Christine Burlein

1.3k citations

18 papers · 449 indexed · h-index 11

Co-authors: Steven S. Carroll David B. Olsen Michele Bosserman Daniel R. McMasters Shi‐Shan Mao Malcolm MacCoss Marija Prhavc Joanne E. Tomassini
Topics: HIV/AIDS drug development and treatment (12 papers)HIV Research and Treatment (6 papers)Click Chemistry and Applications (5 papers)
Cited by: Hepatology Virology Infectious Diseases
Journals: Nature Communications Analytical Biochemistry Journal of Medicinal Chemistry
Partner nations: United States Canada

In The Last Decade

Christine Burlein

18 papers receiving 429 citations

Peers

Countries citing papers authored by Christine Burlein

Since Specialization

Citations

This map shows the geographic impact of Christine Burlein's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christine Burlein with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christine Burlein more than expected).

Fields of papers citing papers by Christine Burlein

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christine Burlein. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christine Burlein. The network helps show where Christine Burlein may publish in the future.

Co-authorship network of co-authors of Christine Burlein

This figure shows the co-authorship network connecting the top 25 collaborators of Christine Burlein. A scholar is included among the top collaborators of Christine Burlein based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christine Burlein. Christine Burlein is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

#	Work	Indexed citations
1	Discovery of arylsulfonamides as a novel class of allosteric integrase inhibitors with antiviral activity 2023 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Gregory C. Adam,Christine Burlein,Steven S. Carroll,(unknown),Tracy L. Diamond,Jay A. Grobler,(unknown),Adam Johnson,Daniel J. Klein,Daniel J. Krosky,Kartik Narayan,(unknown),John M. Sanders,Sujata Sharma,Min Xu,Antonella Converso	2
2	A novel glucosylceramide synthase inhibitor attenuates alpha synuclein pathology and lysosomal dysfunction in preclinical models of synucleinopathy 2021 ·Neurobiology of Disease ·(unknown),Sarah Jinn,Lihang Yao,(unknown),Monika Kandebo,Dawn Toolan,Nathan G. Hatcher,Lei Ma,Wei Lemaire,Gregory C. Adam,Christine Burlein,(unknown),(unknown),Marla L. Watt,(unknown),Mark E. Fraley,Robert E. Drolet,Jacob Marcus,Sean M. Smith	14
3	Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction 2021 ·ACS Medicinal Chemistry Letters ·Douglas C. Beshore,Gregory C. Adam,Richard J. O. Barnard,Christine Burlein,Steven N. Gallicchio,M. Katharine Holloway,Daniel J. Krosky,Wei Lemaire,Robert W. Myers,Sangita B. Patel,Michael A. Plotkin,David Powell,(unknown),Christopher D. Cox,Paul J. Coleman,Daniel J. Klein,S. E. Wolkenberg	14
4	Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase 2021 ·Nature Communications ·Robert P. Hayes,(unknown),Mark Mason,John C. Reid,Christine Burlein,Kira A. Armacost,David M. Tellers,Izzat T. Raheem,Anthony W. Shaw,Edward M. Murray,Philip M. McKenna,Pravien Abeywickrema,Sujata Sharma,S.M. Soisson,Daniel J. Klein	17
5	Discovery of a Distinct Chemical and Mechanistic Class of Allosteric HIV-1 Integrase Inhibitors with Antiretroviral Activity 2017 ·ACS Chemical Biology ·Christine Burlein,(unknown),Min Xu,(unknown),Mark W. Stahlhut,(unknown),Gregory C. Adam,(unknown),Daniel J. Klein,John M. Sanders,Kartik Narayan,Pravien Abeywickrema,(unknown),Steven S. Carroll,Jay A. Grobler,Sujata Sharma,Tracy L. Diamond,Antonella Converso,Daniel J. Krosky	11
6	Structural optimization of cyclic sulfonamide based novel HIV-1 protease inhibitors to picomolar affinities guided by X-ray crystallographic analysis 2014 ·Tetrahedron ·Ashit K. Ganguly,(unknown),Chih‐Hung Wang,(unknown),(unknown),(unknown),(unknown),Eun‐Hee Kang,(unknown),Steven S. Carroll,Christine Burlein,John F. Fay,Peter Orth,Corey Strickland	33
7	Development of a sensitive amplified luminescent proximity homogeneous assay to monitor the interactions between pTEFb and Tat 2014 ·Analytical Biochemistry ·Christine Burlein,(unknown),(unknown),Dennis J. Murphy,(unknown),Steve S. Carroll,Michael D. Miller,Ming‐Tain Lai	4
8	Design, Synthesis, and X-ray Crystallographic Analysis of a Novel Class of HIV-1 Protease Inhibitors 2011 ·Journal of Medicinal Chemistry ·Ashit K. Ganguly,(unknown),(unknown),(unknown),Chih‐Hung Wang,Eun‐Hee Kang,Yong Zhang,Andrew T. McPhail,Steven S. Carroll,Christine Burlein,Vandna Munshi,Peter Orth,Corey Strickland	67
9	Epsilon substituted lysinol derivatives as HIV-1 protease inhibitors 2010 ·Bioorganic & Medicinal Chemistry Letters ·Kristen L. Jones,M. Katharine Holloway,Hua-Poo Su,Steven S. Carroll,Christine Burlein,Sinoeun Touch,Daniel J. DiStefano,Rosa I. Sánchez,Theresa M. Williams,Joseph P. Vacca,Craig A. Coburn	7
10	Purification of untagged HIV-1 reverse transcriptase by affinity chromatography 2010 ·Protein Expression and Purification ·Meiqing Lu,Winnie Ngo,Ye Mei,Vandna Munshi,Christine Burlein,(unknown),Peter Williams,Daria J. Hazuda,Michael D. Miller,Jay A. Grobler,Tracy L. Diamond,Ming‐Tain Lai	10
11	Strategies towards Improving the Pharmacokinetic Profile of ε‐Substituted Lysinol‐Derived HIV Protease Inhibitors 2010 ·ChemMedChem ·Hemaka A. Rajapakse,Abbas M. Walji,Keith P. Moore,Hong Zhu,(unknown),Alison R. Gregro,(unknown),Christine Burlein,Sinoeun Touch,(unknown),Steven S. Carroll,Daniel J. DiStefano,Ming‐Tain Lai,Jay A. Grobler,Rosa I. Sánchez,Theresa M. Williams,Joseph P. Vacca,Philippe G. Nantermet	4
12	MK-5172, a Novel Macrocyclic Inhibitor of NS3/4a Protease Demonstrates Efficacy Against Viral Resistance in the Chimpanzee Model of Chronic Hepatitis C Virus Infection 2010 ·Antiviral Research ·(unknown),Steve S. Carroll,John A. McCauley,(unknown),Paul J. Coleman,Nigel J. Liverton,Christine Burlein,(unknown),Adam Gates,(unknown),Carolyn McHale,Mark W. Stahlhut,Christine Fandozzi,Daria J. Hazuda,Joe P. Vacca,David B. Olsen	1
13	Evaluation of MK-7009, A Novel Macrocyclic Inhibitor of NS3/4A Protease, in the Chimpanzee Model of Chronic Hepatitis C Virus Infection 2008 ·Antiviral Research ·(unknown),Donald J. Graham,L K Handt,Christine Fandozzi,Christine Burlein,Nigel J. Liverton,John A. McCauley,Joseph P. Vacca,Daria J. Hazuda,Steven S. Carroll,David B. Olsen	2
14	Synthesis and HCV inhibitory properties of 9-deaza- and 7,9-dideaza-7-oxa-2′-C-methyladenosine 2007 ·Bioorganic & Medicinal Chemistry ·Gabor Butora,David B. Olsen,Steven S. Carroll,Daniel R. McMasters,Christoph Schmitt,Joseph F. Leone,Mark W. Stahlhut,Christine Burlein,Malcolm MacCoss	24
15	A time-resolved, internally quenched fluorescence assay to characterize inhibition of hepatitis C virus nonstructural protein 3–4A protease at low enzyme concentrations 2007 ·Analytical Biochemistry ·Shi‐Shan Mao,Jillian DiMuzio,Carolyn McHale,Christine Burlein,David B. Olsen,Steven S. Carroll	23
16	Structure−Activity Relationship of Purine Ribonucleosides for Inhibition of Hepatitis C Virus RNA-Dependent RNA Polymerase 2004 ·Journal of Medicinal Chemistry ·Anne B. Eldrup,Charles Allerson,C. Frank Bennett,Sanjib Bera,Balkrishen Bhat,Neelima M. Bhat,Michele Bosserman,Jennifer L. Brooks,Christine Burlein,Steven S. Carroll,P. Dan Cook,Krista Getty,Malcolm MacCoss,Daniel R. McMasters,David B. Olsen,Thazha P. Prakash,Marija Prhavc,Quanlai Song,Joanne E. Tomassini,(unknown)	153
17	Electrochemiluminescence assay for basic carboxypeptidases: inhibition of basic carboxypeptidases and activation of thrombin-activatable fibrinolysis inhibitor 2003 ·Analytical Biochemistry ·Shi‐Shan Mao,Dennis Colussi,(unknown),Michele Bosserman,Christine Burlein,Stephen J. Gardell,Steven S. Carroll	27
18	Synthesis and Evaluation of Imidazole Acetic Acid Inhibitors of Activated Thrombin-Activatable Fibrinolysis Inhibitor as Novel Antithrombotics 2003 ·Journal of Medicinal Chemistry ·James C. Barrow,Philippe G. Nantermet,Shaun R. Stauffer,(unknown),(unknown),Shi‐Shan Mao,Steven S. Carroll,(unknown),Dennis Colussi,(unknown),Christine Burlein,Jacquelynn J. Cook,Gary R. Sitko,Philip R. Tiller,Cynthia Miller‐Stein,Mark J. Rose,Daniel R. McMasters,Joseph P. Vacca,Harold G. Selnick	36

About Christine Burlein

Christine Burlein is a scholar working on Virology, Infectious Diseases and Hepatology, having authored 18 papers that have together received 449 indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (12 papers), HIV Research and Treatment (6 papers) and Click Chemistry and Applications (5 papers). The work is most often cited by research in Hepatology (107 citations), Virology (61 citations) and Infectious Diseases (182 citations). Christine Burlein has collaborated with scholars based in United States and Canada. Frequent co-authors include Steven S. Carroll, David B. Olsen, Michele Bosserman, Daniel R. McMasters, Shi‐Shan Mao, Malcolm MacCoss, Marija Prhavc, Joanne E. Tomassini, Ashit K. Ganguly and C. Frank Bennett. Their work appears in journals such as Nature Communications, Analytical Biochemistry and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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