Jeremy R. Knowles

17.7k total citations · 5 hit papers
229 papers, 14.5k citations indexed

About

Jeremy R. Knowles is a scholar working on Molecular Biology, Physiology and Organic Chemistry. According to data from OpenAlex, Jeremy R. Knowles has authored 229 papers receiving a total of 14.5k indexed citations (citations by other indexed papers that have themselves been cited), including 131 papers in Molecular Biology, 47 papers in Physiology and 40 papers in Organic Chemistry. Recurrent topics in Jeremy R. Knowles's work include Erythrocyte Function and Pathophysiology (46 papers), Enzyme Structure and Function (40 papers) and Protein Structure and Dynamics (30 papers). Jeremy R. Knowles is often cited by papers focused on Erythrocyte Function and Pathophysiology (46 papers), Enzyme Structure and Function (40 papers) and Protein Structure and Dynamics (30 papers). Jeremy R. Knowles collaborates with scholars based in United States, United Kingdom and Australia. Jeremy R. Knowles's co-authors include W. John Albery, Hagan Bayley, F.M. Richards, Joel G. Belasco, Robert L. Charnas, Jed F. Fisher, Shelley D. Copley, Stephen C. Blacklow, David N. Standring and Ronald T. Raines and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Jeremy R. Knowles

228 papers receiving 13.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Enzyme-Catalyzed Phosphoryl Transfer Reactions

1980 934 citations Jeremy R. Knowles profile →
Evolution of enzyme function and the development of catalytic efficiency

1976 482 citations W. John Albery, Jeremy R. Knowles Biochemistry profile →
Glutaraldehyde as a protein cross-linking reagent

1968 449 citations Jeremy R. Knowles et al. profile →
[8] Photoaffinity labeling

1977 441 citations Hagan Bayley, Jeremy R. Knowles Methods in enzymology on CD-ROM/Methods in enzymology profile →
Affinity Labelling of Antibodies with Aryl Nitrene as Reactive Group

1969 181 citations Jeremy R. Knowles et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jeremy R. Knowles United States	65	9.8k	3.1k	2.6k	1.7k	1.4k	229	14.5k
E.J. Dodson United Kingdom	56	16.3k 1.7×	5.5k 1.7×	1.5k 0.6×	675 0.4×	1.7k 1.2×	148	22.3k
Florante A. Quiocho United States	72	13.6k 1.4×	4.8k 1.5×	1.6k 0.6×	598 0.3×	2.3k 1.7×	205	19.1k
Dagmar Ringe United States	69	10.5k 1.1×	4.7k 1.5×	1.2k 0.5×	1.7k 1.0×	2.0k 1.4×	230	16.2k
Guy Dodson United Kingdom	61	10.4k 1.1×	2.5k 0.8×	825 0.3×	813 0.5×	1.8k 1.3×	159	13.4k
W. W. Cleland United States	55	8.7k 0.9×	2.8k 0.9×	2.0k 0.7×	740 0.4×	1.8k 1.3×	191	14.7k
P. Andrew Karplus United States	75	15.3k 1.6×	3.8k 1.2×	1.6k 0.6×	1.0k 0.6×	1.8k 1.3×	196	21.8k
Georg E. Schulz Germany	77	15.3k 1.6×	4.4k 1.4×	1.5k 0.6×	414 0.2×	1.1k 0.8×	242	20.9k
Gordon C. K. Roberts United Kingdom	64	7.1k 0.7×	2.0k 0.6×	1.1k 0.4×	634 0.4×	2.1k 1.5×	293	12.6k
A. A. Vagin Russia	14	13.4k 1.4×	4.8k 1.5×	1.2k 0.5×	661 0.4×	1.7k 1.2×	20	18.6k
Alexei A. Vagin United Kingdom	21	17.7k 1.8×	6.8k 2.2×	1.4k 0.5×	690 0.4×	1.9k 1.3×	24	24.6k

Countries citing papers authored by Jeremy R. Knowles

Since Specialization

Citations

This map shows the geographic impact of Jeremy R. Knowles's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jeremy R. Knowles with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jeremy R. Knowles more than expected).

Fields of papers citing papers by Jeremy R. Knowles

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jeremy R. Knowles. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jeremy R. Knowles. The network helps show where Jeremy R. Knowles may publish in the future.

Co-authorship network of co-authors of Jeremy R. Knowles

This figure shows the co-authorship network connecting the top 25 collaborators of Jeremy R. Knowles. A scholar is included among the top collaborators of Jeremy R. Knowles based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jeremy R. Knowles. Jeremy R. Knowles is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Lodi, Patricia J., Louise Chang, Jeremy R. Knowles, & Elizabeth A. Komives. (1994). Triosephosphate Isomerase Requires a Positively Charged Active Site: The Role of Lysine-12. Biochemistry. 33(10). 2809–2814. 65 indexed citations

Fanuel, Laurence, et al.. (1994). The precursor of the Streptomyces R61 DD‐peptidase containing a C‐terminal extension is inactive. FEBS Letters. 351(1). 49–52. 3 indexed citations

Mueller, Eugene G., Michael W. Crowder, Bruce A. Averill, & Jeremy R. Knowles. (1993). Purple acid phosphatase: a diiron enzyme that catalyzes a direct phospho group transfer to water. Journal of the American Chemical Society. 115(7). 2974–2975. 73 indexed citations

Seidel, H. Martin, David L. Pompliano, & Jeremy R. Knowles. (1992). Exons as Microgenes?. Science. 257(5076). 1489–1490. 23 indexed citations

Lodi, Patricia J. & Jeremy R. Knowles. (1991). Neutral imidazole is the electrophile in the reaction catalyzed by triosephosphate isomerase: structural origins and catalytic implications. Biochemistry. 30(28). 6948–6956. 123 indexed citations

Hermes, Jeffrey D., Stephen C. Blacklow, & Jeremy R. Knowles. (1990). Searching sequence space by definably random mutagenesis: improving the catalytic potency of an enzyme.. Proceedings of the National Academy of Sciences. 87(2). 696–700. 92 indexed citations

Bender, Steven L., Shujaath Mehdi, & Jeremy R. Knowles. (1989). Dehydroquinate synthase: the role of divalent metal cations and of nicotinamide adenine dinucleotide in catalysis. Biochemistry. 28(19). 7555–7560. 49 indexed citations

Nickbarg, Elliott & Jeremy R. Knowles. (1988). Triosephosphate isomerase: energetics of the reaction catalyzed by the yeast enzyme expressed in Escherichia coli. Biochemistry. 27(16). 5939–5947. 57 indexed citations

Albery, W. John & Jeremy R. Knowles. (1987). Energetics of enzyme catalysis. I. Isotopic experiments, enzyme interconversion, and oversaturation. Journal of Theoretical Biology. 124(2). 137–171. 10 indexed citations

10.

Raines, Ronald T. & Jeremy R. Knowles. (1987). Enzyme relaxation in the reaction catalyzed by triosephosphate isomerase: detection and kinetic characterization of two unliganded forms of the enzyme. Biochemistry. 26(22). 7014–7020. 11 indexed citations

11.

Raines, Ronald T., et al.. (1986). The kinetic consequences of altering the catalytic residues of triosephosphate isomerase. Philosophical Transactions of the Royal Society of London Series A Mathematical and Physical Sciences. 317(1540). 371–380. 2 indexed citations

12.

Knowles, Jeremy R., et al.. (1982). Pyruvate kinase: is the mechanism of phospho transfer associative or dissociative?. Biochemistry. 21(25). 6335–6340. 44 indexed citations

13.

Charnas, Robert L. & Jeremy R. Knowles. (1981). Inhibition of the RTEM .beta.-lactamase from Escherichia coli. Interaction of the enzyme with derivatives of olivanic acid. Biochemistry. 20(10). 2732–2737. 57 indexed citations

14.

Belasco, Joel G., et al.. (1978). Critical ionization states in the reaction catalyzed by triosephosphate isomerase. Biochemistry. 17(15). 2971–2978. 30 indexed citations

15.

Bayley, Hagan & Jeremy R. Knowles. (1977). [8] Photoaffinity labeling. Methods in enzymology on CD-ROM/Methods in enzymology. 46. 69–114. 441 indexed citations breakdown →

16.

Knowles, Jeremy R. & William P. Jencks. (1976). The Intrinsic Pk_A-Values of Functional Groups in Enzymes: Improper Deductions from the Ph-Dependence of Steady-State Parameter. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich). 4(2). 165–173. 157 indexed citations

17.

Albery, W. John & Jeremy R. Knowles. (1976). Deuterium and tritium exchange in enzyme kinetics. Biochemistry. 15(25). 5588–5600. 51 indexed citations

18.

Webb, Martin R. & Jeremy R. Knowles. (1974). The existence of an electrophilic component in the reaction catalysed by triose phosphate isomerase. Biochemical Journal. 141(2). 589–592. 21 indexed citations

19.

Knowles, Jeremy R., et al.. (1972). The Number of Catalytically Essential Carboxyl Groups in Pepsin. European Journal of Biochemistry. 31(3). 510–517. 48 indexed citations

20.

Greenwell, Pamela, et al.. (1969). The inhibition of pepsin-catalysed reactions by products and product analogues. Kinetic evidence for ordered release of products. Biochemical Journal. 113(2). 363–368. 11 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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