Blake Wiedenheft

11.5k total citations · 7 hit papers
82 papers, 8.1k citations indexed

About

Blake Wiedenheft is a scholar working on Molecular Biology, Ecology and Genetics. According to data from OpenAlex, Blake Wiedenheft has authored 82 papers receiving a total of 8.1k indexed citations (citations by other indexed papers that have themselves been cited), including 67 papers in Molecular Biology, 25 papers in Ecology and 19 papers in Genetics. Recurrent topics in Blake Wiedenheft's work include CRISPR and Genetic Engineering (52 papers), Bacteriophages and microbial interactions (24 papers) and RNA and protein synthesis mechanisms (22 papers). Blake Wiedenheft is often cited by papers focused on CRISPR and Genetic Engineering (52 papers), Bacteriophages and microbial interactions (24 papers) and RNA and protein synthesis mechanisms (22 papers). Blake Wiedenheft collaborates with scholars based in United States, Netherlands and United Kingdom. Blake Wiedenheft's co-authors include Jennifer A. Doudna, Samuel H. Sternberg, Ryan N. Jackson, Kaihong Zhou, John van der Oost, Edze R. Westra, C. Martin Lawrence, Rotem Sorek, Martin Jínek and Royce A. Wilkinson and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Blake Wiedenheft

79 papers receiving 8.0k citations

Hit Papers

RNA-guided genetic silencing systems in bacteria and archaea 2010 2026 2015 2020 2012 2014 2010 2013 2011 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. RNA-guided genetic silencing systems in bacteria and archaea
    2012 1.4k citations Blake Wiedenheft, Samuel H. Sternberg et al. Nature profile →
  2. Unravelling the structural and mechanistic basis of CRISPR–Cas systems
    2014 545 citations John van der Oost, Edze R. Westra et al. profile →
  3. Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease
    2010 531 citations R.E. Haurwitz, Martin Jínek et al. Science profile →
  4. CRISPR-Mediated Adaptive Immune Systems in Bacteria and Archaea
    2013 479 citations C. Martin Lawrence, Blake Wiedenheft et al. profile →
  5. Structural basis for CRISPR RNA-guided DNA recognition by Cascade
    2011 447 citations Esther van Duijn, Jelle B. Bultema et al. Nature Structural & Molecular Biology profile →
  6. RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions
    2011 350 citations Blake Wiedenheft, Esther van Duijn et al. Proceedings of the National Academy of Sciences profile →
  7. Structures of the RNA-guided surveillance complex from a bacterial immune system
    2011 306 citations Blake Wiedenheft, Gabriel C. Lander et al. Nature profile →

Peers

Blake Wiedenheft
Dennis Romero United States
Francisco J. M. Mojica Spain
Edze R. Westra United Kingdom
Virginijus Šikšnys Lithuania
Matthijs M. Jore Netherlands
Karen L. Maxwell Canada
Roger A. Garrett Denmark
Philippe Horvath United States
Michael P. Terns United States
Patrick Essletzbichler Austria
Dennis Romero United States
Blake Wiedenheft
Citations per year, relative to Blake Wiedenheft Blake Wiedenheft (= 1×) peers Dennis Romero

Countries citing papers authored by Blake Wiedenheft

Since Specialization
Citations

This map shows the geographic impact of Blake Wiedenheft's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Blake Wiedenheft with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Blake Wiedenheft more than expected).

Fields of papers citing papers by Blake Wiedenheft

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Blake Wiedenheft. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Blake Wiedenheft. The network helps show where Blake Wiedenheft may publish in the future.

Co-authorship network of co-authors of Blake Wiedenheft

This figure shows the co-authorship network connecting the top 25 collaborators of Blake Wiedenheft. A scholar is included among the top collaborators of Blake Wiedenheft based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Blake Wiedenheft. Blake Wiedenheft is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Brodie, Jedediah F., Blake Wiedenheft, Ronald Sandler, et al.. (2025). Synthetically Assisted Conservation and the Application of Emerging Biological Technologies for the Protection of Biodiversity. Conservation Letters. 18(3).
2.
Tang, Stephen, Rimantė Žedaveinytė, Javier Mancilla-Ramı́rez, et al.. (2025). Protein-primed homopolymer synthesis by an antiviral reverse transcriptase. Nature. 643(8074). 1352–1362.
3.
Buyukyoruk, Murat, et al.. (2025). Discovery of Diverse CRISPR Leader Motifs, Putative Functions, and Applications for Enhanced CRISPR Detection and Subtype Annotation. The CRISPR Journal. 8(2). 137–148. 3 indexed citations
4.
Nemudryi, Artem, DeAnna C. Bublitz, Margie Kinnersley, et al.. (2023). Polyamines and linear DNA mediate bacterial threat assessment of bacteriophage infection. Proceedings of the National Academy of Sciences. 120(9). e2216430120–e2216430120. 16 indexed citations
5.
Santiago‐Frangos, Andrew, Tanner Wiegand, Murat Buyukyoruk, et al.. (2023). Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays. Nature Structural & Molecular Biology. 30(11). 1675–1685. 6 indexed citations
6.
Wiegand, Tanner, et al.. (2023). Functional and Phylogenetic Diversity of Cas10 Proteins. The CRISPR Journal. 6(2). 152–162. 11 indexed citations
7.
Buyukyoruk, Murat, et al.. (2023). Clarifying CRISPR: Why Repeats Identified in the Human Genome Should Not Be Considered CRISPRs. The CRISPR Journal. 6(3). 216–221. 2 indexed citations
8.
Wiegand, Tanner, Artem Nemudryi, Anna Nemudraia, et al.. (2022). The Rise and Fall of SARS-CoV-2 Variants and Ongoing Diversification of Omicron. Viruses. 14(9). 2009–2009. 18 indexed citations
9.
Nemudraia, Anna, Artem Nemudryi, Murat Buyukyoruk, et al.. (2022). Sequence-specific capture and concentration of viral RNA by type III CRISPR system enhances diagnostic. Nature Communications. 13(1). 7762–7762. 12 indexed citations
10.
Nemudraia, Anna, Artem Nemudryi, Jodi F. Hedges, et al.. (2022). Severe Acute Respiratory Syndrome Coronavirus 2 Is Detected in the Gastrointestinal Tract of Asymptomatic Endoscopy Patients but Is Unlikely to Pose a Significant Risk to Healthcare Personnel. SHILAP Revista de lepidopterología. 1(5). 844–852. 5 indexed citations
11.
Daughenbaugh, Katie F., Charles C. Carey, Alexander J. McMenamin, et al.. (2021). Metatranscriptome Analysis of Sympatric Bee Species Identifies Bee Virus Variants and a New Virus, Andrena-Associated Bee Virus-1. Viruses. 13(2). 291–291. 20 indexed citations
12.
Santiago‐Frangos, Andrew, et al.. (2021). Distribution and phasing of sequence motifs that facilitate CRISPR adaptation. Current Biology. 31(16). 3515–3524.e6. 16 indexed citations
13.
Nemudryi, Artem, Anna Nemudraia, Tanner Wiegand, et al.. (2020). Temporal Detection and Phylogenetic Assessment of SARS-CoV-2 in Municipal Wastewater. Cell Reports Medicine. 1(6). 100098–100098. 364 indexed citations
14.
Fang, Fang, Meena Sukhwani, Zhengyuan Wang, et al.. (2018). A PAX5–OCT4–PRDM1 developmental switch specifies human primordial germ cells. Nature Cell Biology. 20(6). 655–665. 31 indexed citations
15.
Redding, Sy, Samuel H. Sternberg, Bryan Gibb, et al.. (2015). Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System. Cell. 163(4). 854–865. 148 indexed citations
16.
Jackson, Ryan N., Sarah Golden, Joshua Carter, et al.. (2014). Crystal structure of the CRISPR RNA–guided surveillance complex from Escherichia coli. Science. 345(6203). 1473–1479. 201 indexed citations
17.
Wiedenheft, Blake, Esther van Duijn, Jelle B. Bultema, et al.. (2011). RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions. Proceedings of the National Academy of Sciences. 108(25). 10092–10097. 350 indexed citations breakdown →
18.
Haurwitz, R.E., Martin Jínek, Blake Wiedenheft, Kaihong Zhou, & Jennifer A. Doudna. (2010). Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease. Science. 329(5997). 1355–1358. 531 indexed citations breakdown →
19.
Snyder, Jamie C., Blake Wiedenheft, Matt Lavin, et al.. (2007). Virus movement maintains local virus population diversity. Proceedings of the National Academy of Sciences. 104(48). 19102–19107. 55 indexed citations
20.
Wiedenheft, Blake, Mark Allen, George H. Gauss, et al.. (2006). Dps-like protein from the hyperthermophilic archaeon Pyrococcus furiosus. Journal of Inorganic Biochemistry. 100(5-6). 1061–1068. 42 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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