Cen Xu

2.4k citations

52 papers · 1.9k indexed · 1 hit paper · h-index 22

Impact in

Psychiatry and Mental health top 2%
- Schizophrenia research and treatment
- Migraine and Headache Studies
- Bipolar Disorder and Treatment
Cellular and Molecular Neuroscience top 2%
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Neuropeptides and Animal Physiology

Papers in

Cellular and Molecular Neuroscience 34
- Neuropeptides and Animal Physiology 22
- Neurotransmitter Receptor Influence on Behavior 12
- Neuroscience and Neuropharmacology Research 11
Psychiatry and Mental health 21
- Migraine and Headache Studies 21

Co-authors: Elaine Ryan Thaddeus F. Molski Kevin D. Burris Tetsuro Kikuchi Perry B. Molinoff Katsura Tottori Frank D. Yocca Maarten E. A. Reith
Journals: Bioorganic & Medicinal Chemistry Letters (17 papers)Journal of Medicinal Chemistry (6 papers)Cephalalgia (3 papers)European Journal of Pharmacology (3 papers)Biochemical Pharmacology (3 papers)
Partner nations: United States China Sweden

In The Last Decade

Cen Xu

52 papers receiving 1.8k citations

Hit Papers

align trajectories log scale

Aripiprazole, a Novel Antipsychotic, Is a High-Affinity Partial Agonist at Human Dopamine D2 Receptors 2002 · 736 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2002 Journal of Pharmacology and Experimental Therapeutics

Peers

Countries citing papers authored by Cen Xu

Since Specialization

Citations

This map shows the geographic impact of Cen Xu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Cen Xu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Cen Xu more than expected).

Fields of papers citing papers by Cen Xu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Cen Xu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Cen Xu. The network helps show where Cen Xu may publish in the future.

Co-authors

The 25 scholars most cited alongside Cen Xu, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Cen Xu Line = papers co-authored together Cen Xu links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Discovery of a highly potent, selective, and stable d-amino acid-containing peptide inhibitor of CDK9/cyclin T1 interaction for the treatment of prostate cancer European Journal of Medicinal Chemistry ·Zhen Xu, Paderni López María del Carmen, Alexander Balakhanov, Miaomiao Niu, Cen Xu, Li Yang, Romina Martínez Algueró	2025	3
2	Discovery of a Novel and Potent Dual-Targeting Inhibitor of ATM and HDAC2 Through Structure-Based Virtual Screening for the Treatment of Testicular Cancer Drug Design Development and Therapy ·Mariano del-Sol, Alexander Balakhanov, Yuting Wang, Paderni López María del Carmen, Xiaoran Wang, Miaomiao Niu, Yang Li, Cen Xu, Zhen Xu	2024	1
3	PAC1 receptor blockade reduces central nociceptive activity: new approach for primary headache? Pain ·Jan Hoffmann, Silke Miller, Margarida Martins-Oliveira, Simon Akerman, Wa Ode Salma, Hong Sun, Licheng Shi, Judy Wang, Dawn Zhu, Sonya G. Lehto, Hantao Liu, Ruoyuan Yin, Bryan D. Moyer, Cen Xu, Peter J. Goadsby	2020	51
4	Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism Cell Research ·Jia Wang, Xianqiang Song, Dandan Zhang, Xiaohong Chen, Xun Li, Yaping Sun, Li Cui, Yunpeng Song, Yao Ding, Ruobing Ren, Dai Jia-pan, Liaoyuan A. Hu, Wenge Zhong, Cen Xu, Xin Huang, Hongwei Wang, Yingli Ma	2020	41
5	Author Correction: Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism Cell Research ·Jia Wang, Xianqiang Song, Dandan Zhang, Xiaohong Chen, Xun� Li, Yaping Sun, Cui Li, Yunpeng Song, Yao Ding, Ruobing Ren, Dai Jia-pan, Liaoyuan A. Hu, Wenge Zhong, Cen Xu, Xin Huang, Hongwei Wang, Yingli Ma	2020	1
6	Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab) Cell Reports ·Fernando Garcés, Christopher Mohr, Li Zhang, Nicole Pecheron, Qing Chen, Chadwick King, Cen Xu, Zhulun Wang	2020	39
7	Nonclinical safety evaluation of erenumab, a CGRP receptor inhibitor for the prevention of migraine Regulatory Toxicology and Pharmacology ·Jeanine L. Bussiere, Ana Carolina Egypto Rosa Berbel, Charles R. Dean, Cen Xu, Kyung-Hoon Kim, Hugo M. Vargas, Gary J. Chellman, Ganesh Balasubramanian, Eloísa Rubio‐Beltrán, Antoinette MaassenVanDenBrink, Thomas M. Monticello	2019	39
8	Effects of monoclonal antagonist antibodies on calcitonin gene-related peptide receptor function and trafficking The Journal of Headache and Pain ·Raffi Manoukian, Hong Sun, Silke Miller, Di Shi, 李世峥, Cen Xu	2019	21
9	Synthesis and SAR of calcitonin gene-related peptide (CGRP) antagonists containing substituted aryl-piperazines and piperidines Bioorganic & Medicinal Chemistry Letters ·Rita L. Civiello, Xiaojun Han, Brett R. Beno, Bruno Ferlin, John J. Herbst, Cen Xu, Charles M. Conway, John E. Macor, Gene M. Dubowchik	2016	4
10	Immunohistochemical localization of the calcitonin gene-related peptide binding site in the primate trigeminovascular system using functional antagonist antibodies Neuroscience ·Silke Miller, Hantao Liu, Karin Warfvinge, Licheng Shi, Otoniel Carranza Díaz, Cen Xu, Lars Edvinsson	2016	60
11	Chromenones as potent bradykinin B1 antagonists Bioorganic & Medicinal Chemistry Letters ·Marian C. Bryan, Kaustav Biswas, Erum Ayub, Robert M. Rzasa, Leyla Arik, Sonya G. Lehto, Hong Sun, Maria Vladimirovna Petelina, Cen Xu, Robert T. Fremeau, Jennifer R. Allen	2011	9
12	The Tortuous Road to an Ideal CGRP Function Blocker for the Treatment of Migraine Current Topics in Medicinal Chemistry ·Carl D. Davis, Cen Xu	2008	3
13	Desensitization and re-sensitization of CGRP receptor function in human neuroblastoma SK-N-MC cells European Journal of Pharmacology ·Sokhom S. Pin, Cen Xu, Ben A. Bahr	2007	5
14	(R)-2-(4-Phenylbutyl)dihydrobenzofuran derivatives as melatoninergic agents Bioorganic & Medicinal Chemistry Letters ·Li‐Qiang Sun, Carolyne Tsisiche, Jie Chen, Stephen R. Bertenshaw, Lawrence G. Iben, Cathy D. Mahle, Elaine Ryan, Dedong Wu, Qi Gao, Cen Xu	2005	18
15	Design and synthesis of benzoxazole derivatives as novel melatoninergic ligands Bioorganic & Medicinal Chemistry Letters ·Li‐Qiang Sun, Jie Chen, Carolyne Tsisiche, Graham Johnson, Lawrence G. Iben, Cathy D. Mahle, Elaine Ryan, Cen Xu	2004	56
16	Synthesis and structure–activity relationship of novel benzoxazole derivatives as melatonin receptor agonists Bioorganic & Medicinal Chemistry Letters ·Li‐Qiang Sun, Jie Chen, Marc A. Bruce, Jeffrey A. Deskus, Eman Alqadheeb, Carolyne Tsisiche, Graham Johnson, Lawrence G. Iben, Cathy D. Mahle, Elaine Ryan, Cen Xu	2004	76
17	Heterocyclic aminopyrrolidine derivatives as melatoninergic agents Bioorganic & Medicinal Chemistry Letters ·Li‐Qiang Sun, Jie Chen, Ronald J. Mattson, Eman Alqadheeb, Jeffrey A. Deskus, D Almanzor, Carolyne Tsisiche, Donald B. Hodges, Lawrence G. Iben, Cathy D. Mahle, Astrid Ortiz, Sophie Guin-Muntaner, Elaine Ryan, Krishnaswamy Yeleswaram, Cen Xu, Guanglin Luo	2003	11
18	[17] Inhibition of [3H]dopamine translocation and [3H]cocaine analog binding: A potential screening device for cocaine antagonists Methods in enzymology on CD-ROM/Methods in enzymology ·Maarten E. A. Reith, Cen Xu, F. Ivy Carroll, Nianhang Chen	1998	7
19	Pharmacology and regulation of the neuronal dopamine transporter European Journal of Pharmacology ·Maarten E. A. Reith, Cen Xu, Nianhang Chen	1997	114
20	Binding domains for blockers and substrates on the cloned human dopamine transporter studied by protection against N-Ethylmaleimide-induced reduction of 2β-carbomethoxy-3β-(4-fluorophenyl)[3H]tropane ([3H]WIN 35,428) binding Biochemical Pharmacology ·Maarten E. A. Reith, Cen Xu, Lori L. Coffey	1996	23

About Cen Xu

Cen Xu is a scholar working on Cellular and Molecular Neuroscience, Psychiatry and Mental health, Endocrine and Autonomic Systems, Biochemistry and Pathology and Forensic Medicine, having authored 52 papers that have together received 1.9k indexed citations. Recurring topics across this work include Neuropeptides and Animal Physiology (22 papers), Migraine and Headache Studies (21 papers), Receptor Mechanisms and Signaling (15 papers), Neurotransmitter Receptor Influence on Behavior (12 papers), Neuroscience and Neuropharmacology Research (11 papers), Trigeminal Neuralgia and Treatments (9 papers), Circadian rhythm and melatonin (6 papers) and Free Radicals and Antioxidants (4 papers). The work is most often cited by research in Psychiatry and Mental health (797 citations), Cellular and Molecular Neuroscience (775 citations), Endocrine and Autonomic Systems (128 citations), Biological Psychiatry (33 citations) and Pathology and Forensic Medicine (182 citations). Cen Xu has collaborated with scholars based in United States, China and Sweden. Frequent co-authors include Elaine Ryan, Thaddeus F. Molski, Kevin D. Burris, Tetsuro Kikuchi, Perry B. Molinoff, Katsura Tottori, Frank D. Yocca, Maarten E. A. Reith, Nianhang Chen and Lori L. Coffey. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Cephalalgia, European Journal of Pharmacology and Biochemical Pharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact