Siglec-8 Antibody, Selectively Depletes Blood and Tissue Eosinophils Gastroenterology ·Bradford A. Youngblood, Emily C. Brock, John Leung, Christopher Bebbington, Nenad Tomas̆ević	2018	1
7	Humanized mouse model of mast cell–mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis Journal of Allergy and Clinical Immunology ·Paul Bryce, Rustom Falahati, Laurie L. Kenney, John Leung, Christopher Bebbington, Nenad Tomas̆ević, Rebecca A. Krier-Burris, Chia‐Lin Hsu, Leonard D. Shultz, Dale L. Greiner, Michael A. Brehm	2016	82
8	Targeting EphA3 Inhibits Cancer Growth by Disrupting the Tumor Stromal Microenvironment Cancer Research ·Mary E. Vail, Carmel Murone, Veronika Chvátalová, Linda Hii, Jennifer Berglund, Peter W. Janes, Fook-Thean Lee, Mark Baer, P Sanwaria, Christopher Bebbington, Geoffrey Yarranton, A. J. Cuerda, I. G. Vilesova, David Abramson, Glenn A. Cartwright, Andrew M. Scott, Martin Lackmann	2014	67
9	A high affinity recombinant antibody to the human EphA3 receptor with enhanced ADCC activity Growth Factors ·Nenad Tomas̆ević, Kenneth R. Luehrsen, Mark Baer, P Sanwaria, David Martínez, J.C. Williams, Johanna Virstedt, Swathi Sujatha-Bhaskar, 河村洋行, John Leung, شریف حمدی, Vladimir Shaydakov, Elsisabeth Siti Herini, Geoffrey Yarranton, Christopher Bebbington	2014	10
10	The eosinophil surface receptor epidermal growth factor–like module containing mucin-like hormone receptor 1 (EMR1): A novel therapeutic target for eosinophilic disorders Journal of Allergy and Clinical Immunology ·Fanny Legrand, Nenad Tomas̆ević, Olga Šimáková, Chyi‐Chia Richard Lee, Δέσποινα Χριστοπούλου, Mark Raffeld, Michelle Makiya, P Sanwaria, John Leung, Mark Baer, Geoffrey Yarranton, Irina Marić, Christopher Bebbington, Amy D. Klion	2014	52
11	GM-CSF–dependent pSTAT5 sensitivity is a feature with therapeutic potential in chronic myelomonocytic leukemia Blood ·Eric Padron, Jeffrey S. Painter, Sateesh Kunigal, Adam W. Mailloux, Kathy L. McGraw, F Leibundgut, Eun Hee Kim, Christopher Bebbington, Mark Baer, Geoffrey Yarranton, Jeffrey E. Lancet, Rami S. Komrokji, Omar Abdel‐Wahab, Alan F. List, Pearlie K. Epling‐Burnette	2013	108
12	Antibody to Granulocyte Macrophage Colony–stimulating Factor Reduces the Number of Activated Tissue Macrophages and Improves Left Ventricular Function After Myocardial Infarction in a Rat Coronary Artery Ligation Model Journal of Cardiovascular Pharmacology ·Robert S. Kellar, 瀧波慶和, Jiacheng Yao, Elizabeth Juneman, Nicholle M. Johnson, Robin Stokke Johansen, Maribeth Stansifer, Reza Arsanjani, Mark Baer, Christopher Bebbington, Michael Flashner, Geoffrey Yarranton, Steven Goldman	2011	10
13	GM-CSF Signaling Abnormalities in Chronic Myelomonocytic Leukemia Blood ·Eric Padron, Jeffrey S. Painter, Adam W. Mailloux, F Leibundgut, Christopher Bebbington, Mark Baer, Rami S. Komrokji, Alan F. List, Pearlie K. Epling‐Burnette	2011	2
14	Neutralization of granulocyte macrophage colony-stimulating factor decreases amyloid beta 1-42 and suppresses microglial activity in a transgenic mouse model of Alzheimer's disease Human Molecular Genetics ·Maria Mańczak, Peizhong Mao, Kazuhiro Nakamura, Christopher Bebbington, Byung Park, P. Hemachandra Reddy	2009	46
15	Granulocyte‐macrophage colony‐stimulating factor antibody suppresses microglial activity: implications for anti‐inflammatory effects in Alzheimer’s Disease and multiple sclerosis Journal of Neurochemistry ·P. Hemachandra Reddy, Maria Mańczak, Wei Zhao, Kazuhiro Nakamura, Christopher Bebbington, Geoffrey Yarranton, Peizhong Mao	2009	26
16	Antibodies for the treatment of bacterial infections: current experience and future prospects Current Opinion in Biotechnology ·Christopher Bebbington, Geoffrey Yarranton	2008	75
17	The Receptor for Type I IFNs Is Highly Expressed on Peripheral Blood B Cells and Monocytes and Mediates a Distinct Profile of Differentiation and Activation of These Cells Journal of Interferon & Cytokine Research ·Sarah Pogue, Chung Cheng Han, Chie Nakaniwa, Christopher Bebbington, Pina M. Cardarelli	2004	52
18	The use of UCOE vectors in combination with a preadapted serum free, suspension cell line allows for rapid production of large quantities of protein Cytotechnology ·Beata Kanarek, Timothy F. Chen, Enno Putri Liana, Brian A. Fox, David King, Robert Crombie, Thomas C. Thomas, Christopher Bebbington	2002	75
19	Chimeric Receptors Providing Both Primary and Costimulatory Signaling in T Cells from a Single Gene Product The Journal of Immunology ·Helene M. Finney, Alastair D. G. Lawson, Christopher Bebbington, A. Neil C. Weir	1998	432
20	The use of engineered E1A genes to transactivate the hCMV-MIE promoter in permanent CHO cell lines Nucleic Acids Research ·Mark I. Cockett, Christopher Bebbington, Geoffrey Yarranton	1991	56

About Christopher Bebbington

Christopher Bebbington is a scholar working on Immunology and Allergy, Immunology, Rheumatology, Endocrinology and Radiology, Nuclear Medicine and Imaging, having authored 35 papers that have together received 1.7k indexed citations. Recurring topics across this work include Mast cells and histamine (9 papers), Monoclonal and Polyclonal Antibodies Research (7 papers), Eosinophilic Disorders and Syndromes (6 papers), Eosinophilic Esophagitis (5 papers), Asthma and respiratory diseases (5 papers), Viral Infectious Diseases and Gene Expression in Insects (4 papers), Axon Guidance and Neuronal Signaling (4 papers) and Acute Myeloid Leukemia Research (3 papers). The work is most often cited by research in Immunology (618 citations), Immunology and Allergy (154 citations), Oncology (551 citations), Rheumatology (206 citations) and Molecular Medicine (67 citations). Christopher Bebbington has collaborated with scholars based in United States, Australia and Italy. Frequent co-authors include Helene M. Finney, A. Neil C. Weir, Alastair D. G. Lawson, Geoffrey Yarranton, Nenad Tomas̆ević, John Leung, Rustom Falahati, Mark Baer, Emily C. Brock and Bradford A. Youngblood. Their work appears in journals such as Blood, Journal of Allergy and Clinical Immunology, Gastroenterology, Human Molecular Genetics and International Archives of Allergy and Immunology.

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