Standout Papers

The fundamental role of epigenetic events in cancer 1999 2026 2008 2017 4.3k
  1. The fundamental role of epigenetic events in cancer (2002)
    Peter A. Jones, Stephen B. Baylin Nature Reviews Genetics
  2. The Epigenomics of Cancer (2007)
    Peter A. Jones, Stephen B. Baylin Cell
  3. Gene Silencing in Cancer in Association with Promoter Hypermethylation (2003)
    James G. Herman, Stephen B. Baylin New England Journal of Medicine
  4. A decade of exploring the cancer epigenome — biological and translational implications (2011)
    Stephen B. Baylin, Peter A. Jones Nature reviews. Cancer
  5. CpG island methylator phenotype in colorectal cancer (1999)
    Minoru Toyota, Nita Ahuja et al. Proceedings of the National Academy of Sciences
  6. Inactivation of the DNA-Repair GeneMGMTand the Clinical Response of Gliomas to Alkylating Agents (2000)
    Manel Esteller, Jesús García‐Foncillas et al. New England Journal of Medicine
  7. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers (1995)
    Adrian Merlo, James G. Herman et al. Nature Medicine
  8. A gene hypermethylation profile of human cancer. (2001)
    Manel Esteller, Paul G. Corn et al. PubMed
  9. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma (1998)
    James G. Herman, Asad Umar et al. Proceedings of the National Academy of Sciences
  10. DNA hypermethylation in tumorigenesis: epigenetics joins genetics (2000)
    Stephen B. Baylin, James G. Herman Trends in Genetics
  11. Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction? (2006)
    Stephen B. Baylin, Joyce E. Ohm Nature reviews. Cancer
  12. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. (1995)
    James G. Herman, Adrian Merlo et al. PubMed
  13. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells (2002)
    Ina Rhee, Kurtis E. Bachman et al. Nature
  14. Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon (1994)
    Jean‐Pierre J. Issa, Yvonne Ottaviano et al. Nature Genetics
  15. Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer (2003)
    D. Neil Watkins, David M. Berman et al. Nature
  16. DNA methylation and gene silencing in cancer (2005)
    Stephen B. Baylin Nature Clinical Practice Oncology
  17. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer (2004)
    Hiromu Suzuki, D. Neil Watkins et al. Nature Genetics
  18. Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer (2006)
    Anju Singh, Vikas Misra et al. PLoS Medicine
  19. Epigenetic Determinants of Cancer (2016)
    Stephen B. Baylin, Peter A. Jones Cold Spring Harbor Perspectives in Biology
  20. A stem cell–like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing (2007)
    Joyce E. Ohm, Kelly M. McGarvey et al. Nature Genetics
  21. Targeting the cancer epigenome for therapy (2016)
    Peter A. Jones, Jean‐Pierre J. Issa et al. Nature Reviews Genetics
  22. Aberrant methylation of p16 INK4a is an early event in lung cancer and a potential biomarker for early diagnosis (1998)
    Steven A. Belinsky, Kristen J. Nikula et al. Proceedings of the National Academy of Sciences
  23. Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients. (1999)
    Manel Esteller, Montse Sánchez‐Céspedes et al. PubMed
  24. Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer (2001)
    Stephen B. Baylin Human Molecular Genetics
  25. A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer (2002)
    Hiromu Suzuki, Edward Gabrielson et al. Nature Genetics
  26. E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas. (1995)
    Jeremy R. Graff, James G. Herman et al. PubMed
  27. Predicting lung cancer by detecting aberrant promoter methylation in sputum. (2000)
    William A. Palmisano, Kevin K. Divine et al. PubMed
  28. Tumor Suppressor HIC1 Directly Regulates SIRT1 to Modulate p53-Dependent DNA-Damage Responses (2005)
    Wenyong Chen, David H. Wang et al. Cell
  29. Aging and DNA methylation in colorectal mucosa and cancer. (1998)
    Nita Ahuja, Qing Li et al. PubMed

Immediate Impact

6 by Nobel laureates 54 from Science/Nature 142 standout
Sub-graph 1 of 17

Citing Papers

Function and information content of DNA methylation
2015 StandoutNature
Insulator dysfunction and oncogene activation in IDH mutant gliomas
2015 StandoutNature
53 intermediate papers

Works of Stephen B. Baylin being referenced

A decade of exploring the cancer epigenome — biological and translational implications
2011 Standout
High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer.
1991
and 39 more

Author Peers

Author Last Decade Papers Cites
Stephen B. Baylin 59506 15781 13546 443 75.7k
James G. Herman 50175 14879 13378 393 64.8k
Michael B. Sporn 44382 12664 8534 507 72.8k
Ronald A. DePinho 55409 22760 13587 416 84.9k
David Sidransky 39508 25258 16833 572 65.1k
Curtis C. Harris 40543 21985 24469 571 65.7k
Roderick T. Bronson 45554 22954 11505 543 76.8k
Carl‐Henrik Heldin 41421 13948 8881 492 62.1k
Victor E. Velculescu 34053 20138 16698 182 53.4k
Carlos Cordon‐Cardo 40955 22560 12688 563 67.3k
Peter A. Jones 48140 8151 10709 350 60.4k

All Works

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