Bruce Freimark

2.7k total citations · 2 hit papers
43 papers, 2.1k citations indexed

About

Bruce Freimark is a scholar working on Immunology, Molecular Biology and Oncology. According to data from OpenAlex, Bruce Freimark has authored 43 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 29 papers in Immunology, 11 papers in Molecular Biology and 11 papers in Oncology. Recurrent topics in Bruce Freimark's work include Phagocytosis and Immune Regulation (21 papers), Immune cells in cancer (10 papers) and Immunotherapy and Immune Responses (8 papers). Bruce Freimark is often cited by papers focused on Phagocytosis and Immune Regulation (21 papers), Immune cells in cancer (10 papers) and Immunotherapy and Immune Responses (8 papers). Bruce Freimark collaborates with scholars based in United States, United Kingdom and Australia. Bruce Freimark's co-authors include Tetsuichiro Inai, Virginia Yao, David R. Shalinsky, Barbara Sennino, Tsutomu Nakahara, Michael R. Mancuso, Donald M. McDonald, Dana D. Hu‐Lowe, Rachel Davis and Shaun O’Brien and has published in prestigious journals such as Nucleic Acids Research, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Bruce Freimark

41 papers receiving 2.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Rapid vascular regrowth in tumors after reversal of VEGF inhibition

2006 641 citations Michael R. Mancuso, Rachel Davis et al. Journal of Clinical Investigation profile →
Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer

2016 532 citations Jay W. Carlson, Rolf A. Brekken et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Bruce Freimark United States	17	997	785	458	334	240	43	2.1k
Kenneth W. Harder Canada	26	1.5k 1.5×	1.4k 1.8×	504 1.1×	177 0.5×	121 0.5×	49	2.9k
Eugenio Gallo Italy	27	687 0.7×	489 0.6×	548 1.2×	167 0.5×	165 0.7×	94	2.3k
Wilfred W. Raymond United States	21	803 0.8×	1.1k 1.4×	394 0.9×	349 1.0×	215 0.9×	37	2.2k
Niels Bovenschen Netherlands	29	945 0.9×	1.1k 1.4×	531 1.2×	247 0.7×	114 0.5×	83	2.7k
Andréas Tsapis France	29	885 0.9×	1.3k 1.6×	607 1.3×	370 1.1×	110 0.5×	71	2.8k
Cary D. Austin United States	22	1.1k 1.1×	555 0.7×	395 0.9×	137 0.4×	245 1.0×	38	2.6k
Sylvie Giuriato France	21	1.3k 1.3×	419 0.5×	388 0.8×	299 0.9×	142 0.6×	35	2.2k
Mitsunobu Sato Japan	31	1.2k 1.2×	819 1.0×	890 1.9×	475 1.4×	226 0.9×	110	2.8k
Marie‐Josèphe Rabiet France	29	1.3k 1.3×	687 0.9×	200 0.4×	242 0.7×	183 0.8×	48	2.3k
Ines Gütgemann Germany	25	1.3k 1.3×	1.2k 1.5×	1.1k 2.4×	368 1.1×	332 1.4×	60	3.0k

Countries citing papers authored by Bruce Freimark

Since Specialization

Citations

This map shows the geographic impact of Bruce Freimark's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bruce Freimark with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bruce Freimark more than expected).

Fields of papers citing papers by Bruce Freimark

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bruce Freimark. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bruce Freimark. The network helps show where Bruce Freimark may publish in the future.

Co-authorship network of co-authors of Bruce Freimark

This figure shows the co-authorship network connecting the top 25 collaborators of Bruce Freimark. A scholar is included among the top collaborators of Bruce Freimark based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Bruce Freimark. Bruce Freimark is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Freimark, Bruce, et al.. (2023). Nano-pulse stimulation™ therapy (NPS™) is superior to cryoablation in clearing murine melanoma tumors. Frontiers in Oncology. 12. 948472–948472. 5 indexed citations

Belzile, Olivier, Xianming Huang, Jian Gong, et al.. (2018). Antibody targeting of phosphatidylserine for the detection and immunotherapy of cancer. ImmunoTargets and Therapy. Volume 7. 1–14. 39 indexed citations

Mediavilla-Varela, Melanie, Jenny Kreahling, Bruce Freimark, et al.. (2017). Effect of bavituximab in combination with nivolumab on tumor immune response in a 3D ex vivo system of lung cancer patients.. Journal of Clinical Oncology. 35(15_suppl). e23091–e23091. 1 indexed citations

Freimark, Bruce, Jian Gong, Dan Ye, et al.. (2016). Antibody-Mediated Phosphatidylserine Blockade Enhances the Antitumor Responses to CTLA-4 and PD-1 Antibodies in Melanoma. Cancer Immunology Research. 4(6). 531–540. 21 indexed citations

Gray, Michael J., et al.. (2016). Abstract B27: Targeting of phosphatidylserine by monoclonal antibody ch1N11 enhances the antitumor activity of immune checkpoint inhibitor PD-1/PD-L1 therapy in orthotopic murine breast cancer models. Molecular Cancer Research. 14(2_Supplement). B27–B27. 1 indexed citations

Gong, Jian, Michael J. Gray, Jeff Hutchins, & Bruce Freimark. (2016). Anti-Tumor Responses By Ibrutinib and Anti-PD-1 Blockade Is Enhanced By Phosphatidylserine-Targeting Antibody Therapy. Blood. 128(22). 5379–5379. 1 indexed citations

Gray, Michael J., Jian Gong, Michaela M.S. Hatch, et al.. (2016). Phosphatidylserine-targeting antibodies augment the anti-tumorigenic activity of anti-PD-1 therapy by enhancing immune activation and downregulating pro-oncogenic factors induced by T-cell checkpoint inhibition in murine triple-negative breast cancers. Breast Cancer Research. 18(1). 50–50. 63 indexed citations

Rojko, Jennifer L., Mark G. Evans, Bora Han, et al.. (2014). Formation, Clearance, Deposition, Pathogenicity, and Identification of Biopharmaceutical-related Immune Complexes. Toxicologic Pathology. 42(4). 725–764. 98 indexed citations

Freimark, Bruce, et al.. (2007). Targeting of humanized antibody D93 to sites of angiogenesis and tumor growth by binding to multiple epitopes on denatured collagens. Molecular Immunology. 44(15). 3741–3750. 16 indexed citations

10.

Mancuso, Michael R., Rachel Davis, Scott M. Norberg, et al.. (2006). Rapid vascular regrowth in tumors after reversal of VEGF inhibition. Journal of Clinical Investigation. 116(10). 2610–2621. 641 indexed citations breakdown →

11.

Blezinger, Paul, et al.. (1998). Target Specific Optimization of Cationic Lipid-Based Systems for Pulmonary Gene Therapy. Pharmaceutical Research. 15(9). 1340–1347. 37 indexed citations

12.

Freimark, Bruce, et al.. (1998). Cationic Lipids Enhance Cytokine and Cell Influx Levels in the Lung Following Administration of Plasmid: Cationic Lipid Complexes. The Journal of Immunology. 160(9). 4580–4586. 130 indexed citations

13.

Pillai, Ravi, Karel Petrak, Paul Blezinger, et al.. (1998). Ultrasonic Nebulization of Cationic Lipid-Based Gene Delivery Systems for Airway Administration. Pharmaceutical Research. 15(11). 1743–1747. 24 indexed citations

14.

Wright, Stephen W., Joseph J. Petraitis, Bruce Freimark, et al.. (1996). 2,5-Diarylisothiazolone: novel inhibitors of cytokine-induced cartilage destruction. Bioorganic & Medicinal Chemistry. 4(6). 851–858. 12 indexed citations

15.

Arner, Elizabeth C., Michael A. Pratta, Bruce Freimark, et al.. (1996). Isothiazolones interfere with normal matrix metalloproteinase activation and inhibit cartilage proteoglycan degradation. Biochemical Journal. 318(2). 417–424. 8 indexed citations

16.

Wright, Stephen W., Joseph J. Petraitis, Douglas G. Batt, et al.. (1995). Metabolism resistant isothiazolone inhibitors of cartilage breakdown. Bioorganic & Medicinal Chemistry. 3(3). 227–234. 10 indexed citations

17.

Rosenfeld, Stuart A., et al.. (1994). Production of human matrix metalloproteinase 3 (stromelysin) in Escherichia coli. Gene. 139(2). 281–286. 14 indexed citations

18.

Wright, Stephen W., Joseph J. Petraitis, Matthew M. Abelman, et al.. (1994). Heteroaryl-Fused 2-Phenylisothiazolone Inhibitors of Cartilage Breakdown. Journal of Medicinal Chemistry. 37(19). 3071–3078. 16 indexed citations

19.

Goodman, Richard B., Elza C. de Bruin, Randine L. Dowling, et al.. (1993). IL‐1 and its role in rat carrageenan pleurisy. Mediators of Inflammation. 2(1). 33–39. 9 indexed citations

20.

Freimark, Bruce, et al.. (1989). Nucleotide sequence of a uniquely expressed human T cell receptor β chain variable region gene (Vβ) in Siogren's Syndrome. Nucleic Acids Research. 17(1). 455–455. 7 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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