C. Lerner

1.3k total citations
22 papers, 1.0k citations indexed

About

C. Lerner is a scholar working on Molecular Biology, Computational Theory and Mathematics and Pharmacology. According to data from OpenAlex, C. Lerner has authored 22 papers receiving a total of 1.0k indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Molecular Biology, 6 papers in Computational Theory and Mathematics and 5 papers in Pharmacology. Recurrent topics in C. Lerner's work include Chemical Synthesis and Analysis (6 papers), Computational Drug Discovery Methods (6 papers) and Protein Structure and Dynamics (5 papers). C. Lerner is often cited by papers focused on Chemical Synthesis and Analysis (6 papers), Computational Drug Discovery Methods (6 papers) and Protein Structure and Dynamics (5 papers). C. Lerner collaborates with scholars based in Switzerland, United States and France. C. Lerner's co-authors include Mark G. Charest, Dionicio Siegel, Jason D. Brubaker, Andrew G. Myers, François Diederich, Roland Jakob‐Roetne, Edilio Borroni, G. Zürcher, Völker Gramlich and A. Ruf and has published in prestigious journals such as Science, Journal of the American Chemical Society and Angewandte Chemie International Edition.

In The Last Decade

C. Lerner

21 papers receiving 978 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
C. Lerner Switzerland	18	515	431	209	203	76	22	1.0k
Thomas Lampe Germany	15	477 0.9×	422 1.0×	182 0.9×	74 0.4×	34 0.4×	22	1.2k
Vithal M. Kulkarni India	21	646 1.3×	700 1.6×	170 0.8×	384 1.9×	45 0.6×	77	1.4k
Mark McGann United States	7	893 1.7×	303 0.7×	144 0.7×	600 3.0×	157 2.1×	11	1.4k
Siegfried S. F. Leung United States	14	921 1.8×	513 1.2×	119 0.6×	188 0.9×	66 0.9×	14	1.4k
Thompson N. Doman United States	12	831 1.6×	345 0.8×	117 0.6×	501 2.5×	153 2.0×	24	1.5k
Sundarapandian Thangapandian South Korea	20	771 1.5×	214 0.5×	152 0.7×	403 2.0×	59 0.8×	44	1.2k
Patrizio Mattei Switzerland	16	462 0.9×	201 0.5×	75 0.4×	175 0.9×	120 1.6×	24	980
J. Schiebel Germany	14	514 1.0×	185 0.4×	71 0.3×	175 0.9×	191 2.5×	22	782
Simon Cross Italy	15	433 0.8×	123 0.3×	127 0.6×	332 1.6×	79 1.0×	27	738
Vladimir I. Polshakov Russia	21	708 1.4×	157 0.4×	107 0.5×	121 0.6×	198 2.6×	95	1.2k

Countries citing papers authored by C. Lerner

Since Specialization

Citations

This map shows the geographic impact of C. Lerner's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by C. Lerner with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites C. Lerner more than expected).

Fields of papers citing papers by C. Lerner

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by C. Lerner. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by C. Lerner. The network helps show where C. Lerner may publish in the future.

Co-authorship network of co-authors of C. Lerner

This figure shows the co-authorship network connecting the top 25 collaborators of C. Lerner. A scholar is included among the top collaborators of C. Lerner based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with C. Lerner. C. Lerner is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

1.

Kuhaudomlarp, Sakonwan, Annabelle Varrot, Anne Imberty, et al.. (2025). The Parkinson's Disease Drug Tolcapone and Analogues are Potent Glycomimetic Lectin Inhibitors of Pseudomonas aeruginosa LecA. Angewandte Chemie International Edition. 64(50). e202508864–e202508864.

2.

Bendels, Stefanie, Caterina Bissantz, Grégori Gerebtzoff, et al.. (2019). Safety screening in early drug discovery: An optimized assay panel. Journal of Pharmacological and Toxicological Methods. 99. 106609–106609. 41 indexed citations

3.

Zoffmann, Sannah, Maarten Vercruysse, Fethallah Benmansour, et al.. (2019). Machine learning-powered antibiotics phenotypic drug discovery. Scientific Reports. 9(1). 5013–5013. 67 indexed citations

4.

Jones, Jeremy C., Bindumadhav M. Marathe, C. Lerner, et al.. (2016). A Novel Endonuclease Inhibitor Exhibits Broad-Spectrum Anti-Influenza Virus Activity In Vitro. Antimicrobial Agents and Chemotherapy. 60(9). 5504–5514. 49 indexed citations

5.

Kuhn, Bernd, Wolfgang Guba, Jérôme Hert, et al.. (2016). A Real-World Perspective on Molecular Design. Journal of Medicinal Chemistry. 59(9). 4087–4102. 80 indexed citations

6.

Ellermann, Manuel, C. Lerner, Caterina Bissantz, et al.. (2012). Catechol-O-methyltransferase in complex with substituted 3′-deoxyribose bisubstrate inhibitors. Acta Crystallographica Section D Biological Crystallography. 68(3). 253–260. 26 indexed citations

7.

Ellermann, Manuel, Ralph Paulini, Roland Jakob‐Roetne, et al.. (2011). Molecular Recognition at the Active Site of Catechol‐O‐methyltransferase (COMT): Adenine Replacements in Bisubstrate Inhibitors. Chemistry - A European Journal. 17(23). 6369–6381. 31 indexed citations

8.

Ellermann, Manuel, Roland Jakob‐Roetne, C. Lerner, et al.. (2009). Molecular Recognition at the Active Site of Catechol‐O‐Methyltransferase: Energetically Favorable Replacement of a Water Molecule Imported by a Bisubstrate Inhibitor. Angewandte Chemie International Edition. 48(48). 9092–9096. 39 indexed citations

9.

Ellermann, Manuel, Roland Jakob‐Roetne, C. Lerner, et al.. (2009). Molekulare Erkennung in der aktiven Tasche der Catechol‐O‐ Methyltransferase: energetisch günstige Verdrängung eines von einem Bisubstratinhibitor importierten Wassermoleküls. Angewandte Chemie. 121(48). 9256–9260. 17 indexed citations

10.

Sun, Cuixiang, Qiu Wang, Jason D. Brubaker, et al.. (2008). A Robust Platform for the Synthesis of New Tetracycline Antibiotics. Journal of the American Chemical Society. 130(52). 17913–17927. 103 indexed citations

11.

Paulini, Ralph, Christian Trindler, C. Lerner, et al.. (2006). Bisubstrate Inhibitors of Catechol O‐Methyltransferase (COMT): the Crucial Role of the Ribose Structural Unit for Inhibitor Binding Affinity. ChemMedChem. 1(3). 340–357. 22 indexed citations

12.

Charest, Mark G., C. Lerner, Jason D. Brubaker, Dionicio Siegel, & Andrew G. Myers. (2005). A Convergent Enantioselective Route to Structurally Diverse 6-Deoxytetracycline Antibiotics. Science. 308(5720). 395–398. 248 indexed citations

13.

Paulini, Ralph, C. Lerner, Roland Jakob‐Roetne, et al.. (2004). Bisubstrate Inhibitors of the Enzyme Catechol O‐Methyltransferase (COMT): Efficient Inhibition Despite the Lack of a Nitro Group. ChemBioChem. 5(9). 1270–1274. 31 indexed citations

14.

Lerner, C., Romain Siegrist, Eliane Schweizer, et al.. (2003). Bisubstrate Inhibitors for the Enzyme Catechol O‐Methyltransferase (COMT): Dramatic Effects of Ribose Modifications on Binding Affinity and Binding Mode. Helvetica Chimica Acta. 86(4). 1045–1062. 17 indexed citations

15.

Lerner, C., B. Masjost, A. Ruf, et al.. (2002). Bisubstrate inhibitors for the enzyme catechol-O-methyltransferase (COMT): influence of inhibitor preorganisation and linker length between the two substrate moieties on binding affinity. Organic & Biomolecular Chemistry. 1(1). 42–49. 49 indexed citations

16.

Lerner, C., A. Ruf, Völker Gramlich, et al.. (2001). X-ray Crystal Structure of a Bisubstrate Inhibitor Bound to the Enzyme Catechol-O-methyltransferase: A Dramatic Effect of Inhibitor Preorganization on Binding Affinity We thank F. Hoffmann–La Roche for generous support of this work. We are grateful to P. Malherbe for the cloning of COMT, P. Caspers for the expression of COMT, A. Cesura for enzyme purification, B. Wipf for fermentation, and H. W. Lahm for sequencing.. Angewandte Chemie International Edition. 40(21). 4040–4040. 57 indexed citations

17.

Lerner, C., A. Ruf, Völker Gramlich, et al.. (2001). X-ray Crystal Structure of a Bisubstrate Inhibitor Bound to the Enzyme Catechol-O-methyltransferase: A Dramatic Effect of Inhibitor Preorganization on Binding Affinity. Angewandte Chemie. 113(21). 4164–4166. 49 indexed citations

18.

Obst, U., C. Lerner, Paul Seiler, et al.. (2000). Synthesis of Novel Nonpeptidic Thrombin Inhibitors. Helvetica Chimica Acta. 83(5). 855–909. 64 indexed citations

19.

Obst, U., C. Lerner, Paul Seiler, et al.. (2000). ChemInform Abstract: Synthesis of Novel Nonpeptidic Thrombin Inhibitors.. ChemInform. 31(30). 1 indexed citations

20.

Lerner, C., et al.. (2000). Molecular Recognition with Biological Receptors: Structure-Based Design of Thrombin Inhibitors. CHIMIA International Journal for Chemistry. 54(11). 633–633. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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