Alexander Wree

7.7k total citations · 5 hit papers
90 papers, 6.0k citations indexed

About

Alexander Wree is a scholar working on Epidemiology, Hepatology and Molecular Biology. According to data from OpenAlex, Alexander Wree has authored 90 papers receiving a total of 6.0k indexed citations (citations by other indexed papers that have themselves been cited), including 55 papers in Epidemiology, 36 papers in Hepatology and 24 papers in Molecular Biology. Recurrent topics in Alexander Wree's work include Liver Disease Diagnosis and Treatment (48 papers), Liver Disease and Transplantation (17 papers) and Inflammasome and immune disorders (16 papers). Alexander Wree is often cited by papers focused on Liver Disease Diagnosis and Treatment (48 papers), Liver Disease and Transplantation (17 papers) and Inflammasome and immune disorders (16 papers). Alexander Wree collaborates with scholars based in Germany, United States and Austria. Alexander Wree's co-authors include Ariel E. Feldstein, Hal M. Hoffman, Ali Canbay, Casey D. Johnson, Akiko Eguchi, Matthew D. McGeough, Carla A. Peña, María Eugenia Inzaugarat, Lori Broderick and Frank Tacke and has published in prestigious journals such as Journal of Clinical Investigation, Journal of Clinical Oncology and SHILAP Revista de lepidopterología.

In The Last Decade

Alexander Wree

82 papers receiving 5.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

2017 863 citations Auvro R. Mridha, Alexander Wree et al. Journal of Hepatology profile →
NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

2013 779 citations Alexander Wree, Akiko Eguchi et al. Hepatology profile →
From NAFLD to NASH to cirrhosis—new insights into disease mechanisms

2013 491 citations Alexander Wree, Ali Canbay et al. profile →
Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis

2020 405 citations Casey D. Johnson, Leon A. Adams et al. Journal of Hepatology profile →
NLRP3 inflammasome activation is required for fibrosis development in NAFLD

2014 404 citations Alexander Wree, María Eugenia Inzaugarat et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Alexander Wree Germany	35	3.5k	2.6k	1.5k	875	779	90	6.0k
Samuele De Minicis Italy	39	4.3k 1.2×	1.8k 0.7×	3.2k 2.1×	1.1k 1.2×	1.3k 1.7×	57	7.1k
Carmelo García‐Monzón Spain	36	2.9k 0.8×	1.2k 0.5×	1.5k 1.0×	781 0.9×	513 0.7×	102	4.6k
Makoto Nakamuta Japan	42	3.6k 1.0×	1.9k 0.7×	2.2k 1.5×	1.2k 1.4×	1.3k 1.7×	217	6.6k
Jacquelyn J. Maher United States	40	3.2k 0.9×	2.0k 0.8×	2.9k 1.9×	773 0.9×	1.3k 1.6×	97	6.8k
Takato Ueno Japan	40	2.6k 0.8×	1.7k 0.7×	2.2k 1.4×	1.1k 1.3×	836 1.1×	149	6.0k
Narci Teoh Australia	30	2.0k 0.6×	1.4k 0.5×	1.1k 0.7×	592 0.7×	955 1.2×	50	3.8k
Hironori Koga Japan	39	1.7k 0.5×	1.7k 0.6×	1.8k 1.2×	481 0.5×	762 1.0×	155	5.3k
Sumio Kawata Japan	45	2.0k 0.6×	1.8k 0.7×	1.8k 1.2×	673 0.8×	1.0k 1.3×	181	6.1k
Toshiji Saibara Japan	39	4.2k 1.2×	1.3k 0.5×	2.2k 1.4×	1.8k 2.0×	868 1.1×	169	6.4k
Mariana Verdelho Machado Portugal	36	4.9k 1.4×	2.1k 0.8×	1.8k 1.2×	1.9k 2.1×	927 1.2×	90	6.7k

Countries citing papers authored by Alexander Wree

Since Specialization

Citations

This map shows the geographic impact of Alexander Wree's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alexander Wree with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alexander Wree more than expected).

Fields of papers citing papers by Alexander Wree

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alexander Wree. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alexander Wree. The network helps show where Alexander Wree may publish in the future.

Co-authorship network of co-authors of Alexander Wree

This figure shows the co-authorship network connecting the top 25 collaborators of Alexander Wree. A scholar is included among the top collaborators of Alexander Wree based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alexander Wree. Alexander Wree is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bota, Simona, Peter Höfer, Michael Hackl, et al.. (2025). Development of Liver‐Heart Score for Early Detection of Myocardial Contractile Dysfunction in Cirrhosis by Strain Imaging. Liver International. 45(4). e70062–e70062.

Özdirik, Burcin, W Veltzke-Schlieker, Hilmar Berger, et al.. (2024). Long-term impact of scheduled regular endoscopic interventions for patients with primary sclerosing cholangitis. Hepatology Communications. 8(9). 1 indexed citations

Müller, D., et al.. (2024). Proof of Concept of Telemedicine-Assisted Abdominal Ultrasound Examinations to Improve the Quality of Patient Care in Rural Areas. Journal of Clinical Medicine. 13(6). 1721–1721.

Demir, Münevver, Alexander Wree, Tom Luedde, et al.. (2023). Atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma: Results from a German real‐world cohort. Alimentary Pharmacology & Therapeutics. 57(11). 1313–1325. 35 indexed citations

Berres, Marie‐Luise, Maria A. González-Carmona, Dominik Paul Modest, et al.. (2023). Study protocol of an open-label, single arm phase II trial investigating the efficacy and safety of Trifluridine/Tipiracil combined with irinotecan as a second line therapy in patients with cholangiocarcinoma (TRITICC). BMC Cancer. 23(1). 470–470. 2 indexed citations

Reißing, Johanna, Pavel Strnad, Alexander Wree, et al.. (2023). Th2 Cell Activation in Chronic Liver Disease Is Driven by Local IL33 and Contributes to IL13-Dependent Fibrogenesis. Cellular and Molecular Gastroenterology and Hepatology. 17(4). 517–538. 12 indexed citations

Geisler, Lukas, Raphael Mohr, Joeri Lambrecht, et al.. (2021). The Role of miRNA in the Pathophysiology of Neuroendocrine Tumors. International Journal of Molecular Sciences. 22(16). 8569–8569. 13 indexed citations

Özdirik, Burcin, Tobias Müller, Alexander Wree, Frank Tacke, & Michael Sigal. (2021). The Role of Microbiota in Primary Sclerosing Cholangitis and Related Biliary Malignancies. International Journal of Molecular Sciences. 22(13). 6975–6975. 34 indexed citations

Demir, Münevver, et al.. (2021). Shear wave elastography and shear wave dispersion imaging in primary biliary cholangitis—a pilot study. Quantitative Imaging in Medicine and Surgery. 12(2). 1235–1242. 16 indexed citations

10.

Özdirik, Burcin, Raphael Mohr, Lukas Geisler, et al.. (2020). Analysis of miR-29 Serum Levels in Patients with Neuroendocrine Tumors—Results from an Exploratory Study. Journal of Clinical Medicine. 9(9). 2881–2881. 8 indexed citations

11.

Mohr, Raphael, Burcin Özdirik, Alexander Wree, et al.. (2020). In Vivo Models for Cholangiocarcinoma—What Can We Learn for Human Disease?. International Journal of Molecular Sciences. 21(14). 4993–4993. 11 indexed citations

12.

Mohr, Raphael, Lukas Geisler, Alexander Wree, et al.. (2020). Serum levels of miR-223 but not miR-21 are decreased in patients with neuroendocrine tumors. PLoS ONE. 15(12). e0244504–e0244504. 4 indexed citations

13.

Özdirik, Burcin, Lukas Geisler, Raphael Mohr, et al.. (2020). Soluble Urokinase Plasminogen Activator Receptor (suPAR) Concentrations Are Elevated in Patients with Neuroendocrine Malignancies. Journal of Clinical Medicine. 9(6). 1647–1647. 10 indexed citations

14.

Mridha, Auvro R., Alexander Wree, Avril A. B. Robertson, et al.. (2017). NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice. Journal of Hepatology. 66(5). 1037–1046. 863 indexed citations breakdown →

15.

Johnson, Casey D., Alexander Wree, Davide Povero, et al.. (2016). Hepatic Stellate Cell Specific NLRP3 Inflammasome Activation Results in Spontaneous Fibrosis. RWTH Publications (RWTH Aachen). 1 indexed citations

16.

Adams, Leon A., Alexander Wree, Phillip E. Melton, et al.. (2015). Serum marker of inflammasome activity correlates with liver injury in nonalcoholic fatty liver disease and is influenced by genetic polymorphisms. Hepatology. 62. 2 indexed citations

17.

Povero, Davide, Akiko Eguchi, Clarence A. Johnson, et al.. (2013). 75 HEPATOCYTE-DERIVED MICROPARTICLES WITH A SPECIFIC ANTIGENIC COMPOSITION ARE RELEASED IN BLOOD DURING NASH DEVELOPMENT: IMPLICATIONS FOR BIOMARKERS DEVELOPMENT. Journal of Hepatology. 58. S34–S34. 2 indexed citations

18.

Wree, Alexander, Christoph Jochum, Lars P. Bechmann, et al.. (2013). High age and low sodium urine concentration are associated with poor survival in patients with hepatorenal syndrome. Annals of Hepatology. 12(1). 92–99. 9 indexed citations

19.

Mayer, Arnulf, Michael Hoeckel, Angelika von Wallbrunn, et al.. (2009). HIF-Mediated Hypoxic Response is Missing in Severely Hypoxic Uterine Leiomyomas. Advances in experimental medicine and biology. 662. 399–405. 21 indexed citations

20.

Mayer, Arnulf, Michael Höckel, Alexander Wree, et al.. (2008). Lack of Hypoxic Response in Uterine Leiomyomas despite Severe Tissue Hypoxia. Cancer Research. 68(12). 4719–4726. 76 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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