Bradley C. Pearce

2.4k citations

33 papers · 1.5k indexed · h-index 18

Co-authors: J. J. Wright Asaf A. Qureshi David A. Gordon R.A. Parker Rex A. Parker Charles E. Elson A. Gapor David M. Peterson
Topics: Computational Drug Discovery Methods (5 papers)Cholesterol and Lipid Metabolism (4 papers)Synthesis and Biological Evaluation (4 papers)
Cited by: Biochemistry Nutrition and Dietetics Organic Chemistry
Journals: Journal of Biological Chemistry Biochemical and Biophysical Research Communications Journal of Medicinal Chemistry
Partner nations: United States Germany Malaysia

In The Last Decade

Bradley C. Pearce

33 papers receiving 1.4k citations

Peers

Countries citing papers authored by Bradley C. Pearce

Since Specialization

Citations

This map shows the geographic impact of Bradley C. Pearce's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bradley C. Pearce with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bradley C. Pearce more than expected).

Fields of papers citing papers by Bradley C. Pearce

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bradley C. Pearce. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bradley C. Pearce. The network helps show where Bradley C. Pearce may publish in the future.

Co-authorship network of co-authors of Bradley C. Pearce

This figure shows the co-authorship network connecting the top 25 collaborators of Bradley C. Pearce. A scholar is included among the top collaborators of Bradley C. Pearce based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Bradley C. Pearce. Bradley C. Pearce is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Using yeast surface display to engineer a soluble and crystallizable construct of hematopoietic progenitor kinase 1 (HPK1) 2020 ·Acta Crystallographica Section F Structural Biology Communications ·Wai Leung Lau,Bradley C. Pearce,(unknown),(unknown),Dianlin Xie,Mian Gao,Frank Marsilio,ChiehYing Y. Chang,Max Ruzanov,J.K. Muckelbauer,John A. Newitt,Daša Lipovšek,S. Sheriff	11
2	Design and synthesis of a novel series of (1′S,2R,4′S)-3H-4′-azaspiro[benzo[4,5]imidazo[2,1-b]oxazole-2,2′-bicyclo[2.2.2]octanes] with high affinity for the α7 neuronal nicotinic receptor 2017 ·Bioorganic & Medicinal Chemistry Letters ·James A. Cook,F. Christopher Zusi,Matthew D. Hill,Haiquan Fang,Bradley C. Pearce,Hyunsoo Park,(unknown),Ivar M. McDonald,Linda J. Bristow,John E. Macor,Richard E. Olson	3
3	Identification of Small Molecules That Selectively Inhibit Diacylglycerol Lipase–α Activity 2013 ·SLAS DISCOVERY ·(unknown),Yuval Blat,Barbara Robertson,Bradley C. Pearce,Donna L. Pedicord,Robert G. Gentles,Xuan‐Chuan Yu,Faika Mseeh,Nghi Nguyen,Jonathan C. Swaffield,David Harden,Ryan S. Westphal,Martyn Banks,Jonathan C. O’Connell	15
4	Molecular characterization and identification of surrogate substrates for diacylglycerol lipase α 2011 ·Biochemical and Biophysical Research Communications ·Donna L. Pedicord,Michael Flynn,(unknown),(unknown),Lisa Hunihan,Barbara Robertson,Bradley C. Pearce,Xuan‐Chuan Yu,Ryan S. Westphal,Yuval Blat	22
5	Inhibitors of HIV-1 attachment. Part 3: A preliminary survey of the effect of structural variation of the benzamide moiety on antiviral activity 2009 ·Bioorganic & Medicinal Chemistry Letters ·Nicholas A. Meanwell,Owen B. Wallace,(unknown),Milind Deshpande,Bradley C. Pearce,Ashok K. Trehan,(unknown),Zhilei Qiu,John J. Wright,(unknown),Yi-Fei Gong,(unknown),Wade Blair,Pei‐Yong Shi,Pin‐Fang Lin	34
6	E-Novo: An Automated Workflow for Efficient Structure-Based Lead Optimization 2009 ·Journal of Chemical Information and Modeling ·Bradley C. Pearce,David R. Langley,Jia Kang,Hongwei Huang,Amit Kulkarni	32
7	Respiratory syncytial virus fusion inhibitors. Part 6: An examination of the effect of structural variation of the benzimidazol-2-one heterocycle moiety 2007 ·Bioorganic & Medicinal Chemistry Letters ·Keith D. Combrink,H. Belgin Gülgeze,Jan Willem Thuring,Kuo‐Long Yu,Rita L. Civiello,Yi Zhang,Bradley C. Pearce,Zhiwei Yin,David R. Langley,Kathleen F. Kadow,Christopher Cianci,Zhufang Li,(unknown),Eugene V. Genovesi,Ivette Medina,Lucinda Lamb,Zheng Yang,Lisa Zadjura,Mark Krystal,Nicholas A. Meanwell	31
8	Respiratory syncytial virus fusion inhibitors. Part 3: Water-soluble benzimidazol-2-one derivatives with antiviral activity in vivo 2005 ·Bioorganic & Medicinal Chemistry Letters ·Kuo‐Long Yu,(unknown),Rita L. Civiello,Ashok K. Trehan,Bradley C. Pearce,Zhiwei Yin,Keith D. Combrink,H. Belgin Gülgeze,Yi Zhang,Kathleen F. Kadow,Christopher Cianci,(unknown),Eugene V. Genovesi,Ivette Medina,Lucinda Lamb,Philip R. Wyde,Mark Krystal,Nicholas A. Meanwell	31
9	Respiratory syncytial virus inhibitors. Part 2: Benzimidazol-2-one derivatives 2004 ·Bioorganic & Medicinal Chemistry Letters ·Kuo‐Long Yu,Yi Zhang,Rita L. Civiello,Ashok K. Trehan,Bradley C. Pearce,Zhiwei Yin,Keith D. Combrink,H. Belgin Gülgeze,(unknown),Kathleen F. Kadow,Christopher Cianci,Mark Krystal,Nicholas A. Meanwell	24
10	Salicylamide inhibitors of influenza virus fusion 2000 ·Bioorganic & Medicinal Chemistry Letters ·Keith D. Combrink,H. Belgin Gülgeze,Kuo‐Long Yu,Bradley C. Pearce,Ashok K. Trehan,Jianmei Wei,Milind Deshpande,Mark Krystal,Albert Torri,Guangxiang Luo,Christopher Cianci,(unknown),Laurence Tiley,Nicholas A. Meanwell	17
11	Stereoselective reduction via lithium borotritide: synthesis of3H-labeled 2-hydroxy-N-[(5-hydroxy-[5-3H]-1,3,3-trimethylcyclohexyl)methyl]-5-methylbenzamide 1999 ·Journal of Labelled Compounds and Radiopharmaceuticals ·Douglas D. Dischino,Nicholas A. Meanwell,Hiromi Morimoto,Bradley C. Pearce,(unknown),Albert Torri,Philip G. Williams,Kuo‐Long Yu	1
12	Structure Determination of the Products from the Acid-Catalyzed Condensation of Indole with Acetone 1996 ·The Journal of Organic Chemistry ·Wayland E. Noland,Michael J. Konkel,(unknown),Bradley C. Pearce,Charles L. Barnes,E. O. Schlemper	7
13	Dietary α-Tocopherol Attenuates the Impact of γ-Tocotrienol on Hepatic 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity in Chickens 1996 ·Journal of Nutrition ·Asaf A. Qureshi,Bradley C. Pearce,(unknown),A. Gapor,David M. Peterson,Charles E. Elson	133
14	Response of hypercholesterolemic subjects to administration of tocotrienols 1995 ·Lipids ·Asaf A. Qureshi,Basil A. Bradlow,Larry D. Brace,Jeanne M. Manganello,David M. Peterson,Bradley C. Pearce,J. J. Wright,A. Gapor,Charles E. Elson	159
15	Inhibitors of Cholesterol Biosynthesis. 2. Hypocholesterolemic and Antioxidant Activities of Benzopyran and Tetrahydronaphthalene Analogs of the Tocotrienols 1994 ·Journal of Medicinal Chemistry ·Bradley C. Pearce,Richard Parker,(unknown),Douglas D. Dischino,Elizabeth Gillespie,Asaf A. Qureshi,James R. Wright,(unknown)	111
16	ChemInform Abstract: Inhibitors of Cholesterol Biosynthesis. Part 2. Hypocholesterolemic and Antioxidant Activities of Benzopyran and Tetrahydronaphthalene Analogues of the Tocotrienols. 1994 ·ChemInform ·Bradley C. Pearce,Richard Parker,(unknown),Douglas D. Dischino,Elizabeth Gillespie,Asaf A. Qureshi,(unknown),J. J. Wright	19
17	Inhibitors of blood platelet cAMP phosphodiesterase. 2. Structure-activity relationships associated with 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones substituted with functionalized side chains 1992 ·Journal of Medicinal Chemistry ·Nicholas A. Meanwell,Bradley C. Pearce,(unknown),Edward C. Smith,(unknown),J. J. Wright,(unknown),(unknown),(unknown)	11
18	Hypocholesterolemic activity of synthetic and natural tocotrienols. 1992 ·Journal of Medicinal Chemistry ·Bradley C. Pearce,Rex A. Parker,(unknown),Asaf A. Qureshi,J. J. Wright	216
19	3-(3-Pyrrolyl)thiopyrrolidones as precursors of benzo[1,2-b:4,3-b']dipyrroles. Synthesis of structures related to the phosphodiesterase inhibitors PDE-I and PDE-II 1985 ·The Journal of Organic Chemistry ·Richard J. Sundberg,Bradley C. Pearce	25
20	A total synthesis of ()-anhydrocannabisativine. 1985 ·Tetrahedron Letters ·Harry H. Wasserman,Bradley C. Pearce	6

About Bradley C. Pearce

Bradley C. Pearce is a scholar working on Biochemistry, Virology and Organic Chemistry, having authored 33 papers that have together received 1.5k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (5 papers), Cholesterol and Lipid Metabolism (4 papers) and Synthesis and Biological Evaluation (4 papers). The work is most often cited by research in Biochemistry (614 citations), Nutrition and Dietetics (373 citations) and Organic Chemistry (451 citations). Bradley C. Pearce has collaborated with scholars based in United States, Germany and Malaysia. Frequent co-authors include J. J. Wright, Asaf A. Qureshi, David A. Gordon, R.A. Parker, Rex A. Parker, Charles E. Elson, A. Gapor, David M. Peterson, Nicholas A. Meanwell and Basil A. Bradlow. Their work appears in journals such as Journal of Biological Chemistry, Biochemical and Biophysical Research Communications and Journal of Medicinal Chemistry.

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