Gene M. Dubowchik

3.9k citations

80 papers · 3.0k indexed · 1 hit paper · h-index 26

Molecular Biology top 5%
Oncology top 5%
Organic Chemistry top 5%
Radiology, Nuclear Medicine and Imaging top 2%
Psychiatry and Mental health top 2%

Co-authors: Raymond A. Firestone Pamela A. Trail Michael Walker Jay O. Knipe Kathleen Mosure Sandra J. Hofstead Charles M. Conway David Willner
Topics: Migraine and Headache Studies (21 papers)Neuropeptides and Animal Physiology (12 papers)Peptidase Inhibition and Analysis (10 papers)
Cited by: Psychiatry and Mental health Oncology Radiology, Nuclear Medicine and Imaging
Journals: New England Journal of Medicine Journal of the American Chemical Society Neurology
Partner nations: United States Germany Belgium

In The Last Decade

Gene M. Dubowchik

79 papers receiving 2.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Rimegepant, an Oral Calcitonin Gene–Related Peptide Receptor Antagonist, for Migraine

2019 265 citations Richard B. Lipton, Robert Croop et al. profile →

Peers

Countries citing papers authored by Gene M. Dubowchik

Since Specialization

Citations

This map shows the geographic impact of Gene M. Dubowchik's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gene M. Dubowchik with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gene M. Dubowchik more than expected).

Fields of papers citing papers by Gene M. Dubowchik

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gene M. Dubowchik. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gene M. Dubowchik. The network helps show where Gene M. Dubowchik may publish in the future.

Co-authorship network of co-authors of Gene M. Dubowchik

This figure shows the co-authorship network connecting the top 25 collaborators of Gene M. Dubowchik. A scholar is included among the top collaborators of Gene M. Dubowchik based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Gene M. Dubowchik. Gene M. Dubowchik is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Structure–activity relationship (SAR) studies on substituted N-(pyridin-3-yl)-2-amino-isonicotinamides as highly potent and selective glycogen synthase kinase-3 (GSK-3) inhibitors 2023 ·Bioorganic & Medicinal Chemistry Letters ·Guanglin Luo,Ling Chen,(unknown),Ying Han,Catherine R. Burton,Hong Xiao,Carol Krause,Yang Cao,(unknown),Kevin Kish,H.A. Lewis,John E. Macor,Gene M. Dubowchik	9
2	Cardiovascular Safety of Rimegepant 75 mg in 3 Randomized Clinical Trials and Systematic Evaluations from In Vitro, Ex Vivo, and In Vivo Nonclinical Assays (2141) 2020 ·Neurology ·Charles M. Conway,Robert Croop,Gene M. Dubowchik,Vladimir Coric,Richard B. Lipton	12
3	Antibody drug conjugates for treatment of breast cancer: Novel targets and diverse approaches in ADC design 2017 ·Pharmacology & Therapeutics ·Pamela A. Trail,Gene M. Dubowchik,Timothy B. Lowinger	98
4	Synthesis and SAR of calcitonin gene-related peptide (CGRP) antagonists containing substituted aryl-piperazines and piperidines 2016 ·Bioorganic & Medicinal Chemistry Letters ·Rita L. Civiello,Xiaojun Han,Brett R. Beno,(unknown),John J. Herbst,Cen Xu,Charles M. Conway,John E. Macor,Gene M. Dubowchik	4
5	Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core 2015 ·Bioorganic & Medicinal Chemistry Letters ·Prasanna Sivaprakasam,Xiaojun Han,Rita L. Civiello,(unknown),Kevin Kish,(unknown),H.A. Lewis,(unknown),(unknown),John A. Newitt,Eric T. Baldwin,Hong Xiao,Carol Krause,Hyunsoo Park,(unknown),Jonathan Lippy,Catherine R. Burton,David R. Langley,John E. Macor,Gene M. Dubowchik	100
6	Design and synthesis of potent antagonists containing rigid spirocyclic privileged structures for the CGRP receptor 2012 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Sokhom S. Pin,(unknown),(unknown),John E. Macor,Gene M. Dubowchik	8
7	Discovery of BMS-846372, a Potent and Orally Active Human CGRP Receptor Antagonist for the Treatment of Migraine 2012 ·ACS Medicinal Chemistry Letters ·Guanglin Luo,Ling Chen,Charles M. Conway,Rex Denton,(unknown),Michael Gulianello,Yanling Huang,Walter A. Kostich,Kimberley A. Lentz,Stephen E. Mercer,Richard Schartman,Laura J. Signor,(unknown),John E. Macor,Gene M. Dubowchik	32
8	Design, synthesis and evaluation of constrained tetrahydroimidazopyrimidine derivatives as antagonists of corticotropin-releasing factor type 1 receptor (CRF1R) 2010 ·Bioorganic & Medicinal Chemistry Letters ·Vivekananda M. Vrudhula,(unknown),Sokhom S. Pin,Kevin D. Burris,(unknown),Lawrence K. Fung,(unknown),Kaitlin E. Browman,Matthew T. Taber,Jie Zhang,John E. Macor,Gene M. Dubowchik	4
9	Synthesis and structure–activity relationship of imidazo[1,2-a]benzimidazoles as corticotropin-releasing factor 1 receptor antagonists 2005 ·Bioorganic & Medicinal Chemistry Letters ·Xiaojun Han,Sokhom S. Pin,Kevin D. Burris,Lawrence K. Fung,Stella Huang,Matthew T. Taber,Jie Zhang,Gene M. Dubowchik	34
10	An efficient sequence for the preparation of small secondary amine hydrochloride salts for focused library generation without need for distillation or chromatographic purification 2004 ·Bioorganic & Medicinal Chemistry Letters ·Gene M. Dubowchik,(unknown),Dmitry Zuev	9
11	Monoclonal antibody mediated intracellular targeting of tallysomycin S10b 2004 ·Bioorganic & Medicinal Chemistry Letters ·Michael Walker,Dalton King,R. A. Dalterio,Pamela A. Trail,Raymond A. Firestone,Gene M. Dubowchik	14
12	Optimization of CRF1R binding affinity of 2-(2,4,6-trichlorophenyl)-4-trifluoromethyl-5-aminomethylthiazoles through rapid and selective parallel synthesis 2004 ·Bioorganic & Medicinal Chemistry Letters ·Dmitry Zuev,(unknown),Sokhom S. Pin,Jie Zhang,Matthew T. Taber,Gene M. Dubowchik	3
13	Cephalosporin prodrugs of paclitaxel for immunologically specific activation by L-49-sFv-β-Lactamase fusion protein 2003 ·Bioorganic & Medicinal Chemistry Letters ·Vivekananda M. Vrudhula,David E. Kerr,Nathan O. Siemers,Gene M. Dubowchik,Peter D. Senter	24
14	High-Throughput Fluorescence Polarization Method for Identification of FKBP12 Ligands 2002 ·SLAS DISCOVERY ·(unknown),John J. Herbst,(unknown),Todd A. Verdoorn,Jonathan L. Ditta,Gene M. Dubowchik,Alexander Vinitsky	45
15	Synthesis of an immunoconjugate of camptothecin 2002 ·Bioorganic & Medicinal Chemistry Letters ·Michael Walker,Gene M. Dubowchik,Sandra J. Hofstead,Pamela A. Trail,Raymond A. Firestone	33
16	Doxorubicin immunoconjugates containing bivalent, lysosomally-Cleavable dipeptide linkages 2002 ·Bioorganic & Medicinal Chemistry Letters ·Gene M. Dubowchik,(unknown),Harold Mastalerz,Michael Walker,Raymond A. Firestone,Dalton King,Sandra J. Hofstead,David Willner,Shirley J. Lasch,Pamela A. Trail	30
17	Induction of cell death by the lysosomotropic detergent MSDH 2000 ·FEBS Letters ·Wei Li,Xi Yuan,(unknown),Helge Dalen,Gene M. Dubowchik,Raymond A. Firestone,Ulf T. Brunk	209
18	Cathepsin B-sensitive dipeptide prodrugs. 1. A model study of structural requirements for efficient release of doxorubicin 1998 ·Bioorganic & Medicinal Chemistry Letters ·Gene M. Dubowchik,Raymond A. Firestone	133
19	Improved Cytotoxicity of Antitumor Compounds Deliverable by the LDL Pathway 1995 ·Bioconjugate Chemistry ·Gene M. Dubowchik,Raymond A. Firestone	16
20	Reversal of doxorubicin resistance and catalytic neutralization of lysosomes by a lipophilic imidazole 1994 ·Biochimica et Biophysica Acta (BBA) - Biomembranes ·Gene M. Dubowchik,(unknown),(unknown),Raymond A. Firestone	16

About Gene M. Dubowchik

Gene M. Dubowchik is a scholar working on Biological Psychiatry, Behavioral Neuroscience and Psychiatry and Mental health, having authored 80 papers that have together received 3.0k indexed citations. Recurring topics across this work include Migraine and Headache Studies (21 papers), Neuropeptides and Animal Physiology (12 papers) and Peptidase Inhibition and Analysis (10 papers). The work is most often cited by research in Psychiatry and Mental health (466 citations), Oncology (719 citations) and Radiology, Nuclear Medicine and Imaging (596 citations). Gene M. Dubowchik has collaborated with scholars based in United States, Germany and Belgium. Frequent co-authors include Raymond A. Firestone, Pamela A. Trail, Michael Walker, Jay O. Knipe, Kathleen Mosure, Sandra J. Hofstead, Charles M. Conway, David Willner, Shirley J. Lasch and John E. Macor. Their work appears in journals such as New England Journal of Medicine, Journal of the American Chemical Society and Neurology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact