Carl Frieden

16.8k total citations · 3 hit papers
221 papers, 13.5k citations indexed

About

Carl Frieden is a scholar working on Molecular Biology, Cell Biology and Materials Chemistry. According to data from OpenAlex, Carl Frieden has authored 221 papers receiving a total of 13.5k indexed citations (citations by other indexed papers that have themselves been cited), including 151 papers in Molecular Biology, 65 papers in Cell Biology and 51 papers in Materials Chemistry. Recurrent topics in Carl Frieden's work include Protein Structure and Dynamics (66 papers), Enzyme Structure and Function (50 papers) and Amino Acid Enzymes and Metabolism (26 papers). Carl Frieden is often cited by papers focused on Protein Structure and Dynamics (66 papers), Enzyme Structure and Function (50 papers) and Amino Acid Enzymes and Metabolism (26 papers). Carl Frieden collaborates with scholars based in United States, Russia and Spain. Carl Frieden's co-authors include Kanchan Garai, Dean W. Goddette, Bruce A. Barshop, Chris T. Zimmerle, Roberta F. Colman, Linda C. Kurz, Scott L. Crick, Paul Bock, Rohit V. Pappu and Sydney D. Hoeltzli and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Carl Frieden

220 papers receiving 12.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Analysis of numerical methods for computer simulation of kinetic processes: Development of KINSIM—A flexible, portable system

1983 551 citations Carl Frieden et al. profile →
Kinetic Aspects of Regulation of Metabolic Processes

1970 548 citations Carl Frieden Journal of Biological Chemistry profile →
ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions

2013 433 citations Kanchan Garai, Carl Frieden et al. Proceedings of the National Academy of Sciences profile →

Peers

Countries citing papers authored by Carl Frieden

Since Specialization

Citations

This map shows the geographic impact of Carl Frieden's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Carl Frieden with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Carl Frieden more than expected).

Fields of papers citing papers by Carl Frieden

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Carl Frieden. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Carl Frieden. The network helps show where Carl Frieden may publish in the future.

Co-authorship network of co-authors of Carl Frieden

This figure shows the co-authorship network connecting the top 25 collaborators of Carl Frieden. A scholar is included among the top collaborators of Carl Frieden based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Carl Frieden. Carl Frieden is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Functional insights from biophysical study of TREM2 interactions with apoE and Aβ _1‐42 2020 ·Alzheimer s & Dementia ·Daniel L. Kober, Melissa D. Stuchell‐Brereton, (unknown), (unknown), Michael R. Strickland, Deborah F. Steinberg, (unknown), Berevan Baban, David M. Holtzman, Carl Frieden, Jennifer Alexander‐Brett, Erik D. Roberson, Yuhua Song, Tom J. Brett	53
2	ApoE: The role of conserved residues in defining function 2014 ·Protein Science ·Carl Frieden	18
3	Structural differences between apoE3 and apoE4 may be useful in developing therapeutic agents for Alzheimer’s disease 2012 ·Proceedings of the National Academy of Sciences ·Carl Frieden, Kanchan Garai	92
4	Structural Differences Between Apolipoprotein E3 and E4 as Measured by 19F- NMR 2010 ·Biophysical Journal ·Kanchan Garai, (unknown), Berevan Baban, Carl Frieden	0
5	Dry molten globule intermediates and the mechanism of protein unfolding 2010 ·Proteins Structure Function and Bioinformatics ·Robert L. Baldwin, Carl Frieden, George D. Rose	103
6	A Lifetime of Kinetics 2008 ·Journal of Biological Chemistry ·Carl Frieden	4
7	Periplasmic Peptidyl Prolyl cis-trans Isomerases Are Not Essential for Viability, but SurA Is Required for Pilus Biogenesis in Escherichia coli 2005 ·Journal of Bacteriology ·Sheryl S. Justice, David A. Hunstad, (unknown), (unknown), Jerome S. Pinkner, James G. Bann, Carl Frieden, Thomas J. Silhavy, Scott J. Hultgren	119
8	The kinetics of conformational fluctuations in an unfolded protein measured by fluorescence methods 2005 ·Proceedings of the National Academy of Sciences ·Krishnananda Chattopadhyay, Elliot L. Elson, Carl Frieden	114
9	The Preparation of 19F-Labeled Proteins for NMR Studies 2004 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Carl Frieden, Sydney D. Hoeltzli, James G. Bann	78
10	The structure of nonvertebrate actin: Implications for the ATP hydrolytic mechanism 2003 ·Proceedings of the National Academy of Sciences ·S.M. Vorobiev, B.V. Strokopytov, David G. Drubin, Carl Frieden, Shoichiro Ono, John S. Condeelis, Peter A. Rubenstein, Steven C. Almo	132
11	Native Escherichia coli and murine dihydrofolate reductases contain late-folding non-native structures 1 1Edited by P. E. Wright 1999 ·Journal of Molecular Biology ·A. Clay Clark, Carl Frieden	22
12	[8] Purification of GroEL with low fluorescence background 1998 ·Methods in enzymology on CD-ROM/Methods in enzymology ·A. Clay Clark, Ragulan Ramanathan, Carl Frieden	28
13	Intestinal fatty acid binding protein: A specific residue in one turn appears to stabilize the native structure and be responsible for slow refolding 1997 ·Protein Science ·(unknown), Carl Frieden, Ragulan Ramanathan	31
14	Intestinal fatty acid binding protein: folding of fluorescein-modified proteins 1995 ·Biochemistry ·Carl Frieden, Nan Jiang, David P. Cistola	25
15	19F NMR Spectroscopy of [6-19F]Tryptophan-Labeled Escherichia coli Dihydrofolate Reductase: Equilibrium Folding and Ligand Binding Studies 1994 ·Biochemistry ·Sydney D. Hoeltzli, Carl Frieden	33
16	Numerical integration of rate equations by computer 1993 ·Trends in Biochemical Sciences ·Carl Frieden	50
17	The rate of formation of transition-state analogs in the active site of adenosine deaminase is encounter-controlled: implications for the mechanism 1992 ·Biochemistry ·Linda C. Kurz, (unknown), (unknown), Carl Frieden	52
18	pH-Induced changes in G-actin conformation and metal affinity 1988 ·Biochemistry ·Chris T. Zimmerle, Carl Frieden	21
19	Mechanism for nucleotide exchange in monomeric actin 1988 ·Biochemistry ·Carl Frieden, (unknown)	23
20	Formation of actin dimers as studied by small angle neutron scattering. 1986 ·Journal of Biological Chemistry ·Dean W. Goddette, Ed Uberbacher, Gerard J. Bunick, Carl Frieden	39

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact