Cen Xie

9.6k total citations · 5 hit papers
97 papers, 5.6k citations indexed

About

Cen Xie is a scholar working on Molecular Biology, Epidemiology and Oncology. According to data from OpenAlex, Cen Xie has authored 97 papers receiving a total of 5.6k indexed citations (citations by other indexed papers that have themselves been cited), including 51 papers in Molecular Biology, 32 papers in Epidemiology and 24 papers in Oncology. Recurrent topics in Cen Xie's work include Liver Disease Diagnosis and Treatment (25 papers), Drug Transport and Resistance Mechanisms (20 papers) and Adipose Tissue and Metabolism (11 papers). Cen Xie is often cited by papers focused on Liver Disease Diagnosis and Treatment (25 papers), Drug Transport and Resistance Mechanisms (20 papers) and Adipose Tissue and Metabolism (11 papers). Cen Xie collaborates with scholars based in China, United States and Japan. Cen Xie's co-authors include Frank J. Gonzalez, Kristopher W. Krausz, Changtao Jiang, Andrew D. Patterson, Xiaoyan Chen, Dafang Zhong, Robert G. Nichols, Chad Brocker, Shogo Takahashi and Shannon Boehme and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Clinical Investigation and Nature Medicine.

In The Last Decade

Cen Xie

92 papers receiving 5.6k citations

Hit Papers

Intestinal farnesoid X receptor signaling promotes nonalc... 2014 2026 2018 2022 2014 2017 2015 2018 2022 100 200 300 400 500
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease
    2014 541 citations Changtao Jiang, Cen Xie et al. profile →
  2. Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota
    2017 510 citations Cen Xie, Yuan Tian et al. profile →
  3. Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction
    2015 455 citations Changtao Jiang, Cen Xie et al. Nature Communications profile →
  4. Intestine farnesoid X receptor agonist and the gut microbiota activate G‐protein bile acid receptor‐1 signaling to improve metabolism
    2018 410 citations Preeti Pathak, Cen Xie et al. profile →
  5. Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal
    2022 116 citations Tingying Jiao, Yuhong Luo et al. profile →

Peers

Cen Xie
Tiangang Li United States
Olivier Barbier Canada
Jinhan He China
Huijun Sun China
Sung Hwan Ki South Korea
Zhenzhou Jiang China
Ramiro Jover Spain
Gabriella Leonarduzzi Italy
Hor‐Yue Tan Hong Kong
Fiorella Biasi Italy
Tiangang Li United States
Cen Xie
Citations per year, relative to Cen Xie Cen Xie (= 1×) peers Tiangang Li

Countries citing papers authored by Cen Xie

Since Specialization
Citations

This map shows the geographic impact of Cen Xie's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Cen Xie with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Cen Xie more than expected).

Fields of papers citing papers by Cen Xie

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Cen Xie. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Cen Xie. The network helps show where Cen Xie may publish in the future.

Co-authorship network of co-authors of Cen Xie

This figure shows the co-authorship network connecting the top 25 collaborators of Cen Xie. A scholar is included among the top collaborators of Cen Xie based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Cen Xie. Cen Xie is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Guo, Xiaozhen, Zixuan Zhang, Cuina Li, et al.. (2025). Lipidomics reveals potential biomarkers and pathophysiological insights in the progression of diabetic kidney disease. Metabolism Open. 25. 100354–100354.
2.
Chen, Wenchao, Guanghao Zhu, Xue Zhang, et al.. (2025). Rationally engineered a universal far-red fluorogenic substrate of bile salt hydrolase for functional imaging and inhibitor screening. Chinese Chemical Letters. 37(4). 111320–111320.
3.
Jin, Can, Meixia Li, Huixian Chen, et al.. (2025). Arabinogalactan-like polysaccharide isolated from the flowers of Dendrobium officinale regulates the gut microbes and promotes vitamin K1, vitamin A, and vitamin B6 products. Carbohydrate Polymers. 366. 123660–123660. 2 indexed citations
4.
Sun, Wei Jia, Libo Jiang, Bing Shan, et al.. (2025). Cooperation of TRADD- and RIPK1-dependent cell death pathways in maintaining intestinal homeostasis. Nature Communications. 16(1). 1890–1890. 8 indexed citations
5.
Shi, Jingying, Yawen Liu, Zijia Zhang, et al.. (2024). Zexie-Baizhu Decoction ameliorates non-alcoholic fatty liver disease through gut-adipose tissue crosstalk. Journal of Ethnopharmacology. 337(Pt 1). 118700–118700. 10 indexed citations
6.
Guo, Yuhan, Xiaozhen Guo, Ziqi Liu, et al.. (2024). Ucp1 Ablation Improves Skeletal Muscle Glycolytic Function in Aging Mice. Advanced Science. 12(2). e2411015–e2411015. 6 indexed citations
7.
Zhang, Mengjiao, Yongxin Zhang, Gaihong Wang, et al.. (2024). FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis. Acta Pharmacologica Sinica. 45(11). 2313–2327. 4 indexed citations
8.
Wang, Yukun, Jing Li, Wu Li, et al.. (2023). Saikosaponins regulate bile acid excretion in mice liver and ileum by activating farnesoid X receptor and bile acid transporter. Phytotherapy Research. 37(10). 4572–4586. 5 indexed citations
9.
Guo, Xiaozhen, Jiawen Wang, Hualing Xu, et al.. (2023). Obesity induced disruption on diurnal rhythm of insulin sensitivity via gut microbiome-bile acid metabolism. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1869(1). 159419–159419. 6 indexed citations
10.
Lan, Li, Xinyu Liang, Yameng Liu, et al.. (2023). Saikosaponin D improves nonalcoholic fatty liver disease via gut microbiota-bile acid metabolism pathway. Food Science and Human Wellness. 13(5). 2703–2717. 3 indexed citations
11.
Chu, Hang, Yan Tan, Peng Li, et al.. (2023). Qing-Zhi-Tiao-Gan-Tang (QZTGT) prevents nonalcoholic steatohepatitis (NASH) by expression pattern correction. Journal of Ethnopharmacology. 317. 116665–116665. 1 indexed citations
12.
Wang, Jue, Xiaozhen Guo, Minjun Yu, et al.. (2023). Ootheca mantidis mitigates renal fibrosis in mice by the suppression of apoptosis via increasing the gut microbe Akkermansia muciniphila and modulating glutamine metabolism. Biomedicine & Pharmacotherapy. 166. 115434–115434. 12 indexed citations
13.
Xu, Hualing, Jiawen Wang, Yameng Liu, et al.. (2023). Development of a simultaneous quantification method for the gut microbiota-derived core nutrient metabolome in mice and its application in studying host-microbiota interaction. Analytica Chimica Acta. 1251. 341039–341039. 4 indexed citations
14.
Liu, Yameng, Hualing Xu, Xinyu Liang, et al.. (2022). Limosilactobacillus reuteri and caffeoylquinic acid synergistically promote adipose browning and ameliorate obesity-associated disorders. Microbiome. 10(1). 226–226. 34 indexed citations
15.
Zhang, You-Bo, Tingting Yan, Dongxue Sun, et al.. (2019). Rutaecarpine inhibits KEAP1-NRF2 interaction to activate NRF2 and ameliorate dextran sulfate sodium-induced colitis. Free Radical Biology and Medicine. 148. 33–41. 96 indexed citations
16.
Xie, Cen, Xiaoxia Gao, Dongxue Sun, et al.. (2018). Metabolic Profiling of the Novel Hypoxia-Inducible Factor 2α Inhibitor PT2385 In Vivo and In Vitro. Drug Metabolism and Disposition. 46(4). 336–345. 24 indexed citations
17.
Xie, Cen, Tomoki Yagai, Yuhong Luo, et al.. (2017). Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis. Nature Medicine. 23(11). 1298–1308. 128 indexed citations
18.
Pathak, Preeti, Hailiang Liu, Shannon Boehme, et al.. (2017). Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism. Journal of Biological Chemistry. 292(26). 11055–11069. 189 indexed citations
19.
Gao, Xiaoxia, Cen Xie, Yuanyuan Wang, et al.. (2016). The antiandrogen flutamide is a novel aryl hydrocarbon receptor ligand that disrupts bile acid homeostasis in mice through induction of Abcc4. Biochemical Pharmacology. 119. 93–104. 24 indexed citations
20.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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