A. Ruf

4.0k total citations · 2 hit papers
36 papers, 3.1k citations indexed

About

A. Ruf is a scholar working on Molecular Biology, Physiology and Biochemistry. According to data from OpenAlex, A. Ruf has authored 36 papers receiving a total of 3.1k indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Molecular Biology, 5 papers in Physiology and 5 papers in Biochemistry. Recurrent topics in A. Ruf's work include Receptor Mechanisms and Signaling (6 papers), Enzyme Structure and Function (5 papers) and Peroxisome Proliferator-Activated Receptors (4 papers). A. Ruf is often cited by papers focused on Receptor Mechanisms and Signaling (6 papers), Enzyme Structure and Function (5 papers) and Peroxisome Proliferator-Activated Receptors (4 papers). A. Ruf collaborates with scholars based in Switzerland, Germany and France. A. Ruf's co-authors include M. Stihle, Michael Hennig, Jörg Benz, Georg E. Schulz, Ralf Thoma, Arne C. Rufer, Gilbert de Murcia, Walter Huber, Toon Laeremans and Jan Steyaert and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

A. Ruf

36 papers receiving 3.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose

2011 594 citations Claudia Ferrara, Sandra Grau et al. Proceedings of the National Academy of Sciences profile →
A general protocol for the generation of Nanobodies for structural biology

2014 554 citations Els Pardon, Toon Laeremans et al. Nature Protocols profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
A. Ruf Switzerland	26	2.2k	841	597	532	215	36	3.1k
Kazuki Saito Japan	29	1.8k 0.8×	559 0.7×	776 1.3×	209 0.4×	206 1.0×	83	2.9k
W.S. Somers United States	28	2.4k 1.1×	435 0.5×	630 1.1×	974 1.8×	361 1.7×	37	4.3k
Torleif Härd Sweden	42	4.3k 1.9×	741 0.9×	556 0.9×	353 0.7×	272 1.3×	111	5.8k
Daniel F. Wyss United States	31	1.6k 0.7×	447 0.5×	323 0.5×	454 0.9×	382 1.8×	58	3.4k
Michael Hennig Switzerland	38	3.2k 1.4×	915 1.1×	735 1.2×	427 0.8×	620 2.9×	88	4.9k
Antonio Casamayor Spain	29	5.3k 2.4×	724 0.9×	277 0.5×	242 0.5×	121 0.6×	67	6.0k
Jörg Benz Switzerland	34	2.8k 1.3×	689 0.8×	296 0.5×	482 0.9×	635 3.0×	67	4.3k
John E. Harlan United States	22	4.5k 2.0×	244 0.3×	836 1.4×	693 1.3×	247 1.1×	40	5.8k
John Matsoukas Greece	31	1.9k 0.9×	353 0.4×	244 0.4×	857 1.6×	479 2.2×	189	3.3k
Seong Eon Ryu South Korea	31	2.0k 0.9×	242 0.3×	547 0.9×	658 1.2×	224 1.0×	97	3.0k

Countries citing papers authored by A. Ruf

Since Specialization

Citations

This map shows the geographic impact of A. Ruf's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by A. Ruf with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites A. Ruf more than expected).

Fields of papers citing papers by A. Ruf

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by A. Ruf. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by A. Ruf. The network helps show where A. Ruf may publish in the future.

Co-authorship network of co-authors of A. Ruf

This figure shows the co-authorship network connecting the top 25 collaborators of A. Ruf. A scholar is included among the top collaborators of A. Ruf based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with A. Ruf. A. Ruf is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Rufer, Arne C., Eric A. Kusznir, Dominique Burger, et al.. (2018). Domain swap in the C-terminal ubiquitin-like domain of human doublecortin. Acta Crystallographica Section D Structural Biology. 74(5). 450–462. 5 indexed citations

Shahmoradian, Sarah H., Esther H. R. Tsai, Ana Díaz, et al.. (2017). Three-Dimensional Imaging of Biological Tissue by Cryo X-Ray Ptychography. Scientific Reports. 7(1). 6291–6291. 51 indexed citations

Huber, Walter, et al.. (2015). Elucidation of direct competition and allosteric modulation of small-molecular-weight protein ligands using surface plasmon resonance methods. Journal of Molecular Recognition. 28(8). 480–491. 2 indexed citations

Pardon, Els, Toon Laeremans, Sarah Triest, et al.. (2014). A general protocol for the generation of Nanobodies for structural biology. Nature Protocols. 9(3). 674–693. 554 indexed citations breakdown →

Ruf, A., Peter Stohler, T. Tetaz, et al.. (2012). Crystal structure of acid-sensing ion channel 1 in complex with the gating modifier psalmotoxin 1. Acta Crystallographica Section A Foundations of Crystallography. 68(a1). s160–s160. 1 indexed citations

Mohr, Peter, Bernd Kuhn, Hans Peter Maerki, et al.. (2012). Comparative Molecular Profiling of the PPARα/γ Activator Aleglitazar: PPAR Selectivity, Activity and Interaction with Cofactors. ChemMedChem. 7(6). 1101–1111. 37 indexed citations

Ruf, A., M. Stihle, Jörg Benz, Manfred Schmidt, & Harald Sobek. (2012). Structure of Gentlyase, the neutral metalloprotease ofPaenibacillus polymyxa. Acta Crystallographica Section D Biological Crystallography. 69(1). 24–31. 11 indexed citations

Ferrara, Claudia, Sandra Grau, Christiane Jäger, et al.. (2011). Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose. Proceedings of the National Academy of Sciences. 108(31). 12669–12674. 594 indexed citations breakdown →

Hebeisen, Paul, Wolfgang Haap, Bernd Kuhn, et al.. (2011). Orally active aminopyridines as inhibitors of tetrameric fructose-1,6-bisphosphatase. Bioorganic & Medicinal Chemistry Letters. 21(11). 3237–3242. 14 indexed citations

10.

Hennig, Michael, A. Ruf, & Walter Huber. (2011). Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery. Topics in current chemistry. 317. 115–143. 36 indexed citations

11.

Pappenberger, Florian, Jörg Benz, Bernard Gsell, et al.. (2010). Structure of the Human Fatty Acid Synthase KS–MAT Didomain as a Framework for Inhibitor Design. Journal of Molecular Biology. 397(2). 508–519. 48 indexed citations

12.

Seitz, Tobias, Ralf Thoma, G. Schoch, et al.. (2010). Enhancing the Stability and Solubility of the Glucocorticoid Receptor Ligand-Binding Domain by High-Throughput Library Screening. Journal of Molecular Biology. 403(4). 562–577. 41 indexed citations

13.

Schoch, G., Brigitte D’Arcy, M. Stihle, et al.. (2009). Molecular Switch in the Glucocorticoid Receptor: Active and Passive Antagonist Conformations. Journal of Molecular Biology. 395(3). 568–577. 99 indexed citations

14.

Bénardeau, Agnès, Jörg Benz, Alfred Binggeli, et al.. (2009). Aleglitazar, a new, potent, and balanced dual PPARα/γ agonist for the treatment of type II diabetes. Bioorganic & Medicinal Chemistry Letters. 19(9). 2468–2473. 85 indexed citations

15.

Kitas, Eric, Peter J. Mohr, Bernd Kuhn, et al.. (2009). Sulfonylureido thiazoles as fructose-1,6-bisphosphatase inhibitors for the treatment of Type-2 diabetes. Bioorganic & Medicinal Chemistry Letters. 20(2). 594–599. 25 indexed citations

16.

Hebeisen, Paul, Bernd Kuhn, Philipp Köhler, et al.. (2008). Allosteric FBPase inhibitors gain 105 times in potency when simultaneously binding two neighboring AMP sites. Bioorganic & Medicinal Chemistry Letters. 18(16). 4708–4712. 30 indexed citations

17.

Zhou, Lin, André Alker, A. Ruf, et al.. (2008). Characterization of the two major CYP450 metabolites of ozonide (1,2,4-trioxolane) OZ277. Bioorganic & Medicinal Chemistry Letters. 18(5). 1555–1558. 30 indexed citations

18.

Kuglstatter, A., Martin Ståhl, Jens‐Uwe Peters, et al.. (2008). Tyramine fragment binding to BACE-1. Bioorganic & Medicinal Chemistry Letters. 18(4). 1304–1307. 43 indexed citations

19.

Lerner, C., B. Masjost, A. Ruf, et al.. (2002). Bisubstrate inhibitors for the enzyme catechol-O-methyltransferase (COMT): influence of inhibitor preorganisation and linker length between the two substrate moieties on binding affinity. Organic & Biomolecular Chemistry. 1(1). 42–49. 49 indexed citations

20.

Ruf, A., Véronique Rolli, Gilbert de Murcia, & Georg E. Schulz. (1998). The mechanism of the elongation and branching reaction of Poly(ADP-ribose) polymerase as derived from crystal structures and mutagenesis. Journal of Molecular Biology. 278(1). 57–65. 147 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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