Akihiro Tasaka

938 citations

29 papers · 744 indexed · h-index 16

Co-authors: Tomohiro Kaku Takahito Hara Masuo Yamaoka Masami Kusaka Akio Ojida Thomas D. Bannister William Roush Karl A. Scheidt
Topics: Synthesis and biological activity (8 papers)Hormonal and reproductive studies (6 papers)Synthesis and Biological Evaluation (6 papers)
Cited by: Organic Chemistry Pharmacology Endocrinology, Diabetes and Metabolism
Journals: Journal of the American Chemical Society Angewandte Chemie International Edition Journal of Medicinal Chemistry
Partner nations: Japan United States

In The Last Decade

Akihiro Tasaka

29 papers receiving 718 citations

Peers

Countries citing papers authored by Akihiro Tasaka

Since Specialization

Citations

This map shows the geographic impact of Akihiro Tasaka's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Akihiro Tasaka with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Akihiro Tasaka more than expected).

Fields of papers citing papers by Akihiro Tasaka

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Akihiro Tasaka. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Akihiro Tasaka. The network helps show where Akihiro Tasaka may publish in the future.

Co-authorship network of co-authors of Akihiro Tasaka

This figure shows the co-authorship network connecting the top 25 collaborators of Akihiro Tasaka. A scholar is included among the top collaborators of Akihiro Tasaka based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Akihiro Tasaka. Akihiro Tasaka is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part I 2015 ·Bioorganic & Medicinal Chemistry ·Katsuji Aikawa,(unknown),Takenori Hitaka,Yumi Imai,Takahito Hara,Jun‐ichi Miyazaki,Masuo Yamaoka,Masami Kusaka,Naoyuki Kanzaki,Akihiro Tasaka,Mitsuru Shiraishi,Satoshi Yamamoto	19
2	Effect of an investigational CYP17A1 inhibitor, orteronel (TAK-700), on estrogen- and corticoid-synthesis pathways in hypophysectomized female rats and on the serum estradiol levels in female cynomolgus monkeys 2013 ·The Journal of Steroid Biochemistry and Molecular Biology ·Masuo Yamaoka,Takahito Hara,Hideo Araki,Tomohiro Kaku,Takenori Hitaka,Akihiro Tasaka,Masami Kusaka	6
3	Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: Effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys 2012 ·The Journal of Steroid Biochemistry and Molecular Biology ·Masuo Yamaoka,Takahito Hara,Takenori Hitaka,Tomohiro Kaku,Toshiyuki Takeuchi,Junzo Takahashi,Satoru Asahi,Hiroshi Miki,Akihiro Tasaka,Masami Kusaka	98
4	Effect of a novel 17,20-lyase inhibitor, orteronel (TAK-700), on androgen synthesis in male rats 2012 ·The Journal of Steroid Biochemistry and Molecular Biology ·Takahito Hara,(unknown),Tomohiro Kaku,Toshiyuki Takeuchi,Masami Kusaka,Akihiro Tasaka,Masuo Yamaoka	28
5	Design, synthesis, and biological evaluation of 4-phenylpyrrole derivatives as novel androgen receptor antagonists 2011 ·Bioorganic & Medicinal Chemistry ·Satoshi Yamamoto,Nobuyuki Matsunaga,Takenori Hitaka,Masami Yamada,Takahito Hara,Jun‐ichi Miyazaki,Takashi Santou,Masami Kusaka,Masuo Yamaoka,Naoyuki Kanzaki,Shuichi Furuya,Akihiro Tasaka,(unknown),Mitsuhiro Ito	18
6	17,20-Lyase inhibitors. Part 4: Design, synthesis and structure–activity relationships of naphthylmethylimidazole derivatives as novel 17,20-lyase inhibitors 2011 ·Bioorganic & Medicinal Chemistry ·Tomohiro Kaku,Nobuyuki Matsunaga,Akio Ojida,Toshimasa Tanaka,Takahito Hara,Masuo Yamaoka,Masami Kusaka,Akihiro Tasaka	8
7	Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer 2011 ·Bioorganic & Medicinal Chemistry ·Tomohiro Kaku,Takenori Hitaka,Akio Ojida,Nobuyuki Matsunaga,(unknown),Toshimasa Tanaka,Takahito Hara,Masuo Yamaoka,Masami Kusaka,Teruaki Okuda,Satoru Asahi,Shuichi Furuya,Akihiro Tasaka	103
8	17,20-Lyase inhibitors. Part 3: Design, synthesis, and structure–activity relationships of biphenylylmethylimidazole derivatives as novel 17,20-lyase inhibitors 2011 ·Bioorganic & Medicinal Chemistry ·Tomohiro Kaku,(unknown),Nobuyuki Matsunaga,Toshimasa Tanaka,Takahito Hara,Masuo Yamaoka,Masami Kusaka,Akihiro Tasaka	4
9	C17,20-lyase inhibitors. Part 2: Design, synthesis and structure–activity relationships of (2-naphthylmethyl)-1H-imidazoles as novel C17,20-lyase inhibitors 2004 ·Bioorganic & Medicinal Chemistry ·Nobuyuki Matsunaga,Tomohiro Kaku,Akio Ojida,Toshimasa Tanaka,Takahito Hara,Masuo Yamaoka,Masami Kusaka,Akihiro Tasaka	47
10	C17,20-Lyase inhibitors I. Structure-based de novo design and SAR study of C17,20-lyase inhibitors 2004 ·Bioorganic & Medicinal Chemistry ·Nobuyuki Matsunaga,Tomohiro Kaku,Fumio Itoh,Toshimasa Tanaka,Takahito Hara,Hiroshi Miki,M. Iwasaki,(unknown),Masuo Yamaoka,Masami Kusaka,Akihiro Tasaka	34
11	Synthetic studies on (1S)-1-(6,7-dimethoxy-2-naphthyl)-1-(1H-imidazol-4-yl)-2-methylpropan-1-ol as a selective C17,20-lyase inhibitor 2004 ·Tetrahedron Asymmetry ·Nobuyuki Matsunaga,Tomohiro Kaku,Akio Ojida,Akihiro Tasaka	11
12	Optically Active Antifungal Azoles. VIII. Synthesis and Antifungal Activity of 1-((1R,2R)-2-(2,4-Difluoro- and 2-Fluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl)-3-(4-substituted phenyl)-2(1H,3H)-imidazolones and 2-Imidazolidinones. 1999 ·Chemical and Pharmaceutical Bulletin ·Tomoyuki Kitazaki,Akihiro Tasaka,Norikazu Tamura,Yoshihiro Matsushita,(unknown),(unknown),Kenji Okonogi,Katsumi Itoh	1
13	Total Synthesis of (−)-Bafilomycin A1: Application of Diastereoselective Crotylboration and Methyl Ketone Aldol Reactions 1999 ·Angewandte Chemie International Edition ·Karl A. Scheidt,Akihiro Tasaka,Thomas D. Bannister,Michael Wendt,William Roush	42
14	Optically Active Antifungal Azoles. IX. An Alternative Synthetic Route for 2-((1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl)-4-(4-(2,2,3,3-tetrafluoropropoxy)phenyl)-3(2H,4H)-1,2,4-triazolone and Its Analogs. 1999 ·Chemical and Pharmaceutical Bulletin ·Tomoyuki Kitazaki,Akihiro Tasaka,(unknown),Yoshihiro Matsushita,(unknown)	9
15	Optically Active Antifungal Azoles. VII. Synthesis and Antifungal Activity of Stereoisomers of 2-((1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl)-4-(4-(2,2,3,3-tetrafluoropropoxy)phenyl)-3(2H,4H)-1,2,4-triazolone (TAK-187). 1997 ·Chemical and Pharmaceutical Bulletin ·Akihiro Tasaka,Tomoyuki Kitazaki,Noboru Tsuchimori,Yoshihiro Matsushita,Rina Hayashi,Kenji Okonogi,Katsumi Itoh	16
16	Optically Active Antifungal Azoles. VI. Synthesis and Antifungal Activity of N-((1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl)-N'-(4-substituted phenyl)-3(2H,4H)-1,2,4-triazolones and 5(1H,4H)-tetrazolones. 1996 ·Chemical and Pharmaceutical Bulletin ·Tomoyuki Kitazaki,Norikazu Tamura,Akihiro Tasaka,Yoshihiro Matsushita,(unknown),Kenji Okonogi,Katsumi Itoh	25
17	Optically Active Antifungal Azoles. IV. Synthesis and Antifungal Activity of (2R,3R)-3-Azolyl-2-(substituted phenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanols. 1995 ·Chemical and Pharmaceutical Bulletin ·Akihiro Tasaka,Norikazu Tamura,Yoshihiro Matsushita,Tomoyuki Kitazaki,(unknown),Kenji Okonogi,Katsumi Itoh	16
18	Optically Active Antifungal Azoles. III. Synthesis and Antifungal Activity of Sulfide and Sulfonamide Derivatives of (2R,3R)-2-(2,4-Difluorophenyl)-3-mercapto-1- (lH-1,2,4-triazol-1-yl)-2-butanol. 1994 ·Chemical and Pharmaceutical Bulletin ·Akihiro Tasaka,Katsunori Teranishi,Yoshihiro Matsushita,Norikazu Tamura,(unknown),Kenji Okonogi,Katsumi Itoh	15
19	Optically Active Antifungal Azoles. II. Synthesis and Antifungal Activity of Polysulfide Derivatives of (2R,3R)-2-(2,4-Difluorophenyl)-3-mercapto-1-(1H-1,2,4-triazol-1-yl)-2-butanol. 1993 ·Chemical and Pharmaceutical Bulletin ·Akihiro Tasaka,Norikazu Tamura,Yoshihiro Matsushita,(unknown),Kenji Okonogi,(unknown)	22
20	Optically Active Antifungal Azoles. I. Synthesis and Antifungal Activity of (2R,3R)-2-(2,4-Difluorophenyl)-3-mercapto-1-(1H-1,2,4-triazol-1-yl)-2-butanol and Its Stereoisomers. 1993 ·Chemical and Pharmaceutical Bulletin ·Akihiro Tasaka,Norikazu Tamura,Yoshihiro Matsushita,Katsunori Teranishi,(unknown),Kenji Okonogi,Katsumi Itoh	36

About Akihiro Tasaka

Akihiro Tasaka is a scholar working on Organic Chemistry, Endocrinology, Diabetes and Metabolism and Pharmaceutical Science, having authored 29 papers that have together received 744 indexed citations. Recurring topics across this work include Synthesis and biological activity (8 papers), Hormonal and reproductive studies (6 papers) and Synthesis and Biological Evaluation (6 papers). The work is most often cited by research in Organic Chemistry (365 citations), Pharmacology (87 citations) and Endocrinology, Diabetes and Metabolism (148 citations). Akihiro Tasaka has collaborated with scholars based in Japan and United States. Frequent co-authors include Tomohiro Kaku, Takahito Hara, Masuo Yamaoka, Masami Kusaka, Akio Ojida, Thomas D. Bannister, William Roush, Karl A. Scheidt, Michael Wendt and Nobuyuki Matsunaga. Their work appears in journals such as Journal of the American Chemical Society, Angewandte Chemie International Edition and Journal of Medicinal Chemistry.

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