Standout Papers

The Steroid and Thyroid Hormone Receptor Superfamily 1983 2026 1997 2011 6.3k
  1. The Steroid and Thyroid Hormone Receptor Superfamily (1988)
    Ronald M. Evans Science
  2. The nuclear receptor superfamily: The second decade (1995)
    David J. Mangelsdorf, Carl S. Thummel et al. Cell
  3. The RXR heterodimers and orphan receptors (1995)
    David J. Mangelsdorf, Ronald M. Evans Cell
  4. 15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ (1995)
    Barry M. Forman, Peter Tontonoz et al. Cell
  5. Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing (1983)
    Michael G. Rosenfeld, Jean‐Jacques Mermod et al. Nature
  6. Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products (1982)
    Susan Amara, Vivian Jonas et al. Nature
  7. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ (1997)
    Barry M. Forman, Jasmine Chen et al. Proceedings of the National Academy of Sciences
  8. Identification of a receptor for the morphogen retinoic acid (1987)
    Vincent Giguère, Estelita S. Ong et al. Nature
  9. Nuclear Receptors and Lipid Physiology: Opening the X-Files (2001)
    Ajay Chawla, Joyce J. Repa et al. Science
  10. PPARγ Is Required for Placental, Cardiac, and Adipose Tissue Development (1999)
    Yaacov Barak, Michael C. Nelson et al. Molecular Cell
  11. Cloning of Human Mineralocorticoid Receptor Complementary DNA: Structural and Functional Kinship with the Glucocorticoid Receptor (1987)
    Jeffrey L. Arriza, Cary Weinberger et al. Science
  12. Oxidized LDL Regulates Macrophage Gene Expression through Ligand Activation of PPARγ (1998)
    László Nagy, Peter Tontonoz et al. Cell
  13. 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor (1992)
    Richard A. Heyman, David J. Mangelsdorf et al. Cell
  14. A transcriptional co-repressor that interacts with nuclear hormone receptors (1995)
    Ronald M. Evans et al. Nature
  15. PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL (1998)
    Peter Tontonoz, László Nagy et al. Cell
  16. Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors (1991)
    Kazuhiko Umesono, Catherine C. Thompson et al. Cell
  17. PPARγ signaling and metabolism: the good, the bad and the future (2013)
    Maryam Ahmadian, Jae Myoung Suh et al. Nature Medicine
  18. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors (1992)
    Steven A. Kliewer, Kazuhiko Umesono et al. Nature
  19. Primary structure and expression of a functional human glucocorticoid receptor cDNA (1985)
    Stanley M. Hollenberg, Cary Weinberger et al. Nature
  20. Nuclear receptor that identifies a novel retinoic acid response pathway (1990)
    David J. Mangelsdorf, Estelita S. Ong et al. Nature
  21. PPARs and the complex journey to obesity (2004)
    Ronald M. Evans, Grant D. Barish et al. Nature Medicine
  22. Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling (1992)
    Steven A. Kliewer, Kazuhiko Umesono et al. Nature
  23. The c-erb-A gene encodes a thyroid hormone receptor (1986)
    Cary Weinberger, Catherine C. Thompson et al. Nature
  24. Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300 (1997)
    Richard J. Lin, R. Louis Schiltz et al. Cell
  25. Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML (1991)
    Akira Kakizuka, Wilson H. Miller et al. Cell
  26. Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. (1994)
    Steven A. Kliewer, Barry M. Forman et al. Proceedings of the National Academy of Sciences
  27. A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis (2001)
    Ajay Chawla, William A. Boisvert et al. Molecular Cell
  28. Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells (2011)
    Ryan Lister, Mattia Pelizzola et al. Nature
  29. Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor (1990)
    Roland Schüle, Pundi N. Rangarajan et al. Cell
  30. Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity (2003)
    Yong‐Xu Wang, Chih‐Hao Lee et al. Cell
  31. Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A, and Histone Deacetylase (1997)
    László Nagy, Hung‐Ying Kao et al. Cell
  32. Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. (1992)
    David J. Mangelsdorf, Uwe Borgmeyer et al. Genes & Development
  33. Identification of a nuclear receptor that is activated by farnesol metabolites (1995)
    Barry M. Forman, Elizabeth C. Goode et al. Cell
  34. AMPK and PPARδ Agonists Are Exercise Mimetics (2008)
    Vihang A. Narkar, Michael Downes et al. Cell
  35. PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation (2001)
    Ajay Chawla, Yaacov Barak et al. Nature Medicine
  36. Calcitonin gene-related peptide immunoreactivity in the spinal cord of man and of eight other species (1984)
    S.J. Gibson, J.M. Polak et al. Journal of Neuroscience
  37. Role of the histone deacetylase complex in acute promyelocytic leukaemia (1998)
    Richard J. Lin, László Nagy et al. Nature
  38. LXR, a nuclear receptor that defines a distinct retinoid response pathway. (1995)
    Kazuhiko Umesono, Estelita S. Ong et al. Genes & Development
  39. Dramatic growth of mice that develop from eggs microinjected with metallothionein–growth hormone fusion genes (1982)
    Richard D. Palmiter, Ralph L. Brinster et al. Nature
  40. Vitamin D Receptor As an Intestinal Bile Acid Sensor (2002)
    Makoto Makishima, Timothy T. Lu et al. Science
  41. Regulation of Muscle Fiber Type and Running Endurance by PPARδ (2004)
    Chun‐Li Zhang, Ruth T. Yu et al. PLoS Biology
  42. Nuclear Receptors, RXR, and the Big Bang (2014)
    Ronald M. Evans, David J. Mangelsdorf Cell
  43. Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β (2012)
    Han Cho, Xuan Zhao et al. Nature
  44. Anatomical Profiling of Nuclear Receptor Expression Reveals a Hierarchical Transcriptional Network (2006)
    Angie L. Bookout, Yangsik Jeong et al. Cell
  45. Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle (2003)
    Weimin He, Yaacov Barak et al. Proceedings of the National Academy of Sciences
  46. Role of CBP/P300 in nuclear receptor signalling (1996)
    Debabrata Chakravarti, Vickie J. LaMorte et al. Nature
  47. Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion (2016)
    Cristovão M. Sousa, Douglas E. Biancur et al. Nature
  48. Determinants of target gene specificity for steroid/thyroid hormone receptors (1989)
    Kazuhiko Umesono, Ronald M. Evans Cell
  49. Functional ecdysone receptor is the product of EcR and Ultraspiracle genes (1993)
    Tso‐Pang Yao, Barry M. Forman et al. Nature
  50. Nuclear Receptor Expression Links the Circadian Clock to Metabolism (2006)
    Xiaoyong Yang, Michael Downes et al. Cell
  51. SXR, a novel steroid and xenobioticsensing nuclear receptor (1998)
    Bruce Blumberg, Walid Sabbagh et al. Genes & Development
  52. Functional domains of the human glucocorticoid receptor (1986)
    Vincent Giguère, Stanley M. Hollenberg et al. Cell
  53. Identification of a new class of steroid hormone receptors (1988)
    Vincent Giguère, Na Yang et al. Nature
  54. Terminal Differentiation of Human Breast Cancer through PPARγ (1998)
    Elisabetta Mueller, Pasha Sarraf et al. Molecular Cell
  55. Minireview: Lipid Metabolism, Metabolic Diseases, and Peroxisome Proliferator-Activated Receptors (2003)
    Chih‐Hao Lee, Peter Olson et al. Endocrinology
  56. AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation (2009)
    Katja Lamia, Uma M. Sachdeva et al. Science
  57. Zinc fingers: Gilt by association (1988)
    Ronald M. Evans Cell
  58. A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein (1994)
    Jacqueline A. Dyck, Gerd G. Maul et al. Cell
  59. Ecdysone-inducible gene expression in mammalian cells and transgenic mice. (1996)
    David No, Tianliang Yao et al. Proceedings of the National Academy of Sciences
  60. Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation (1992)
    Tso-Pang Yao, William A. Segraves et al. Cell
  61. Multiple and cooperative trans-activation domains of the human glucocorticoid receptor (1988)
    Stanley M. Hollenberg, Ronald M. Evans Cell
  62. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids (2001)
    Wen Xie, Anna Radomińska‐Pandya et al. Proceedings of the National Academy of Sciences
  63. A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR (1991)
    David J. Mangelsdorf, Kazuhiko Umesono et al. Cell
  64. Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor γ and the retinoid X receptor (1997)
    Peter Tontonoz, Samuel Singer et al. Proceedings of the National Academy of Sciences
  65. Unique response pathways are established by allosteric interactions among nuclear hormone receptors (1995)
    Barry M. Forman, Kazuhiko Umesono et al. Cell
  66. A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance (2012)
    Keisuke Ito, Arkaitz Carracedo et al. Nature Medicine
  67. Humanized xenobiotic response in mice expressing nuclear receptor SXR (2000)
    Wen Xie, Joyce L. Barwick et al. Nature
  68. Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist (1989)
    Klaus Damm, Catherine C. Thompson et al. Nature
  69. Regulation of Hormone-Induced Histone Hyperacetylation and Gene Activation via Acetylation of an Acetylase (1999)
    Hong-Wu Chen, Richard J. Lin et al. Cell
  70. Expression in Brain of a Messenger RNA Encoding a Novel Neuropeptide Homologous to Calcitonin Gene-Related Peptide (1985)
    Susan Amara, Jeffrey L. Arriza et al. Science
  71. RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. (1994)
    Henry M. Sucov, E. D. Dyson et al. Genes & Development
  72. Retinoic acid and thyroid hormone induce gene expression through a common responsive element (1988)
    Kazuhiko Umesono, Vincent Giguère et al. Nature
  73. The neuronal mineralocorticoid eeceptor as a mediator of glucocorticoid response (1988)
    Jeffrey L. Arriza, Richard B. Simerly et al. Neuron
  74. A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response (2013)
    Ning Ding, Ruth T. Yu et al. Cell
  75. FXR Regulates Intestinal Cancer Stem Cell Proliferation (2019)
    Ting Fu, Sally Coulter et al. Cell
  76. Immune-evasive human islet-like organoids ameliorate diabetes (2020)
    Eiji Yoshihara, Carolyn O’Connor et al. Nature
  77. A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis (2020)
    Tae Gyu Oh, Susy M. Kim et al. Cell Metabolism

Immediate Impact

30 by Nobel laureates 87 from Science/Nature 167 standout
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Citing Papers

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Works of Ronald M. Evans being referenced

The starvation hormone, fibroblast growth factor-21, extends lifespan in mice
2012
Thyroid hormone receptor repression is linked to type I pneumocyte–associated respiratory distress syndrome
2011

Author Peers

Author Last Decade Papers Cites
Ronald M. Evans 95165 41538 18602 19767 619 146.4k
Pierre Chambon 80127 45125 8964 5101 697 115.9k
Christopher K. Glass 60633 17811 6345 9868 372 94.9k
Michael G. Rosenfeld 54392 22282 10667 4828 388 78.4k
Jan-Ακε Gustafsson 33183 38125 4803 5908 1.2k 83.9k
Michael Karin 112099 15109 7761 13745 646 209.7k
David J. Mangelsdorf 39650 14892 4769 7180 221 69.2k
Lewis C. Cantley 103801 7127 5743 11492 702 148.2k
Bert W. O’Malley 40333 35425 5249 3667 961 77.0k
Frank J. Gonzalez 55848 8343 2740 16492 1.3k 117.1k
Bruce M. Spiegelman 72203 8006 5307 70072 344 135.0k

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