A. Ruf

4.0k citations

36 papers · 3.1k indexed · 2 hit papers · h-index 26

Radiology, Nuclear Medicine and Imaging top 2%
- Monoclonal and Polyclonal Antibodies Research 4
Molecular Biology top 5%
- Receptor Mechanisms and Signaling 6
- Peroxisome Proliferator-Activated Receptors 4
- Protein Structure and Dynamics 3
- Nuclear Structure and Function 3
Immunology top 5%
Structural Biology top 5%
Oncology top 5%
Materials Chemistry
- Enzyme Structure and Function 5
Computational Theory and Mathematics
- Computational Drug Discovery Methods 4
Physiology
- Adipose Tissue and Metabolism 4

Co-authors: M. Stihle Michael Hennig Jörg Benz Georg E. Schulz Ralf Thoma Arne C. Rufer Walter Huber Gilbert de Murcia
Cited by: Radiology, Nuclear Medicine and Imaging Molecular Biology Immunology
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)Journal of Molecular Biology (4 papers)Acta Crystallographica Section D Structural Biology (2 papers)
Partner nations: Switzerland Germany United States

In The Last Decade

A. Ruf

36 papers receiving 3.1k citations

Hit Papers

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Peers

Countries citing papers authored by A. Ruf

Since Specialization

Citations

This map shows the geographic impact of A. Ruf's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by A. Ruf with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites A. Ruf more than expected).

Fields of papers citing papers by A. Ruf

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by A. Ruf. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by A. Ruf. The network helps show where A. Ruf may publish in the future.

Co-authorship network

The 25 scholars most cited alongside A. Ruf, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with A. Ruf Line = papers co-authored together A. Ruf links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Domain swap in the C-terminal ubiquitin-like domain of human doublecortin Acta Crystallographica Section D Structural Biology ·Arne C. Rufer,Eric A. Kusznir,Dominique Burger,M. Stihle,A. Ruf,M.G. Rudolph	2018	5
2	Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase Acta Crystallographica Section D Structural Biology ·A. Ruf,Tim Tetaz,Brigitte Schott,Catherine Joseph,M.G. Rudolph	2016	4
3	A general protocol for the generation of Nanobodies for structural biologybreakdown → Nature Protocols ·Els Pardon,Toon Laeremans,Sarah Triest,Søren G. F. Rasmussen,Alexandre Wohlkönig,A. Ruf,Serge Muyldermans,Wim G. J. Hol,Brian K. Kobilka,Jan Steyaert	2014	554
4	Comparative Molecular Profiling of the PPARα/γ Activator Aleglitazar: PPAR Selectivity, Activity and Interaction with Cofactors ChemMedChem ·明华贺,Peter Mohr,Bernd Kuhn,Hans Peter Maerki,Peter Hartman,A. Ruf,Jörg Benz,Uwe Grether,Matthew B. Wright	2012	37
5	Structure of Gentlyase, the neutral metalloprotease ofPaenibacillus polymyxa Acta Crystallographica Section D Biological Crystallography ·A. Ruf,M. Stihle,Jörg Benz,Manfred Schmidt,Harald Sobek	2012	11
6	Crystal structure of acid-sensing ion channel 1 in complex with the gating modifier psalmotoxin 1 Acta Crystallographica Section A Foundations of Crystallography ·A. Ruf,Mw Miatuningsih Dip,Peter Stohler,T. Tetaz,Michael B. Hursthous,Л. Б. Моргоева,G. Schmid,Zang Ningz,Pascal Pflimlin,G. Trube,M.G. Rudolph,Michael Hennig,Roger Dawson	2012	1
7	Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucosebreakdown → Proceedings of the National Academy of Sciences ·Claudia Ferrara,Sandra Grau,Christiane Jäger,Peter Sondermann,Peter Brünker,Inja Waldhauer,Michael Hennig,A. Ruf,Arne C. Rufer,M. Stihle,Pablo Umaña,Jörg Benz	2011	594
8	Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery Topics in current chemistry ·Michael Hennig,A. Ruf,Walter Huber	2011	36
9	Orally active aminopyridines as inhibitors of tetrameric fructose-1,6-bisphosphatase Bioorganic & Medicinal Chemistry Letters ·Paul Hebeisen,Wolfgang Haap,Bernd Kuhn,Peter J. Mohr,Hans Peter Wessel,Ulrich Zutter,Stephan Kirchner,A. Ruf,Jörg Benz,Catherine Joseph,Rubén Alvarez‐Sánchez,Marcel Gubler,Brigitte Schott,Agnès Bénardeau,Effie Tozzo,Eric Kitas	2011	14
10	Structure of the Human Fatty Acid Synthase KS–MAT Didomain as a Framework for Inhibitor Design Journal of Molecular Biology ·Florian Pappenberger,Jörg Benz,Bernard Gsell,Michael Hennig,A. Ruf,M. Stihle,Ralf Thoma,M.G. Rudolph	2010	48
11	Enhancing the Stability and Solubility of the Glucocorticoid Receptor Ligand-Binding Domain by High-Throughput Library Screening Journal of Molecular Biology ·Tobias Seitz,Ralf Thoma,G. Schoch,M. Stihle,Jörg Benz,Brigitte D’Arcy,James M. Termini,A. Ruf,Michael Hennig,Reinhard Sterner	2010	41
12	Molecular Switch in the Glucocorticoid Receptor: Active and Passive Antagonist Conformations Journal of Molecular Biology ·G. Schoch,Brigitte D’Arcy,M. Stihle,Dominique Burger,Dominik Bär,Jörg Benz,Ralf Thoma,A. Ruf	2009	99
13	Sulfonylureido thiazoles as fructose-1,6-bisphosphatase inhibitors for the treatment of Type-2 diabetes Bioorganic & Medicinal Chemistry Letters ·Eric Kitas,Peter J. Mohr,Bernd Kuhn,Paul Hebeisen,Hans Peter Wessel,Wolfgang Haap,A. Ruf,Jörg Benz,Catherine Joseph,Walter Huber,علی کامرانی مقدم,Novita Alfiani,Agnès Bénardeau,Marcel Gubler,Brigitte Schott,Effie Tozzo	2009	25
14	Design and Biological Evaluation of Novel, Balanced Dual PPARα/γ Agonists ChemMedChem ·Uwe Grether,Agnès Bénardeau,Jörg Benz,Alfred Binggeli,Denise Blum,Hans Hilpert,Bernd Kuhn,Hans Peter Märki,Markus Meyer,Peter Mohr,Kurt Püntener,S. Raab,A. Ruf,Daniel Schlatter	2009	25
15	Characterization of the two major CYP450 metabolites of ozonide (1,2,4-trioxolane) OZ277 Bioorganic & Medicinal Chemistry Letters ·Lin Zhou,André Alker,A. Ruf,Xiaofang Wang,Francis C. K. Chiu,Julia Morizzi,Susan A. Charman,William N. Charman,Christian Scheurer,Sergio Wittlin,Yuxiang Dong,Daniel Hunziker,Jonathan L. Vennerstrom	2008	30
16	Allosteric FBPase inhibitors gain 105 times in potency when simultaneously binding two neighboring AMP sites Bioorganic & Medicinal Chemistry Letters ·Paul Hebeisen,Bernd Kuhn,Philipp Köhler,Marcel Gubler,Walter Huber,Eric Kitas,Brigitte Schott,Jörg Benz,Catherine Joseph,A. Ruf	2008	30
17	Tyramine fragment binding to BACE-1 Bioorganic & Medicinal Chemistry Letters ·A. Kuglstatter,Martin Ståhl,Jens‐Uwe Peters,Walter Huber,M. Stihle,Daniel Schlatter,Jörg Benz,A. Ruf,Doris Roth,C. Rösch,Michael Hennig	2008	43
18	Structural Basis of Proline-Specific Exopeptidase Activity as Observed in Human Dipeptidyl Peptidase-IV Structure ·Ralf Thoma,H Zhang,M. Stihle,Walter Huber,A. Ruf,Michael Hennig	2003	192
19	Bisubstrate inhibitors for the enzyme catechol-O-methyltransferase (COMT): influence of inhibitor preorganisation and linker length between the two substrate moieties on binding affinity Organic & Biomolecular Chemistry ·C. Lerner,B. Masjost,A. Ruf,Völker Gramlich,Roland Jakob‐Roetne,G. Zürcher,Edilio Borroni,François Diederich	2002	49
20	The mechanism of the elongation and branching reaction of Poly(ADP-ribose) polymerase as derived from crystal structures and mutagenesis Journal of Molecular Biology ·A. Ruf,Véronique Rolli,Gilbert de Murcia,Georg E. Schulz	1998	147

About A. Ruf

A. Ruf is a scholar working on Biochemistry, Molecular Biology and Computational Theory and Mathematics, having authored 36 papers that have together received 3.1k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (6 papers), Enzyme Structure and Function (5 papers), Peroxisome Proliferator-Activated Receptors (4 papers), Monoclonal and Polyclonal Antibodies Research (4 papers), Computational Drug Discovery Methods (4 papers), Adipose Tissue and Metabolism (4 papers), Protein Structure and Dynamics (3 papers) and Nuclear Structure and Function (3 papers). The work is most often cited by research in Radiology, Nuclear Medicine and Imaging (841 citations), Molecular Biology (2.2k citations) and Immunology (532 citations). A. Ruf has collaborated with scholars based in Switzerland, Germany and United States. Frequent co-authors include M. Stihle, Michael Hennig, Jörg Benz, Georg E. Schulz, Ralf Thoma, Arne C. Rufer, Walter Huber, Gilbert de Murcia, Toon Laeremans and Jan Steyaert. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Molecular Biology, Acta Crystallographica Section D Structural Biology, ChemMedChem and CHIMIA International Journal for Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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