Alessandra Boletta

5.9k total citations · 2 hit papers
73 papers, 4.5k citations indexed

About

Alessandra Boletta is a scholar working on Genetics, Molecular Biology and Pathology and Forensic Medicine. According to data from OpenAlex, Alessandra Boletta has authored 73 papers receiving a total of 4.5k indexed citations (citations by other indexed papers that have themselves been cited), including 63 papers in Genetics, 52 papers in Molecular Biology and 24 papers in Pathology and Forensic Medicine. Recurrent topics in Alessandra Boletta's work include Genetic and Kidney Cyst Diseases (61 papers), Renal and related cancers (28 papers) and Biomedical Research and Pathophysiology (23 papers). Alessandra Boletta is often cited by papers focused on Genetic and Kidney Cyst Diseases (61 papers), Renal and related cancers (28 papers) and Biomedical Research and Pathophysiology (23 papers). Alessandra Boletta collaborates with scholars based in Italy, United States and United Kingdom. Alessandra Boletta's co-authors include Feng Qian, Gregory G. Germino, Anil K. Bhunia, Klaus Piontek, William B. Guggino, Marco Chiaravalli, Isaline Rowe, Kazushige Hanaoka, Leonidas Tsiokas and Vikas P. Sukhatme and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Alessandra Boletta

70 papers receiving 4.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

2000 661 citations Kazushige Hanaoka, Feng Qian et al. profile →
Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy

2013 384 citations Isaline Rowe, Marco Chiaravalli et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Alessandra Boletta Italy	33	3.4k	3.2k	1.2k	531	319	73	4.5k
Guanqing Wu United States	28	3.1k 0.9×	3.0k 1.0×	1.0k 0.8×	478 0.9×	241 0.8×	45	4.3k
Terry Watnick United States	41	4.2k 1.2×	3.5k 1.1×	1.1k 0.9×	374 0.7×	459 1.4×	78	5.3k
Oxana Ibraghimov‐Beskrovnaya United States	29	2.0k 0.6×	3.7k 1.1×	624 0.5×	795 1.5×	203 0.6×	43	4.6k
Yoshiko Maeda Japan	18	1.3k 0.4×	1.4k 0.4×	586 0.5×	216 0.4×	69 0.2×	41	2.5k
Matias Simons Germany	25	1.1k 0.3×	2.4k 0.8×	235 0.2×	705 1.3×	1.2k 3.7×	39	3.5k
Marjo Kestilä Finland	23	1.2k 0.4×	2.7k 0.8×	510 0.4×	277 0.5×	2.6k 8.2×	48	4.8k
Uwe Kornak Germany	36	1.2k 0.3×	3.3k 1.0×	190 0.2×	700 1.3×	147 0.5×	136	5.1k
Miyuki Suzawa Japan	27	842 0.2×	1.7k 0.5×	376 0.3×	259 0.5×	164 0.5×	38	3.1k
Michael R. Bösl Germany	28	498 0.1×	3.4k 1.1×	240 0.2×	722 1.4×	133 0.4×	40	5.0k
Philippe M. Campeau Canada	33	1.0k 0.3×	1.8k 0.6×	172 0.1×	298 0.6×	51 0.2×	123	3.3k

Countries citing papers authored by Alessandra Boletta

Since Specialization

Citations

This map shows the geographic impact of Alessandra Boletta's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alessandra Boletta with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alessandra Boletta more than expected).

Fields of papers citing papers by Alessandra Boletta

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alessandra Boletta. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alessandra Boletta. The network helps show where Alessandra Boletta may publish in the future.

Co-authorship network of co-authors of Alessandra Boletta

This figure shows the co-authorship network connecting the top 25 collaborators of Alessandra Boletta. A scholar is included among the top collaborators of Alessandra Boletta based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alessandra Boletta. Alessandra Boletta is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Boletta, Alessandra & Michael J. Caplan. (2025). Physiologic mechanisms underlying polycystic kidney disease. Physiological Reviews. 105(3). 1553–1607. 7 indexed citations

Boletta, Alessandra, et al.. (2025). Metabolic reprogramming in polycystic kidney disease and other renal ciliopathies. EMBO Molecular Medicine. 17(6). 1191–1202.

Boletta, Alessandra, et al.. (2024). Exquisite sensitivity of Polycystin-1 to H2O2 concentration in the endoplasmic reticulum. Redox Biology. 80. 103486–103486. 1 indexed citations

Podrini, Christine, Davide Stefanoni, Gianfranco Distefano, et al.. (2024). Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression. EMBO Molecular Medicine. 16(6). 1379–1403. 5 indexed citations

Boletta, Alessandra, et al.. (2024). Mitochondria remodeling during endometrial stromal cell decidualization. Life Science Alliance. 7(12). e202402627–e202402627. 4 indexed citations

Nigro, Elisa Agnese, Laura Cassina, Christine Podrini, et al.. (2023). Primary cilia sense glutamine availability and respond via asparagine synthetase. Nature Metabolism. 5(3). 385–397. 20 indexed citations

Donati, Giulio, Paola Nicoli, Alessandro Verrecchia, et al.. (2023). Oxidative stress enhances the therapeutic action of a respiratory inhibitor in MYC ‐driven lymphoma. EMBO Molecular Medicine. 15(6). e16910–e16910. 10 indexed citations

Boletta, Alessandra, et al.. (2019). In SILICO Simulations Predict a Causative Link Between Increased Glycolysis and Metabolic Reprogramming in Autosomal Dominant Polycystic Kidney Disease. 1–9. 1 indexed citations

Podrini, Christine, Laura Cassina, & Alessandra Boletta. (2019). Metabolic reprogramming and the role of mitochondria in polycystic kidney disease. Cellular Signalling. 67. 109495–109495. 80 indexed citations

10.

Padovano, Valeria, Christine Podrini, Alessandra Boletta, & Michael J. Caplan. (2018). Metabolism and mitochondria in polycystic kidney disease research and therapy. Nature Reviews Nephrology. 14(11). 678–687. 131 indexed citations

11.

Rowe, Isaline & Alessandra Boletta. (2014). Defective metabolism in polycystic kidney disease: potential for therapy and open questions. Nephrology Dialysis Transplantation. 29(8). 1480–1486. 30 indexed citations

12.

Franco, Irene, Federico Gulluni, Carlo Cosimo Campa, et al.. (2014). PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function. Developmental Cell. 28(6). 647–658. 158 indexed citations

13.

Chitalia, Vipul C., Mikhail V. Panchenko, Lirong Zeng, et al.. (2012). Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1. Human Molecular Genetics. 21(26). 5456–5471. 15 indexed citations

14.

Torres, Vicente E., Alessandra Boletta, Arlene B. Chapman, et al.. (2010). Prospects for mTOR Inhibitor Use in Patients with Polycystic Kidney Disease and Hamartomatous Diseases. Clinical Journal of the American Society of Nephrology. 5(7). 1312–1329. 74 indexed citations

15.

Boca, Manila, Lisa D’Amato, Gianfranco Distefano, et al.. (2007). Polycystin-1 Induces Cell Migration by Regulating Phosphatidylinositol 3-kinase-dependent Cytoskeletal Rearrangements and GSK3β-dependent Cell–Cell Mechanical Adhesion. Molecular Biology of the Cell. 18(10). 4050–4061. 91 indexed citations

16.

Bhunia, Anil K., Klaus Piontek, Alessandra Boletta, et al.. (2002). PKD1 Induces p21waf1 and Regulation of the Cell Cycle via Direct Activation of the JAK-STAT Signaling Pathway in a Process Requiring PKD2. Cell. 109(2). 157–168. 351 indexed citations

17.

Qian, Feng, Alessandra Boletta, Anil K. Bhunia, et al.. (2002). Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations. Proceedings of the National Academy of Sciences. 99(26). 16981–16986. 240 indexed citations

18.

Boletta, Alessandra, Feng Qian, Luiz F. Onuchic, et al.. (2000). Polycystin-1, the Gene Product of PKD1, Induces Resistance to Apoptosis and Spontaneous Tubulogenesis in MDCK Cells. Molecular Cell. 6(5). 1267–1273. 188 indexed citations

19.

Bragonzi, Alessandra, Alessandra Boletta, Alessandra Biffi, et al.. (1999). Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs. Gene Therapy. 6(12). 1995–2004. 125 indexed citations

20.

Boletta, Alessandra, Ariela Benigni, Jens Lutz, et al.. (1997). Nonviral Gene Delivery to the Rat Kidney with Polyethylenimine. Human Gene Therapy. 8(10). 1243–1251. 156 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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