Malcolm J. Sheardown

4.9k total citations · 1 hit paper
82 papers, 4.1k citations indexed

About

Malcolm J. Sheardown is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Physiology. According to data from OpenAlex, Malcolm J. Sheardown has authored 82 papers receiving a total of 4.1k indexed citations (citations by other indexed papers that have themselves been cited), including 66 papers in Molecular Biology, 53 papers in Cellular and Molecular Neuroscience and 10 papers in Physiology. Recurrent topics in Malcolm J. Sheardown's work include Neuroscience and Neuropharmacology Research (40 papers), Receptor Mechanisms and Signaling (40 papers) and Ion channel regulation and function (15 papers). Malcolm J. Sheardown is often cited by papers focused on Neuroscience and Neuropharmacology Research (40 papers), Receptor Mechanisms and Signaling (40 papers) and Ion channel regulation and function (15 papers). Malcolm J. Sheardown collaborates with scholars based in Denmark, United States and United Kingdom. Malcolm J. Sheardown's co-authors include Tage Honoré, Poul Jacobsen, Anker Jón Hansen, Elsebet Ø. Nielsen, Peter D. Suzdak, Per Sauerberg, Harukuni Ikeda, Preben H. Olesen, Charles H. Mitch and Lars Nordholm and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and The Journal of Physiology.

In The Last Decade

Malcolm J. Sheardown

80 papers receiving 3.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

1990 961 citations Malcolm J. Sheardown, Elsebet Ø. Nielsen et al. Science profile →

Peers

Countries citing papers authored by Malcolm J. Sheardown

Since Specialization

Citations

This map shows the geographic impact of Malcolm J. Sheardown's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Malcolm J. Sheardown with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Malcolm J. Sheardown more than expected).

Fields of papers citing papers by Malcolm J. Sheardown

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Malcolm J. Sheardown. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Malcolm J. Sheardown. The network helps show where Malcolm J. Sheardown may publish in the future.

Co-authorship network of co-authors of Malcolm J. Sheardown

This figure shows the co-authorship network connecting the top 25 collaborators of Malcolm J. Sheardown. A scholar is included among the top collaborators of Malcolm J. Sheardown based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Malcolm J. Sheardown. Malcolm J. Sheardown is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Agonist-induced functional desensitization of recombinant human 5-HT2 receptors expressed in CHO-K1 cells22Abbreviations: 5-HT, 5-hydroxytryptamine; CHO, Chinese hamster ovary; PI, phosphoinositide; FLIPR, fluorimetric imaging plate reader; mCPP, m-chlorophenylpiperazine; DOI, 2,5-dimethoxy-4-iodoamphetamine hydrobromide, GPCR, G-protein-coupled receptor; and PCR, polymerase chain reaction. 2001 ·Biochemical Pharmacology ·Richard H. Porter, (unknown), Nicola H. Allen, Helen Lamb, Dean F. Revell, Malcolm J. Sheardown	22
2	Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5R,6R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane 1998 ·European Journal of Pharmacology ·(unknown), Harlan E. Shannon, Kurt Rasmussen, Neil W. DeLapp, Charles H. Mitch, John S. Ward, David O. Calligaro, (unknown), Malcolm J. Sheardown, Preben H. Olesen, Michael D.B. Swedberg, Per Sauerberg, Anders Fink‐Jensen	53
3	Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects 1998 ·Brain Research ·Frank P. Bymaster, (unknown), Steven Peters, Wei Zhang, John S. Ward, Charles H. Mitch, David O. Calligaro, Celia A. Whitesitt, Neil W. DeLapp, Harlan E. Shannon, Karin Rimvall, Lone Jeppesen, Malcolm J. Sheardown, Anders Fink‐Jensen, Per Sauerberg	56
4	Muscarinic agonists exhibit functional dopamine antagonism in unilaterally 6-OHDA lesioned rats 1998 ·Neuroreport ·Anders Fink‐Jensen, Peter Lommer Kristensen, Harlan E. Shannon, David O. Calligaro, Neil W. DeLapp, (unknown), John S. Ward, C. Thomsen, (unknown), Malcolm J. Sheardown, Lone Jeppesen, Per Sauerberg, Frank P. Bymaster	22
5	Pharmacology of Butylthio[2.2.2] (LY297802/NNC11-1053): A Novel Analgesic with Mixed Muscarinic Receptor Agonist and Antagonist Activity 1997 ·Journal of Pharmacology and Experimental Therapeutics ·Harlan E. Shannon, Malcolm J. Sheardown, Frank P. Bymaster, David O. Calligaro, Neil W. DeLapp, J. S. Gidda, (unknown), Barry D. Sawyer, Peter W. Stengel, John S. Ward, David T. Wong, Preben H. Olesen, Peter D. Suzdak, Per Sauerberg, Michael D.B. Swedberg	22
6	The triggering of spreading depression in the chick retina by nicotinic receptor agonists 1997 ·European Journal of Pharmacology ·Malcolm J. Sheardown	8
7	Phenylglycines can Evoke Quisqualate‐primed Depolarizations in Rat Cingulate Cortex: An Effect Associated with [³H]DL‐AP₄ Uptake 1996 ·European Journal of Neuroscience ·Malcolm J. Sheardown, Christian Thomsen	7
8	(S)‐Carboxy‐3‐Hydroxyphenylglycine, an Antagonist of Metabotropic Glutamate Receptor (mGluR)1a and an Agonist of mGluR2, Protects Against Audiogenic Seizures in DBA/2 Mice 1994 ·Journal of Neurochemistry ·Christian Thomsen, Henrik Klitgaard, Malcolm J. Sheardown, Helen C. Jackson, (unknown), (unknown), Svend Treppendahl, Peter D. Suzdak	49
9	Pharmacological profile of a novel neuronal calcium channel blocker includes reduced cerebral damage and neurological deficits in rat focal ischemia 1994 ·Pharmacology Biochemistry and Behavior ·Frank C. Barone, William J. Price, Palle Jakobsen, Malcolm J. Sheardown, Giora Feuerstein	31
10	Cerebrovascular permeability and brain edema after cortical photochemical infarcts in the rat 1993 ·Acta Neuropathologica ·Henning Laursen, Anker Jón Hansen, Malcolm J. Sheardown	12
11	Characterization of the metabotropic glutamate receptor in mouse cerebellar granule cells: lack of effect of 2,3-dihydroxy-6-nitro-7-sulphamoylbenzo(F)-quinoxaline (NBQX) 1993 ·European Journal of Pharmacology Molecular Pharmacology ·Peter D. Suzdak, Malcolm J. Sheardown, Tage Honoré	11
12	AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h 1993 ·European Journal of Pharmacology ·Malcolm J. Sheardown, Peter D. Suzdak, Lars Nordholm	172
13	Metabotropic glutamate receptor agonists reduce epileptiform activity in the rat cortex 1992 ·Neuroreport ·Malcolm J. Sheardown	23
14	Novel functional M1 selective muscarinic agonists. Synthesis and structure-activity relationships of 3-(1,2,5-thiadiazolyl)-1,2,5,6-tetrahydro-1-methylpyridines 1992 ·Journal of Medicinal Chemistry ·Per Sauerberg, Preben H. Olesen, (unknown), Svend Treppendahl, Malcolm J. Sheardown, Tage Honoré, Charles H. Mitch, John S. Ward, Andrew Pike	131
15	Protection against ischemic hippocampal CAI damage in the rat with a new non-NMDA antagonist, NBQX 1992 ·Acta Neurologica Scandinavica ·Nils Henrik Diemer, Martin Balslev Jørgensen, Flemming Fryd Johansen, Malcolm J. Sheardown, T. Honoré	99
16	Muscarinic cholinergic agonists and antagonists of the 3-(3-alkyl-1,2,4-oxadiazol-5-yl)-1,2,5,6-tetrahydropyridine type. Synthesis and structure-activity relationships 1991 ·Journal of Medicinal Chemistry ·Per Sauerberg, (unknown), Lone Nielsen, Malcolm J. Sheardown, Tage Honoré	40
17	2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia breakdown → 1990 ·Science ·Malcolm J. Sheardown, Elsebet Ø. Nielsen, Anker Jón Hansen, Poul Jacobsen, Tage Honoré	961
18	A potent antagonist of the strychnine insensitive glycine receptor has anticonvulsant properties 1989 ·European Journal of Pharmacology ·Malcolm J. Sheardown, Jørgen Drejer, Leif H. Jensen, Carsten E. Stidsen, Tage Honoré	34
19	Glycine reverses the effect of HA-966 on NMDA responses in cultured rat cortical neurons and in chick retina 1989 ·Neuroscience Letters ·Jørgen Drejer, Malcolm J. Sheardown, Elsebet Ø. Nielsen, T. Honoré	24
20	A new and specific non-NMDA receptor antagonist, FG 9065, blocks L-AP4-evoked depolarization in rat cerebral cortex 1988 ·European Journal of Pharmacology ·Malcolm J. Sheardown	29

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