Standout Papers

Creation of human tumour cells with defined genetic elements 1999 2026 2008 2017 1.8k
  1. Creation of human tumour cells with defined genetic elements (1999)
    William C. Hahn, Christopher M. Counter et al. Nature
  2. Malignant astrocytic glioma: genetics, biology, and paths to treatment (2007)
    Frank B. Furnari, Tim R. Fenton et al. Genes & Development
  3. A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen (2006)
    Jason Moffat, Dorre A. Grueneberg et al. Cell
  4. Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells (2003)
    Sonam Dolma, Stephen L. Lessnick et al. Cancer Cell
  5. Lentivirus-delivered stable gene silencing by RNAi in primary cells (2003)
    Sheila A. Stewart, Derek M. Dykxhoorn et al. RNA
  6. Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9 (2006)
    Andrei V. Krivtsov, David Twomey et al. Nature
  7. Human Keratinocytes That Express hTERT and Also Bypass a p16INK4a-Enforced Mechanism That Limits Life Span Become Immortal yet Retain Normal Growth and Differentiation Characteristics (2000)
    Mark A. Dickson, William C. Hahn et al. Molecular and Cellular Biology
  8. Inhibition of telomerase limits the growth of human cancer cells (1999)
    William C. Hahn, Sheila A. Stewart et al. Nature Medicine
  9. Recurrent BRAF mutations in Langerhans cell histiocytosis (2010)
    Gayane Badalian‐Very, Jo‐Anne Vergilio et al. Blood
  10. Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling (2011)
    Nikhil Wagle, W. Marston Linehan et al. Journal of Clinical Oncology
  11. Rules for Making Human Tumor Cells (2002)
    William C. Hahn, Robert A. Weinberg New England Journal of Medicine
  12. Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells (2001)
    Brian Elenbaas, Lisa Spirio et al. Genes & Development
  13. Modelling the molecular circuitry of cancer (2002)
    William C. Hahn, Robert A. Weinberg Nature reviews. Cancer
  14. A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells (2004)
    Elizabeth S. Yeh, Melissa Cunningham et al. Nature Cell Biology
  15. KRAS and YAP1 Converge to Regulate EMT and Tumor Survival (2014)
    Diane D. Shao, Wen Xue et al. Cell
  16. Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants (2005)
    Heidi Greulich, Tzu-Hsiu Chen et al. PLoS Medicine
  17. Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization (1998)
    Christopher M. Counter, William C. Hahn et al. Proceedings of the National Academy of Sciences
  18. Emerging insights into the molecular and cellular basis of glioblastoma (2012)
    Gavin P. Dunn, Mikael L. Rinne et al. Genes & Development
  19. Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations (2013)
    Priscilla K. Brastianos, Peleg Horowitz et al. Nature Genetics
  20. A Melanoma Cell State Distinction Influences Sensitivity to MAPK Pathway Inhibitors (2014)
    David J. Konieczkowski, Cory M. Johannessen et al. Cancer Discovery
  21. Chemosensitivity linked to p73 function (2003)
    Meredith S. Irwin, Keiichi Kondo et al. Cancer Cell
  22. Biologically informed deep neural network for prostate cancer discovery (2021)
    Haitham Elmarakeby, Justin H. Hwang et al. Nature
  23. Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects (2021)
    Joshua M. Dempster, Isabella Boyle et al. Genome biology

Immediate Impact

10 by Nobel laureates 50 from Science/Nature 121 standout
Sub-graph 1 of 17

Citing Papers

Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 Standout
2 intermediate papers

Works of William C. Hahn being referenced

A Leucine-Rich Repeat Protein Provides a SHOC2 the RAS Circuit: a Structure-Function Perspective
2021
High-Throughput Detection of Actionable Genomic Alterations in Clinical Tumor Samples by Targeted, Massively Parallel Sequencing
2011
and 1 more

Author Peers

Author Last Decade Papers Cites
William C. Hahn 26136 11079 7690 289 40.1k
Lynda Chin 20167 9178 6652 159 29.0k
Amato J. Giaccia 22859 10629 17174 346 39.7k
Richard G. Pestell 32954 15007 13379 459 49.3k
Hiroyuki Aburatani 23941 8249 7475 525 37.3k
Johannes L. Bos 25358 11047 5178 244 39.3k
Chi V. Dang 38321 9323 23758 299 52.1k
Julian Downward 29860 11325 4843 289 41.2k
René Bernards 30065 16140 9590 319 43.5k
David J. Kwiatkowski 15671 7242 3800 390 32.7k
William G. Kaelin 35237 14721 22252 244 49.6k

All Works

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2026