Charles ffrench‐Constant

24.1k citations

178 papers · 18.3k indexed · 6 hit papers · h-index 77

Impact in

Developmental Neuroscience top 0.01%
- Neurogenesis and neuroplasticity mechanisms
Neurology top 0.05%
- Neuroinflammation and Neurodegeneration Mechanisms

Papers in

Developmental Neuroscience 91
- Neurogenesis and neuroplasticity mechanisms 91
Immunology and Allergy 60
- Cell Adhesion Molecules Research 60

Co-authors: Robin J.M. Franklin Martin Raff Holly Colognato Richard O. Hynes Anna Williams Andréas Faissner Richard Milner João B. Relvas
Journals: Journal of Neuroscience (17 papers)Glia (16 papers)Development (15 papers)Current Biology (6 papers)The Journal of Cell Biology (6 papers)
Partner nations: United Kingdom United States Germany

In The Last Decade

Charles ffrench‐Constant

177 papers receiving 18.1k citations

Hit Papers

6 papers align trajectories log scale

Altered human oligodendrocyte heterogeneity in multiple sclerosis 2019 · 510 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2019 Nature
2018 Nature Medicine
2017 Nature reviews. Neuroscience
2017 Nature
2013 Nature Neuroscience
2008 Nature reviews. Neuroscience

Peers

Countries citing papers authored by Charles ffrench‐Constant

Since Specialization

Citations

This map shows the geographic impact of Charles ffrench‐Constant's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Charles ffrench‐Constant with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Charles ffrench‐Constant more than expected).

Fields of papers citing papers by Charles ffrench‐Constant

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Charles ffrench‐Constant. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Charles ffrench‐Constant. The network helps show where Charles ffrench‐Constant may publish in the future.

Co-authors

The 25 scholars most cited alongside Charles ffrench‐Constant, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Charles ffrench‐Constant Line = papers co-authored together Charles ffrench‐Constant links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone Cell Reports ·Paula Bertolino Sanvezzo, Gaël Genet, Nicholas W. Chavkin, Umadevi Paila, Jennifer S. Fang, Hema Vasavada, 伊納正宏, Bipul R. Acharya, 장은정, G. Sradha, Katalin Lipták, 吕峰波, R. N. Nouran Mohammed Harazi, Patrick Hanna, Anne Eichmann, Jean‐Léon Thomas, Charles ffrench‐Constant, Karen K. Hirschi	2023	14
2	Biomimicking Fiber Platform with Tunable Stiffness to Study Mechanotransduction Reveals Stiffness Enhances Oligodendrocyte Differentiation but Impedes Myelination through YAP‐Dependent Regulation Small ·William Ong, V. N. Khramelashvili, Junquan Lin, Mui Ling Sharon Nai, Franco Scalenghe, Coline Pinese, Sreedharan Sajikumar, Chwee Teck Lim, Charles ffrench‐Constant, Marie E. Bechler, Sing Yian Chew	2020	30
3	Altered human oligodendrocyte heterogeneity in multiple sclerosis Nature ·Sarah Jäkel, Eneritz Agirre, Ana Mendanha Falcão, David van Bruggen, Ka Wai Lee, Irène Knuesel, Dheeraj Malhotra, Charles ffrench‐Constant, Anna Williams, Gonçalo Castelo‐Branco Hit paper breakdown →	2019	510
4	Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis Nature Medicine ·Ana Mendanha Falcão, David van Bruggen, Sueli Marques, Mandy Meijer, Sarah Jäkel, Eneritz Agirre, Samudyata Samudyata, Elisa M. Floriddia, Darya Vanichkina, Charles ffrench‐Constant, Anna Williams, André Ortlieb Guerreiro‐Cacais, Gonçalo Castelo‐Branco Hit paper breakdown →	2018	354
5	Seeing Is Believing: Myelin Dynamics in the Adult CNS Neuron ·Matthew Swire, Charles ffrench‐Constant	2018	15
6	Regenerating CNS myelin — from mechanisms to experimental medicines Nature reviews. Neuroscience ·Robin J.M. Franklin, Charles ffrench‐Constant Hit paper breakdown →	2017	446
7	Use of induced pluripotent stem-cell technology to understand photoreceptor cytoskeletal dynamics in retinitis pigmentosa The Lancet ·Roly Megaw, Carla Mellough, Alan F. Wright, Majlinda Lako, Charles ffrench‐Constant	2015	1
8	THE GROWTH FACTORS BDNF AND NEUREGULIN INDUCE NMDA RECEPTOR DEPENDENT MYELINATION BY OLIGODENDROCYTES, EMPLOYING AKT AND CREB SIGNALING Glia ·İsmail İvedi, A. Luzhynskaya, John H. Stockley, Zheng Wang, Charles ffrench‐Constant, Zahra Afsarian, Ragnhildur Thóra Káradóttir	2011	1
9	Integrin Activation Promotes Axon Growth on Inhibitory Chondroitin Sulfate Proteoglycans by Enhancing Integrin Signaling Journal of Neuroscience ·Chin Lik Tan, Jessica C. F. Kwok, Rickie Patani, Charles ffrench‐Constant, Siddharthan Chandran, James W. Fawcett	2011	129
10	Myelin Regeneration in Multiple Sclerosis: Targeting Endogenous Stem Cells Neurotherapeutics ·Jeffrey K. Huang, Stephen P.J. Fancy, Chao Zhao, David H. Rowitch, Charles ffrench‐Constant, Robin J.M. Franklin	2011	42
11	Quiescence and Activation of Stem and Precursor Cell Populations in the Subependymal Zone of the Mammalian Brain Are Associated with Distinct Cellular and Extracellular Matrix Signals Journal of Neuroscience ·Ilias Kazanis, Justin D. Lathia, Tegy J. Vadakkan, Deepika Chandra, Richard Wan, Seonga Lee, D. Mark Eckley, Takako Sasaki, Bruce L. Patton, Mark P. Mattson, Karen K. Hirschi, Mary E. Dickinson, Charles ffrench‐Constant	2010	138
12	Retinoid X receptor gamma signaling accelerates CNS remyelination Nature Neuroscience ·Jeffrey K. Huang, Andrew A. Jarjour, Brahim Nait‐Oumesmar, Christophe Kerninon, Anna Williams, Wojciech Krężel, Hiroyuki Kagechika, Julien Bauer, Chao Zhao, Anne Baron‐Van Evercooren, Pierre Chambon, Charles ffrench‐Constant, Robin J.M. Franklin	2010	423
13	Toll-Like Receptor 3 Is a Negative Regulator of Embryonic Neural Progenitor Cell Proliferation Journal of Neuroscience ·Justin D. Lathia, Eitan Okun, Sung‐Chun Tang, Kathleen J. Griffioen, Aiwu Cheng, Mohamed R. Mughal, Gloria Laryea, Pradeep Selvaraj, Charles ffrench‐Constant, Tim Magnus, Thiruma V. Arumugam, Mark P. Mattson	2008	163
14	Osteopontin is extensively expressed by macrophages following CNS demyelination but has a redundant role in remyelination Neurobiology of Disease ·Chao Zhao, Stephen P.J. Fancy, Charles ffrench‐Constant, Robin J.M. Franklin	2008	38
15	Identification of dystroglycan as a second laminin receptor in oligodendrocytes, with a role in myelination Development ·Holly Colognato, Pratima N. Patel, Zhen Wang, Jenne Relucio, Achyani Sujarwanta, David H. T. Harrison, Peter D. Yurchenco, Charles ffrench‐Constant	2007	80
16	Neurite outgrowth on a fibronectin isoform expressed during peripheral nerve regeneration is mediated by the interaction of paxillin with alpha4beta1 integrins Apollo (University of Cambridge) ·Mariette G. Vogelezang, Ulrike Förster, Jaewon Han, Mark H. Ginsberg, Charles ffrench‐Constant	2007	5
17	Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells Glia ·Jiang QQ, Justin D. Lathia, Chao Zhao, K. Sam Wells, Mahendra S. Rao, Charles ffrench‐Constant, Robin J.M. Franklin	2006	140
18	Enhancing Central Nervous System Remyelination in Multiple Sclerosis Neuron ·Monique Dubois‐Dalcq, Charles ffrench‐Constant, Robin J.M. Franklin	2005	95
19	Integrins mediate a neuronal survival signal for oligodendrocytes Current Biology ·Emma E. Frost, Philip C. Buttery, Richard Milner, Charles ffrench‐Constant	1999	84
20	The Macroglial Cells of the Rat Optic Nerve Annual Review of Neuroscience ·Robert H. Miller, Charles ffrench‐Constant, M C Raff	1989	164

About Charles ffrench‐Constant

Charles ffrench‐Constant is a scholar working on Developmental Neuroscience, Immunology and Allergy, Cellular and Molecular Neuroscience, Neurology and Cell Biology, having authored 178 papers that have together received 18.3k indexed citations. Recurring topics across this work include Neurogenesis and neuroplasticity mechanisms (91 papers), Cell Adhesion Molecules Research (60 papers), Neuroinflammation and Neurodegeneration Mechanisms (30 papers), Nerve injury and regeneration (29 papers), Axon Guidance and Neuronal Signaling (28 papers), RNA Research and Splicing (17 papers), Cellular Mechanics and Interactions (16 papers) and Signaling Pathways in Disease (15 papers). The work is most often cited by research in Developmental Neuroscience (7.7k citations), Neurology (4.2k citations), Immunology and Allergy (2.4k citations), Cellular and Molecular Neuroscience (5.2k citations) and Cell Biology (2.9k citations). Charles ffrench‐Constant has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Robin J.M. Franklin, Martin Raff, Holly Colognato, Richard O. Hynes, Anna Williams, Andréas Faissner, Richard Milner, João B. Relvas, Tim Czopka and Emmanuel Garcion. Their work appears in journals such as Journal of Neuroscience, Glia, Development, Current Biology and The Journal of Cell Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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