Bob D. Brown

1.9k citations

32 papers · 1.5k indexed · h-index 17

Co-authors: Richard M. Harland Ali Hemmati‐Brivanlou Hazel Sive Dale Frank Hans‐Georg Eichler Markus K. Müller Hubert Pehamberger Hermine Schlagbauer‐Wadl
Topics: RNA Interference and Gene Delivery (11 papers)Cell death mechanisms and regulation (5 papers)Advanced biosensing and bioanalysis techniques (5 papers)
Cited by: Molecular Biology Oncology Cancer Research
Journals: Nature Medicine Journal of Clinical Oncology Development
Partner nations: United States Spain Australia

In The Last Decade

Bob D. Brown

32 papers receiving 1.4k citations

Peers

Countries citing papers authored by Bob D. Brown

Since Specialization

Citations

This map shows the geographic impact of Bob D. Brown's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bob D. Brown with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bob D. Brown more than expected).

Fields of papers citing papers by Bob D. Brown

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bob D. Brown. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bob D. Brown. The network helps show where Bob D. Brown may publish in the future.

Co-authorship network of co-authors of Bob D. Brown

This figure shows the co-authorship network connecting the top 25 collaborators of Bob D. Brown. A scholar is included among the top collaborators of Bob D. Brown based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Bob D. Brown. Bob D. Brown is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	RNAi mediated silencing of STAT3/PD-L1 in tumor-associated immune cells induces robust anti-tumor effects in immunotherapy resistant tumors 2024 ·Molecular Therapy ·Shanthi Ganesh,(unknown),(unknown),(unknown),(unknown),Amy Mahan,(unknown),(unknown),(unknown),(unknown),Ilia Korboukh,(unknown),Laura Sanftner,René Rijnbrand,(unknown),Bob D. Brown	16
2	First-in-human randomized study of RNAi therapeutic RG6346 for chronic hepatitis B virus infection 2023 ·Journal of Hepatology ·Edward Gane,Won Kim,Tien Huey Lim,Pisit Tangkijvanich,Jung‐Hwan Yoon,William Sievert,Wattana Sukeepaisarnjaroen,Alexander Thompson,Vedran Pavlovic,(unknown),Cynthia Wat,Bob D. Brown,Hardean E. Achneck,Man‐Fung Yuen	25
3	Hepatic Lactate Dehydrogenase A: An RNA Interference Target for the Treatment of All Known Types of Primary Hyperoxaluria 2021 ·Kidney International Reports ·Gema Ariceta,Kelly Barrios,Bob D. Brown,Bernd Höppe,R. Roßkamp,Craig B. Langman	30
4	Specific Inhibition of Hepatic Lactate Dehydrogenase Reduces Oxalate Production in Mouse Models of Primary Hyperoxaluria 2018 ·Molecular Therapy ·Cheng-Jung Lai,(unknown),Jessica J. Gierut,Utsav Saxena,Wei Zhou,Michael Dills,Rohan Diwanji,Chaitali Dutta,Martin L. Koser,Naim Nazef,(unknown),Bo Young Kim,Cristina Martín-Higueras,Eduardo Salido,Weimin Wang,Marc Abrams,Henryk Dudek,Bob D. Brown	83
5	RNAi-Mediated β-Catenin Inhibition Promotes T Cell Infiltration and Antitumor Activity in Combination with Immune Checkpoint Blockade 2018 ·Molecular Therapy ·Shanthi Ganesh,(unknown),(unknown),Jihye Park,Weimin Wang,Bob D. Brown,Marc Abrams	88
6	Inhibition of Glycogen Synthase II with RNAi Prevents Liver Injury in Mouse Models of Glycogen Storage Diseases 2018 ·Molecular Therapy ·(unknown),Jessica J. Gierut,Wei Zhou,Michael Dills,Rohan Diwanji,Monika Gjorgjieva,Utsav Saxena,Jr-Shiuan Yang,(unknown),(unknown),(unknown),Bo Young Kim,Weimin Wang,Marc Abrams,(unknown),Gilles Mithieux,Fabienne Rajas,Henryk Dudek,Bob D. Brown,Cheng-Jung Lai	22
7	Abstract B03: RNAi-mediated β-catenin inhibition sensitizes noninflamed tumors to immune checkpoint blockade 2018 ·Cancer Immunology Research ·Shanthi Ganesh,(unknown),Weimin Wang,Bob D. Brown,Marc Abrams	1
8	β-Catenin mRNA Silencing and MEK Inhibition Display Synergistic Efficacy in Preclinical Tumor Models 2017 ·Molecular Cancer Therapeutics ·Shanthi Ganesh,(unknown),(unknown),Martin L. Koser,(unknown),(unknown),Cheng-Jung Lai,Henryk Dudek,Weimin Wang,Bob D. Brown,Marc Abrams	18
9	Direct Pharmacological Inhibition of β-Catenin by RNA Interference in Tumors of Diverse Origin 2016 ·Molecular Cancer Therapeutics ·Shanthi Ganesh,Martin L. Koser,(unknown),(unknown),Junyan Tao,(unknown),Bo Ying,Dongyu Chen,(unknown),Edmond Chipumuro,Zakir Siddiquee,(unknown),Cheng-Jung Lai,Henryk Dudek,Satdarshan P. Monga,Weimin Wang,Bob D. Brown,Marc Abrams	50
10	Safety and activity of DCR-MYC, a first-in-class Dicer-substrate small interfering RNA (DsiRNA) targeting MYC, in a phase I study in patients with advanced solid tumors. 2015 ·Journal of Clinical Oncology ·Anthony W. Tolcher,Kyriakos P. Papadopoulos,Amita Patnaik,Drew Rasco,(unknown),Debra L. Wood,(unknown),Manish Sharma,Linda Janisch,Bob D. Brown,Pankaj Bhargava,Mark J. Ratain	96
11	Glutathione and Bcl-2 targeting facilitates elimination by chemoradiotherapy of human A375 melanoma xenografts overexpressing bcl-xl, bcl-2, and mcl-1 2012 ·Journal of Translational Medicine ·Salvador Mena,María L. Rodríguez,Ángel Ortega,(unknown),Elena Obrador,Miguel Asensi,(unknown),Miguel Jover Cerdá,Bob D. Brown,José M. Estrela	11
12	Quantitative Analysis of Dicer Substrate Oligonucleotides in Mouse Liver by Ultra-High-Performance Liquid Chromatography–Electrospray Ionization Tandem Mass Spectrometry 2011 ·Assay and Drug Development Technologies ·(unknown),(unknown),Sujit K. Basu,Shuhao Zhu,Bob D. Brown,Roberto Guerciolini,Douglas M. Fambrough	10
13	Downregulation of BCL-2 Induces Downregulation of Carbonic Anhydrase IX, Vascular Endothelial Growth Factor, and pAkt and Induces Radiation Sensitization 2007 ·Urology ·Satoshi Anai,Kathleen T. Shiverick,(unknown),Kogenta Nakamura,Steve Goodison,Bob D. Brown,Charles J. Rosser	19
14	Irradiation of Human Prostate Cancer Cells Increases Uptake of Antisense Oligodeoxynucleotide 2007 ·International Journal of Radiation OncologyBiologyPhysics ·Satoshi Anai,Bob D. Brown,Kogenta Nakamura,Steve Goodison,Yoshihiko Hirao,Charles J. Rosser	7
15	Knock-down of Bcl-2 by antisense oligodeoxynucleotides induces radiosensitization and inhibition of angiogenesis in human PC-3 prostate tumor xenografts 2007 ·Molecular Cancer Therapeutics ·Satoshi Anai,Steve Goodison,Kathleen T. Shiverick,Yoshihiko Hirao,Bob D. Brown,Charles J. Rosser	51
16	Comparison of D-G3139 and Its Enantiomer L-G3139 in Melanoma Cells Demonstrates Minimal In Vitro but Dramatic In Vivo Chiral Dependency 2007 ·Molecular Therapy ·Johnathan C. Lai,Bob D. Brown,(unknown),Stefan Vonhoff,(unknown),Wenzhi Tan,Marco Colombini,Risini D. Weeratna,Paul S. Miller,Luba Benimetskaya,Cy A. Stein	7
17	Brief intravenous infusions of oblimersen (Genasense; Bcl-2 antisense) alone and in combination with multiple agents are highly effective in human tumor xenografts 2007 ·Journal of Clinical Oncology ·Bob D. Brown,(unknown),(unknown),R P Warrell	1
18	bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice 1998 ·Nature Medicine ·Burkhard Jansen,Hermine Schlagbauer‐Wadl,Bob D. Brown,Robert N. Bryan,Andrea van Elsas,Markus K. Müller,Klaus Wolff,Hans‐Georg Eichler,Hubert Pehamberger	410
19	Description of the Intrafollicular Delivery of Large Molecular Weight Molecules to Follicles of Human Scalp Skin In Vitro 1997 ·Journal of Pharmaceutical Sciences ·Linda M. Lieb,(unknown),R. Nick Bryan,Bob D. Brown,Gerald G. Krueger	38
20	Evidence for simultaneous derepression of messenger RNA and the guanine nucleotide exchange factor in fertilized sea urchin eggs 1987 ·Developmental Biology ·(unknown),Bob D. Brown,J N Dholakia,Charles L. Woodley,Albert J. Wahba,Merrill B. Hille	30

About Bob D. Brown

Bob D. Brown is a scholar working on Biotechnology, Cancer Research and Oncology, having authored 32 papers that have together received 1.5k indexed citations. Recurring topics across this work include RNA Interference and Gene Delivery (11 papers), Cell death mechanisms and regulation (5 papers) and Advanced biosensing and bioanalysis techniques (5 papers). The work is most often cited by research in Molecular Biology (1.1k citations), Oncology (321 citations) and Cancer Research (160 citations). Bob D. Brown has collaborated with scholars based in United States, Spain and Australia. Frequent co-authors include Richard M. Harland, Ali Hemmati‐Brivanlou, Hazel Sive, Dale Frank, Hans‐Georg Eichler, Markus K. Müller, Hubert Pehamberger, Hermine Schlagbauer‐Wadl, Robert N. Bryan and Klaus Wolff. Their work appears in journals such as Nature Medicine, Journal of Clinical Oncology and Development.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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