A. Robert MacLeod

3.4k citations

26 papers · 2.5k indexed · 1 hit paper · h-index 22

Co-authors: Moshe Szyf Normand Beaulieu Marie‐France Robert Steves Morin Ian C. Chute France Gauthier Annie Barsalou Jeffrey M. Besterman
Topics: Epigenetics and DNA Methylation (18 papers)Cancer-related gene regulation (10 papers)RNA modifications and cancer (8 papers)
Cited by: Molecular Biology Cancer Research Oncology
Journals: Proceedings of the National Academy of Sciences Journal of Biological Chemistry Nature Genetics
Partner nations: Canada United States France

In The Last Decade

A. Robert MacLeod

26 papers receiving 2.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

2002 507 citations Marie‐France Robert, Steves Morin et al. Nature Genetics profile →

Peers

Countries citing papers authored by A. Robert MacLeod

Since Specialization

Citations

This map shows the geographic impact of A. Robert MacLeod's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by A. Robert MacLeod with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites A. Robert MacLeod more than expected).

Fields of papers citing papers by A. Robert MacLeod

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by A. Robert MacLeod. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by A. Robert MacLeod. The network helps show where A. Robert MacLeod may publish in the future.

Co-authorship network of co-authors of A. Robert MacLeod

This figure shows the co-authorship network connecting the top 25 collaborators of A. Robert MacLeod. A scholar is included among the top collaborators of A. Robert MacLeod based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with A. Robert MacLeod. A. Robert MacLeod is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Telomere length is key to hepatocellular carcinoma diversity and telomerase addiction is an actionable therapeutic target 2020 ·Journal of Hepatology ·Massih Ningarhari,Stefano Caruso,Théo Z. Hirsch,Quentin Bayard,Andrea Franconi,Anne‐Laure Védié,(unknown),Jean‐Frédéric Blanc,Giuliana Amaddeo,Nathalie Ganne‐Carrié,Marianne Ziol,Valérie Paradis,Catherine Guettier,Julien Caldéraro,Guillaume Morcrette,Youngsoo Kim,A. Robert MacLeod,Jean‐Charles Nault,Sandra Rebouissou,Jessica Zucman‐Rossi	73
2	Identification of potent and selective VEGFR receptor tyrosine kinase inhibitors having new amide isostere headgroups 2010 ·Bioorganic & Medicinal Chemistry Letters ·Frédéric Gaudette,Stéphane Raeppel,Hannah Nguyen,Normand Beaulieu,Carole Beaulieu,Isabelle Dupont,A. Robert MacLeod,Jeffrey M. Besterman,Arkadii Vaisburg	16
3	Identification of a novel series of potent RON receptor tyrosine kinase inhibitors 2010 ·Bioorganic & Medicinal Chemistry Letters ·Stéphane Raeppel,Frédéric Gaudette,Michael R. Mannion,Stephen Claridge,(unknown),(unknown),Robert Déziel,Normand Beaulieu,Carole Beaulieu,Isabelle Dupont,Hannah Nguyen,Jinru Wang,A. Robert MacLeod,Christiane R. Maroun,Jeffrey M. Besterman,Arkadii Vaisburg	11
4	N3-Arylmalonamides: A new series of thieno[3,2-b]pyridine based inhibitors of c-Met and VEGFR2 tyrosine kinases 2009 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Stephen Claridge,(unknown),Franck Raeppel,(unknown),Stéphane Raeppel,Michael R. Mannion,Frédéric Gaudette,Nancy Zhou,(unknown),Naomy Bernstein,Robert Déziel,Hannah Nguyen,Normand Beaulieu,Carole Beaulieu,Isabelle Dupont,Jinru Wang,A. Robert MacLeod,Jeffrey M. Besterman,Arkadii Vaisburg	24
5	SAR around (l)-S-adenosyl-l-homocysteine, an inhibitor of human DNA methyltransferase (DNMT) enzymes 2009 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),(unknown),David B. Llewellyn,(unknown),Naomy Bernstein,Stephen Claridge,Franck Raeppel,Arkadii Vaisburg,Nadine H. Elowe,(unknown),Jubrail Rahil,(unknown),A. Robert MacLeod,Daniel Delorme,Jeffrey M. Besterman,Amal Wahhab	35
6	Constrained (l-)-S-adenosyl-l-homocysteine (SAH) analogues as DNA methyltransferase inhibitors 2009 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),(unknown),David B. Llewellyn,Stephen Claridge,(unknown),Naomy Bernstein,Arkadii Vaisburg,Nadine H. Elowe,(unknown),Jubrail Rahil,(unknown),France Gauthier,A. Robert MacLeod,Daniel Delorme,Jeffrey M. Besterman,Amal Wahhab	44
7	MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo 2008 ·Molecular Cancer Therapeutics ·Marielle Fournel,Claire Bonfils,Yu Hou,Pu Yan,Marie-Claude Trachy-Bourget,Ann Kalita,Jianhong Liu,Aihua Lu,(unknown),Marie‐France Robert,Jeffrey Gillespie,Jinru Wang,Hélène Ste-Croix,Jubrail Rahil,Sylvain Lefèbvre,Oscar Moradei,Daniel Delorme,A. Robert MacLeod,Jeffrey M. Besterman,Zuomei Li	271
8	N-Benzyl-1-heteroaryl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamides as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1) 2008 ·Bioorganic & Medicinal Chemistry Letters ·Martin Allan,Sukhdev Manku,Éric Therrien,Natalie Nguyen,(unknown),Marie‐France Robert,Anne-Christine Goulet,(unknown),(unknown),A. Robert MacLeod,Robert Déziel,Jeffrey M. Besterman,Hannah Nguyen,Amal Wahhab	69
9	Overcoming Resistance to Interferon-Induced Apoptosis of Renal Carcinoma and Melanoma Cells by DNA Demethylation 2006 ·Journal of Clinical Oncology ·Frederic J. Reu,Soo In Bae,Leonid Cherkassky,Douglas W. Leaman,Daniel J. Lindner,Normand Beaulieu,A. Robert MacLeod,Ernest C. Borden	97
10	Release of Methyl CpG Binding Proteins and Histone Deacetylase 1 from the Estrogen Receptor α (ER) Promoter upon Reactivation in ER-Negative Human Breast Cancer Cells 2005 ·Molecular Endocrinology ·Dipali Sharma,(unknown),Xiaowei Yang,Normand Beaulieu,A. Robert MacLeod,Nancy E. Davidson	128
11	(2-Amino-phenyl)-amides of ω-substituted alkanoic acids as new histone deacetylase inhibitors 2003 ·Bioorganic & Medicinal Chemistry Letters ·Arkadii Vaisburg,Naomy Bernstein,Sylvie Fréchette,Martin Allan,(unknown),Silvana Leit,Oscar Moradei,Giliane Bouchain,Jinru Wang,Soon Hyung Woo,Marielle Fournel,Pu Yan,Marie-Claude Trachy-Bourget,Ann Kalita,Carole Beaulieu,Zuomei Li,A. Robert MacLeod,Jeffrey M. Besterman,Daniel Delorme	21
12	A phase I pharmacokinetic and pharmacodynamic study of the DNA methyltransferase 1 inhibitor MG98 administered twice weekly 2003 ·Annals of Oncology ·David J. Stewart,Ross C. Donehower,Elizabeth A. Eisenhauer,Nancy Wainman,Ajit Shah,Claire Bonfils,A. Robert MacLeod,Jeffrey M. Besterman,Gregory K. Reid	77
13	Development of Potential Antitumor Agents. Synthesis and Biological Evaluation of a New Set of Sulfonamide Derivatives as Histone Deacetylase Inhibitors 2003 ·Journal of Medicinal Chemistry ·Giliane Bouchain,Silvana Leit,Sylvie Fréchette,(unknown),(unknown),Oscar Moradei,Soon Hyung Woo,Marielle Fournel,Pu Yan,Ann Kalita,Marie-Claude Trachy-Bourget,Carole Beaulieu,Zuomei Li,Marie‐France Robert,A. Robert MacLeod,Jeffrey M. Besterman,Daniel Delorme	52
14	DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cellsbreakdown → 2002 ·Nature Genetics ·Marie‐France Robert,Steves Morin,Normand Beaulieu,France Gauthier,Ian C. Chute,Annie Barsalou,A. Robert MacLeod	507
15	An Essential Role for DNA Methyltransferase DNMT3B in Cancer Cell Survival 2002 ·Journal of Biological Chemistry ·Normand Beaulieu,Steves Morin,Ian C. Chute,Marie‐France Robert,Hannah Nguyen,A. Robert MacLeod	124
16	Characterization of the Human DNA Methyltransferase Splice Variant Dnmt1b 2000 ·Journal of Biological Chemistry ·Claire Bonfils,Normand Beaulieu,Eric Y. Chan,(unknown),A. Robert MacLeod	33
17	Down-regulation of Human DNA-(Cytosine-5) Methyltransferase Induces Cell Cycle Regulators p16 and p21WAF/Cip1 by Distinct Mechanisms 1999 ·Journal of Biological Chemistry ·Marielle Fournel,Przemysław Sapieha,Normand Beaulieu,Jeffrey M. Besterman,A. Robert MacLeod	93
18	Regulation of DNA Methylation by the Ras Signaling Pathway 1995 ·Journal of Biological Chemistry ·A. Robert MacLeod,(unknown),Moshe Szyf	161
19	Expression of Antisense to DNA Methyltransferase mRNA Induces DNA Demethylation and Inhibits Tumorigenesis 1995 ·Journal of Biological Chemistry ·A. Robert MacLeod,Moshe Szyf	140
20	Regulation of the DNA Methyltransferase by the Ras-AP-1 Signaling Pathway 1995 ·Journal of Biological Chemistry ·(unknown),A. Robert MacLeod,Moshe Szyf	119

About A. Robert MacLeod

A. Robert MacLeod is a scholar working on Aging, Molecular Biology and Hepatology, having authored 26 papers that have together received 2.5k indexed citations. Recurring topics across this work include Epigenetics and DNA Methylation (18 papers), Cancer-related gene regulation (10 papers) and RNA modifications and cancer (8 papers). The work is most often cited by research in Molecular Biology (2.2k citations), Cancer Research (233 citations) and Oncology (353 citations). A. Robert MacLeod has collaborated with scholars based in Canada, United States and France. Frequent co-authors include Moshe Szyf, Normand Beaulieu, Marie‐France Robert, Steves Morin, Ian C. Chute, France Gauthier, Annie Barsalou, Jeffrey M. Besterman, Marielle Fournel and Claire Bonfils. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Genetics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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