A. Robert MacLeod

3.4k total citations · 1 hit paper
26 papers, 2.5k citations indexed

About

A. Robert MacLeod is a scholar working on Molecular Biology, Immunology and Hepatology. According to data from OpenAlex, A. Robert MacLeod has authored 26 papers receiving a total of 2.5k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 3 papers in Immunology and 2 papers in Hepatology. Recurrent topics in A. Robert MacLeod's work include Epigenetics and DNA Methylation (18 papers), Cancer-related gene regulation (10 papers) and RNA modifications and cancer (8 papers). A. Robert MacLeod is often cited by papers focused on Epigenetics and DNA Methylation (18 papers), Cancer-related gene regulation (10 papers) and RNA modifications and cancer (8 papers). A. Robert MacLeod collaborates with scholars based in Canada, United States and France. A. Robert MacLeod's co-authors include Moshe Szyf, Normand Beaulieu, Marie‐France Robert, Steves Morin, Ian C. Chute, France Gauthier, Annie Barsalou, Jeffrey M. Besterman, Marielle Fournel and Claire Bonfils and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Genetics.

In The Last Decade

A. Robert MacLeod

26 papers receiving 2.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

2002 507 citations Marie‐France Robert, Steves Morin et al. Nature Genetics profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
A. Robert MacLeod Canada	22	2.2k	353	329	233	148	26	2.5k
Christine B. Yoo United States	16	3.1k 1.4×	326 0.9×	416 1.3×	415 1.8×	205 1.4×	17	3.5k
Douglas C. Marchion United States	23	1.8k 0.8×	609 1.7×	151 0.5×	253 1.1×	156 1.1×	66	2.3k
Cem Elbi United States	23	1.4k 0.6×	462 1.3×	397 1.2×	219 0.9×	197 1.3×	38	2.2k
Wenlin Shao United States	14	1.5k 0.7×	480 1.4×	754 2.3×	238 1.0×	178 1.2×	27	2.0k
Konstantin Galaktionov United States	12	2.3k 1.1×	1.1k 3.1×	187 0.6×	188 0.8×	191 1.3×	13	2.8k
Alexsandra Espejo United States	19	2.4k 1.1×	293 0.8×	176 0.5×	163 0.7×	104 0.7×	26	2.6k
Oronza A. Botrugno Italy	19	1.6k 0.7×	460 1.3×	265 0.8×	183 0.8×	156 1.1×	30	2.1k
Denis Drygin United States	18	2.2k 1.0×	600 1.7×	106 0.3×	232 1.0×	130 0.9×	41	2.7k
Clark M. Whitehead United States	17	988 0.5×	380 1.1×	167 0.5×	178 0.8×	90 0.6×	24	1.5k
Holger Hess‐Stumpp Germany	18	973 0.4×	307 0.9×	136 0.4×	430 1.8×	163 1.1×	34	1.5k

Countries citing papers authored by A. Robert MacLeod

Since Specialization

Citations

This map shows the geographic impact of A. Robert MacLeod's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by A. Robert MacLeod with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites A. Robert MacLeod more than expected).

Fields of papers citing papers by A. Robert MacLeod

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by A. Robert MacLeod. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by A. Robert MacLeod. The network helps show where A. Robert MacLeod may publish in the future.

Co-authorship network of co-authors of A. Robert MacLeod

This figure shows the co-authorship network connecting the top 25 collaborators of A. Robert MacLeod. A scholar is included among the top collaborators of A. Robert MacLeod based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with A. Robert MacLeod. A. Robert MacLeod is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ningarhari, Massih, Stefano Caruso, Théo Z. Hirsch, et al.. (2020). Telomere length is key to hepatocellular carcinoma diversity and telomerase addiction is an actionable therapeutic target. Journal of Hepatology. 74(5). 1155–1166. 73 indexed citations

Gaudette, Frédéric, Stéphane Raeppel, Hannah Nguyen, et al.. (2010). Identification of potent and selective VEGFR receptor tyrosine kinase inhibitors having new amide isostere headgroups. Bioorganic & Medicinal Chemistry Letters. 20(3). 848–852. 16 indexed citations

Raeppel, Stéphane, Frédéric Gaudette, Michael R. Mannion, et al.. (2010). Identification of a novel series of potent RON receptor tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 20(9). 2745–2749. 11 indexed citations

Claridge, Stephen, Franck Raeppel, Stéphane Raeppel, et al.. (2009). N3-Arylmalonamides: A new series of thieno[3,2-b]pyridine based inhibitors of c-Met and VEGFR2 tyrosine kinases. Bioorganic & Medicinal Chemistry Letters. 19(24). 6836–6839. 24 indexed citations

Llewellyn, David B., Naomy Bernstein, Stephen Claridge, et al.. (2009). SAR around (l)-S-adenosyl-l-homocysteine, an inhibitor of human DNA methyltransferase (DNMT) enzymes. Bioorganic & Medicinal Chemistry Letters. 19(10). 2747–2751. 35 indexed citations

Llewellyn, David B., Stephen Claridge, Naomy Bernstein, et al.. (2009). Constrained (l-)-S-adenosyl-l-homocysteine (SAH) analogues as DNA methyltransferase inhibitors. Bioorganic & Medicinal Chemistry Letters. 19(10). 2742–2746. 44 indexed citations

Fournel, Marielle, Claire Bonfils, Yu Hou, et al.. (2008). MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo. Molecular Cancer Therapeutics. 7(4). 759–768. 271 indexed citations

Allan, Martin, Sukhdev Manku, Éric Therrien, et al.. (2008). N-Benzyl-1-heteroaryl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamides as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1). Bioorganic & Medicinal Chemistry Letters. 19(4). 1218–1223. 69 indexed citations

Reu, Frederic J., Soo In Bae, Leonid Cherkassky, et al.. (2006). Overcoming Resistance to Interferon-Induced Apoptosis of Renal Carcinoma and Melanoma Cells by DNA Demethylation. Journal of Clinical Oncology. 24(23). 3771–3779. 97 indexed citations

10.

Sharma, Dipali, et al.. (2005). Release of Methyl CpG Binding Proteins and Histone Deacetylase 1 from the Estrogen Receptor α (ER) Promoter upon Reactivation in ER-Negative Human Breast Cancer Cells. Molecular Endocrinology. 19(7). 1740–1751. 128 indexed citations

11.

Vaisburg, Arkadii, Naomy Bernstein, Sylvie Fréchette, et al.. (2003). (2-Amino-phenyl)-amides of ω-substituted alkanoic acids as new histone deacetylase inhibitors. Bioorganic & Medicinal Chemistry Letters. 14(1). 283–287. 21 indexed citations

12.

Stewart, David J., Ross C. Donehower, Elizabeth A. Eisenhauer, et al.. (2003). A phase I pharmacokinetic and pharmacodynamic study of the DNA methyltransferase 1 inhibitor MG98 administered twice weekly. Annals of Oncology. 14(5). 766–774. 77 indexed citations

13.

Bouchain, Giliane, Silvana Leit, Sylvie Fréchette, et al.. (2003). Development of Potential Antitumor Agents. Synthesis and Biological Evaluation of a New Set of Sulfonamide Derivatives as Histone Deacetylase Inhibitors. Journal of Medicinal Chemistry. 46(5). 820–830. 52 indexed citations

14.

Robert, Marie‐France, Steves Morin, Normand Beaulieu, et al.. (2002). DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells. Nature Genetics. 33(1). 61–65. 507 indexed citations breakdown →

15.

Beaulieu, Normand, Steves Morin, Ian C. Chute, et al.. (2002). An Essential Role for DNA Methyltransferase DNMT3B in Cancer Cell Survival. Journal of Biological Chemistry. 277(31). 28176–28181. 124 indexed citations

16.

Bonfils, Claire, et al.. (2000). Characterization of the Human DNA Methyltransferase Splice Variant Dnmt1b. Journal of Biological Chemistry. 275(15). 10754–10760. 33 indexed citations

17.

Fournel, Marielle, Przemysław Sapieha, Normand Beaulieu, Jeffrey M. Besterman, & A. Robert MacLeod. (1999). Down-regulation of Human DNA-(Cytosine-5) Methyltransferase Induces Cell Cycle Regulators p16 and p21WAF/Cip1 by Distinct Mechanisms. Journal of Biological Chemistry. 274(34). 24250–24256. 93 indexed citations

18.

MacLeod, A. Robert, et al.. (1995). Regulation of DNA Methylation by the Ras Signaling Pathway. Journal of Biological Chemistry. 270(19). 11327–11337. 161 indexed citations

19.

MacLeod, A. Robert & Moshe Szyf. (1995). Expression of Antisense to DNA Methyltransferase mRNA Induces DNA Demethylation and Inhibits Tumorigenesis. Journal of Biological Chemistry. 270(14). 8037–8043. 140 indexed citations

20.

MacLeod, A. Robert, et al.. (1995). Regulation of the DNA Methyltransferase by the Ras-AP-1 Signaling Pathway. Journal of Biological Chemistry. 270(4). 1595–1601. 119 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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