Antonı́n Holý

15.0k total citations · 2 hit papers
587 papers, 12.5k citations indexed

About

Antonı́n Holý is a scholar working on Molecular Biology, Organic Chemistry and Infectious Diseases. According to data from OpenAlex, Antonı́n Holý has authored 587 papers receiving a total of 12.5k indexed citations (citations by other indexed papers that have themselves been cited), including 352 papers in Molecular Biology, 242 papers in Organic Chemistry and 200 papers in Infectious Diseases. Recurrent topics in Antonı́n Holý's work include HIV/AIDS drug development and treatment (197 papers), Biochemical and Molecular Research (185 papers) and DNA and Nucleic Acid Chemistry (119 papers). Antonı́n Holý is often cited by papers focused on HIV/AIDS drug development and treatment (197 papers), Biochemical and Molecular Research (185 papers) and DNA and Nucleic Acid Chemistry (119 papers). Antonı́n Holý collaborates with scholars based in Czechia, Belgium and Switzerland. Antonı́n Holý's co-authors include Erik De Clercq, Ivan Rosenberg, Ivan Votruba, Jan Balzarini, Milena Masojı́dková, Hana Dvořáková, Robert Snoeck, Takashi Sakuma, Lieve Naesens and Graciela Andreï and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Antonı́n Holý

574 papers receiving 11.9k citations

Hit Papers

A novel selective broad-s... 1986 2026 1999 2012 1986 2005 200 400 600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. A novel selective broad-spectrum anti-DNA virus agent
    1986 649 citations Erik De Clercq, Antonı́n Holý et al. Nature profile →
  2. Acyclic nucleoside phosphonates: a key class of antiviral drugs
    2005 559 citations Erik De Clercq, Antonı́n Holý profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Antonı́n Holý 5.9k 5.3k 4.6k 3.6k 1.9k 587 12.5k
Piet Herdewijn 12.5k 2.1× 6.0k 1.1× 2.9k 0.6× 5.2k 1.4× 2.9k 1.5× 787 19.5k
Graciela Andreï 4.1k 0.7× 3.0k 0.6× 4.7k 1.0× 4.6k 1.3× 1.6k 0.9× 509 13.0k
Robert Snoeck 5.0k 0.9× 4.8k 0.9× 6.5k 1.4× 5.5k 1.5× 3.0k 1.6× 556 17.3k
Lieve Naesens 3.2k 0.5× 3.5k 0.7× 4.4k 1.0× 2.2k 0.6× 1.3k 0.7× 284 9.6k
Jan Balzarini 4.4k 0.7× 2.7k 0.5× 1.7k 0.4× 5.7k 1.6× 1.5k 0.8× 515 11.7k
Masanori Baba 5.0k 0.9× 6.9k 1.3× 3.3k 0.7× 3.6k 1.0× 5.9k 3.1× 372 16.0k
Gertrude B. Elion 5.4k 0.9× 2.0k 0.4× 5.0k 1.1× 1.5k 0.4× 426 0.2× 176 13.0k
Jan Balzarini 3.8k 0.6× 2.2k 0.4× 1.4k 0.3× 2.7k 0.7× 1.2k 0.6× 213 7.6k
Rudi Pauwels 4.4k 0.7× 9.2k 1.7× 3.4k 0.7× 2.8k 0.8× 8.1k 4.2× 145 14.9k
Samuel Broder 3.0k 0.5× 5.8k 1.1× 2.8k 0.6× 1.1k 0.3× 5.1k 2.7× 121 12.3k

Countries citing papers authored by Antonı́n Holý

Since Specialization
Citations

This map shows the geographic impact of Antonı́n Holý's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Antonı́n Holý with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Antonı́n Holý more than expected).

Fields of papers citing papers by Antonı́n Holý

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Antonı́n Holý. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Antonı́n Holý. The network helps show where Antonı́n Holý may publish in the future.

Co-authorship network of co-authors of Antonı́n Holý

This figure shows the co-authorship network connecting the top 25 collaborators of Antonı́n Holý. A scholar is included among the top collaborators of Antonı́n Holý based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Antonı́n Holý. Antonı́n Holý is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Holý, Antonı́n, et al.. (2015). Influence of Acyclic Nucleoside Phosphonate Antivirals on Gene Expression of Chemokine Receptors CCR5 and CXCR4. Folia Biologica. 61(1). 1–7. 2 indexed citations
2.
Balzarini, Jan, Graciela Andreï, E Balestra, et al.. (2013). A Multi-targeted Drug Candidate with Dual Anti-HIV and Anti-HSV Activity. PLoS Pathogens. 9(7). e1003456–e1003456. 20 indexed citations
3.
Janeba, Zlatko, Antonı́n Holý, Radek Pohl, et al.. (2010). Synthesis and biological evaluation of acyclic nucleotide analogues with a furo[2,3- d ]pyrimidin-2(3 H )-one base. Canadian Journal of Chemistry. 88(7). 628–638. 15 indexed citations
4.
Naesens, Lieve, Graciela Andreï, Ivan Votruba, et al.. (2008). Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine. Biochemical Pharmacology. 76(8). 997–1005. 20 indexed citations
5.
6.
7.
Renders, Marleen, et al.. (2007). Enzymatic Synthesis of Phosphonomethyl Oligonucleotides by Therminator Polymerase. Angewandte Chemie International Edition. 46(14). 2501–2504. 19 indexed citations
8.
Nekvindová, Jana, et al.. (2006). Experimental approaches to studies on drug metabolism and drug interactions in man: interaction of acyclic nucleoside phosphonates with human liver cytochromes P450 and flavin-containing monooxygenase 3.. PubMed. 27 Suppl 2. 27–30. 4 indexed citations
9.
Kmonı́čková, Eva, et al.. (2006). Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine. European Journal of Pharmacology. 530(1-2). 179–187. 16 indexed citations
10.
Stittelaar, Koert J., Johan Neyts, Lieve Naesens, et al.. (2005). Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection. Nature. 439(7077). 745–748. 166 indexed citations
11.
Jacobson, Kenneth A., M. Ohno, Heng T. Duong, et al.. (2005). A Neoceptor Approach to Unraveling Microscopic Interactions between the Human A2A Adenosine Receptor and Its Agonists. Chemistry & Biology. 12(2). 237–247. 37 indexed citations
12.
Zı́dek, Zdeňek, Eva Kmonı́čková, & Antonı́n Holý. (2005). CYTOTOXICITY OF PIVOXIL ESTERS OF ANTIVIRAL ACYCLIC NUCLEOSIDE PHOSPHONATES: ADEFOVIR DIPIVOXIL VERSUS ADEFOVIR. Biomedical Papers. 149(2). 315–319. 11 indexed citations
13.
Birkuš, Gabriel, Dominik Rejman, Miroslav Otmar, et al.. (2004). The Substrate Activity of (S)-9-[3-Hydroxy-(2-phosphonomethoxy)Propyl]Adenine Diphosphate toward DNA Polymerases α, δ and ε. Antiviral chemistry & chemotherapy. 15(1). 23–33. 6 indexed citations
14.
Holý, Antonı́n. (2003). Phosphonomethoxyalkyl Analogs of Nucleotides. Current Pharmaceutical Design. 9(31). 2567–2592. 179 indexed citations
15.
16.
Kramata, Pavel, Ivan Votruba, B Otová, & Antonı́n Holý. (1996). Different inhibitory potencies of acyclic phosphonomethoxyalkyl nucleotide analogs toward DNA polymerases alpha, delta and epsilon.. Molecular Pharmacology. 49(6). 1005–1011. 102 indexed citations
17.
Vonka, Vladimı́r, et al.. (1990). Properties of a 9-(2-phosphonylmethoxyethyl)adenine (PMEA)-resistant herpes simplex virus type 1 virus mutant. Antiviral Research. 14(2). 117–121. 13 indexed citations
18.
Schuster, Gottfried & Antonı́n Holý. (1988). Inhibitory effects of 9-(2,3-dihydroxypropyl) adenine and 3-(adenin-9-yl)-2-hydroxypropanoic acid 2-methylpropylester on potato virus X replication. Antiviral Research. 9(5). 329–334. 4 indexed citations
19.
Holý, Antonı́n. (1984). Preparation and synthetic utilization of 3-(adenin-9-yl)-2-hydroxyalkanoic acids and their derivatives. Collection of Czechoslovak Chemical Communications. 49(9). 2148–2166. 14 indexed citations
20.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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