Bruce Wightman

6.0k citations

23 papers · 4.0k indexed · 1 hit paper · h-index 15

Impact in

Aging top 0.2%
- Genetics, Aging, and Longevity in Model Organisms
Cancer Research top 0.5%
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research

Papers in

Aging 19
- Genetics, Aging, and Longevity in Model Organisms 19
Endocrine and Autonomic Systems 6
- Circadian rhythm and melatonin 6

Co-authors: Gary Ruvkun Ilho Ha Prema Arasu Gian Garriga Thomas R. Bürglin Fred W. Wolf Ming‐Shiu Hung Amy T. Hark
Journals: Development (4 papers)Developmental Biology (4 papers)Genes & Development (3 papers)Neuron (1 paper)BMC Molecular Biology (1 paper)
Partner nations: United States Switzerland France

In The Last Decade

Bruce Wightman

22 papers receiving 3.9k citations

Hit Papers

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Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans 1993 · 3.2k citations

Peers

Countries citing papers authored by Bruce Wightman

Since Specialization

Citations

This map shows the geographic impact of Bruce Wightman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bruce Wightman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bruce Wightman more than expected).

Fields of papers citing papers by Bruce Wightman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bruce Wightman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bruce Wightman. The network helps show where Bruce Wightman may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Bruce Wightman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Bruce Wightman Line = papers co-authored together Bruce Wightman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	It's about time: the heterochronic background for the 2024 Nobel Prize in Physiology or Medicine Disease Models & Mechanisms ·Bruce Wightman	2024	0
2	Parallel Rap1>RalGEF>Ral and Ras signals sculpt the C. elegans nervous system Developmental Biology ·Кренкель Теодор Эрнстович, Lishan Asefa, Bruce Wightman, David J. Reiner	2021	1
3	A tissue-specific enhancer of the C. elegans nhr-67/tailless gene drives coordinated expression in uterine stem cells and the differentiated anchor cell Gene Expression Patterns ·M. Pubert, Katarina Liberatore, Silvia Borreguero Nieto, Cecilia de la Carrera, 최성근, رشا محمد السيد شبانه, Tala Bukhari, О. М. Міхальов, Sakae Kimura, Bruce Wightman	2018	6
4	Conserved and Exapted Functions of Nuclear Receptors in Animal Development PubMed ·M. Pubert, Soria Lm, Bruce Wightman	2017	22
5	Analysis of C. elegans NR2E nuclear receptors defines three conserved clades and ligand-independent functions BMC Evolutionary Biology ·智彰佐土原, Swaraj Abhishek Naik, George Μ. Baer, Kristy Reinert, Giovanna Capelli, Sakae Kimura, Bruce Wightman	2012	10
6	Integration of bioinformatics into an undergraduate biology curriculum and the impact on development of mathematical skills Biochemistry and Molecular Biology Education ·Bruce Wightman, Amy T. Hark	2012	20
7	The tailless ortholog nhr-67 functions in the development of the C. elegans ventral uterus Developmental Biology ·W. Koscielniak, John Schocken, Sandrine Jacob, Esteban Serrano-Llamas, Yongbing Wu, Р М Кисловец, George Μ. Baer, Sakae Kimura, G. A. Lavrinenko, Bernard Lakowski, Bruce Wightman	2011	23
8	The C. elegans tailless ortholog nhr-67 functions in uterus and tail development Developmental Biology ·John Schocken, W. Koscielniak, Naofumi SHIBASAKI, Stephanie Eng, Adriano Savastano de Sant ́Anna, V. K. Brown, P. Zhang, Aruna Singam, G. A. Lavrinenko, Bruce Wightman	2008	1
9	Specificity of DNA-binding by the FAX-1 and NHR-67 nuclear receptors of Caenorhabditis elegans is partially mediated via a subclass-specific P-box residue BMC Molecular Biology ·Stephen DeMeo, Deepak S. Parmar, EL Barrett-Connor, Eric L. Smith, Siti Amirah Azam, Kristy Reinert, Sakae Kimura, Bruce Wightman	2008	14
10	The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans SHILAP Revista de lepidopterología ·(unknown), (unknown), (unknown), Bruce Wightman, (unknown), (unknown), (unknown), Christa Rhiner, Dimitrios Bourikas, Esther T. Stoeckli, Gian Garriga, H. Robert Horvitz, Michael O. Hengartner	2006	29
11	The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans Journal of Biology ·G. Yedwab, Suzanne Tharin, Yishi Jin, Bruce Wightman, Mona S. Spector, David Meili, Oleg SOLOMON, Christa Rhiner, Dimitrios Bourikas, Esther T. Stoeckli, Gian Garriga, H. Robert Horvitz, Michael O. Hengartner	2006	2
12	The C. elegans nuclear receptor gene fax-1 and homeobox gene unc-42 coordinate interneuron identity by regulating the expression of glutamate receptor subunits and other neuron-specific genes Developmental Biology ·Bruce Wightman, M.L. Sumabindu, Nicole Carmean, 智彰佐土原, Sakae Kimura	2005	38
13	The fax-1 nuclear hormone receptor regulates axon pathfinding and neurotransmitter expression Development ·Ian Vorhees, Sir Philip Preston, Simal Kurumoglu, Gian Garriga, Bruce Wightman	2000	57
14	vab-8 Is a Key Regulator of Posteriorly Directed Migrations in C. elegans and Encodes a Novel Protein with Kinesin Motor Similarity Neuron ·Fred W. Wolf, Ming‐Shiu Hung, Bruce Wightman, Rosemary Sassoon, Gian Garriga	1998	54
15	Genes that guide growth cones along the C. elegans ventral nerve cord Development ·Bruce Wightman, M. Graf, Gian Garriga	1997	63
16	The C. elegans gene vab-8 guides posteriorly directed axon outgrowth and cell migration Development ·Bruce Wightman, Scott G. Clark, Tianliang Li, Wayne C. Forrester, Andres V. Maricq, Cornelia I. Bargmann, Gian Garriga	1996	57
17	A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation. Genes & Development ·Ilho Ha, Bruce Wightman, Gary Ruvkun	1996	185
18	Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans Cell ·Bruce Wightman, Ilho Ha, Gary Ruvkun Hit paper breakdown →	1993	3168
19	Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development. Genes & Development ·Bruce Wightman, Thomas R. Bürglin, Н. В. Ефимова, Prema Arasu, Gary Ruvkun	1991	153
20	Temporal regulation of lin-14 by the antagonistic action of two other heterochronic genes, lin-4 and lin-28. Genes & Development ·Prema Arasu, Bruce Wightman, Gary Ruvkun	1991	92

About Bruce Wightman

Bruce Wightman is a scholar working on Aging, Endocrine and Autonomic Systems, Cellular and Molecular Neuroscience, Physiology and Molecular Biology, having authored 23 papers that have together received 4.0k indexed citations. Recurring topics across this work include Genetics, Aging, and Longevity in Model Organisms (19 papers), Circadian rhythm and melatonin (6 papers), Spaceflight effects on biology (5 papers), Photosynthetic Processes and Mechanisms (5 papers), Estrogen and related hormone effects (3 papers), Plant Stress Responses and Tolerance (3 papers), RNA Research and Splicing (3 papers) and Reproductive Biology and Fertility (2 papers). The work is most often cited by research in Aging (593 citations), Cancer Research (2.5k citations), Molecular Biology (3.2k citations), Endocrine and Autonomic Systems (139 citations) and Cellular and Molecular Neuroscience (216 citations). Bruce Wightman has collaborated with scholars based in United States, Switzerland and France. Frequent co-authors include Gary Ruvkun, Ilho Ha, Prema Arasu, Gian Garriga, Thomas R. Bürglin, Fred W. Wolf, Ming‐Shiu Hung, Amy T. Hark, Scott G. Clark and Wayne C. Forrester. Their work appears in journals such as Development, Developmental Biology, Genes & Development, Neuron and BMC Molecular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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