Izzat T. Raheem

2.0k total citations · 1 hit paper
26 papers, 1.5k citations indexed

About

Izzat T. Raheem is a scholar working on Molecular Biology, Organic Chemistry and Pharmacology. According to data from OpenAlex, Izzat T. Raheem has authored 26 papers receiving a total of 1.5k indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Molecular Biology, 10 papers in Organic Chemistry and 5 papers in Pharmacology. Recurrent topics in Izzat T. Raheem's work include Phosphodiesterase function and regulation (7 papers), Cholinesterase and Neurodegenerative Diseases (5 papers) and Catalytic C–H Functionalization Methods (3 papers). Izzat T. Raheem is often cited by papers focused on Phosphodiesterase function and regulation (7 papers), Cholinesterase and Neurodegenerative Diseases (5 papers) and Catalytic C–H Functionalization Methods (3 papers). Izzat T. Raheem collaborates with scholars based in United States, Netherlands and Canada. Izzat T. Raheem's co-authors include Eric N. Jacobsen, Parvinder S. Thiara, Emily A. Peterson, Steven N. Goodman, John D. Schreier, Paul Richardson, Daniel Richter, Barry R. Dillon, Arindam Chowdhury and Linda A. Peteanu and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Angewandte Chemie International Edition.

In The Last Decade

Izzat T. Raheem

26 papers receiving 1.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Enantioselective Pictet−Spengler-Type Cyclizations of Hydroxylactams: H-Bond Donor Catalysis by Anion Binding

2007 459 citations Izzat T. Raheem, Parvinder S. Thiara et al. Journal of the American Chemical Society profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Izzat T. Raheem United States	17	1.1k	468	266	127	112	26	1.5k
Jean‐Luc Parrain France	24	1.9k 1.7×	383 0.8×	230 0.9×	126 1.0×	79 0.7×	153	2.2k
Andrew F. Parsons United Kingdom	30	2.3k 2.0×	439 0.9×	217 0.8×	98 0.8×	73 0.7×	109	2.5k
Mahavir Prashad Switzerland	23	1.2k 1.1×	466 1.0×	333 1.3×	71 0.6×	106 0.9×	88	1.6k
Antal Csámpai Hungary	22	1.9k 1.7×	702 1.5×	271 1.0×	58 0.5×	152 1.4×	142	2.4k
Veerababurao Kavala Taiwan	25	1.9k 1.7×	401 0.9×	231 0.9×	112 0.9×	44 0.4×	100	2.0k
Okiko Miyata Japan	31	2.6k 2.3×	557 1.2×	192 0.7×	145 1.1×	83 0.7×	171	2.9k
John M. Keith United States	25	1.3k 1.2×	655 1.4×	435 1.6×	282 2.2×	180 1.6×	49	2.2k
Vinicio Zanirato Italy	23	1.5k 1.4×	592 1.3×	210 0.8×	88 0.7×	138 1.2×	78	1.9k
А. В. Варламов Russia	22	1.8k 1.6×	417 0.9×	122 0.5×	256 2.0×	59 0.5×	290	2.1k
Tarek Sammakia United States	27	2.1k 1.8×	635 1.4×	544 2.0×	144 1.1×	102 0.9×	63	2.4k

Countries citing papers authored by Izzat T. Raheem

Since Specialization

Citations

This map shows the geographic impact of Izzat T. Raheem's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Izzat T. Raheem with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Izzat T. Raheem more than expected).

Fields of papers citing papers by Izzat T. Raheem

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Izzat T. Raheem. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Izzat T. Raheem. The network helps show where Izzat T. Raheem may publish in the future.

Co-authorship network of co-authors of Izzat T. Raheem

This figure shows the co-authorship network connecting the top 25 collaborators of Izzat T. Raheem. A scholar is included among the top collaborators of Izzat T. Raheem based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Izzat T. Raheem. Izzat T. Raheem is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Smith, Sean M., Dawn Toolan, Monika Kandebo, et al.. (2024). Preclinical evaluation of MK-8189: A novel phosphodiesterase 10A inhibitor for the treatment of schizophrenia. Journal of Pharmacology and Experimental Therapeutics. 392(1). 100047–100047. 1 indexed citations

Raheem, Izzat T., Debbie Nahas, Michael Citron, et al.. (2024). Stabilized trimeric peptide immunogens of the complete HIV-1 gp41 N-heptad repeat and their use as HIV-1 vaccine candidates. Proceedings of the National Academy of Sciences. 121(22). e2317230121–e2317230121. 5 indexed citations

Layton, M. E., Jeffrey C. Kern, William D. Shipe, et al.. (2023). Discovery of MK-8189, a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizophrenia. Journal of Medicinal Chemistry. 66(2). 1157–1171. 22 indexed citations

Beshore, Douglas C., Andrew M. Haidle, Ashok Arasappan, et al.. (2022). Building a Culture of Medicinal Chemistry Knowledge Sharing. Journal of Medicinal Chemistry. 65(5). 3776–3785. 1 indexed citations

Smith, Sean M., Jason M. Uslaner, Monika Kandebo, et al.. (2022). P546. Preclinical Characterization and Phase 1 Evaluation of the Tolerability, Pharmacokinetics, and Enzyme Occupancy of MK-8189, a Novel PDE10A Inhibitor. Biological Psychiatry. 91(9). S309–S310. 1 indexed citations

Hayes, Robert P., Mark Mason, John C. Reid, et al.. (2021). Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase. Nature Communications. 12(1). 3040–3040. 17 indexed citations

Cox, Christopher D., Eric D. Hostetler, Jeffrey L. Evelhoch, et al.. (2015). Discovery of [C]MK-8193 as a PET tracer to measure target engagement of phosphodiesterase 10A (PDE10A) inhibitors. Bioorganic & Medicinal Chemistry Letters. 25(21). 4893–4898. 12 indexed citations

Raheem, Izzat T., Michael J. Breslin, Joseph G. Bruno, et al.. (2014). Discovery of piperidine ethers as selective orexin receptor antagonists (SORAs) inspired by filorexant. Bioorganic & Medicinal Chemistry Letters. 25(3). 444–450. 17 indexed citations

Peterson, Emily A., Barry R. Dillon, Izzat T. Raheem, et al.. (2014). Sustainable chromatography (an oxymoron?). Green Chemistry. 16(9). 4060–4075. 43 indexed citations

10.

Ruck, Rebecca T., Khateeta M. Emerson, Guy R. Humphrey, et al.. (2013). Merck’s Reaction Review Policy: An Exercise in Process Safety. Organic Process Research & Development. 17(12). 1611–1616. 21 indexed citations

11.

Nawrocki, Andrea R., Carlos G. Rodríguez, Dawn Toolan, et al.. (2013). Genetic Deletion and Pharmacological Inhibition of Phosphodiesterase 10A Protects Mice From Diet-Induced Obesity and Insulin Resistance. Diabetes. 63(1). 300–311. 41 indexed citations

12.

Bryan, Marian C., Barry R. Dillon, Lawrence G. Hamann, et al.. (2013). Sustainable Practices in Medicinal Chemistry: Current State and Future Directions. Journal of Medicinal Chemistry. 56(15). 6007–6021. 168 indexed citations

13.

Smith, Sean M., Jason M. Uslaner, Christopher D. Cox, et al.. (2012). The novel phosphodiesterase 10A inhibitor THPP-1 has antipsychotic-like effects in rat and improves cognition in rat and rhesus monkey. Neuropharmacology. 64. 215–223. 70 indexed citations

14.

Maligres, Peter E., Jing Li, Shane W. Krska, John D. Schreier, & Izzat T. Raheem. (2012). CO Cross‐Coupling of Activated Aryl and Heteroaryl Halides with Aliphatic Alcohols. Angewandte Chemie International Edition. 51(36). 9071–9074. 73 indexed citations

15.

Raheem, Izzat T., Michael J. Breslin, Christine Fandozzi, et al.. (2012). Discovery of tetrahydropyridopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorganic & Medicinal Chemistry Letters. 22(18). 5903–5908. 25 indexed citations

16.

Raheem, Izzat T., Parvinder S. Thiara, & Eric N. Jacobsen. (2008). Regio- and Enantioselective Catalytic Cyclization of Pyrroles onto N-Acyliminium Ions. Organic Letters. 10(8). 1577–1580. 138 indexed citations

17.

Raheem, Izzat T., Parvinder S. Thiara, Emily A. Peterson, & Eric N. Jacobsen. (2007). Enantioselective Pictet−Spengler-Type Cyclizations of Hydroxylactams: H-Bond Donor Catalysis by Anion Binding. Journal of the American Chemical Society. 129(44). 13404–13405. 459 indexed citations breakdown →

18.

Raheem, Izzat T. & Eric N. Jacobsen. (2005). Highly Enantioselective Aza‐Baylis–Hillman Reactions Catalyzed by Chiral Thiourea Derivatives. Advanced Synthesis & Catalysis. 347(11-13). 1701–1708. 154 indexed citations

19.

Jacobsen, Eric N. & Izzat T. Raheem. (2005). Thiourea Derivative Catalyzed Asymmetric Aza-Baylis-Hillman Reaction. Synfacts. 2006(1). 75–75. 1 indexed citations

20.

Chowdhury, Arindam, et al.. (2003). Stark Spectroscopy of Size-Selected Helical H-Aggregates of a Cyanine Dye Templated by Duplex DNA. Effect of Exciton Coupling on Electronic Polarizabilities. The Journal of Physical Chemistry A. 107(18). 3351–3362. 24 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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