Standout Papers

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint 2006 2026 2012 2019 3.0k
  1. AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint (2008)
    Dana M. Gwinn, David B. Shackelford et al. Molecular Cell
  2. AMPK: guardian of metabolism and mitochondrial homeostasis (2017)
    Sébastien Herzig, Reuben J. Shaw Nature Reviews Molecular Cell Biology
  3. The AMPK signalling pathway coordinates cell growth, autophagy and metabolism (2011)
    Maria M. Mihaylova, Reuben J. Shaw Nature Cell Biology
  4. Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy (2010)
    David B. Shackelford, Maria M. Mihaylova et al. Science
  5. Ras, PI(3)K and mTOR signalling controls tumour cell growth (2006)
    Reuben J. Shaw, Lewis C. Cantley Nature
  6. The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin (2005)
    Reuben J. Shaw, Katja Lamia et al. Science
  7. The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress (2004)
    Reuben J. Shaw, Nabeel Bardeesy et al. Proceedings of the National Academy of Sciences
  8. The LKB1–AMPK pathway: metabolism and growth control in tumour suppression (2009)
    David B. Shackelford, Reuben J. Shaw Nature reviews. Cancer
  9. AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance (2017)
    Daniel Garcia, Reuben J. Shaw Molecular Cell
  10. AMPK and PPARδ Agonists Are Exercise Mimetics (2008)
    Vihang A. Narkar, Michael Downes et al. Cell
  11. The LKB1 tumor suppressor negatively regulates mTOR signaling (2004)
    Reuben J. Shaw, Nabeel Bardeesy et al. Cancer Cell
  12. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress (2016)
    Sébastien Herzig, Julien Courchet et al. Science
  13. AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation (2009)
    Katja Lamia, Uma M. Sachdeva et al. Science
  14. Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates (2015)
    Matthew G. H. Chun, Mitchell Vamos et al. Molecular Cell
  15. The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR (2011)
    Joungmok Kim, Reuben J. Shaw et al. Autophagy
  16. Autophagic cell death restricts chromosomal instability during replicative crisis (2019)
    Joe Nassour, Robert J. Radford et al. Nature
  17. AMPK: restoring metabolic homeostasis over space and time (2021)
    Elijah Trefts, Reuben J. Shaw Molecular Cell
  18. Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1 (2023)
    Nazma Malik, Bibiana I. Ferreira et al. Science

Immediate Impact

16 by Nobel laureates 67 from Science/Nature 216 standout
Sub-graph 1 of 14

Citing Papers

The gut microbiota reprograms intestinal lipid metabolism through long noncoding RNA Snhg9
2023 StandoutScience
Circadian alignment of early onset caloric restriction promotes longevity in male C57BL/6J mice
2022 StandoutScience
26 intermediate papers

Works of Reuben J. Shaw being referenced

AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation
2009 StandoutScience
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
and 5 more

Author Peers

Author Last Decade Papers Cites
Reuben J. Shaw 20255 5228 4250 7442 85 29.5k
Brendan D. Manning 21580 4801 2433 3513 113 30.2k
Ormond A. MacDougald 13081 3408 2217 4822 166 22.4k
Robert V. Farese 17622 3534 5558 5007 236 34.3k
Pere Puigserver 25518 4661 3406 8539 121 43.1k
Morris J. Birnbaum 27376 3589 8271 5560 242 40.7k
David Carling 28508 3568 11822 8131 181 40.0k
Benoı̂t Viollet 26757 4907 9541 10690 340 41.4k
Jason K. Kim 13321 1634 3614 6483 198 24.9k
Leonard Guarente 28560 4006 1487 10329 204 54.1k
Evan D. Rosen 12910 2335 1896 7273 106 24.6k

All Works

Loading papers...

Rankless by CCL
2026